| 1 | 
                
                    2,2-bis(4-hydroxy-3-tert-butylphenyl)propane
                
             | [0]  | - | - | - | [5]  19 19, 86, 90, 276, 299 💬
 | 
| 2 | 
                
                    Abatacept
                
             | [2]  Abatacept Abatacept; Orencia | [1]  Abatacept 
                
                    Abatacept
                
             💬
 | [2]  CD80 CD80, CD86 💬
 | [13]  Allograft rejection Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Virion - Adenovirus 💬 | [26]  11 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
 | 
| 3 | 
                
                    Acetylcysteine
                
             | [3]  Acetylcysteine Acetylcysteine; Mucomyst; N-acetylcysteine | [1]  Acetylcysteine 
                
                    Acetylcysteine
                
             💬
 | - | - | [21]  6 6, 13, 19, 20, 21, 49, 51, 53, 58, 63, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337 💬
 | 
| 4 | 
                
                    Adalimumab
                
             | [7]  Adalimumab Adalimumab; AMGEVITA; Cyltezo; Hulio; Humira; Hyrimoz; Imraldi | [1]  Adalimumab 
                
                    Adalimumab
                
             💬
 | [1]  TNF TNF 💬
 | [67]  AGE-RAGE signaling pathway in diabetic complications AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬 | [17]  19 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
 | 
| 5 | 
                
                    Adrabetadex
                
             | [1]  Adrabetadex Adrabetadex | - | - | - | [1]  19 19 💬
 | 
| 6 | 
                
                    Afegostat
                
             | [1]  Afegostat Afegostat | [1]  Afegostat 
                
                    Afegostat
                
             💬
 | - | - | [1]  19 19 💬
 | 
| 7 | 
                
                    Agalsidase alfa
                
             | [5]  AGALSIDASE ALFA AGALSIDASE ALFA; Agalsidase Alpha; Alpha-galactosidase A; Recombinant alpha-galactosidase A; REPLAGAL | [1]  Agalsidase alfa 
                
                    Agalsidase alfa
                
             💬
 | [1]  GLA GLA 💬
 | [6]  Galactose metabolism Galactose metabolism, Glycerolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series, Lysosome, Metabolic pathways, Sphingolipid metabolism 💬 | [1]  19 19 💬
 | 
| 8 | 
                
                    Agalsidase beta
                
             | [2]  AGALSIDASE BETA AGALSIDASE BETA; FABRAZYME | [1]  Agalsidase beta 
                
                    Agalsidase beta
                
             💬
 | [1]  GLA GLA 💬
 | [6]  Galactose metabolism Galactose metabolism, Glycerolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series, Lysosome, Metabolic pathways, Sphingolipid metabolism 💬 | [1]  19 19 💬
 | 
| 9 | 
                
                    Alemtuzumab
                
             | [4]  Alemtuzumab Alemtuzumab; Campath; Lemtrada; MABCAMPATH | [1]  Alemtuzumab 
                
                    Alemtuzumab
                
             💬
 | [1]  CD52 CD52 💬
 | - | [22]  13 13, 15, 19, 20, 36, 43, 44, 46, 49, 51, 60, 62, 63, 65, 85, 96, 164, 234, 283, 284, 285, 326 💬
 | 
| 10 | 
                
                    Alendronic acid
                
             | [3]  Alendronate Alendronate; Alendronate sodium; ALENDRONIC ACID | [1]  Alendronic acid 
                
                    Alendronic acid
                
             💬
 | [1]  FDPS FDPS 💬
 | [4]  Human T-cell leukemia virus 1 infection Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬 | [7]  19 19, 41, 46, 50, 271, 274, 299 💬
 | 
| 11 | 
                
                    Alglucerase
                
             | [1]  Ceredase Ceredase | [1]  Alglucerase 
                
                    Alglucerase
                
             💬
 | [1]  GBA1 GBA1 💬
 | [4]  Lysosome Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism 💬 | [1]  19 19 💬
 | 
| 12 | 
                
                    Ambroxol
                
             | [1]  Ambroxol Ambroxol | [1]  Ambroxol 
                
                    Ambroxol
                
             💬
 | - | - | [2]  6 6, 19 💬
 | 
| 13 | 
                
                    Amoxicillin
                
             | [4]  Amoxicilina Amoxicilina; AMOXICILLIN; Amoxycillin; Augmentin | [2]  Amoxicillin 
                
