Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 SIGMAR1 2件: Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases D00848 Dextromethorphan 11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
2 SIGMAR1 2件: Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases D03742 Dextromethorphan 11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
3 SIGMAR1 2件: Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases D03744 Dextromethorphan 11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
4 SIGMAR1 2件: Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases D11383 Blarcamesine 1件: 156
5 SLC22A12 - D01056 Benzbromarone 1件: 86
6 S1PR1 3件: FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D10001 Fingolimod 3件: 13, 14, 156
7 S1PR1 3件: FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D10930 Etrasimod 3件: 96, 97, 98
8 S1PR1 3件: FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D10968 Ozanimod 3件: 13, 96, 97
9 S1PR1 3件: FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D11215 Ponesimod 1件: 13
10 S1PR1 3件: FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D11283 Cenerimod 1件: 49
11 S1PR1 3件: FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D11460 Siponimod 2件: 13, 50
12 S1PR3 2件: Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D10930 Etrasimod 3件: 96, 97, 98
13 S1PR3 2件: Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D10968 Ozanimod 3件: 13, 96, 97
14 SV2C 1件: ECM-receptor interaction D11842 Padsevonil 1件: 149
15 SIGLEC8 - D11906 Lirentelimab 1件: 98
16 SERPIND1 1件: Complement and coagulation cascades D08547 Sulodexide 4件: 13, 51, 271, 288
17 SMAD7 2件: TGF-beta signaling pathway, Hippo signaling pathway D10956 Mongersen 2件: 96, 97
18 SERPINC1 1件: Complement and coagulation cascades D03674 Enoxaparin 1件: 46
19 SERPINC1 1件: Complement and coagulation cascades D07510 Heparin 12件: 47, 60, 70, 79, 84, 107, 224, 226, 280, 299, 316, 317
20 SERPINC1 1件: Complement and coagulation cascades D07510 Enoxaparin 1件: 46
21 SERPINC1 1件: Complement and coagulation cascades D07510 Parnaparin 1件: 97
22 SERPINC1 1件: Complement and coagulation cascades D08547 Sulodexide 4件: 13, 51, 271, 288
23 SOST 2件: Wnt signaling pathway, Parathyroid hormone synthesis, secretion and action D10156 Romosozumab 1件: 274
24 S1PR5 2件: Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D10930 Etrasimod 3件: 96, 97, 98
25 S1PR5 2件: Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D10968 Ozanimod 3件: 13, 96, 97
26 S1PR5 2件: Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D11460 Siponimod 2件: 13, 50
27 SLAMF7 - D09337 Elotuzumab 2件: 28, 300
28 SCN1A 1件: Dopaminergic synapse D00252 Carbamazepine 2件: 13, 231
29 SCN1A 1件: Dopaminergic synapse D00354 Lamotrigine 5件: 13, 34, 38, 114, 144
30 SCN1A 1件: Dopaminergic synapse D00358 Lidocaine 13件: 6, 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256
31 SCN1A 1件: Dopaminergic synapse D00512 Phenytoin 1件: 13
32 SCN1A 1件: Dopaminergic synapse D00533 Oxcarbazepine 1件: 13
33 SCN1A 1件: Dopaminergic synapse D00537 Topiramate 6件: 6, 97, 140, 144, 156, 193
34 SCN1A 1件: Dopaminergic synapse D00538 Zonisamide 1件: 6
35 SCN1A 1件: Dopaminergic synapse D00636 Amiodarone 2件: 28, 127
36 SCN1A 1件: Dopaminergic synapse D00638 Flecainide 1件: 6
37 SCN1A 1件: Dopaminergic synapse D00639 Mexiletine 5件: 1, 2, 10, 113, 114
38 SCN1A 1件: Dopaminergic synapse D00642 Quinidine 3件: 2, 8, 13
39 SCN1A 1件: Dopaminergic synapse D00643 Quinidine 3件: 2, 8, 13
40 SCN1A 1件: Dopaminergic synapse D01287 Levobupivacaine 1件: 46
41 SCN1A 1件: Dopaminergic synapse D01450 Bupivacaine 8件: 46, 51, 53, 70, 96, 168, 226, 298
42 SCN1A 1件: Dopaminergic synapse D01768 Oxybuprocaine 1件: 6
43 SCN1A 1件: Dopaminergic synapse D02086 Lidocaine 13件: 6, 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256
