Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Cabergoline [3] CABERGOLINA; Cabergoline; DOSTINEX[1] D00987 [2] DRD2,
PRL 💬		[12] Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 6, 74, 75
2 Cabotegravir [1] Cabotegravir[1] D10548 --[1] 256
3 Cabozantinib [1] Cabozantinib[1] D10062 [3] AXL,
KDR,
MET 💬		[25] Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, EGFR tyrosine kinase inhibitor resistance, Epithelial cell signaling in Helicobacter pylori infection, Fluid shear stress and atherosclerosis, Focal adhesion, Gastric cancer, Hepatocellular carcinoma, MAPK signaling pathway, Malaria, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, PI3K-Akt signaling pathway, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Renal cell carcinoma, Transcriptional misregulation in cancer, VEGF signaling pathway 💬[1] 34
4 Caffeine [1] Caffeine[2] D00528 ,
D01453 		[11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 2, 6, 21, 46, 78, 96, 97, 265
5 Calcifediol [2] 25-Hydroxyvitamin D3; CALCIFEDIOL[1] D00122 [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[2] 113, 299
6 Calcipotriol [2] Calcipotriene; CALCIPOTRIOL[1] D01125 [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[2] 36, 51
7 Calcitriol [1] Calcitriol[1] D00129 [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[9] 18, 37, 46, 49, 66, 96, 158, 235, 326
8 Calcium [2] Calcio; Calcium---[27] 6, 13, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 156, 214, 215, 222, 224, 235, 265, 274, 298, 299
9 Calcium carbonate [3] Calcio carbonato; Calcium; Calcium Carbonate[2] D00932 ,
D10802 		--[9] 13, 19, 46, 53, 75, 96, 235, 274, 299
10 Calcium citrate [1] Calcium Citrate[1] D00933 --[3] 46, 84, 235
11 Calcium gluconate [1] Calcium gluconate[1] D00935 --[3] 214, 215, 235
12 Calcium lactate [1] Calcium lactate[2] D00936 ,
D02254 		--[1] 235
13 Calfactant [1] Calfactant[1] D03317 --[1] 299
14 Calusterone [0] [1] D03338 [1] AR 💬[4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[1] 2
15 Canakinumab [2] Canakinumab; Ilaris[1] D09315 [1] IL1B 💬[44] AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Alcoholic liver disease, Alzheimer disease, Amoebiasis, Antifolate resistance, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Herpes simplex virus 1 infection, Human cytomegalovirus infection, IL-17 signaling pathway, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Rheumatoid arthritis, Salmonella infection, Shigellosis, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Tuberculosis, Type I diabetes mellitus, Yersinia infection 💬[10] 46, 56, 84, 106, 107, 108, 113, 266, 267, 269
16 Candesartan [1] Candesartan[1] D00522 [1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[2] 58, 67
17 Candesartan cilexetil [1] CANDESARTAN[1] D00626 [1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 67
18 Cannabidiol [4] Cannabidiol; Epidiolex; Epidyolex; Sativex[1] D10915 [2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[20] 2, 6, 8, 13, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271
19 Cannabidivarin [1] CBDV---[1] 193
20 Cannabinol [1] CANNABINOL---[1] 36
21 CAP-1002 [1] CAP-1002---[1] 113
22 Caplacizumab [2] CABLIVI; CAPLACIZUMAB[1] D11160 [1] VWF 💬[8] Complement and coagulation cascades, Coronavirus disease - COVID-19, ECM-receptor interaction, Focal adhesion, Human papillomavirus infection, Neutrophil extracellular trap formation, PI3K-Akt signaling pathway, Platelet activation 💬[1] 64
23 Capsaicin [2] Capsaicin; Qutenza[1] D00250 [1] TRPV1 💬[2] Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[3] 6, 86, 226
24 Captopril [1] Captopril[1] D00251 [1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[8] 6, 17, 46, 86, 96, 97, 107, 271