                    Amoxicillin
                
            , 
                
                    Amoxicillin
                
             💬
 | - | - | [9]  6 6, 19, 46, 63, 84, 96, 97, 222, 299 💬
 | 
| 14 | 
                
                    Angiotensin II
                
             | [2]  Angiotensin Angiotensin; Angiotensin II | [2]  Angiotensin II 
                
                    Angiotensin II
                
            , 
                
                    Angiotensin II
                
             💬
 | [2]  AGTR1 AGTR1, AGTR2 💬
 | [16]  AGE-RAGE signaling pathway in diabetic complications AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬 | [7]  17 17, 19, 46, 66, 86, 222, 224 💬
 | 
| 15 | 
                
                    Arimoclomol
                
             | [1]  ARIMOCLOMOL ARIMOCLOMOL | [1]  Arimoclomol 
                
                    Arimoclomol
                
             💬
 | - | - | [3]  2 2, 15, 19 💬
 | 
| 16 | 
                
                    Ataluren
                
             | [2]  ATALUREN ATALUREN; Translarna | [1]  Ataluren 
                
                    Ataluren
                
             💬
 | - | - | [6]  19 19, 113, 140, 246, 299, 329 💬
 | 
| 17 | 
                
                    Azathioprine
                
             | [3]  Azathioprine Azathioprine; Azatioprina; Imuran | [1]  Azathioprine 
                
                    Azathioprine
                
             💬
 | - | - | [21]  6 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 93, 94, 95, 96, 97, 162 💬
 | 
| 18 | 
                
                    Betadex
                
             | [1]  Beta-cyclodextrin Beta-cyclodextrin | [1]  Betadex 
                
                    Betadex
                
             💬
 | - | - | [1]  19 19 💬
 | 
| 19 | 
                
                    Betaine
                
             | [2]  Betaine Betaine; Cystadane | [1]  Betaine 
                
                    Betaine
                
             💬
 | - | - | [3]  19 19, 201, 337 💬
 | 
| 20 | 
                
                    Busulfan
                
             | [3]  Busilvex Busilvex; Busulfan; BUSULFANO | [1]  Busulfan 
                
                    Busulfan
                
             💬
 | - | - | [13]  19 19, 20, 28, 36, 49, 51, 60, 65, 164, 274, 284, 285, 326 💬
 | 
| 21 | 
                
                    Calcium
                
             | [2]  Calcio Calcio; Calcium | - | - | - | [27]  6 6, 13, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 156, 214, 215, 222, 224, 235, 265, 274, 298, 299 💬
 | 
| 22 | 
                
                    Calcium carbonate
                
             | [3]  Calcio carbonato Calcio carbonato; Calcium; Calcium carbonate | [2]  Calcium carbonate 
                
                    Calcium carbonate
                
            , 
                
                    Calcium carbonate
                
             💬
 | - | - | [9]  13 13, 19, 46, 53, 75, 96, 235, 274, 299 💬
 | 
| 23 | 
                
                    Carbonate ion
                
             | [1]  Carbonate Carbonate | - | - | - | [12]  2 2, 13, 17, 18, 19, 46, 53, 75, 96, 127, 235, 299 💬
 | 
| 24 | 
                
                    Cerliponase alfa
                
             | [2]  Brineura Brineura; Cerliponase Alfa | [1]  Cerliponase alfa 
                
                    Cerliponase alfa
                
             💬
 | [1]  TPP1 TPP1 💬
 | [1]  Lysosome Lysosome 💬 | [1]  19 19 💬
 | 
| 25 | 
                
                    Cholecalciferol
                
             | [5]  Cholecalciferol Cholecalciferol; Colecalciferol; Multivitamin; Vitamin D; Vitamin D3 | [1]  Cholecalciferol 
                
                    Cholecalciferol
                
             💬
 | [1]  VDR VDR 💬
 | [5]  Chemical carcinogenesis - receptor activation Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬 | [24]  6 6, 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
 | 
| 26 | 
                
