Gene

Search results

No.

KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

Adrenergic signaling in cardiomyocytes 💬

[1] SCN5A 💬

Mexiletine 💬

Mexiletine

[5] 1 , 2 , 10, 113, 114 💬

Disease ID	Name
1	Spinal and bulbar muscular atrophy;Spinobulbar muscular atrophy;SBMA;Kennedy disease;Kennedy-Alter-Sung syndrome;
2	Amyotrophic lateral sclerosis;ALS;
10	Charcot-Marie-Tooth disease;CMT;
113	Muscular dystrophy;
114	Non-dystrophic myotonia syndrome;Non-dystrophic Myotonia;

Breast cancer 💬

[1] PGR 💬

Ulipristal 💬

Ulipristal

[1] 10 💬

cAMP signaling pathway 💬

[2] GABBR1, GABBR2 💬

Baclofen 💬

Baclofen

[8] 2 , 10, 13, 18, 65, 70, 149, 206 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
10	Charcot-Marie-Tooth disease;CMT;
13	Multiple sclerosis/Neuromyelitis optica;
18	Spinocerebellar degeneration;SCD;
65	Primary immunodeficiency;
70	Spinal stenosis;Extensive spinal canal stenosis;
149	Hemiconvulsion hemiplegia epilepsy syndrome;One side convulsions;Hemiplegia;Epilepsy syndrome;
206	Fragile X syndrome;

cGMP-PKG signaling pathway 💬

[1] OPRD1 💬

Naltrexone 💬

Naltrexone

[13] 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
10	Charcot-Marie-Tooth disease;CMT;
13	Multiple sclerosis/Neuromyelitis optica;
40	Takayasu arteritis;Aortitis syndrome;Pulseless disease;Aortitis syndrome;
41	Giant cell arteritis;Temporal arteritis;
42	Polyarteritis nodosa;PAN;
43	Microscopic polyangiitis;MPA;
44	Wegener granulomatosis;Multiple vasculitis granulomatous disease;Granulomatosis with polyangiitis;
45	Eosinophilic granulomatosis with Polyangiitis;EGPA;Eosinophilic multiple vasculitis granulomatous disease;Allergic granulomatous angiitis;AGA;Churg-Strauss syndrome;CSS;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
226	Interstitial cystitis with Hunners ulcer;Interstitial cystitis;

Chemical carcinogenesis - receptor activation 💬

[1] PGR 💬

Ulipristal 💬

Ulipristal

[1] 10 💬

Dopaminergic synapse 💬

[1] SCN1A 💬

Mexiletine 💬

Mexiletine

[5] 1 , 2 , 10, 113, 114 💬

Disease ID	Name
1	Spinal and bulbar muscular atrophy;Spinobulbar muscular atrophy;SBMA;Kennedy disease;Kennedy-Alter-Sung syndrome;
2	Amyotrophic lateral sclerosis;ALS;
10	Charcot-Marie-Tooth disease;CMT;
113	Muscular dystrophy;
114	Non-dystrophic myotonia syndrome;Non-dystrophic Myotonia;

Estrogen signaling pathway 💬

[2] GABBR1, GABBR2 💬

Baclofen 💬

Baclofen

[8] 2 , 10, 13, 18, 65, 70, 149, 206 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
10	Charcot-Marie-Tooth disease;CMT;
13	Multiple sclerosis/Neuromyelitis optica;
18	Spinocerebellar degeneration;SCD;
65	Primary immunodeficiency;
70	Spinal stenosis;Extensive spinal canal stenosis;
149	Hemiconvulsion hemiplegia epilepsy syndrome;One side convulsions;Hemiplegia;Epilepsy syndrome;
206	Fragile X syndrome;