25 Carbamazepine [1] Carbamazepine[1] D00252 [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[3] 6, 13, 231
26 Carbaspirin calcium [1] Carbasalate calcium[1] D03385 --[1] 46
27 Carbidopa [8] Carbidopa; Carbidopa-Levodopa; DUODOPA; Lodosyn; PARCOPA; SINEMET; SINEMET CR; Stalevo[1] D00558 [1] DDC 💬[9] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[7] 6, 13, 17, 90, 140, 164, 201
28 Carbomer [2] Carbomer; Lacryvisc---[1] 53
29 Carbon dioxide [1] Carbon dioxide[1] D00004 --[2] 97, 158
30 Carbon monoxide [1] Carbon Monoxide[1] D09706 --[4] 13, 53, 85, 86
31 Carbonate ion [1] Carbonate---[12] 2, 13, 17, 18, 19, 46, 53, 75, 96, 127, 235, 299
32 Carboplatin [2] Carboplatin; CBDCA[1] D01363 --[4] 28, 34, 60, 85
33 Carbopol 974P [1] Carbomer 974P---[1] 53
34 Carfilzomib [1] Carfilzomib[1] D08880 [1] PSMB5 💬[8] Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia 💬[1] 28
35 Carglumic acid [3] Carbaglu; Carglumic acid; N-Carbamylglutamate[1] D07130 [1] CPS1 💬[6] Alanine, aspartate and glutamate metabolism, Arginine biosynthesis, Biosynthesis of amino acids, Carbon metabolism, Metabolic pathways, Nitrogen metabolism 💬[3] 245, 246, 251
36 Cariprazine [1] Reagila[1] D09997 [3] DRD2,
HTR1A,
HTR2A 💬		[12] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬[1] 21
37 Carisbamate [1] Carisbamate[1] D06573 --[1] 144
38 Carmustine [1] Carmustine[1] D00254 --[5] 11, 13, 14, 28, 60
39 Carnosine [1] Carnosine---[2] 6, 13
40 Carvedilol [1] CARVEDILOL[1] D00255 [5] ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
ADRB2 💬		[13] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 57, 86, 113, 210
41 Casein [1] Casein---[1] 97
42 Casimersen [1] CASIMERSEN[1] D11988 [1] DMD 💬[4] Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Viral myocarditis 💬[1] 113
43 Caspofungin [2] Caspofungin; CASPOFUNGIN ACETATE[1] D07626 --[1] 60
44 Catridecacog [1] Catridecacog[1] D10532 --[2] 97, 288
45 Cavosonstat [1] Cavosonstat[1] D10916 --[1] 299
46 CCX-140 [0] ---[1] 222
47 CCX-354 [1] CCX-354---[1] 46
48 CDP323 [1] CDP323---[1] 13
49 CE-VST01-JC [1] CE-VST01-JC---[1] 25
50 Cediranib [1] Cediranib[1] D08881 [3] FLT1,
FLT4,
KDR 💬		[15] Breast cancer, Calcium signaling pathway, EGFR tyrosine kinase inhibitor resistance, Fluid shear stress and atherosclerosis, Focal adhesion, HIF-1 signaling pathway, MAPK signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Rheumatoid arthritis, Transcriptional misregulation in cancer, VEGF signaling pathway 💬[1] 34
51 Cefadroxil [0] [2] D00257 ,
D02353 		--[2] 222, 240
52 Cefazolin [1] Cefazolin[1] D02299 --[1] 291
53 Cefepime [1] Cefepime[1] D02376 --[2] 60, 299
54 Cefiderocol [1] Cefiderocol[1] D11302 --[1] 299
55 Cefoperazone [1] Cefoperazone[1] D07645 --[1] 296
56 Ceftaroline fosamil [1] Ceftaroline[1] D08884 --[1] 299
57 Ceftazidime [3] Ceftazidim; Ceftazidima; CEFTAZIDIME[2] D00921 ,
D07654 		--[1] 299
58 Ceftolozane [1] Ceftolozane[1] D10097 --[1] 299
59 Ceftriaxone [1] CEFTRIAXONE[1] D07659 --[4] 2, 6, 46, 97
60 Cefuroxime [2] Cefuroxim; Cefuroxime[1] D00262 --[2] 97, 299
61 Celecoxib [2] Celebrex; Celecoxib[1] D00567 [1] PTGS2 💬[22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[10] 2, 3, 34, 46, 70, 89, 107, 161, 171, 271
62 Celiprolol [1] Celiprolol[1] D07660 [1] ADRB1 💬[11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 168
63 Cemdisiran [1] CEMDISIRAN---[4] 11, 62, 66, 109
64 Cenegermin [3] Cenegermin; OXERVATE; RhNGF[1] D11028 [1] NGFR 💬[9] Apoptosis - multiple species, Cytokine-cytokine receptor interaction, MAPK signaling pathway, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Transcriptional misregulation in cancer, Virion - Lyssavirus 💬[2] 53, 90