                    Cholesterol
                
             | [1]  Cholesterol Cholesterol | [1]  Cholesterol 
                
                    Cholesterol
                
             💬
 | - | - | [6]  8 8, 19, 90, 160, 222, 310 💬
 | 
| 27 | 
                
                    Clofarabine
                
             | [1]  Clofarabine Clofarabine | [1]  Clofarabine 
                
                    Clofarabine
                
             💬
 | [3]  POLA1 POLA1, POLA2, RRM1 💬
 | [7]  DNA replication DNA replication, Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism 💬 | [5]  19 19, 20, 60, 234, 326 💬
 | 
| 28 | 
                
                    Cyclophosphamide
                
             | [6]  Ciclofosfamida Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; Cyclophosphamide; Cyclophosphamidum; Cytoxan | [2]  Cyclophosphamide 
                
                    Cyclophosphamide
                
            , 
                
                    Cyclophosphamide
                
             💬
 | - | - | [44]  11 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 274, 283, 284, 285, 288, 326, 331 💬
 | 
| 29 | 
                
                    Cyclosporine
                
             | [10]  CICLOSPORIN CICLOSPORIN; Ciclosporina; Ciclosporine; CYCLOSPORIN; Cyclosporin A; Cyclosporine; Cyclosporine A; Ikervis; NEORAL; Restasis | [1]  Cyclosporine 
                
                    Cyclosporine
                
             💬
 | [5]  PPP3CA PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
 | [33]  Alzheimer disease Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬 | [44]  11 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
 | 
| 30 | 
                
                    Cysteamine
                
             | [8]  2-aminoethanethiol 2-aminoethanethiol; Beta-Mercaptoethylamine; CYSTADROPS; CYSTAGON; Cysteamine; Mercaptamina; Mercaptamine; PROCYSBI | [1]  Cysteamine 
                
                    Cysteamine
                
             💬
 | - | - | [4]  8 8, 19, 21, 299 💬
 | 
| 31 | 
                
                    Cysteine
                
             | [2]  Cysteine Cysteine; Cysteine hydrochloride | - | - | - | [10]  13 13, 19, 34, 84, 85, 88, 90, 254, 296, 310 💬
 | 
| 32 | 
                
                    Dapagliflozin
                
             | [2]  Dapagliflozin Dapagliflozin; Forxiga | [1]  Dapagliflozin 
                
                    Dapagliflozin
                
             💬
 | [1]  SLC5A2 SLC5A2 💬
 | - | [7]  19 19, 49, 66, 67, 86, 88, 222 💬
 | 
| 33 | 
                
                    Eliglustat
                
             | [2]  Cerdelga Cerdelga; Eliglustat | [1]  Eliglustat 
                
                    Eliglustat
                
             💬
 | [1]  UGCG UGCG 💬
 | [2]  Metabolic pathways Metabolic pathways, Sphingolipid metabolism 💬 | [1]  19 19 💬
 | 
| 34 | 
                
                    Elosulfase alfa
                
             | [3]  Elosulfase alfa Elosulfase alfa; Recombinant human N-acetylgalactosamine-6-sulfatase; RhGALNS | [1]  Elosulfase alfa 
                
                    Elosulfase alfa
                
             💬
 | [1]  GALNS GALNS 💬
 | [3]  Glycosaminoglycan degradation Glycosaminoglycan degradation, Lysosome, Metabolic pathways 💬 | [1]  19 19 💬
 | 
| 35 | 
                
                    ELX-02
                
             | [1]  ELX-02 ELX-02 | - | - | - | [3]  19 19, 218, 299 💬
 | 
| 36 | 
                
                    Enalapril
                
             | [2]  ENALAPRIL ENALAPRIL; Enalapril Maleate | [1]  Enalapril 
                
                    Enalapril
                
             💬
 | [1]  ACE ACE 💬
 | [6]  Chagas disease Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬 | [6]  19 19, 46, 66, 113, 210, 222 💬
 | 
| 37 | 
                
                    Fludarabine
                
             | [4]  FLUDARA FLUDARA; FLUDARABINA; Fludarabine; Fludarabine phosphate | [1]  Fludarabine 
                
                    Fludarabine
                
             💬
 | [1]  RRM1 RRM1 💬
 | [6]  Drug metabolism - other enzymes Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism 💬 | [20]  11 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬
 | 
| 38 | 
                
                    Gabapentin
                
             | [4]  Gabapentin Gabapentin; GABAPENTINA; Gabapentine; NEURONTIN | [1]  Gabapentin 
                