Estrogen signaling pathway 💬

[1] OPRM1 💬

Naltrexone 💬

Naltrexone

[13] 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
10	Charcot-Marie-Tooth disease;CMT;
13	Multiple sclerosis/Neuromyelitis optica;
40	Takayasu arteritis;Aortitis syndrome;Pulseless disease;Aortitis syndrome;
41	Giant cell arteritis;Temporal arteritis;
42	Polyarteritis nodosa;PAN;
43	Microscopic polyangiitis;MPA;
44	Wegener granulomatosis;Multiple vasculitis granulomatous disease;Granulomatosis with polyangiitis;
45	Eosinophilic granulomatosis with Polyangiitis;EGPA;Eosinophilic multiple vasculitis granulomatous disease;Allergic granulomatous angiitis;AGA;Churg-Strauss syndrome;CSS;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
226	Interstitial cystitis with Hunners ulcer;Interstitial cystitis;

Estrogen signaling pathway 💬

[1] PGR 💬

Ulipristal 💬

Ulipristal

[1] 10 💬

GABAergic synapse 💬

[2] GABBR1, GABBR2 💬

Baclofen 💬

Baclofen

[8] 2 , 10, 13, 18, 65, 70, 149, 206 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
10	Charcot-Marie-Tooth disease;CMT;
13	Multiple sclerosis/Neuromyelitis optica;
18	Spinocerebellar degeneration;SCD;
65	Primary immunodeficiency;
70	Spinal stenosis;Extensive spinal canal stenosis;
149	Hemiconvulsion hemiplegia epilepsy syndrome;One side convulsions;Hemiplegia;Epilepsy syndrome;
206	Fragile X syndrome;

GnRH secretion 💬

[2] GABBR1, GABBR2 💬

Baclofen 💬

Baclofen

[8] 2 , 10, 13, 18, 65, 70, 149, 206 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
10	Charcot-Marie-Tooth disease;CMT;
13	Multiple sclerosis/Neuromyelitis optica;
18	Spinocerebellar degeneration;SCD;
65	Primary immunodeficiency;
70	Spinal stenosis;Extensive spinal canal stenosis;
149	Hemiconvulsion hemiplegia epilepsy syndrome;One side convulsions;Hemiplegia;Epilepsy syndrome;
206	Fragile X syndrome;

Morphine addiction 💬

[2] GABBR1, GABBR2 💬

Baclofen 💬

Baclofen

[8] 2 , 10, 13, 18, 65, 70, 149, 206 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
10	Charcot-Marie-Tooth disease;CMT;
13	Multiple sclerosis/Neuromyelitis optica;
18	Spinocerebellar degeneration;SCD;
65	Primary immunodeficiency;
70	Spinal stenosis;Extensive spinal canal stenosis;
149	Hemiconvulsion hemiplegia epilepsy syndrome;One side convulsions;Hemiplegia;Epilepsy syndrome;
206	Fragile X syndrome;

Morphine addiction 💬

[1] OPRM1 💬

Naltrexone 💬

Naltrexone

[13] 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
10	Charcot-Marie-Tooth disease;CMT;
13	Multiple sclerosis/Neuromyelitis optica;
40	Takayasu arteritis;Aortitis syndrome;Pulseless disease;Aortitis syndrome;
41	Giant cell arteritis;Temporal arteritis;
42	Polyarteritis nodosa;PAN;
43	Microscopic polyangiitis;MPA;
44	Wegener granulomatosis;Multiple vasculitis granulomatous disease;Granulomatosis with polyangiitis;
45	Eosinophilic granulomatosis with Polyangiitis;EGPA;Eosinophilic multiple vasculitis granulomatous disease;Allergic granulomatous angiitis;AGA;Churg-Strauss syndrome;CSS;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
226	Interstitial cystitis with Hunners ulcer;Interstitial cystitis;

