10. Charcot-Marie-Tooth disease Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 41 / Drugs : 46 - (DrugBank : 9) / Drug target genes : 11 - Drug target pathways : 15
Charcot-Marie-Tooth disease and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 10 | Charcot-Marie-Tooth disease | - |
| 13 | Multiple sclerosis/Neuromyelitis optica | 11.000 |
| 46 | Malignant rheumatoid arthritis | 7.443 |
| 231 | Alpha-1-antitrypsin deficiency | 6.317 |
| 298 | Hereditary pancreatitis | 6.148 |
| 226 | Interstitial cystitis with Hunners ulcer | 6.091 |
| 70 | Spinal stenosis | 6.083 |
| 51 | Scleroderma | 5.973 |
| 97 | Ulcerative colitis | 5.940 |
| 96 | Crohn disease | 5.922 |
| 6 | Parkinson disease | 5.911 |
| 2 | Amyotrophic lateral sclerosis | 4.558 |
| 168 | Ehlers-Danlos syndrome | 3.788 |
| 1 | Spinal and bulbar muscular atrophy | 3.636 |
| 36 | Epidermolysis bullosa | 3.607 |
| 86 | Pulmonary arterial hypertension | 3.436 |
| 38 | Stevens-Johnson syndrome | 3.182 |
| 114 | Non-dystrophic myotonia syndrome | 3.030 |
| 256 | Muscle glycogenosis | 2.713 |
| 127 | Frontotemporal lobar degeneration | 2.614 |
| 58 | Hypertrophic cardiomyopathy | 2.557 |
| 140 | Dorabe syndrome | 2.557 |
| 144 | Lennox-Gastaut syndrome | 2.551 |
| 193 | Prader-Willi syndrome | 2.540 |
| 107 | Juvenile idiopathic arthritis | 2.535 |
| 53 | Sjogren syndrome | 2.521 |
| 113 | Muscular dystrophy | 2.504 |
| 28 | Systemic amyloidosis | 2.479 |
| 156 | Rett syndrome | 2.450 |
| 84 | Sarcoidosis | 2.439 |
| 8 | Huntington disease | 2.435 |
| 34 | Neurofibromatosis | 2.429 |
| 149 | Hemiconvulsion hemiplegia epilepsy syndrome | 2.053 |
| 43 | Microscopic polyangiitis | 1.286 |
| 45 | Eosinophilic granulomatosis with Polyangiitis | 1.182 |
| 44 | Wegener granulomatosis | 1.130 |
| 40 | Takayasu arteritis | 1.080 |
| 42 | Polyarteritis nodosa | 1.070 |
| 41 | Giant cell arteritis | 1.017 |