                    Gabapentin
                
             💬
 | [5]  CACNA2D1 CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4, SLC6A1 💬
 | [9]  Adrenergic signaling in cardiomyocytes Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway, Synaptic vesicle cycle 💬 | [5]  6 6, 13, 19, 70, 298 💬
 | 
| 39 | 
                
                    Galsulfase
                
             | [2]  GALSULFASE GALSULFASE; Naglazyme | [1]  Galsulfase 
                
                    Galsulfase
                
             💬
 | [1]  ARSB ARSB 💬
 | [3]  Glycosaminoglycan degradation Glycosaminoglycan degradation, Lysosome, Metabolic pathways 💬 | [1]  19 19 💬
 | 
| 40 | 
                
                    Gamolenic acid
                
             | [2]  Gamma-Linolenic acid Gamma-Linolenic acid; Linolenic acid | [1]  Gamolenic acid 
                
                    Gamolenic acid
                
             💬
 | - | - | [3]  13 13, 19, 46 💬
 | 
| 41 | 
                
                    Gelatin
                
             | [3]  Gelatin Gelatin; Gelatine; Sulfur Colloid | [2]  Gelatin 
                
                    Gelatin
                
            , 
                
                    Donkey glue
                
             💬
 | - | - | [7]  19 19, 28, 62, 78, 97, 269, 299 💬
 | 
| 42 | 
                
                    Genistein
                
             | [1]  GENISTEIN GENISTEIN | [1]  Genistein 
                
                    Genistein
                
             💬
 | - | - | [2]  19 19, 299 💬
 | 
| 43 | 
                
                    Hydroxypropyl betadex
                
             | [1]  2-HYDROXYPROPYL-BETA-CYCLODEXTRIN 2-HYDROXYPROPYL-BETA-CYCLODEXTRIN | - | - | - | [1]  19 19 💬
 | 
| 44 | 
                
                    Hydroxyurea
                
             | [1]  Hydroxyurea Hydroxyurea | [1]  Hydroxyurea 
                
                    Hydroxyurea
                
             💬
 | [1]  RRM2 RRM2 💬
 | [7]  Drug metabolism - other enzymes Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway 💬 | [8]  3 3, 13, 19, 20, 65, 85, 86, 284 💬
 | 
| 45 | 
                
                    Idursulfase
                
             | [4]  Elaprase Elaprase; Iduronate 2-sulfatase; IDURSULFASA; IDURSULFASE | [1]  Idursulfase 
                
                    Idursulfase
                
             💬
 | [1]  IDS IDS 💬
 | [3]  Glycosaminoglycan degradation Glycosaminoglycan degradation, Lysosome, Metabolic pathways 💬 | [1]  19 19 💬
 | 
| 46 | 
                
                    Idursulfase beta
                
             | [3]  Hunterase Hunterase; Iduronate 2-sulfatase; Idursulfase beta | [1]  Idursulfase beta 
                
                    Idursulfase beta
                
             💬
 | [1]  IDS IDS 💬
 | [3]  Glycosaminoglycan degradation Glycosaminoglycan degradation, Lysosome, Metabolic pathways 💬 | [1]  19 19 💬
 | 
| 47 | 
                
                    Imidacloprid
                
             | [0]  | - | - | - | [5]  19 19, 20, 125, 234, 326 💬
 | 
| 48 | 
                
                    Imiglucerase
                
             | [3]  CEREZYME CEREZYME; IMIGLUCERASA; IMIGLUCERASE | [1]  Imiglucerase 
                
                    Imiglucerase
                
             💬
 | [1]  GBA1 GBA1 💬
 | [4]  Lysosome Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism 💬 | [1]  19 19 💬
 | 
| 49 | 
                
                    Insulin-like growth factor II
                
             | [0]  | - | - | - | [1]  19 19 💬
 | 
| 50 | 
                
                    Iohexol
                
             | [2]  Iohexol Iohexol; OMNIPAQUE | [1]  Iohexol 
                
                    Iohexol
                
             💬
 | - | - | [3]  19 19, 67, 222 💬
 | 
| 51 | 
                
                    L-Acetylleucine
                
             | [2]  Acetyl-l-leucine Acetyl-l-leucine; N-Acetyl-L-Leucine | - | - | - | [2]  19 19, 65 💬
 | 
| 52 | 
                