44 SCN1A 1件: Dopaminergic synapse D02103 Phenytoin 1件: 13
45 SCN1A 1件: Dopaminergic synapse D02272 Quinidine 3件: 2, 8, 13
46 SCN1A 1件: Dopaminergic synapse D02910 Amiodarone 2件: 28, 127
47 SCN1A 1件: Dopaminergic synapse D03492 Cibenzoline 1件: 58
48 SCN1A 1件: Dopaminergic synapse D04048 Ropivacaine 3件: 36, 46, 70
49 SCN1A 1件: Dopaminergic synapse D05775 Rufinamide 1件: 144
50 SCN1A 1件: Dopaminergic synapse D07552 Bupivacaine 8件: 46, 51, 53, 70, 96, 168, 226, 298
51 SCN1A 1件: Dopaminergic synapse D07962 Flecainide 1件: 6
52 SCN1A 1件: Dopaminergic synapse D08116 Levobupivacaine 1件: 46
53 SCN1A 1件: Dopaminergic synapse D08127 Lidocaine 13件: 6, 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256
54 SCN1A 1件: Dopaminergic synapse D08215 Mexiletine 5件: 1, 2, 10, 113, 114
55 SCN1A 1件: Dopaminergic synapse D08319 Oxybuprocaine 1件: 6
56 SCN1A 1件: Dopaminergic synapse D08458 Quinidine 3件: 2, 8, 13
57 SCN1A 1件: Dopaminergic synapse D08490 Ropivacaine 3件: 36, 46, 70
58 SCN1A 1件: Dopaminergic synapse D11155 Eleclazine 1件: 58
59 SCN2A 1件: Taste transduction D00252 Carbamazepine 2件: 13, 231
60 SCN2A 1件: Taste transduction D00354 Lamotrigine 5件: 13, 34, 38, 114, 144
61 SCN2A 1件: Taste transduction D00358 Lidocaine 13件: 6, 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256
62 SCN2A 1件: Taste transduction D00512 Phenytoin 1件: 13
63 SCN2A 1件: Taste transduction D00533 Oxcarbazepine 1件: 13
64 SCN2A 1件: Taste transduction D00537 Topiramate 6件: 6, 97, 140, 144, 156, 193
65 SCN2A 1件: Taste transduction D00538 Zonisamide 1件: 6
66 SCN2A 1件: Taste transduction D00636 Amiodarone 2件: 28, 127
67 SCN2A 1件: Taste transduction D00638 Flecainide 1件: 6
68 SCN2A 1件: Taste transduction D00639 Mexiletine 5件: 1, 2, 10, 113, 114
69 SCN2A 1件: Taste transduction D00642 Quinidine 3件: 2, 8, 13
70 SCN2A 1件: Taste transduction D00643 Quinidine 3件: 2, 8, 13
71 SCN2A 1件: Taste transduction D01287 Levobupivacaine 1件: 46
72 SCN2A 1件: Taste transduction D01450 Bupivacaine 8件: 46, 51, 53, 70, 96, 168, 226, 298
73 SCN2A 1件: Taste transduction D01768 Oxybuprocaine 1件: 6
74 SCN2A 1件: Taste transduction D02086 Lidocaine 13件: 6, 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256
75 SCN2A 1件: Taste transduction D02103 Phenytoin 1件: 13
76 SCN2A 1件: Taste transduction D02272 Quinidine 3件: 2, 8, 13
77 SCN2A 1件: Taste transduction D02910 Amiodarone 2件: 28, 127
78 SCN2A 1件: Taste transduction D03492 Cibenzoline 1件: 58
79 SCN2A 1件: Taste transduction D04048 Ropivacaine 3件: 36, 46, 70
80 SCN2A 1件: Taste transduction D05775 Rufinamide 1件: 144
81 SCN2A 1件: Taste transduction D07552 Bupivacaine 8件: 46, 51, 53, 70, 96, 168, 226, 298
82 SCN2A 1件: Taste transduction D07962 Flecainide 1件: 6
83 SCN2A 1件: Taste transduction D08116 Levobupivacaine 1件: 46
84 SCN2A 1件: Taste transduction D08127 Lidocaine 13件: 6, 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256
85 SCN2A 1件: Taste transduction D08215 Mexiletine 5件: 1, 2, 10, 113, 114
86 SCN2A 1件: Taste transduction D08319 Oxybuprocaine 1件: 6
87 SCN2A 1件: Taste transduction D08458 Quinidine 3件: 2, 8, 13
88 SCN2A 1件: Taste transduction D08490 Ropivacaine 3件: 36, 46, 70
89 SCN2A 1件: Taste transduction D11155 Eleclazine 1件: 58
90 SCN3A 1件: Taste transduction D00252 Carbamazepine 2件: 13, 231
91 SCN3A 1件: Taste transduction D00354 Lamotrigine 5件: 13, 34, 38, 114, 144
92 SCN3A 1件: Taste transduction D00358 Lidocaine 13件: 6, 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256
93 SCN3A 1件: Taste transduction D00512 Phenytoin 1件: 13
94 SCN3A 1件: Taste transduction D00533 Oxcarbazepine 1件: 13
95 SCN3A 1件: Taste transduction D00537 Topiramate 6件: 6, 97, 140, 144, 156, 193
96 SCN3A 1件: Taste transduction D00538 Zonisamide 1件: 6
97 SCN3A 1件: Taste transduction D00636 Amiodarone 2件: 28, 127
