Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 CCR5 3件: Viral protein interaction with cytokine and cytokine receptor, Toxoplasmosis, Viral carcinogenesis D06670 Maraviroc 2件: 46, 84
2 CCR5 3件: Viral protein interaction with cytokine and cytokine receptor, Toxoplasmosis, Viral carcinogenesis D09878 Cenicriviroc 1件: 94
3 MAPK14 4件: VEGF signaling pathway, Yersinia infection, Toxoplasmosis, Tuberculosis D09639 Losmapimod 2件: 113, 222
4 MAPK14 4件: VEGF signaling pathway, Yersinia infection, Toxoplasmosis, Tuberculosis D10959 Neflamapimod 1件: 8
5 ALOX5 1件: Toxoplasmosis D00414 Zileuton 3件: 85, 160, 164
6 ALOX5 1件: Toxoplasmosis D01773 Oxatomide 1件: 113
7 HLA-DMA 4件: Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
8 HLA-DMB 4件: Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
9 HLA-DOA 4件: Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
10 HLA-DOB 4件: Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
11 HLA-DPA1 4件: Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
12 HLA-DPB1 4件: Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
13 HLA-DQA1 4件: Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
14 HLA-DQA2 4件: Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
15 HLA-DQB1 4件: Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
16 HLA-DRA 4件: Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
17 HLA-DRB1 4件: Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
18 HLA-DRB3 4件: Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
19 HLA-DRB4 4件: Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
20 HLA-DRB5 4件: Type I diabetes mellitus, Toxoplasmosis, Tuberculosis, Viral myocarditis D04318 Glatiramer 4件: 2, 13, 96, 156
21 IFNG 3件: Type I diabetes mellitus, Toxoplasmosis, Tuberculosis D04242 Fontolizumab 1件: 46
22 IFNG 3件: Type I diabetes mellitus, Toxoplasmosis, Tuberculosis D11120 Emapalumab 2件: 49, 107
23 IFNGR1 2件: Toxoplasmosis, Tuberculosis D00747 Interferon gamma-1b 7件: 18, 65, 85, 228, 299, 301, 326
24 IFNGR2 2件: Toxoplasmosis, Tuberculosis D00747 Interferon gamma-1b 7件: 18, 65, 85, 228, 299, 301, 326
25 IL10 4件: Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, Toxoplasmosis, Tuberculosis D01583 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
26 IL12A 3件: Type I diabetes mellitus, Toxoplasmosis, Tuberculosis D09214 Ustekinumab 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271
27 IL12B 3件: Type I diabetes mellitus, Toxoplasmosis, Tuberculosis D09214 Ustekinumab 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271
28 JAK1 3件: Toxoplasmosis, Tuberculosis, Viral carcinogenesis D09959 Ruxolitinib 1件: 228
29 JAK1 3件: Toxoplasmosis, Tuberculosis, Viral carcinogenesis D09970 Tofacitinib 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271
30 JAK1 3件: Toxoplasmosis, Tuberculosis, Viral carcinogenesis D10308 Baricitinib 13件: 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325
31 JAK1 3件: Toxoplasmosis, Tuberculosis, Viral carcinogenesis D10653 Peficitinib 1件: 46
32 JAK1 3件: Toxoplasmosis, Tuberculosis, Viral carcinogenesis D10871 Filgotinib 6件: 46, 53, 96, 97, 222, 271
33 JAK1 3件: Toxoplasmosis, Tuberculosis, Viral carcinogenesis D10944 Itacitinib 5件: 46, 51, 60, 97, 228
34 JAK1 3件: Toxoplasmosis, Tuberculosis, Viral carcinogenesis D10994 Upadacitinib 8件: 40, 41, 46, 49, 96, 97, 107, 271
35 JAK2 2件: Toxoplasmosis, Tuberculosis D09959 Ruxolitinib 1件: 228
36 JAK2 2件: Toxoplasmosis, Tuberculosis D09970 Tofacitinib 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271
37 JAK2 2件: Toxoplasmosis, Tuberculosis D10308 Baricitinib 13件: 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325
