Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 CPT1C 1件: Thermogenesis D05442 Perhexiline 2件: 58, 272
2 CPT1C 1件: Thermogenesis D08340 Perhexiline 2件: 58, 272
3 CNR1 1件: Thermogenesis D00306 Dronabinol 8件: 2, 8, 13, 36, 46, 96, 271, 298
4 CNR1 1件: Thermogenesis D05099 Nabilone 2件: 6, 13
5 CNR1 1件: Thermogenesis D05731 Rimonabant 1件: 193
6 CNR1 1件: Thermogenesis D10915 Cannabidiol 19件: 2, 6, 8, 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271
7 CPT1A 1件: Thermogenesis D05442 Perhexiline 2件: 58, 272
8 CPT1A 1件: Thermogenesis D08340 Perhexiline 2件: 58, 272
9 CPT1B 1件: Thermogenesis D05442 Perhexiline 2件: 58, 272
10 CPT1B 1件: Thermogenesis D08340 Perhexiline 2件: 58, 272
11 CPT2 1件: Thermogenesis D05442 Perhexiline 2件: 58, 272
12 CPT2 1件: Thermogenesis D08340 Perhexiline 2件: 58, 272
13 MAPK14 7件: VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Thermogenesis, Yersinia infection, Toxoplasmosis, Tuberculosis D09639 Losmapimod 2件: 113, 222
14 MAPK14 7件: VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Thermogenesis, Yersinia infection, Toxoplasmosis, Tuberculosis D10959 Neflamapimod 1件: 8
15 ADRB3 1件: Thermogenesis D00076 Norepinephrine 1件: 22
16 ADRB3 1件: Thermogenesis D00095 Epinephrine 3件: 46, 70, 96
17 ADRB3 1件: Thermogenesis D00124 Ephedrine 1件: 11
18 ADRB3 1件: Thermogenesis D00483 Propranolol 7件: 6, 158, 167, 215, 227, 278, 296
19 ADRB3 1件: Thermogenesis D00485 Pseudoephedrine 1件: 17
20 ADRB3 1件: Thermogenesis D00996 Epinephrine 3件: 46, 70, 96
21 ADRB3 1件: Thermogenesis D01277 Droxidopa 5件: 5, 6, 17, 169, 170
22 ADRB3 1件: Thermogenesis D02149 Epinephrine 3件: 46, 70, 96
23 ADRB3 1件: Thermogenesis D02349 Dipivefrin 1件: 6
24 ADRB3 1件: Thermogenesis D05206 Norepinephrine 1件: 22
25 ADRB3 1件: Thermogenesis D05648 Pseudoephedrine 1件: 17
26 ADRB3 1件: Thermogenesis D05649 Pseudoephedrine 1件: 17
27 ADRB3 1件: Thermogenesis D08443 Propranolol 7件: 6, 158, 167, 215, 227, 278, 296
28 ADRB3 1件: Thermogenesis D08449 Pseudoephedrine 1件: 17
29 ADRB3 1件: Thermogenesis D09535 Mirabegron 4件: 6, 13, 53, 226
30 FGFR1 1件: Thermogenesis D10481 Nintedanib 5件: 51, 85, 89, 227, 228
31 FGFR1 1件: Thermogenesis D11589 Infigratinib 1件: 276
32 MTOR 3件: Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus D00753 Sirolimus 41件: 2, 6, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
33 MTOR 3件: Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus D02714 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277
34 MTOR 3件: Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus D06068 Temsirolimus 4件: 13, 34, 89, 331
35 MAP3K5 3件: Tight junction, TNF signaling pathway, Thermogenesis D10988 Selonsertib 1件: 86
36 NPR1 2件: Vascular smooth muscle contraction, Thermogenesis D04051 Erythrityl tetranitrate 1件: 46
37 NPR1 2件: Vascular smooth muscle contraction, Thermogenesis D05147 Nesiritide 2件: 46, 58
38 PPARG 3件: Thermogenesis, Transcriptional misregulation in cancer, Thyroid cancer D00596 Rosiglitazone 5件: 46, 75, 97, 222, 265
39 PPARG 3件: Thermogenesis, Transcriptional misregulation in cancer, Thyroid cancer D00945 Pioglitazone 17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
40 PPARG 3件: Thermogenesis, Transcriptional misregulation in cancer, Thyroid cancer D08378 Pioglitazone 17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
41 PPARG 3件: Thermogenesis, Transcriptional misregulation in cancer, Thyroid cancer D08491 Rosiglitazone 5件: 46, 75, 97, 222, 265
42 PPARG 3件: Thermogenesis, Transcriptional misregulation in cancer, Thyroid cancer D11256 Seladelpar 2件: 93, 94
43 PPARG 3件: Thermogenesis, Transcriptional misregulation in cancer, Thyroid cancer D11603 Leriglitazone 1件: 20
44 PRKAA1 2件: Tight junction, Thermogenesis D00944 Metformin 24件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
45 PRKAA1 2件: Tight junction, Thermogenesis D04966 Metformin 24件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
46 PRKAA2 2件: Tight junction, Thermogenesis D00944 Metformin 24件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
47 PRKAA2 2件: Tight junction, Thermogenesis D04966 Metformin 24件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
48 MAPK11 7件: VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Thermogenesis, Yersinia infection, Toxoplasmosis, Tuberculosis D09639 Losmapimod 2件: 113, 222
49 MAPK11 7件: VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Thermogenesis, Yersinia infection, Toxoplasmosis, Tuberculosis D10959 Neflamapimod 1件: 8
50 MAPK13 7件: VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Thermogenesis, Yersinia infection, Toxoplasmosis, Tuberculosis D09639 Losmapimod 2件: 113, 222
51 MAPK13 7件: VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Thermogenesis, Yersinia infection, Toxoplasmosis, Tuberculosis D10959 Neflamapimod 1件: 8
52 MAPK12 7件: VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Thermogenesis, Yersinia infection, Toxoplasmosis, Tuberculosis D09639 Losmapimod 2件: 113, 222
53 MAPK12 7件: VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Thermogenesis, Yersinia infection, Toxoplasmosis, Tuberculosis D10959 Neflamapimod 1件: 8