                    Laronidase
                
             | [2]  Aldurazyme Aldurazyme; LARONIDASE | [1]  Laronidase 
                
                    Laronidase
                
             💬
 | [1]  IDUA IDUA 💬
 | [3]  Glycosaminoglycan degradation Glycosaminoglycan degradation, Lysosome, Metabolic pathways 💬 | [2]  19 19, 256 💬
 | 
| 53 | 
                
                    Ledipasvir
                
             | [1]  Ledipasvir Ledipasvir | [1]  Ledipasvir 
                
                    Ledipasvir
                
             💬
 | - | - | [1]  19 19 💬
 | 
| 54 | 
                
                    Lenograstim
                
             | [2]  G-CSF G-CSF; Lenograstim | [1]  Lenograstim 
                
                    Lenograstim
                
             💬
 | [1]  CSF3R CSF3R 💬
 | [5]  Cytokine-cytokine receptor interaction Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬 | [7]  2 2, 13, 16, 18, 19, 57, 65 💬
 | 
| 55 | 
                
                    Leucine
                
             | [2]  L-leucine L-leucine; Leucine | [1]  Leucine 
                
                    Leucine
                
             💬
 | - | - | [6]  6 6, 19, 65, 283, 284, 299 💬
 | 
| 56 | 
                
                    Leucovorin
                
             | [2]  Folinic acid Folinic acid; Leucovorin | [2]  Folinic acid 
                
                    Folinic acid
                
            , 
                
                    Folinic acid calcium salt pentahydrate
                
             💬
 | - | - | [4]  19 19, 46, 107, 320 💬
 | 
| 57 | 
                
                    Levothyroxine
                
             | [2]  Levothyroxine Levothyroxine; Thyroxine | [1]  Levothyroxine 
                
                    Levothyroxine
                
             💬
 | [2]  THRA THRA, THRB 💬
 | [2]  Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬 | [5]  19 19, 49, 78, 80, 222 💬
 | 
| 58 | 
                
                    Lisinopril
                
             | [2]  LISINOPRIL LISINOPRIL; ZESTRIL | [2]  Lisinopril 
                
                    Lisinopril
                
            , 
                
                    Lisinopril
                
             💬
 | [1]  ACE ACE 💬
 | [6]  Chagas disease Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬 | [7]  19 19, 46, 49, 66, 67, 113, 222 💬
 | 
| 59 | 
                
                    Losartan
                
             | [3]  Cozaar Cozaar; Losartan; Losartan Potassium | [1]  Losartan 
                
                    Losartan
                
             💬
 | [1]  AGTR1 AGTR1 💬
 | [16]  AGE-RAGE signaling pathway in diabetic complications AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬 | [17]  17 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
 | 
| 60 | 
                
                    Lucerastat
                
             | [1]  Lucerastat Lucerastat | [1]  Lucerastat 
                
                    Lucerastat
                
             💬
 | [1]  UGCG UGCG 💬
 | [2]  Metabolic pathways Metabolic pathways, Sphingolipid metabolism 💬 | [1]  19 19 💬
 | 
| 61 | 
                
                    LY3884961
                
             | [1]  LY3884961 LY3884961 | - | - | - | [1]  19 19 💬
 | 
| 62 | 
                
                    Lysine
                
             | [1]  Lysine Lysine | [1]  Lysine 
                
                    Lysine
                
             💬
 | - | - | [5]  13 13, 19, 97, 228, 299 💬
 | 
| 63 | 
                
                    Medical Cannabis
                
             | [3]  Cannabis Cannabis; Marijuana; Medical Cannabis | - | - | - | [7]  2 2, 6, 13, 19, 90, 96, 97 💬
 | 
| 64 | 
                
                    Melphalan
                
             | [3]  Alkeran Alkeran; MELPHALAN; Melphalan Hydrochloride | [1]  Melphalan 
                
                    Melphalan
                
             💬
 | - | - | [15]  11 11, 13, 14, 19, 20, 28, 60, 62, 65, 96, 164, 234, 284, 285, 299 💬
 | 
| 65 | 
                
                    Methotrexate
                
             | [6]  Methotrexat Methotrexat; Methotrexate; METHOTREXATE SODIUM; METOJECT; METOTREXATO; Méthotrexate | [1]  Methotrexate 
                
