Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Afamelanotide [2] Afamelanotide; SCENESSE[1] Afamelanotide 💬 [1] MC1R 💬 [2] Melanogenesis, Neuroactive ligand-receptor interaction 💬[3] 159, 161, 254 💬
2 Chlorpromazine [2] Chlorpromazine; Chlorpromazine Hydrochloride[1] Chlorpromazine 💬 [13] ADRA2A,
ADRA2B,
ADRA2C,
CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5,
DRD2,
HRH1,
HTR2A,
HTR2B,
HTR2C 💬 		[22] Alcoholism, Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Cocaine addiction, Dopaminergic synapse, Gap junction, Gastric acid secretion, Inflammatory mediator regulation of TRP channels, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Rap1 signaling pathway, Regulation of actin cytoskeleton, Salivary secretion, Serotonergic synapse, Taste transduction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 254 💬
3 Cholestyramine [4] Cholestyramine; COLESTIRAMINA; COLESTYRAMINE; Questran---[3] 13, 79, 254 💬
4 Cimetidine [1] Cimetidine[1] Cimetidine 💬 [1] HRH2 💬 [3] Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬[2] 2, 254 💬
5 Colestipol [1] Colestipol[1] Colestipol 💬 --[1] 254 💬
6 Cysteine [2] Cysteine; Cysteine hydrochloride---[10] 13, 19, 34, 84, 85, 88, 90, 254, 296, 310 💬
7 Deferasirox [2] DEFERASIROX; EXJADE[1] Deferasirox 💬 --[3] 254, 284, 286 💬
8 Givosiran [1] Givosiran[1] Givosiran 💬 [1] ALAS1 💬 [4] Biosynthesis of cofactors, Glycine, serine and threonine metabolism, Metabolic pathways, Porphyrin metabolism 💬[1] 254 💬
9 Heme arginate [1] Heme arginate---[1] 254 💬
10 Hemin [2] Hemin; Panhematin[1] Hemin 💬 [2] ALAS1,
ALAS2 💬 		[4] Biosynthesis of cofactors, Glycine, serine and threonine metabolism, Metabolic pathways, Porphyrin metabolism 💬[1] 254 💬
11 Hydroxychloroquine [3] Hydroxychloroquine; HYDROXYCHLOROQUINE SULFATE; PLAQUENIL[1] Hydroxychloroquine 💬 --[27] 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299 💬
12 Iron [1] Iron---[6] 18, 96, 97, 238, 254, 284 💬
13 Isoniazid [1] Isoniazid[1] Isoniazid 💬 --[2] 65, 254 💬
14 Luteinizing hormone [1] Luteinizing hormone---[1] 254 💬
15 Porphobilinogen [1] Porphobilinogen---[1] 254 💬
16 Stannsoporfin [1] Tin mesoporphyrin[1] Stannsoporfin 💬 [2] HMOX1,
HMOX2 💬 		[10] Chemical carcinogenesis - reactive oxygen species, Ferroptosis, Fluid shear stress and atherosclerosis, HIF-1 signaling pathway, Hepatocellular carcinoma, Metabolic pathways, MicroRNAs in cancer, Mineral absorption, Pathways in cancer, Porphyrin metabolism 💬[1] 254 💬