98 SCN3A 1件: Taste transduction D00638 Flecainide 1件: 6
99 SCN3A 1件: Taste transduction D00639 Mexiletine 5件: 1, 2, 10, 113, 114
100 SCN3A 1件: Taste transduction D00642 Quinidine 3件: 2, 8, 13
101 SCN3A 1件: Taste transduction D00643 Quinidine 3件: 2, 8, 13
102 SCN3A 1件: Taste transduction D01287 Levobupivacaine 1件: 46
103 SCN3A 1件: Taste transduction D01450 Bupivacaine 8件: 46, 51, 53, 70, 96, 168, 226, 298
104 SCN3A 1件: Taste transduction D01768 Oxybuprocaine 1件: 6
105 SCN3A 1件: Taste transduction D02086 Lidocaine 13件: 6, 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256
106 SCN3A 1件: Taste transduction D02103 Phenytoin 1件: 13
107 SCN3A 1件: Taste transduction D02272 Quinidine 3件: 2, 8, 13
108 SCN3A 1件: Taste transduction D02910 Amiodarone 2件: 28, 127
109 SCN3A 1件: Taste transduction D03492 Cibenzoline 1件: 58
110 SCN3A 1件: Taste transduction D04048 Ropivacaine 3件: 36, 46, 70
111 SCN3A 1件: Taste transduction D05775 Rufinamide 1件: 144
112 SCN3A 1件: Taste transduction D07299 Lacosamide 3件: 2, 46, 149
113 SCN3A 1件: Taste transduction D07552 Bupivacaine 8件: 46, 51, 53, 70, 96, 168, 226, 298
114 SCN3A 1件: Taste transduction D07962 Flecainide 1件: 6
115 SCN3A 1件: Taste transduction D08116 Levobupivacaine 1件: 46
116 SCN3A 1件: Taste transduction D08127 Lidocaine 13件: 6, 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256
117 SCN3A 1件: Taste transduction D08215 Mexiletine 5件: 1, 2, 10, 113, 114
118 SCN3A 1件: Taste transduction D08319 Oxybuprocaine 1件: 6
119 SCN3A 1件: Taste transduction D08458 Quinidine 3件: 2, 8, 13
120 SCN3A 1件: Taste transduction D08490 Ropivacaine 3件: 36, 46, 70
121 SCN3A 1件: Taste transduction D11155 Eleclazine 1件: 58
122 SCN5A 1件: Adrenergic signaling in cardiomyocytes D00252 Carbamazepine 2件: 13, 231
123 SCN5A 1件: Adrenergic signaling in cardiomyocytes D00354 Lamotrigine 5件: 13, 34, 38, 114, 144
124 SCN5A 1件: Adrenergic signaling in cardiomyocytes D00358 Lidocaine 13件: 6, 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256
125 SCN5A 1件: Adrenergic signaling in cardiomyocytes D00512 Phenytoin 1件: 13
126 SCN5A 1件: Adrenergic signaling in cardiomyocytes D00533 Oxcarbazepine 1件: 13
127 SCN5A 1件: Adrenergic signaling in cardiomyocytes D00537 Topiramate 6件: 6, 97, 140, 144, 156, 193
128 SCN5A 1件: Adrenergic signaling in cardiomyocytes D00538 Zonisamide 1件: 6
129 SCN5A 1件: Adrenergic signaling in cardiomyocytes D00636 Amiodarone 2件: 28, 127
130 SCN5A 1件: Adrenergic signaling in cardiomyocytes D00638 Flecainide 1件: 6
131 SCN5A 1件: Adrenergic signaling in cardiomyocytes D00639 Mexiletine 5件: 1, 2, 10, 113, 114
132 SCN5A 1件: Adrenergic signaling in cardiomyocytes D00642 Quinidine 3件: 2, 8, 13
133 SCN5A 1件: Adrenergic signaling in cardiomyocytes D00643 Quinidine 3件: 2, 8, 13
134 SCN5A 1件: Adrenergic signaling in cardiomyocytes D01287 Levobupivacaine 1件: 46
135 SCN5A 1件: Adrenergic signaling in cardiomyocytes D01450 Bupivacaine 8件: 46, 51, 53, 70, 96, 168, 226, 298
136 SCN5A 1件: Adrenergic signaling in cardiomyocytes D01768 Oxybuprocaine 1件: 6
137 SCN5A 1件: Adrenergic signaling in cardiomyocytes D02086 Lidocaine 13件: 6, 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256
138 SCN5A 1件: Adrenergic signaling in cardiomyocytes D02103 Phenytoin 1件: 13
139 SCN5A 1件: Adrenergic signaling in cardiomyocytes D02272 Quinidine 3件: 2, 8, 13
140 SCN5A 1件: Adrenergic signaling in cardiomyocytes D02910 Amiodarone 2件: 28, 127
141 SCN5A 1件: Adrenergic signaling in cardiomyocytes D03492 Cibenzoline 1件: 58
142 SCN5A 1件: Adrenergic signaling in cardiomyocytes D04048 Ropivacaine 3件: 36, 46, 70
143 SCN5A 1件: Adrenergic signaling in cardiomyocytes D05775 Rufinamide 1件: 144
144 SCN5A 1件: Adrenergic signaling in cardiomyocytes D07552 Bupivacaine 8件: 46, 51, 53, 70, 96, 168, 226, 298