                    Methotrexate
                
             💬
 | [2]  DHFR DHFR, DHFR2 💬
 | [5]  Antifolate resistance Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬 | [38]  11 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
 | 
| 66 | 
                
                    Methylprednisolone
                
             | [4]  Medrol Medrol; Methylprednisolon; Methylprednisolone; METHYLPREDNISOLONE ACETATE | [1]  Methylprednisolone 
                
                    Methylprednisolone
                
             💬
 | [1]  NR3C1 NR3C1 💬
 | [1]  Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction 💬 | [46]  2 2, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
 | 
| 67 | 
                
                    Migalastat
                
             | [3]  1-Deoxygalactonojirimycin 1-Deoxygalactonojirimycin; Galafold; MIGALASTAT | [1]  Migalastat 
                
                    Migalastat
                
             💬
 | - | - | [1]  19 19 💬
 | 
| 68 | 
                
                    Miglustat
                
             | [2]  MIGLUSTAT MIGLUSTAT; ZAVESCA | [1]  Miglustat 
                
                    Miglustat
                
             💬
 | [1]  UGCG UGCG 💬
 | [2]  Metabolic pathways Metabolic pathways, Sphingolipid metabolism 💬 | [3]  19 19, 256, 299 💬
 | 
| 69 | 
                
                    Mycophenolate mofetil
                
             | [3]  CellCept CellCept; Mycophenolate Mofetil; Mycophenolate mofetil TEVA | [1]  Mycophenolate mofetil 
                
                    Mycophenolate mofetil
                
             💬
 | [2]  IMPDH1 IMPDH1, IMPDH2 💬
 | [4]  Drug metabolism - other enzymes Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬 | [34]  2 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
 | 
| 70 | 
                
                    Mycophenolic acid
                
             | [5]  Acido Micofenolico Acido Micofenolico; MICOFENOLICO ACIDO; Mycophenolate; Mycophenolic acid; Myfortic | [1]  Mycophenolic acid 
                
                    Mycophenolic acid
                
             💬
 | [2]  IMPDH1 IMPDH1, IMPDH2 💬
 | [4]  Drug metabolism - other enzymes Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬 | [36]  2 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
 | 
| 71 | 
                
                    Odiparcil
                
             | [1]  Odiparcil Odiparcil | - | - | - | [1]  19 19 💬
 | 
| 72 | 
                
                    Olenasufligene relduparvovec
                
             | [1]  OLENASUFLIGENE RELDUPARVOVEC OLENASUFLIGENE RELDUPARVOVEC | - | - | - | [1]  19 19 💬
 | 
| 73 | 
                
                    Olipudase alfa
                
             | [1]  OLIPUDASE ALFA OLIPUDASE ALFA | [1]  Olipudase alfa 
                
                    Olipudase alfa
                
             💬
 | [1]  SMPD1 SMPD1 💬
 | [5]  Lysosome Lysosome, Metabolic pathways, Necroptosis, Sphingolipid metabolism, Sphingolipid signaling pathway 💬 | [1]  19 19 💬
 | 
| 74 | 
                
                    Pabinafusp alfa
                
             | [1]  Pabinafusp alfa Pabinafusp alfa | [1]  Pabinafusp alfa 
                
                    Pabinafusp alfa
                
             💬
 | [2]  IDS IDS, TFRC 💬
 | [8]  Endocytosis Endocytosis, Ferroptosis, Glycosaminoglycan degradation, HIF-1 signaling pathway, Hematopoietic cell lineage, Lysosome, Metabolic pathways, Phagosome 💬 | [1]  19 19 💬
 | 
| 75 | 
                
                    Paricalcitol
                
             | [1]  Paricalcitol Paricalcitol | [1]  Paricalcitol 
                
                    Paricalcitol
                
             💬
 | [1]  VDR VDR 💬
 | [5]  Chemical carcinogenesis - receptor activation Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬 | [5]  19 19, 66, 218, 238, 298 💬
 | 
| 76 | 
                
                    Pegunigalsidase alfa
                
             | [1]  PEGUNIGALSIDASE ALFA PEGUNIGALSIDASE ALFA | [1]  Pegunigalsidase alfa 
                
                    Pegunigalsidase alfa
                
             💬
 | - | - | [1]  19 19 💬
 | 
| 77 | 
                
                    Pentosan polysulfate
                
             | [1]  Pentosan polysulfate Pentosan polysulfate | - | - | - | [3]  19 19, 26, 226 💬
 | 
| 78 | 
                
