Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Methotrexate
(Synonym: Otrexup (TN))		[1] Methotrexate (Synonym: Otrexup)[6] Methotrexat; Methotrexate; METHOTREXATE SODIUM; Metoject; METOTREXATO; Méthotrexate; [2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331
2 Ciprofloxacin
(Synonym: Otiprio (TN))		[1] Ciprofloxacin (Synonym: Cipro HC Otic Suspension)[2] CIPROFLOXACIN; CIPROFLOXACIN HYDROCHLORIDE; --[5] 2, 60, 96, 97, 299
3 Fluocinolone acetonide
(Synonym: FLAC OTIC OIL)		[1] Fluocinolone acetonide (Synonym: Synalar Bi-otic Solution)[2] Fluocinolone Acetonide; Iluvien; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 90
4 Apremilast
(Synonym: Otezla (TN))		[1] Apremilast (Synonym: Otezla)[2] Apremilast; Otezla; [4] PDE4A,
PDE4B,
PDE4C,
PDE4D 💬		[5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬[7] 46, 50, 56, 97, 107, 162, 271
5 Otelixizumab [1] Otelixizumab[1] Otelixizumab; [3] CD3D,
CD3E,
CD3G 💬		[11] Chagas disease, Epstein-Barr virus infection, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human immunodeficiency virus 1 infection, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬[1] 46
6 Baricitinib
(Synonym: OTHER BARICITINIB)		[1] Baricitinib[2] BARICITINIB; Olumiant; [2] JAK1,
JAK2 💬		[35] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[13] 2, 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325
7 Otilimab [1] Otilimab[1] OTILIMAB; [1] CSF2 💬[16] Acute myeloid leukemia, Amoebiasis, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, IL-17 signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Natural killer cell mediated cytotoxicity, Rheumatoid arthritis, Shigellosis, T cell receptor signaling pathway, TNF signaling pathway, Transcriptional misregulation in cancer 💬[1] 46
8 Tozinameran
(Synonym: OTHER BNT162B2)		[1] Tozinameran[2] Comirnaty; Tozinameran; --[5] 13, 46, 51, 53, 299
9 Elasomeran
(Synonym: OTHER MODERNA COVID-19 VACCINE)		[1] Moderna COVID-19 Vaccine[4] COVID-19 Vaccine Moderna; Elasomeran; Moderna COVID-19 Vaccine; Spikevax; --[5] 13, 46, 51, 65, 299