Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Acetaminophen
(Synonym: Otis Clapp Mygrex)		[4] Acetaminophen; Paracetamol; Tylenol; Ultracet[1] D00217 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[15] 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337
2 Acetic acid
(Synonym: Otic Edge)		[2] Acetic acid; Ethanoate[1] D00010 --[2] 97, 251
3 Allantoin
(Synonym: Burn-B Gone OTC)		[1] ALLANTOIN[1] D00121 --[1] 36
4 Aloe vera leaf
(Synonym: C Ottways Lax Tab)		[3] Aloe; Aloe vera; Aloe vera gel---[2] 97, 226
5 Apremilast
(Synonym: Otezla)		[2] Apremilast; Otezla[1] D08860 (Name: Otezla (TN))[4] PDE4A,
PDE4B,
PDE4C,
PDE4D 💬		[5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬[7] 46, 50, 56, 97, 107, 162, 271
6 Baricitinib [2] BARICITINIB; OLUMIANT[1] D10308 (Name: OTHER BARICITINIB)[2] JAK1,
JAK2 💬		[35] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[13] 2, 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325
7 Betamethasone
(Synonym: Garasone Ophthalmic and Otic Solution)		[1] Betamethasone[1] D00244 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[8] 2, 28, 46, 65, 83, 90, 96, 235
8 Calcium carbonate
(Synonym: Relief OTC antacid)		[3] Calcio carbonato; Calcium; Calcium carbonate[2] D00932 ,
D10802 		--[9] 13, 19, 46, 53, 75, 96, 235, 274, 299
9 Capsaicin
(Synonym: Megrix OTC)		[2] Capsaicin; Qutenza[1] D00250 [1] TRPV1 💬[2] Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[3] 6, 86, 226
10 Chlorpheniramine
(Synonym: Otis Clapp Valihist)		[1] Clorfenamina[1] D07398 [1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[1] 14
11 Ciprofloxacin
(Synonym: Otiprio)		[2] Ciprofloxacin; Ciprofloxacin hydrochloride[1] D00186 (Name: Otiprio (TN))--[5] 2, 60, 96, 97, 299
12 Ethanol
(Synonym: hand sanitizer OTC)		[3] Alcohol; Ethanol; PREDNISONE[1] D06542 --[5] 58, 97, 279, 280, 298
13 Fluocinolone acetonide
(Synonym: Otixal)		[2] Fluocinolone Acetonide; Iluvien[1] D01825 (Name: FLAC OTIC OIL)[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 90
14 Gentamicin
(Synonym: Garatec Otic Dps 5mg/ml)		[2] Gentamicin; Gentamicin Sulfate[1] D08013 --[3] 36, 113, 299
15 Ginger
(Synonym: C Ottways Lax Tab)		[1] Ginger[1] D06744 --[2] 46, 271
16 Glycyrrhiza glabra
(Synonym: C Ottways Lax Tab)		[3] Glycyrrhiza; Glycyrrhiza glabra; GLYCYRRHIZA GLABRA ROOT---[2] 53, 97
17 Hydrocortisone
(Synonym: Oti Rx)		[6] Cortef; Cortisol; Cortisone; HYDROCORTISONE; Hydrocortisone cream; Hydrocortisonum[1] D00088 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[10] 6, 41, 46, 53, 75, 78, 81, 83, 97, 299
18 Hydrocortisone acetate
(Synonym: Otizol HC Liq)		[2] Hydrocortisone; HYDROCORTISONE ACETATE[1] D00165 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 97
19 Ibuprofen
(Synonym: Otis Clapp Ultraprin)		[2] IBUPROFEN; IBUPROFEN 200MG[1] D00126 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[7] 13, 46, 65, 107, 113, 271, 299
20 Lidocaine
(Synonym: Otizol HC Liq)		[4] Aloe; Lidocaine; Lignocaine; Xylocaine[2] D00358 ,
D08127 		[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256
21 Methotrexate
(Synonym: Otrexup)		[6] Methotrexat; Methotrexate; METHOTREXATE SODIUM; METOJECT; Metotrexato; Méthotrexate[1] D00142 (Name: Otrexup (TN))[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331
22 Moderna COVID-19 Vaccine [4] COVID-19 Vaccine Moderna; Elasomeran; Moderna COVID-19 Vaccine; Spikevax[1] D12114 (Name: OTHER MODERNA COVID-19 VACCINE)--[5] 13, 46, 51, 65, 299
23 Neomycin
(Synonym: Otizol HC Liq)		[1] Neomycin[1] D08260 --[3] 96, 97, 296
24 Omeprazole
(Synonym: Prilosec OTC)		[4] Losec; Omeprazol; Omeprazole; OMEPRAZOLE MAGNESIUM[1] D00455 [2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[14] 6, 8, 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299
25 Otelixizumab [1] Otelixizumab[1] D08959 (Name: Otelixizumab)[3] CD3D,
CD3E,
CD3G 💬		[11] Chagas disease, Epstein-Barr virus infection, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human immunodeficiency virus 1 infection, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬[1] 46
26 Otilimab [1] OTILIMAB[1] D11343 (Name: Otilimab)[1] CSF2 💬[16] Acute myeloid leukemia, Amoebiasis, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, IL-17 signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Natural killer cell mediated cytotoxicity, Rheumatoid arthritis, Shigellosis, T cell receptor signaling pathway, TNF signaling pathway, Transcriptional misregulation in cancer 💬[1] 46
27 Phenylephrine
(Synonym: Otis Clapp Emagrin Forte)		[1] Phenylephrine[1] D08365 [3] ADRA1A,
ADRA1B,
ADRA1D 💬		[7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 22
28 Senna leaf
(Synonym: C Ottways Lax Tab)		[1] Senna[1] D06751 --[1] 291
29 Sodium bicarbonate
(Synonym: Relief OTC antacid)		[1] Sodium Bicarbonate[1] D01203 --[1] 299
30 Tozinameran [2] Comirnaty; Tozinameran[1] D11971 (Name: OTHER BNT162B2)--[5] 13, 46, 51, 53, 299
31 Zinc acetate
(Synonym: Otozin)		[2] Wilzin; Zinc acetate[1] D06408 --[2] 171, 299
32 Zinc oxide
(Synonym: Coppertone Sunscreen Lotion Defend & Care Face Clearzinc + Other Sunscreen Ingredients)		[1] Zinc oxide[1] D01170 --[1] 156