                    Plerixafor
                
             | [2]  Mozobil Mozobil; Plerixafor | [1]  Plerixafor 
                
                    Plerixafor
                
             💬
 | [1]  CXCR4 CXCR4 💬
 | [14]  Axon guidance Axon guidance, Calcium signaling pathway, Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Intestinal immune network for IgA production, Leukocyte transendothelial migration, Pathways in cancer, Regulation of actin cytoskeleton, Viral life cycle - HIV-1, Viral protein interaction with cytokine and cytokine receptor, Virion - Human immunodeficiency virus 💬 | [5]  19 19, 20, 65, 285, 299 💬
 | 
| 79 | 
                
                    Prednisone
                
             | [3]  PREDNISONA PREDNISONA; Prednisone; RAYOS | [1]  Prednisone 
                
                    Prednisone
                
             💬
 | [1]  NR3C1 NR3C1 💬
 | [1]  Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction 💬 | [45]  2 2, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 💬
 | 
| 80 | 
                
                    Pyrimethamine
                
             | [2]  Daraprim Daraprim; Pyrimethamine | [1]  Pyrimethamine 
                
                    Pyrimethamine
                
             💬
 | - | - | [12]  2 2, 4, 6, 13, 19, 46, 51, 63, 65, 96, 97, 265 💬
 | 
| 81 | 
                
                    Quinapril
                
             | [1]  Accuretic Accuretic | [1]  Quinapril 
                
                    Quinapril
                
             💬
 | [1]  ACE ACE 💬
 | [6]  Chagas disease Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬 | [1]  19 19 💬
 | 
| 82 | 
                
                    Rebisufligene etisparvovec
                
             | [1]  Rebisufligene etisparvovec Rebisufligene etisparvovec | - | - | - | [1]  19 19 💬
 | 
| 83 | 
                
                    Rimiducid
                
             | [1]  Rimiducid Rimiducid | [1]  Rimiducid 
                
                    Rimiducid
                
             💬
 | [1]  CASP9 CASP9 💬
 | [35]  Alzheimer disease Alzheimer disease, Amyotrophic lateral sclerosis, Apoptosis, Apoptosis - multiple species, Colorectal cancer, Endometrial cancer, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Huntington disease, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Lipid and atherosclerosis, Measles, Non-small cell lung cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parkinson disease, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platinum drug resistance, Prion disease, Prostate cancer, Small cell lung cancer, Thyroid hormone signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Viral myocarditis, p53 signaling pathway 💬 | [6]  19 19, 60, 65, 284, 285, 326 💬
 | 
| 84 | 
                
                    Rituximab
                
             | [6]  MabThera MabThera; Rituxan; Rituximab; Rixathon; Ruxience; Truxima | [1]  Rituximab 
                
                    Rituximab
                
             💬
 | [1]  MS4A1 MS4A1 💬
 | [1]  Hematopoietic cell lineage Hematopoietic cell lineage 💬 | [48]  11 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
 | 
| 85 | 
                
                    Sebelipase alfa
                
             | [4]  KANUMA KANUMA; SBC-102; Sebelipasa Alfa; Sebelipase Alfa | [1]  Sebelipase alfa 
                
                    Sebelipase alfa
                
             💬
 | [1]  LIPA LIPA 💬
 | [3]  Cholesterol metabolism Cholesterol metabolism, Lysosome, Steroid biosynthesis 💬 | [1]  19 19 💬
 | 
| 86 | 
                
                    Sirolimus
                
             | [3]  Rapamune Rapamune; Rapamycin; Sirolimus | [1]  Sirolimus 
                
                    Sirolimus
                
             💬
 | [1]  MTOR MTOR 💬
 | [51]  AMPK signaling pathway AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬 | [40]  2 2, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
 | 
| 87 | 
                