145 SCN5A 1件: Adrenergic signaling in cardiomyocytes D07962 Flecainide 1件: 6
146 SCN5A 1件: Adrenergic signaling in cardiomyocytes D08116 Levobupivacaine 1件: 46
147 SCN5A 1件: Adrenergic signaling in cardiomyocytes D08127 Lidocaine 13件: 6, 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256
148 SCN5A 1件: Adrenergic signaling in cardiomyocytes D08215 Mexiletine 5件: 1, 2, 10, 113, 114
149 SCN5A 1件: Adrenergic signaling in cardiomyocytes D08319 Oxybuprocaine 1件: 6
150 SCN5A 1件: Adrenergic signaling in cardiomyocytes D08458 Quinidine 3件: 2, 8, 13
151 SCN5A 1件: Adrenergic signaling in cardiomyocytes D08490 Ropivacaine 3件: 36, 46, 70
152 SCN5A 1件: Adrenergic signaling in cardiomyocytes D11155 Eleclazine 1件: 58
153 SCN9A 1件: Taste transduction D00252 Carbamazepine 2件: 13, 231
154 SCN9A 1件: Taste transduction D00354 Lamotrigine 5件: 13, 34, 38, 114, 144
155 SCN9A 1件: Taste transduction D00358 Lidocaine 13件: 6, 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256
156 SCN9A 1件: Taste transduction D00512 Phenytoin 1件: 13
157 SCN9A 1件: Taste transduction D00533 Oxcarbazepine 1件: 13
158 SCN9A 1件: Taste transduction D00537 Topiramate 6件: 6, 97, 140, 144, 156, 193
159 SCN9A 1件: Taste transduction D00538 Zonisamide 1件: 6
160 SCN9A 1件: Taste transduction D00636 Amiodarone 2件: 28, 127
161 SCN9A 1件: Taste transduction D00638 Flecainide 1件: 6
162 SCN9A 1件: Taste transduction D00639 Mexiletine 5件: 1, 2, 10, 113, 114
163 SCN9A 1件: Taste transduction D00642 Quinidine 3件: 2, 8, 13
164 SCN9A 1件: Taste transduction D00643 Quinidine 3件: 2, 8, 13
165 SCN9A 1件: Taste transduction D01287 Levobupivacaine 1件: 46
166 SCN9A 1件: Taste transduction D01450 Bupivacaine 8件: 46, 51, 53, 70, 96, 168, 226, 298
167 SCN9A 1件: Taste transduction D01768 Oxybuprocaine 1件: 6
168 SCN9A 1件: Taste transduction D02086 Lidocaine 13件: 6, 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256
169 SCN9A 1件: Taste transduction D02103 Phenytoin 1件: 13
170 SCN9A 1件: Taste transduction D02272 Quinidine 3件: 2, 8, 13
171 SCN9A 1件: Taste transduction D02910 Amiodarone 2件: 28, 127
172 SCN9A 1件: Taste transduction D03492 Cibenzoline 1件: 58
173 SCN9A 1件: Taste transduction D04048 Ropivacaine 3件: 36, 46, 70
174 SCN9A 1件: Taste transduction D05775 Rufinamide 1件: 144
175 SCN9A 1件: Taste transduction D07299 Lacosamide 3件: 2, 46, 149
176 SCN9A 1件: Taste transduction D07552 Bupivacaine 8件: 46, 51, 53, 70, 96, 168, 226, 298
177 SCN9A 1件: Taste transduction D07962 Flecainide 1件: 6
178 SCN9A 1件: Taste transduction D08116 Levobupivacaine 1件: 46
179 SCN9A 1件: Taste transduction D08127 Lidocaine 13件: 6, 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256
180 SCN9A 1件: Taste transduction D08215 Mexiletine 5件: 1, 2, 10, 113, 114
181 SCN9A 1件: Taste transduction D08319 Oxybuprocaine 1件: 6
182 SCN9A 1件: Taste transduction D08458 Quinidine 3件: 2, 8, 13
183 SCN9A 1件: Taste transduction D08490 Ropivacaine 3件: 36, 46, 70
184 SCN9A 1件: Taste transduction D11155 Eleclazine 1件: 58
185 SCNN1A 2件: Taste transduction, Aldosterone-regulated sodium reabsorption D00649 Amiloride 4件: 13, 67, 225, 299
186 SCNN1A 2件: Taste transduction, Aldosterone-regulated sodium reabsorption D07447 Amiloride 4件: 13, 67, 225, 299
187 SCNN1B 2件: Taste transduction, Aldosterone-regulated sodium reabsorption D00649 Amiloride 4件: 13, 67, 225, 299
188 SCNN1B 2件: Taste transduction, Aldosterone-regulated sodium reabsorption D07447 Amiloride 4件: 13, 67, 225, 299
189 SCNN1G 2件: Taste transduction, Aldosterone-regulated sodium reabsorption D00649 Amiloride 4件: 13, 67, 225, 299
190 SCNN1G 2件: Taste transduction, Aldosterone-regulated sodium reabsorption D07447 Amiloride 4件: 13, 67, 225, 299
191 SLC5A2 - D08897 Dapagliflozin 2件: 49, 222
192 SLC5A2 - D10459 Empagliflozin 5件: 65, 72, 96, 97, 257