Neuroactive ligand-receptor interaction 💬

[2] GABBR1, GABBR2 💬

Baclofen 💬

Baclofen

[8] 2 , 10, 13, 18, 65, 70, 149, 206 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
10	Charcot-Marie-Tooth disease;CMT;
13	Multiple sclerosis/Neuromyelitis optica;
18	Spinocerebellar degeneration;SCD;
65	Primary immunodeficiency;
70	Spinal stenosis;Extensive spinal canal stenosis;
149	Hemiconvulsion hemiplegia epilepsy syndrome;One side convulsions;Hemiplegia;Epilepsy syndrome;
206	Fragile X syndrome;

Neuroactive ligand-receptor interaction 💬

[3] OPRD1, OPRK1, OPRM1 💬

Naltrexone 💬

Naltrexone

[13] 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
10	Charcot-Marie-Tooth disease;CMT;
13	Multiple sclerosis/Neuromyelitis optica;
40	Takayasu arteritis;Aortitis syndrome;Pulseless disease;Aortitis syndrome;
41	Giant cell arteritis;Temporal arteritis;
42	Polyarteritis nodosa;PAN;
43	Microscopic polyangiitis;MPA;
44	Wegener granulomatosis;Multiple vasculitis granulomatous disease;Granulomatosis with polyangiitis;
45	Eosinophilic granulomatosis with Polyangiitis;EGPA;Eosinophilic multiple vasculitis granulomatous disease;Allergic granulomatous angiitis;AGA;Churg-Strauss syndrome;CSS;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
226	Interstitial cystitis with Hunners ulcer;Interstitial cystitis;

Oocyte meiosis 💬

[1] PGR 💬

Ulipristal 💬

Ulipristal

[1] 10 💬

Progesterone-mediated oocyte maturation 💬

[1] PGR 💬

Ulipristal 💬

Ulipristal

[1] 10 💬

Sphingolipid signaling pathway 💬

[1] OPRD1 💬

Naltrexone 💬

Naltrexone

[13] 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
10	Charcot-Marie-Tooth disease;CMT;
13	Multiple sclerosis/Neuromyelitis optica;
40	Takayasu arteritis;Aortitis syndrome;Pulseless disease;Aortitis syndrome;
41	Giant cell arteritis;Temporal arteritis;
42	Polyarteritis nodosa;PAN;
43	Microscopic polyangiitis;MPA;
44	Wegener granulomatosis;Multiple vasculitis granulomatous disease;Granulomatosis with polyangiitis;
45	Eosinophilic granulomatosis with Polyangiitis;EGPA;Eosinophilic multiple vasculitis granulomatous disease;Allergic granulomatous angiitis;AGA;Churg-Strauss syndrome;CSS;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
96	Crohn disease;Terminal ileitis;
97	Ulcerative colitis;
226	Interstitial cystitis with Hunners ulcer;Interstitial cystitis;

Taste transduction 💬

[2] GABBR1, GABBR2 💬

Baclofen 💬

Baclofen

[8] 2 , 10, 13, 18, 65, 70, 149, 206 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis;ALS;
10	Charcot-Marie-Tooth disease;CMT;
13	Multiple sclerosis/Neuromyelitis optica;
18	Spinocerebellar degeneration;SCD;
65	Primary immunodeficiency;
70	Spinal stenosis;Extensive spinal canal stenosis;
149	Hemiconvulsion hemiplegia epilepsy syndrome;One side convulsions;Hemiplegia;Epilepsy syndrome;
206	Fragile X syndrome;

Taste transduction 💬

[3] SCN2A, SCN3A, SCN9A 💬

Mexiletine 💬

Mexiletine

[5] 1 , 2 , 10, 113, 114 💬

Disease ID	Name
1	Spinal and bulbar muscular atrophy;Spinobulbar muscular atrophy;SBMA;Kennedy disease;Kennedy-Alter-Sung syndrome;
2	Amyotrophic lateral sclerosis;ALS;
10	Charcot-Marie-Tooth disease;CMT;
113	Muscular dystrophy;
114	Non-dystrophic myotonia syndrome;Non-dystrophic Myotonia;