                    SOBI-003
                
             | [0]  | - | - | - | [1]  19 19 💬
 | 
| 88 | 
                
                    Sofosbuvir
                
             | [1]  Sofosbuvir Sofosbuvir | [1]  Sofosbuvir 
                
                    Sofosbuvir
                
             💬
 | - | - | [1]  19 19 💬
 | 
| 89 | 
                
                    Somatotropin
                
             | [17]  Genotropin Genotropin; Growth Hormone; Human growth hormone; Humatrope; Norditropin; Norditropin SimpleXx; NUTROPIN; Nutropin AQ; NutropinAq; OMNITROPE; Recombinant human growth hormone; RhGH; SAIZEN; Somatotropin; Somatropin; SOMATROPINA; Zomacton | - | - | - | [25]  2 2, 3, 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 246, 265, 274, 276, 299, 337 💬
 | 
| 90 | 
                
                    Taliglucerase alfa
                
             | [3]  Elelyso Elelyso; PrGCD; TALIGLUCERASE ALFA | [1]  Taliglucerase alfa 
                
                    Taliglucerase alfa
                
             💬
 | [1]  GBA1 GBA1 💬
 | [4]  Lysosome Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism 💬 | [1]  19 19 💬
 | 
| 91 | 
                
                    Thiotepa
                
             | [1]  Thiotepa Thiotepa | [1]  Thiotepa 
                
                    Thiotepa
                
             💬
 | - | - | [12]  13 13, 19, 20, 28, 51, 60, 65, 85, 96, 164, 284, 285 💬
 | 
| 92 | 
                
                    Tilactase
                
             | [1]  Beta-Galactosidase Beta-Galactosidase | [1]  Lactase 
                
                    Lactase
                
             💬
 | - | - | [1]  19 19 💬
 | 
| 93 | 
                
                    Treosulfan
                
             | [2]  OVASTAT OVASTAT; Treosulfan | [1]  Treosulfan 
                
                    Treosulfan
                
             💬
 | - | - | [6]  13 13, 19, 62, 65, 283, 286 💬
 | 
| 94 | 
                
                    Velaglucerase alfa
                
             | [3]  GA-GCB GA-GCB; VELAGLUCERASE ALFA; VPRIV | [1]  Velaglucerase alfa 
                
                    Velaglucerase alfa
                
             💬
 | [1]  GBA1 GBA1 💬
 | [4]  Lysosome Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism 💬 | [1]  19 19 💬
 | 
| 95 | 
                
                    Velmanase alfa
                
             | [3]  LAMAZYM LAMAZYM; RhLAMAN; VELMANASE ALFA | [1]  Velmanase alfa 
                
                    Velmanase alfa
                
             💬
 | [1]  MAN2B1 MAN2B1 💬
 | [2]  Lysosome Lysosome, Other glycan degradation 💬 | [1]  19 19 💬
 | 
| 96 | 
                
                    Venglustat
                
             | [2]  GENZ-682452 GENZ-682452; Venglustat | [1]  Venglustat 
                
                    Venglustat
                
             💬
 | [1]  UGCG UGCG 💬
 | [2]  Metabolic pathways Metabolic pathways, Sphingolipid metabolism 💬 | [3]  6 6, 19, 67 💬
 | 
| 97 | 
                
                    Vestronidase alfa
                
             | [3]  Mepsevii Mepsevii; Recombinant human beta-glucuronidase; Vestronidase alfa | [1]  Vestronidase alfa 
                
                    Vestronidase alfa
                
             💬
 | [1]  GUSB GUSB 💬
 | [8]  Ascorbate and aldarate metabolism Ascorbate and aldarate metabolism, Biosynthesis of cofactors, Drug metabolism - other enzymes, Glycosaminoglycan degradation, Lysosome, Metabolic pathways, Pentose and glucuronate interconversions, Porphyrin metabolism 💬 | [1]  19 19 💬
 | 
| 98 | 
                
                    Vitamin D
                
             | [3]  Calciferol Calciferol; Cod liver oil; Vitamin D | - | - | - | [20]  13 13, 19, 41, 43, 44, 46, 49, 50, 68, 93, 95, 96, 97, 179, 222, 228, 235, 274, 298, 299 💬
 | 
| 99 | 
                
                    Warfarin
                
             | [2]  Warfarin Warfarin; Warfarin Sodium | [1]  Warfarin 
                
                    Warfarin
                
             💬
 | [2]  NQO1 NQO1, VKORC1 💬
 | [7]  Biosynthesis of cofactors Biosynthesis of cofactors, Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Metabolic pathways, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬 | [11]  6 6, 8, 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
 |