65 Cenerimod [1] Cenerimod[1] D11283 [1] S1PR1 💬[3] FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬[1] 49
66 Cenicriviroc [1] Cenicriviroc[1] D09878 [2] CCR2,
CCR5 💬		[11] Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Toxoplasmosis, Viral carcinogenesis, Viral life cycle - HIV-1, Viral protein interaction with cytokine and cytokine receptor, Virion - Human immunodeficiency virus 💬[1] 94
67 Censavudine [1] CENSAVUDINE[1] D10550 --[2] 2, 127
68 CEP-1347 [1] CEP-1347---[1] 6
69 Cephalexin [2] CEFALEXIN; Cephalexin[2] D00263 ,
D00906 		--[1] 299
70 Cepharanthine [2] Cepharanthin; Cepharanthine[1] D01035 --[1] 53
71 Ceralifimod [1] Ceralifimod---[1] 13
72 Cerliponase alfa [2] Brineura; Cerliponase Alfa[1] D10813 [1] TPP1 💬[1] Lysosome 💬[1] 19
73 Certolizumab pegol [2] CERTOLIZUMAB PEGOL; CIMZIA[1] D03441 [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[8] 37, 46, 49, 96, 97, 107, 226, 271
74 Cetirizine [3] CETIRIZINA; Cetirizine; CETIRIZINE HYDROCHLORIDE[1] D07662 [1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[4] 13, 28, 35, 300
75 Cetrorelix [1] Cetrorelix[1] D07665 [1] GNRHR 💬[2] GnRH signaling pathway, Neuroactive ligand-receptor interaction 💬[1] 46
76 Cetuximab [2] Cetuximab; Erbitux[1] D03455 [1] EGFR 💬[48] Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease - COVID-19, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis 💬[2] 51, 86
77 Cevimeline [1] Cevimeline[1] D07667 [1] CHRM3 💬[11] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬[1] 53
78 Chamomile [2] Chamomile; MATRICARIA FLOWER[1] D09212 --[2] 6, 97
79 Chenodeoxycholic acid [3] CDCA; Chenodeoxycholic Acid; Chenodiol[1] D00163 [1] NR1H4 💬[1] Bile secretion 💬[4] 20, 96, 234, 263
80 Chicken [1] Chicken---[1] 46
81 Chlorambucil [1] Chlorambucil[1] D00266 --[1] 222
82 Chlorhexidine [2] Chlorhexidine; Chlorhexidine Gluconate[1] D07668 --[2] 86, 299
83 Chloride ion [1] Chloride---[28] 6, 11, 13, 14, 34, 41, 46, 50, 51, 53, 60, 67, 70, 96, 97, 107, 127, 168, 171, 193, 227, 228, 251, 288, 296, 297, 299, 338
84 Chlorine [1] Chlor---[2] 46, 271
85 Chlormezanone [0] [1] D00268 --[1] 13
86 Chlorogenic Acid [1] Chlorogenic Acid---[1] 97
87 Chloroquine [1] Chloroquine[1] D02366 --[3] 46, 49, 95
88 Chlorothiazide [1] Chlorothiazide[1] D00519 [1] SLC12A3 💬-[1] 225
89 Chlorpheniramine [1] Clorfenamina[1] D07398 [1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[1] 14
90 Chlorpromazine [2] Chlorpromazine; Chlorpromazine Hydrochloride[1] D00270 [13] ADRA2A,
ADRA2B,
ADRA2C,
CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5,
DRD2,
HRH1,
HTR2A,
HTR2B,
HTR2C 💬		[22] Alcoholism, Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Cocaine addiction, Dopaminergic synapse, Gap junction, Gastric acid secretion, Inflammatory mediator regulation of TRP channels, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Rap1 signaling pathway, Regulation of actin cytoskeleton, Salivary secretion, Serotonergic synapse, Taste transduction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 254
91 Cholecalciferol [5] Cholecalciferol; Colecalciferol; Multivitamin; Vitamin D; Vitamin D3[1] D00188 [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[24] 6, 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299
92 Cholesterol [1] Cholesterol[1] D00040 --[6] 8, 19, 90, 160, 222, 310
93 Cholestyramine [4] Cholestyramine; COLESTIRAMINA; COLESTYRAMINE; Questran---[3] 13, 79, 254
94 Cholic Acid [1] Cholic Acid[1] D10699 [1] NR1H4 💬[1] Bile secretion 💬[4] 20, 234, 265, 310
95 Choline [1] Choline[1] D07690 --[4] 93, 171, 193, 299
96 Chondroitin sulfate [1] Chondroitin sulfate---[2] 96, 226
97 Chromium [1] Chromium---[1] 46
