Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Acetaminophen
(Synonym: Acetaminophen 500 Mg With 15 Mg Caffeine and 8 Mg Codeine Phosphate)		[4] Acetaminophen; PARACETAMOL; Tylenol; Ultracet[1] D00217 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[15] 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337
2 Adenine
(Synonym: TERUFLEX Blood Bag System Anticoagulant Citrate Phosphate Dextrose AND OPTISOL Red Cell Preservative)		[1] Adenin[1] D00034 --[1] 46
3 Adenosine phosphate [0] [1] D02769 (Name: Adenosine phosphate)[4] ADORA1,
ADORA2A,
ADORA2B,
ADORA3 💬		[12] Alcoholism, Calcium signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 46
4 Aluminium phosphate [1] Aluminium phosphate---[1] 46
5 Betamethasone
(Synonym: Betamethasone Sodium Phosphate and Betamethasone Acetate)		[1] Betamethasone[1] D00244 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[8] 2, 28, 46, 65, 83, 90, 96, 235
6 Caffeine
(Synonym: Acetaminophen 325 Mg With 15 Mg Caffeine and 8 Mg Codeine Phosphate)		[1] Caffeine[2] D00528 ,
D01453 		[11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 2, 6, 21, 46, 78, 96, 97, 265
7 Carvedilol
(Synonym: Carvedilol Phosphate)		[1] Carvedilol[1] D00255 [5] ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
ADRB2 💬		[13] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 57, 86, 113, 210
8 Chloroquine
(Synonym: Chloroquine Phosphate)		[1] Chloroquine[1] D02366 --[3] 46, 49, 95
9 Cipaglucosidase alfa
(Synonym: Recombinant human acid alpha-glucosidase optimized for high expression of mannose 6-phosphate)		[1] Cipaglucosidase Alfa[1] D11798 [1] GAA 💬[4] Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism 💬[1] 256
10 Citric acid
(Synonym: TERUFLEX Blood Bag System with Diversion Blood Sampling Arm Anticoagulant Citrate Phosphate Dextrose Red Cell Preservative)		[1] Citric acid[1] D01222 --[2] 53, 291
11 Clindamycin
(Synonym: Clindamycin Phosphate and Tretinion)		[2] CLINDAMYCIN; Dalacin C phosphate[1] D00277 --[2] 46, 299
12 D-glucose
(Synonym: Anticoagulant Citrate Phosphate Dextrose Blood-Pack Units in PL 146 Plastic)		[2] D-glucose; Glucose[1] D00009 --[3] 49, 86, 88
13 Dexamethasone
(Synonym: PMS-dexamethasone Sod Phosphate Dps 1mg/ml)		[5] Decadron; Dexametasona; Dexamethasone; DEXAMETHASONE SODIUM PHOSPHATE; Maxidex[1] D00292 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[22] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 81, 84, 96, 97, 162, 222, 235, 257, 283, 296, 299
14 Dextrose, unspecified form
(Synonym: Anticoagulant Solution Citrate Phosphate Dextrose)		[3] Dextrose; Glucose; Smofkabiven---[16] 2, 6, 13, 49, 50, 60, 65, 66, 70, 86, 88, 96, 97, 226, 257, 299
15 Fludarabine
(Synonym: Fludarabine Phosphate Injection)		[4] FLUDARA; Fludarabina; Fludarabine; Fludarabine phosphate[1] D07966 [1] RRM1 💬[6] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism 💬[20] 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326
16 Levomefolic acid
(Synonym: Levomefolate Calcium-Pyridoxal Phosphate-Mecobalamin)		[1] L-methylfolate[1] D09353 --[2] 6, 201
17 Mannitol
(Synonym: TERUFLEX Blood Bag System Anticoagulant Citrate Phosphate Dextrose AND OPTISOL Red Cell Preservative)		[4] Aridol; Bronchitol; Mannite; Mannitol[1] D00062 --[7] 6, 13, 28, 60, 96, 113, 299
18 Mecobalamin
(Synonym: Levomefolate Calcium-Pyridoxal Phosphate-Mecobalamin)		[2] Mecobalamin; Methylcobalamin[1] D03246 --[2] 2, 70
19 Menadiol diphosphate
(Synonym: Menadiol phosphate)		[1] Menadiol Diphosphate[1] D08176 --[1] 299
20 Metformin
(Synonym: Sitagliptin Phosphate/Metformin Hydrochloride)		[5] Metformin; Metformin HCl; METFORMIN HYDROCHLORIDE; METFORMINA; Metformine[1] D04966 [2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[25] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301
21 Oseltamivir
(Synonym: Oseltamivir Phosphate)		[1] Oseltamivir[1] D08306 --[2] 97, 299
22 Phenylephrine
(Synonym: Promethazine Hydrochloride Phenylephrine Hydrochloride and Codeine Phosphate)		[1] Phenylephrine[1] D08365 [3] ADRA1A,
ADRA1B,
ADRA1D 💬		[7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 22
23 Phosphate ion [1] Phosphate---[32] 2, 3, 6, 11, 12, 13, 28, 36, 46, 49, 51, 53, 60, 62, 65, 70, 78, 81, 83, 90, 96, 97, 164, 235, 238, 256, 276, 283, 284, 285, 286, 299
24 Phosphorus P-32
(Synonym: P32 Sodium Phosphate)		[0] ---[1] 37
25 Promethazine
(Synonym: Promethazine Hydrochloride Phenylephrine Hydrochloride and Codeine Phosphate)		[1] Promethazine[1] D00494 [1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[1] 96
26 Pseudoephedrine
(Synonym: Codeine Phosphate and Pseudoephedrine Hydrochloride)		[1] Pseudoephedrine[1] D08449 [9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		[14] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 17
27 Pyridoxal phosphate [0] ---[1] 13
28 Riboflavin
(Synonym: Riboflavin 5 Phosphate Cap 50mg)		[2] Riboflavin; Vitamin B2[1] D00050 --[7] 38, 46, 96, 97, 162, 168, 265
29 Sitagliptin
(Synonym: Sitagliptin Phosphate/Metformin Hydrochloride)		[1] Sitagliptin[1] D08516 [1] DPP4 💬[1] Protein digestion and absorption 💬[4] 6, 75, 233, 299
30 Sodium chloride
(Synonym: TERUFLEX Blood Bag System Anticoagulant Citrate Phosphate Dextrose AND OPTISOL Red Cell Preservative)		[6] Lactated Ringers; Natriumchlorid; REBIF; Saline; Sodium Chloride; SPORANOX[1] D02056 --[20] 6, 11, 13, 14, 34, 41, 46, 50, 51, 53, 60, 67, 70, 96, 168, 193, 227, 228, 288, 299
31 Sodium citrate
(Synonym: TERUFLEX Blood Bag System Anticoagulant Citrate Phosphate Dextrose AND OPTISOL Red Cell Preservative)		[1] Sodium citrate[2] D01781 ,
D05855 		--[4] 67, 214, 215, 235
32 Sodium fluoride
(Synonym: NEUTRAMAXX 5000 Tri-Calcium Phosphate)		[1] Sodium fluoride[1] D00943 --[1] 51
33 Sodium glycerophosphate
(Synonym: Disodium glycerol phosphate)		[1] Smofkabiven[1] D10489 --[1] 66
34 Tretinoin
(Synonym: Clindamycin Phosphate and Tretinoin)		[5] ATRA; Retinoic acid; Tretinoin; TRETINOINA; VESANOID[1] D00094 [3] PML,
RARA,
RARB 💬		[12] Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis 💬[6] 2, 62, 63, 75, 94, 231