193 SLC6A1 2件: Synaptic vesicle cycle, GABAergic synapse D00332 Gabapentin 5件: 6, 13, 19, 70, 298
194 SLC6A2 1件: Synaptic vesicle cycle D00228 Amoxapine 1件: 46
195 SLC6A2 1件: Synaptic vesicle cycle D00809 Amitriptyline 4件: 78, 97, 226, 299
196 SLC6A2 1件: Synaptic vesicle cycle D00812 Desipramine 2件: 120, 156
197 SLC6A2 1件: Synaptic vesicle cycle D00814 Doxepin 1件: 6
198 SLC6A2 1件: Synaptic vesicle cycle D00816 Nortriptyline 2件: 6, 226
199 SLC6A2 1件: Synaptic vesicle cycle D00817 Bupropion 5件: 8, 18, 21, 96, 171
200 SLC6A2 1件: Synaptic vesicle cycle D00821 Venlafaxine 3件: 6, 13, 46
201 SLC6A2 1件: Synaptic vesicle cycle D01179 Duloxetine 2件: 6, 13
202 SLC6A2 1件: Synaptic vesicle cycle D01296 Methylphenidate 7件: 6, 13, 34, 84, 113, 179, 206
203 SLC6A2 1件: Synaptic vesicle cycle D02574 Atomoxetine 4件: 6, 8, 13, 17
204 SLC6A2 1件: Synaptic vesicle cycle D04999 Methylphenidate 7件: 6, 13, 34, 84, 113, 179, 206
205 SLC6A2 1件: Synaptic vesicle cycle D05458 Phentermine 1件: 97
206 SLC6A2 1件: Synaptic vesicle cycle D05459 Phentermine 1件: 97
207 SLC6A2 1件: Synaptic vesicle cycle D07448 Amitriptyline 4件: 78, 97, 226, 299
208 SLC6A2 1件: Synaptic vesicle cycle D07473 Atomoxetine 4件: 6, 8, 13, 17
209 SLC6A2 1件: Synaptic vesicle cycle D07591 Bupropion 5件: 8, 18, 21, 96, 171
210 SLC6A2 1件: Synaptic vesicle cycle D07791 Desipramine 2件: 120, 156
211 SLC6A2 1件: Synaptic vesicle cycle D07875 Doxepin 1件: 6
212 SLC6A2 1件: Synaptic vesicle cycle D07880 Duloxetine 2件: 6, 13
213 SLC6A2 1件: Synaptic vesicle cycle D07938 Bupropion 5件: 8, 18, 21, 96, 171
214 SLC6A2 1件: Synaptic vesicle cycle D08130 Lisdexamfetamine 1件: 13
215 SLC6A2 1件: Synaptic vesicle cycle D08222 Milnacipran 2件: 46, 49
216 SLC6A2 1件: Synaptic vesicle cycle D08288 Nortriptyline 2件: 6, 226
217 SLC6A2 1件: Synaptic vesicle cycle D08670 Venlafaxine 3件: 6, 13, 46
218 SLC6A2 1件: Synaptic vesicle cycle D11688 Ampreloxetine 2件: 6, 17
219 SLC6A3 7件: Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism D00817 Bupropion 5件: 8, 18, 21, 96, 171
220 SLC6A3 7件: Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism D01296 Methylphenidate 7件: 6, 13, 34, 84, 113, 179, 206
221 SLC6A3 7件: Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism D03215 Armodafinil 3件: 6, 13, 84
222 SLC6A3 7件: Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism D04999 Methylphenidate 7件: 6, 13, 34, 84, 113, 179, 206
223 SLC6A3 7件: Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism D05458 Phentermine 1件: 97
224 SLC6A3 7件: Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism D05459 Phentermine 1件: 97
225 SLC6A3 7件: Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism D07591 Bupropion 5件: 8, 18, 21, 96, 171
226 SLC6A3 7件: Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism D07938 Bupropion 5件: 8, 18, 21, 96, 171
227 SLC6A3 7件: Synaptic vesicle cycle, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Amphetamine addiction, Alcoholism D08130 Lisdexamfetamine 1件: 13
228 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D00228 Amoxapine 1件: 46
229 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D00326 Fluoxetine 6件: 13, 17, 78, 86, 179, 206
230 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D00809 Amitriptyline 4件: 78, 97, 226, 299
231 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D00812 Desipramine 2件: 120, 156
232 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D00814 Doxepin 1件: 6
233 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D00816 Nortriptyline 2件: 6, 226
234 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D00820 Trazodone 1件: 2
235 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D00821 Venlafaxine 3件: 6, 13, 46
236 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D00822 Citalopram 7件: 6, 8, 13, 18, 46, 98, 127
237 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D00823 Fluoxetine 6件: 13, 17, 78, 86, 179, 206