98 Cibenzoline [1] Cibenzoline[1] D03492 [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[1] 58
99 Ciclesonide [1] Ciclesonide[1] D01703 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 84
100 Cicletanine [1] Cicletanine[1] D03487 --[1] 86
101 Cidofovir [1] Cidofovir[1] D00273 --[1] 25
102 Cilastatin [2] CILASTATIN; Cilastatine[1] D07698 [1] DPEP1 💬-[2] 60, 299
103 Cilazapril [1] Cilazapril[2] D01069 ,
D07699 		[1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[1] 66
104 Ciliary neurotrophic factor [1] Ciliary neurotrophic factor---[1] 90
105 Cilnidipine [1] Cilnidipine[1] D01173 [5] CACNA1B,
CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		[41] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Huntington disease, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Morphine addiction, Nicotine addiction, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Synaptic vesicle cycle, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 67
106 Cilofexor [1] Cilofexor---[2] 93, 94
107 Cilostazol [2] Cilostazol; PLETAL[1] D01896 [3] PDE3A,
PDE3B,
TBXA2R 💬		[14] Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Platelet activation, Progesterone-mediated oocyte maturation, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 46, 51, 70
108 Cimetidine [1] Cimetidine[1] D00295 [1] HRH2 💬[3] Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬[2] 2, 254
109 Cinacalcet [1] Cinacalcet[1] D03504 [1] CASR 💬[2] NOD-like receptor signaling pathway, Parathyroid hormone synthesis, secretion and action 💬[1] 238
110 Cipaglucosidase alfa [1] Cipaglucosidase Alfa[1] D11798 [1] GAA 💬[4] Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism 💬[1] 256
111 Ciprofloxacin [2] Ciprofloxacin; Ciprofloxacin hydrochloride[1] D00186 --[5] 2, 60, 96, 97, 299
112 Cisapride [1] CISAPRIDE[2] D00274 ,
D02092 		[3] HTR2A,
HTR3A,
HTR4 💬		[7] Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬[1] 13
113 Cisplatin [1] Cisplatin[1] D00275 --[1] 28
114 Citalopram [1] Citalopram[1] D07704 [1] SLC6A4 💬[2] Serotonergic synapse, Synaptic vesicle cycle 💬[7] 6, 8, 13, 18, 46, 98, 127
115 Citicoline [1] Citicolina[1] D00057 --[1] 6
116 Citric acid [1] Citric acid[1] D01222 --[2] 53, 291
117 Citrulline [1] Citrulline---[2] 86, 113
118 Cladribine [4] 2-CdA; CLADRIBINA; CLADRIBINE; MAVENCLAD[1] D01370 [1] RRM1 💬[6] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism 💬[3] 11, 13, 94
119 Clarithromycin [1] CLARITHROMYCIN[1] D00276 --[8] 6, 63, 84, 96, 97, 222, 228, 299
120 Clavulanic acid [4] AMOXICILLIN; Augmentin; Clavulanate; CLAVULANIC ACID[1] D07711 --[1] 299
121 Clazakizumab [2] BMS-945429; CLAZAKIZUMAB[1] D10312 --[2] 46, 96
122 Clemastine [2] Clemastine; CLEMASTINE FUMARATE[1] D03535 [1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[1] 13
123 Clemizole [1] Clemizole---[2] 140, 144
124 Clenbuterol [1] Clenbuterol[1] D07713 [1] ADRB2 💬[9] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[5] 1, 2, 6, 13, 256
125 Clindamycin [2] Clindamycin; Dalacin C phosphate[1] D00277 --[2] 46, 299
126 Clobazam [1] CLOBAZAM[1] D01253 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[2] 140, 144
127 Clobetasol [1] Clobetasol[1] D07715 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[4] 39, 46, 51, 162
128 Clobetasol propionate [1] Clobetasol Propionate[1] D01272 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[2] 46, 162
129 Clodronic acid [2] Bonefos; Clasteon[1] D03545 --[1] 274
130 Clofarabine [1] Clofarabine[1] D03546 [3] POLA1,
POLA2,
RRM1 💬		[7] DNA replication, Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism 💬[5] 19, 20, 60, 234, 326
131 Clofazimine [1] CLOFAZIMINE[1] D00278 --[1] 96
