Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Melanoma 💬
 [1] BRAF 💬 Dabrafenib 💬 Dabrafenib [1] 34 💬
2 Melanoma 💬
 [3] BRAF, PDGFRB, RAF1 💬 Sorafenib 💬 Sorafenib [2] 34, 86 💬
3 Melanoma 💬
 [2] CDK4, CDK6 💬 Abemaciclib 💬 Abemaciclib [1] 34 💬
4 Melanoma 💬
 [1] EGFR 💬 Cetuximab 💬 Cetuximab [2] 51, 86 💬
5 Melanoma 💬
 [1] EGFR 💬 Erlotinib 💬 Erlotinib [1] 94 💬
6 Melanoma 💬
 [1] EGFR 💬 Gefitinib 💬 Gefitinib [1] 75 💬
7 Melanoma 💬
 [1] EGFR 💬 Icotinib 💬 Icotinib [1] 34 💬
8 Melanoma 💬
 [1] EGFR 💬 Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
9 Melanoma 💬
 [1] EGFR 💬 Neratinib 💬 Neratinib [1] 34 💬
10 Melanoma 💬
 [1] EGFR 💬 Tesevatinib 💬 Tesevatinib [1] 67 💬
11 Melanoma 💬
 [1] FGF23 💬 Burosumab 💬 Burosumab [1] 238 💬
12 Melanoma 💬
 [1] FGFR1 💬 Infigratinib 💬 Infigratinib [1] 276 💬
13 Melanoma 💬
 [3] FGFR1, PDGFRA, PDGFRB 💬 Nintedanib 💬 Nintedanib [5] 51, 85, 89, 227, 228 💬
14 Melanoma 💬
 [1] IGF1R 💬 Linsitinib 💬 Linsitinib [1] 232 💬
15 Melanoma 💬
 [1] IGF1R 💬 Mecasermin 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
16 Melanoma 💬
 [1] IGF1R 💬 Teprotumumab 💬 Teprotumumab [1] 51 💬
17 Melanoma 💬
 [2] MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib [1] 34 💬
18 Melanoma 💬
 [2] MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib [1] 280 💬
19 Melanoma 💬
 [2] MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib [1] 34 💬
20 Melanoma 💬
 [2] MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib [1] 34 💬
21 Melanoma 💬
 [2] MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib [4]  2 , 34, 279, 280 💬
22 Melanoma 💬
 [1] MET 💬 Cabozantinib 💬 Cabozantinib [1] 34 💬
23 Melanoma 💬
 [1] PDGFRA 💬 Imatinib 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
24 Melanoma 💬
 [2] PDGFRA, PDGFRB 💬 Nilotinib 💬 Nilotinib [5]  6 ,  8 , 34, 51, 86 💬
25 Melanoma 💬
 [2] PDGFRA, PDGFRB 💬 Sunitinib 💬 Sunitinib [2] 28, 34 💬
26 Melanoma 💬
 [1] PDGFRB 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
27 Melanoma 💬
 [1] PDGFRB 💬 Dasatinib 💬 Dasatinib [2] 51, 85 💬
28 Melanoma 💬
 [1] PIK3CA 💬 Alpelisib 💬 Alpelisib [1] 138 💬
29 Melanoma 💬
 [3] PIK3CA, PIK3CB, PIK3CD 💬 Leniolisib 💬 Leniolisib [2] 53, 65 💬
30 Melanoma 💬
 [1] PIK3CD 💬 Parsaclisib 💬 Parsaclisib [3] 35, 53, 61 💬