238 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D00825 Sertraline 2件: 6, 206
239 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D01179 Duloxetine 2件: 6, 13
240 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D02260 Paroxetine 4件: 6, 13, 46, 85
241 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D02360 Sertraline 2件: 6, 206
242 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D02362 Paroxetine 4件: 6, 13, 46, 85
243 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D02567 Escitalopram 3件: 2, 6, 13
244 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D05374 Paroxetine 4件: 6, 13, 46, 85
245 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D05375 Paroxetine 4件: 6, 13, 46, 85
246 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D05458 Phentermine 1件: 97
247 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D05459 Phentermine 1件: 97
248 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D07448 Amitriptyline 4件: 78, 97, 226, 299
249 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D07704 Citalopram 7件: 6, 8, 13, 18, 46, 98, 127
250 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D07704 Escitalopram 3件: 2, 6, 13
251 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D07791 Desipramine 2件: 120, 156
252 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D07875 Doxepin 1件: 6
253 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D07880 Duloxetine 2件: 6, 13
254 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D07913 Escitalopram 3件: 2, 6, 13
255 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D07945 Fenfluramine 4件: 140, 144, 145, 149
256 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D08222 Milnacipran 2件: 46, 49
257 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D08288 Nortriptyline 2件: 6, 226
258 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D08626 Trazodone 1件: 2
259 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D08670 Venlafaxine 3件: 6, 13, 46
260 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D10184 Vortioxetine 1件: 6
261 SLC6A4 2件: Synaptic vesicle cycle, Serotonergic synapse D11688 Ampreloxetine 2件: 6, 17
262 SLC10A1 2件: Bile secretion, Hepatitis B D10951 Maralixibat 3件: 296, 297, 338
263 SLC10A2 1件: Bile secretion D10796 Elobixibat 1件: 6
264 SLC10A2 1件: Bile secretion D10951 Maralixibat 3件: 296, 297, 338
265 SLC10A2 1件: Bile secretion D11716 Odevixibat 3件: 296, 297, 338
266 SLC12A2 3件: Salivary secretion, Pancreatic secretion, Vibrio cholerae infection D00247 Bumetanide 2件: 6, 158
267 SLC12A2 3件: Salivary secretion, Pancreatic secretion, Vibrio cholerae infection D00331 Furosemide 1件: 6
268 SLC12A3 - D00340 Hydrochlorothiazide 4件: 13, 67, 225, 235
269 SLC12A3 - D00345 Indapamide 1件: 13
270 SLC12A3 - D00519 Chlorothiazide 1件: 225
271 SLC12A3 - D00650 Bendroflumethiazide 1件: 67
272 SLC12A3 - D03471 Chlorothiazide 1件: 225
273 SLC12A3 - D06401 Indapamide 1件: 13
274 SLC18A2 7件: Synaptic vesicle cycle, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism D08575 Tetrabenazine 1件: 8
275 SLC18A2 7件: Synaptic vesicle cycle, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism D10675 Valbenazine 1件: 8
276 SLC18A2 7件: Synaptic vesicle cycle, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism D10701 Deutetrabenazine 1件: 8
277 SMN1 - D11559 Onasemnogene abeparvovec 1件: 3
278 SMN2 - D10881 Nusinersen 1件: 3
279 SMN2 1件: Nucleocytoplasmic transport D11406 Risdiplam 1件: 3
280 SMO 5件: Hedgehog signaling pathway, Axon guidance, Pathways in cancer, Proteoglycans in cancer, Basal cell carcinoma D09992 Vismodegib 1件: 85
281 SMO 5件: Hedgehog signaling pathway, Axon guidance, Pathways in cancer, Proteoglycans in cancer, Basal cell carcinoma D10671 Taladegib 1件: 85