132 Clomifene [2] Clomiphene; Clomiphene citrate[1] D07726 [2] ESR1,
ESR2 💬		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[1] 74
133 Clonazepam [1] Clonazepam[1] D00280 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[1] 6
134 Clonidine [4] Clonidin; Clonidina; Clonidine; Clonidine hydrochloride[1] D00281 [3] ADRA2A,
ADRA2B,
ADRA2C 💬		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[4] 6, 65, 70, 78
135 Clopidogrel [1] Clopidogrel[3] D07729 ,
D10823 ,
D10824 		[1] P2RY12 💬[1] Platelet activation 💬[3] 49, 51, 86
136 Clostridium botulinum [1] Clostridium botulinum---[1] 13
137 Clostridium tetani toxoid antigen (formaldehyde inactivated) [4] Boostrix; Nimenrix; Tetanus toxoid; Tetanus toxoid adsorbed---[4] 13, 14, 46, 50
138 Clotrimazole [1] Clotrimazole[1] D00282 --[1] 97
139 Clozapine [1] CLOZAPINE[1] D00283 [11] ADRA2A,
ADRA2B,
ADRA2C,
DRD4,
HTR2A,
HTR2C,
HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E 💬		[8] Calcium signaling pathway, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction, cGMP-PKG signaling pathway 💬[1] 6
140 Coagulation factor VIIa Recombinant Human [1] RFVIIa---[1] 288
141 Coagulation factor X human [4] Coagadex; Coagulation factor X; FACTOR X; Human Coagulation FACTOR X---[1] 288
142 Cobalt [1] Cobalt---[1] 46
143 Cobalt chloride [1] Ceretec---[1] 6
144 Cobamamide [1] Cobamamide[1] D00042 --[1] 299
145 Cobimetinib [1] Cobimetinib[1] D10405 [2] MAP2K1,
MAP2K2 💬		[89] Acute myeloid leukemia, Alcoholism, Alzheimer disease, Apelin signaling pathway, Apoptosis, Autophagy - animal, B cell receptor signaling pathway, Bladder cancer, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, Colorectal cancer, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endometrial cancer, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, Insulin signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-small cell lung cancer, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Renal cell carcinoma, Salmonella infection, Serotonergic synapse, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid cancer, Thyroid hormone signaling pathway, Toll-like receptor signaling pathway, VEGF signaling pathway, Vascular smooth muscle contraction, Yersinia infection, cAMP signaling pathway, cGMP-PKG signaling pathway, mTOR signaling pathway 💬[1] 280
146 Cobiprostone [1] Cobiprostone[1] D08893 --[1] 46
147 Cobitolimod [1] COBITOLIMOD[1] D12275 [1] TLR9 💬[9] African trypanosomiasis, Chagas disease, Herpes simplex virus 1 infection, Malaria, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer, Salmonella infection, Toll-like receptor signaling pathway, Tuberculosis 💬[1] 97
148 Cocoa [2] Chocolate; Cocoa---[1] 6
149 Coconut [1] Coconut---[1] 13
150 Coconut oil [1] Coconut oil[1] D05326 --[1] 13
151 Cod liver oil [1] Cod liver oil[1] D03578 --[1] 46
152 Cod, unspecified [0] ---[1] 46
153 Coenzyme A [1] Coenzyme A---[1] 246
154 Coenzyme M [2] MESNA; UROMITEXAN---[10] 11, 13, 44, 45, 51, 60, 65, 85, 96, 164
155 Coffea arabica seed, roasted [1] Coffee---[1] 97
156 Colchicine [2] COLCHICINA; Colchicine[1] D00570 [9] TUBB,
TUBB1,
TUBB2A,
TUBB2B,
TUBB3,
TUBB4A,
TUBB4B,
TUBB6,
TUBB8 💬		[10] Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Prion disease, Salmonella infection 💬[7] 2, 42, 46, 56, 93, 210, 266
157 Colesevelam [2] Cholestagel; Colesevelam[1] D07743 --[2] 96, 260
158 Colestipol [1] Colestipol[1] D07771 --[1] 254
159 Colistimethate [3] COLISTIMETHATE; COLISTIMETHATE SODIUM; Colobreathe---[1] 299
160 Colistin [1] COLISTIN[1] D07746 --[1] 299
161 Conestat alfa [1] COMPLEMENT C1 ESTERASE INHIBITOR[1] D10845 [3] C1R,
C1S,
