Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Artesunate 💬[1] Artesunate[1] Artesunate--[3] 18, 66, 96 💬
2 Baclofen 💬[1] Baclofen[2] Baclofen; Kemstro[2] GABBR1,
GABBR2 💬 		[7] Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬[8] 2, 10, 13, 18, 65, 70, 149, 206 💬
3 Bupropion 💬[1] Bupropion[2] Bupropion; Bupropion Hydrochloride[2] SLC6A2,
SLC6A3 💬 		[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[5] 8, 18, 21, 96, 171 💬
4 Calcitriol 💬[1] Calcitriol[1] Calcitriol[1] VDR 💬 [5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[9] 18, 37, 46, 49, 66, 96, 158, 235, 326 💬
5 Citalopram 💬[1] Citalopram[1] Citalopram[1] SLC6A4 💬 [2] Serotonergic synapse, Synaptic vesicle cycle 💬[7] 6, 8, 13, 18, 46, 98, 127 💬
6 Deferiprone 💬[1] Deferiprone[2] DEFERIPRONE; Ferriprox--[6] 2, 6, 18, 120, 122, 233 💬
7 Etravirine 💬[1] Etravirine[3] ETRAVIRINA; Etravirine; INTELENCE--[1] 18 💬
8 Flumazenil 💬[1] Flumazenil[1] Flumazenil[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[5] 6, 13, 17, 18, 206 💬
9 Idebenone 💬[1] Idebenone[2] Idebenone; Raxone--[6] 6, 8, 13, 18, 113, 302 💬
10 Interferon gamma-1b 💬[1] Interferon gamma-1b[2] ACTIMMUNE; Interferon gamma-1b[2] IFNGR1,
IFNGR2 💬 		[18] Chagas disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis 💬[7] 18, 65, 85, 228, 299, 301, 326 💬
11 Lenograstim 💬[1] Lenograstim[2] G-CSF; Lenograstim[1] CSF3R 💬 [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[7] 2, 13, 16, 18, 19, 57, 65 💬
12 Lithium carbonate 💬[1] Lithium carbonate[2] Lithium; Lithium Carbonate--[5] 2, 13, 17, 18, 127 💬
13 Methylprednisolone 💬[1] Methylprednisolone[4] Medrol; Methylprednisolon; Methylprednisolone; Methylprednisolone acetate[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[46] 2, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
14 Niacinamide 💬[1] Nicotinamide[3] Multivitamin; Niacinamide; Nicotinamide--[10] 2, 5, 6, 18, 49, 67, 97, 107, 162, 191 💬
15 Omaveloxolone 💬[1] Omaveloxolone[1] Omaveloxolone[1] NFE2L2 💬 [7] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Lipid and atherosclerosis, Parkinson disease, Pathways in cancer, Protein processing in endoplasmic reticulum 💬[1] 18 💬
16 Riluzole 💬[1] Riluzole[2] Rilutek; Riluzole[14] GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[23] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
17 Rosuvastatin 💬[1] Rosuvastatin[3] Crestor; Rosuvastatin; ROSUVASTATIN CALCIUM[1] HMGCR 💬 [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[11] 6, 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
18 Ubidecarenone 💬[1] Ubidecarenone[3] Coenzyme Q-10; Coenzyme Q10; CoQ10--[12] 2, 5, 6, 8, 10, 18, 46, 57, 86, 113, 214, 215 💬
19 Varenicline 💬[1] Varenicline[2] Champix; VARENICLINE[2] CHRNA4,
CHRNB2 💬 		[4] Chemical carcinogenesis - receptor activation, Cholinergic synapse, Neuroactive ligand-receptor interaction, Nicotine addiction 💬[3] 6, 18, 53 💬
20 Vatiquinone 💬[1] Vatiquinone[1] VATIQUINONE--[2] 18, 21 💬