38 JAK2 2件: Toxoplasmosis, Tuberculosis D10653 Peficitinib 1件: 46
39 NFKB1 5件: Yersinia infection, Toxoplasmosis, Tuberculosis, Transcriptional misregulation in cancer, Viral carcinogenesis D01146 Iguratimod 4件: 46, 51, 53, 271
40 MAPK11 4件: VEGF signaling pathway, Yersinia infection, Toxoplasmosis, Tuberculosis D09639 Losmapimod 2件: 113, 222
41 MAPK11 4件: VEGF signaling pathway, Yersinia infection, Toxoplasmosis, Tuberculosis D10959 Neflamapimod 1件: 8
42 MAPK13 4件: VEGF signaling pathway, Yersinia infection, Toxoplasmosis, Tuberculosis D09639 Losmapimod 2件: 113, 222
43 MAPK13 4件: VEGF signaling pathway, Yersinia infection, Toxoplasmosis, Tuberculosis D10959 Neflamapimod 1件: 8
44 BCL2 2件: Toxoplasmosis, Tuberculosis D10679 Venetoclax 1件: 28
45 RELA 5件: Yersinia infection, Toxoplasmosis, Tuberculosis, Transcriptional misregulation in cancer, Viral carcinogenesis D12181 Edasalonexent 1件: 113
46 MAPK12 4件: VEGF signaling pathway, Yersinia infection, Toxoplasmosis, Tuberculosis D09639 Losmapimod 2件: 113, 222
47 MAPK12 4件: VEGF signaling pathway, Yersinia infection, Toxoplasmosis, Tuberculosis D10959 Neflamapimod 1件: 8
48 TGFB1 2件: Toxoplasmosis, Tuberculosis D09620 Fresolimumab 4件: 51, 85, 222, 274
49 TGFB2 2件: Toxoplasmosis, Tuberculosis D09620 Fresolimumab 4件: 51, 85, 222, 274
50 TGFB3 2件: Toxoplasmosis, Tuberculosis D09620 Fresolimumab 4件: 51, 85, 222, 274
51 TNF 6件: Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis D00742 Etanercept 17件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298
52 TNF 6件: Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis D00754 Thalidomide 20件: 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331
53 TNF 6件: Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis D01583 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
54 TNF 6件: Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis D02597 Adalimumab 18件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271
55 TNF 6件: Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis D02598 Infliximab 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271
56 TNF 6件: Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis D03441 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271
57 TNF 6件: Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis D04358 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271
58 TNF 6件: Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis D04687 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331
59 TNF 6件: Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis D05393 Pegsunercept 1件: 46
60 TNF 6件: Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis D08976 Pomalidomide 6件: 28, 34, 51, 85, 227, 331
61 TNF 6件: Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Type I diabetes mellitus, Yersinia infection, Toxoplasmosis, Tuberculosis D09944 Ozoralizumab 1件: 46
62 TYK2 1件: Toxoplasmosis D09970 Tofacitinib 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271
63 TYK2 1件: Toxoplasmosis D11817 Deucravacitinib 2件: 96, 97
64 CASP9 4件: VEGF signaling pathway, Toxoplasmosis, Tuberculosis, Viral myocarditis D11195 Rimiducid 6件: 19, 60, 65, 284, 285, 326
65 CD40 3件: Toxoplasmosis, Transcriptional misregulation in cancer, Viral myocarditis D11357 Bleselumab 1件: 222
66 CD40 3件: Toxoplasmosis, Transcriptional misregulation in cancer, Viral myocarditis D11597 Ravagalimab 2件: 53, 97
67 CD40 3件: Toxoplasmosis, Transcriptional misregulation in cancer, Viral myocarditis D11610 Iscalimab 2件: 49, 53
68 CD40LG 2件: Toxoplasmosis, Viral myocarditis D06193 Toralizumab 1件: 63