282 SMPD1 5件: Sphingolipid metabolism, Metabolic pathways, Sphingolipid signaling pathway, Lysosome, Necroptosis D10820 Olipudase alfa 1件: 19
283 SNAP25 2件: Synaptic vesicle cycle, Insulin secretion D00783 Botulinum toxin type A 13件: 2, 5, 6, 7, 13, 15, 17, 36, 51, 70, 113, 149, 226
284 SNAP25 2件: Synaptic vesicle cycle, Insulin secretion D02735 Botulinum toxin type B 4件: 2, 6, 13, 51
285 SNCA 3件: Alzheimer disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases D11420 Prasinezumab 1件: 6
286 SOD1 8件: Peroxisome, Longevity regulating pathway - multiple species, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Chemical carcinogenesis - reactive oxygen species D11811 Tofersen 1件: 2
287 SRC 42件: EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Rap1 signaling pathway, Chemokine signaling pathway, Mitophagy - animal, Endocytosis, Axon guidance, VEGF signaling pathway, Focal adhesion, Adherens junction, Tight junction, Gap junction, Platelet activation, Neutrophil extracellular trap formation, C-type lectin receptor signaling pathway, GABAergic synapse, Inflammatory mediator regulation of TRP channels, Regulation of actin cytoskeleton, GnRH signaling pathway, Estrogen signaling pathway, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Bacterial invasion of epithelial cells, Epithelial cell signaling in Helicobacter pylori infection, Pathogenic Escherichia coli infection, Shigellosis, Yersinia infection, Tuberculosis, Hepatitis B, Human cytomegalovirus infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Viral carcinogenesis, Proteoglycans in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Bladder cancer, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis D03252 Bosutinib 2件: 2, 67
288 SRC 42件: EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Rap1 signaling pathway, Chemokine signaling pathway, Mitophagy - animal, Endocytosis, Axon guidance, VEGF signaling pathway, Focal adhesion, Adherens junction, Tight junction, Gap junction, Platelet activation, Neutrophil extracellular trap formation, C-type lectin receptor signaling pathway, GABAergic synapse, Inflammatory mediator regulation of TRP channels, Regulation of actin cytoskeleton, GnRH signaling pathway, Estrogen signaling pathway, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Bacterial invasion of epithelial cells, Epithelial cell signaling in Helicobacter pylori infection, Pathogenic Escherichia coli infection, Shigellosis, Yersinia infection, Tuberculosis, Hepatitis B, Human cytomegalovirus infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Viral carcinogenesis, Proteoglycans in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Bladder cancer, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis D03658 Dasatinib 2件: 51, 85
289 SRC 42件: EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Rap1 signaling pathway, Chemokine signaling pathway, Mitophagy - animal, Endocytosis, Axon guidance, VEGF signaling pathway, Focal adhesion, Adherens junction, Tight junction, Gap junction, Platelet activation, Neutrophil extracellular trap formation, C-type lectin receptor signaling pathway, GABAergic synapse, Inflammatory mediator regulation of TRP channels, Regulation of actin cytoskeleton, GnRH signaling pathway, Estrogen signaling pathway, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Bacterial invasion of epithelial cells, Epithelial cell signaling in Helicobacter pylori infection, Pathogenic Escherichia coli infection, Shigellosis, Yersinia infection, Tuberculosis, Hepatitis B, Human cytomegalovirus infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Viral carcinogenesis, Proteoglycans in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Bladder cancer, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis D06414 Dasatinib 2件: 51, 85