KLKB1 💬		[6] Complement and coagulation cascades, Coronavirus disease - COVID-19, Pertussis, Phagosome, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[1] 61
162 Conivaptan [1] Conivaptan[1] D07748 [2] AVPR1A,
AVPR2 💬		[5] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vascular smooth muscle contraction, Vasopressin-regulated water reabsorption 💬[1] 86
163 Conjugated estrogens [1] Conjugated equine estrogens[1] D04070 --[1] 49
164 Copper [2] Copper; Nicotinamide---[4] 2, 169, 170, 171
165 Corn [1] Corn---[2] 46, 240
166 Corticorelin [1] Corticotropin-releasing hormone[1] D03905 [2] CRHR1,
CRHR2 💬		[4] Cushing syndrome, Long-term depression, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 75
167 Corticorelin ovine triflutate [1] Acthrel[1] D03592 [2] CRHR1,
CRHR2 💬		[4] Cushing syndrome, Long-term depression, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 75
168 Corticotropin [5] ACTH; Acthar; Adrenocorticotropic hormone; Corticotrophin; Corticotropin[1] D00146 [1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[12] 2, 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222
169 Cortisone [1] Cortisone[1] D07749 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 81
170 Cortisone acetate [1] Cortisone acetate[1] D00973 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 81
171 Corynebacterium diphtheriae [1] Corynebacterium diphtheriae---[1] 11
172 Corynebacterium diphtheriae CRM197 protein [1] CRM197---[3] 11, 13, 46
173 Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) [2] Boostrix; DIPHTHERIA TOXOID---[2] 13, 46
174 Cotoretigene toliparvovec [1] Cotoretigene Toliparvovec---[1] 90
175 Cow milk [1] Milk---[1] 98
176 CR002 [1] CR002---[1] 299
177 CR6086 [1] CR6086---[1] 46
178 Cranberry [1] Cranberry---[1] 13
179 Creatine [1] Creatine---[11] 1, 2, 5, 6, 8, 46, 49, 50, 113, 156, 201
180 Creatinine [1] Creatinine[1] D03600 --[5] 2, 46, 60, 70, 222
181 Creatinolfosfate [0] [1] D07162 --[1] 13
182 Crizotinib [1] Crizotinib[1] D09731 [1] ALK 💬[3] Non-small cell lung cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer 💬[1] 34
183 Crocin [1] Crocin---[1] 6
184 Cromoglicic acid [4] Cromoglicate; Cromoglycate; Cromolyn; Cromolyn Sodium[1] D07753 --[3] 2, 85, 98
185 Crovalimab [1] CROVALIMAB[1] D11696 [1] C5 💬[11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[2] 62, 109
186 CRx-139 [1] CRX-139---[1] 46
187 CTI-1601 [1] CTI-1601---[1] 18
188 Cultivated mushroom [1] Mushroom---[2] 6, 46
189 Curcumin [1] Curcumin---[10] 2, 13, 46, 67, 74, 94, 96, 97, 139, 299
190 CV-MG01 [1] CV-MG01---[1] 11
191 CVnCoV [1] SARS-COV-2 mRNA Vaccine---[1] 13
192 CX501 [1] CX501---[1] 36
193 CX516 [1] CX516---[1] 206
194 CXA-10 [1] CXA-10---[2] 86, 222
195 Cyanocobalamin [2] Cianocobalamina; Vitamin B12[4] D00166 ,
D03615 ,
D03616 ,
D03617 		--[5] 6, 13, 201, 229, 299
196 Cyclic adenosine monophosphate [1] AMPC---[1] 84
197 Cyclophosphamide [6] Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; Cyclophosphamide; Cyclophosphamidum; Cytoxan[2] D00287 ,
D07760 		--[44] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 274, 283, 284, 285, 288, 326, 331
198 Cyclosporine [10] CICLOSPORIN; Ciclosporina; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine; Cyclosporine A; Ikervis; Neoral; Restasis[1] D00184 [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[44] 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326
199 Cysteamine [8] 2-aminoethanethiol; Beta-Mercaptoethylamine; CYSTADROPS; CYSTAGON; Cysteamine; Mercaptamina; Mercaptamine; PROCYSBI[1] D03634 --[4] 8, 19, 21, 299
200 Cysteine [2] Cysteine; Cysteine hydrochloride---[10] 13, 19, 34, 84, 85, 88, 90, 254, 296, 310
201 Cytarabine [1] Cytarabine[1] D00168 --[7] 11, 13, 14, 25, 49, 60, 65