290 SRC 42件: EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Rap1 signaling pathway, Chemokine signaling pathway, Mitophagy - animal, Endocytosis, Axon guidance, VEGF signaling pathway, Focal adhesion, Adherens junction, Tight junction, Gap junction, Platelet activation, Neutrophil extracellular trap formation, C-type lectin receptor signaling pathway, GABAergic synapse, Inflammatory mediator regulation of TRP channels, Regulation of actin cytoskeleton, GnRH signaling pathway, Estrogen signaling pathway, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Bacterial invasion of epithelial cells, Epithelial cell signaling in Helicobacter pylori infection, Pathogenic Escherichia coli infection, Shigellosis, Yersinia infection, Tuberculosis, Hepatitis B, Human cytomegalovirus infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Viral carcinogenesis, Proteoglycans in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Bladder cancer, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis D09664 Saracatinib 3件: 6, 89, 272
291 SRD5A1 2件: Steroid hormone biosynthesis, Metabolic pathways D03820 Dutasteride 2件: 1, 2
292 SRD5A2 3件: Steroid hormone biosynthesis, Metabolic pathways, Prostate cancer D00321 Finasteride 1件: 6
293 SRD5A2 3件: Steroid hormone biosynthesis, Metabolic pathways, Prostate cancer D03820 Dutasteride 2件: 1, 2
294 SSTR1 3件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action D07431 Somatostatin 2件: 67, 78
295 SSTR1 3件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action D10147 Pasireotide 3件: 67, 74, 75
296 SSTR2 4件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action, Gastric acid secretion D00442 Octreotide 7件: 67, 75, 84, 85, 89, 193, 227
297 SSTR2 4件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action, Gastric acid secretion D06495 Octreotide 7件: 67, 75, 84, 85, 89, 193, 227
298 SSTR2 4件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action, Gastric acid secretion D07431 Somatostatin 2件: 67, 78
299 SSTR2 4件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action, Gastric acid secretion D10147 Pasireotide 3件: 67, 74, 75
300 SSTR3 2件: Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action D07431 Somatostatin 2件: 67, 78
301 SSTR3 2件: Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action D10147 Pasireotide 3件: 67, 74, 75
302 SSTR4 1件: Neuroactive ligand-receptor interaction D07431 Somatostatin 2件: 67, 78
303 SSTR5 3件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action D07431 Somatostatin 2件: 67, 78
304 SSTR5 3件: cAMP signaling pathway, Neuroactive ligand-receptor interaction, Growth hormone synthesis, secretion and action D10147 Pasireotide 3件: 67, 74, 75
305 SYK 17件: NF-kappa B signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Osteoclast differentiation, Platelet activation, Neutrophil extracellular trap formation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Tuberculosis, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Coronavirus disease - COVID-19, Viral carcinogenesis D09347 Fostamatinib 4件: 46, 49, 61, 66
306 S1PR4 3件: FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D10930 Etrasimod 3件: 96, 97, 98
307 S1PR4 3件: FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D10968 Ozanimod 3件: 13, 96, 97
308 S1PR2 2件: Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D10930 Etrasimod 3件: 96, 97, 98
309 S1PR2 2件: Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction D10968 Ozanimod 3件: 13, 96, 97
310 SV2B 1件: ECM-receptor interaction D11842 Padsevonil 1件: 149
311 SV2A 1件: ECM-receptor interaction D00709 Levetiracetam 5件: 2, 4, 6, 13, 307
312 SV2A 1件: ECM-receptor interaction D08879 Brivaracetam 2件: 149, 309
313 SV2A 1件: ECM-receptor interaction D11842 Padsevonil 1件: 149