DR info

Clinical trials : 899 / Drugs : 684 - (DrugBank : 99) / Drug target genes : 51 - Drug target pathways : 182

Lysosomal storage disease and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)

ID	Diseases (Sorted by score)	Score
19	Lysosomal storage disease	-
96	Crohn disease	23.620
13	Multiple sclerosis/Neuromyelitis optica	22.227
46	Malignant rheumatoid arthritis	18.854
284	Diamond-Blackfan anemia	15.581
49	Systemic lupus erythematosus	15.449
65	Primary immunodeficiency	14.478
285	Fanconi anemia	13.952
60	Aplastic anemia	13.696
6	Parkinson disease	12.038
283	Acquired pure red cell aplasia	11.520
20	Adrenoleukodystrophy	11.265
53	Sjogren syndrome	10.962
41	Giant cell arteritis	10.788
66	IgA nephropathy	10.411
55	Relapsing polychondritis	10.229
45	Eosinophilic granulomatosis with Polyangiitis	10.069
326	Osteopetrosis	9.522
164	Oculocutaneous albinism	9.494
62	Paroxysmal nocturnal hemoglobinuria	8.981
36	Epidermolysis bullosa	8.633
222	Primary nephrotic syndrome	8.622
234	Peroxisomal disease (except Adrenoleukodystrophy)	8.575
224	Purpura nephritis	8.534
107	Juvenile idiopathic arthritis	8.377
95	Autoimmune hepatitis	8.348
93	Primary biliary cholangitis	8.292
286	Hereditary sideroblastic anemia	8.000
299	Cystic fibrosis	7.957
40	Takayasu arteritis	7.936
50	Dermatomyositis	7.807
42	Polyarteritis nodosa	7.725
51	Scleroderma	7.547
2	Amyotrophic lateral sclerosis	7.449
11	Myasthenia gravis	7.174
85	Idiopathic interstitial pneumonia	7.115
97	Ulcerative colitis	7.061
162	Pemphigoid	6.606
86	Pulmonary arterial hypertension	6.366
56	Behcet disease	6.259
75	Cushing disease	6.101
26	HTLV-1-associated myelopathy	6.059
226	Interstitial cystitis with Hunners ulcer	6.012
151	Rasmussen encephalitis	6.000
61	Autoimmune hemolytic anemia	5.822
28	Systemic amyloidosis	5.208
302	Leber hereditary optic neuropathy	5.000
274	Osteogenesis Imperfecta	4.969
228	Bronchiolitis obliterans	4.836
39	Toxic epidermal necrolysis	4.713
38	Stevens-Johnson syndrome	4.700
35	Pemphigus	4.375
84	Sarcoidosis	4.122
113	Muscular dystrophy	4.103
160	Congenital ichthyosis	4.071
43	Microscopic polyangiitis	3.855
300	IgG4-related disease	3.645
269	Pyogenic arthritis	3.645
44	Wegener granulomatosis	3.622
98	Eosinophilic gastrointestinal disease	3.535
271	Ankylosing spondylitis	3.535
64	Thrombotic thrombocytopenic purpura	3.462
270	Chronic recurrent multifocal osteomyelitis	2.744
94	Primary sclerosing cholangitis	2.252
296	Biliary atresia	2.185
63	Idiopathic thrombocytopenic purpura	2.185
256	Muscle glycogenosis	2.130
331	Idiopathic multicentric castleman disease	2.130
58	Hypertrophic cardiomyopathy	2.106
257	Hepatic glycogenosis	2.000
139	Congenital cerebral hypomyelination	2.000
298	Hereditary pancreatitis	1.995
158	Tuberous sclerosis	1.968
227	Osler disease	1.951
16	Crow-Fukase syndrome	1.852
15	Inclusion body myositis	1.602
254	Porphyria	1.583
218	Alport syndrome	1.565
17	Multiple system atrophy	1.432
172	Hypophosphatasia	1.353
80	Resistance to thyroid hormone	1.353
90	Retinitis pigmentosa	1.193
57	Idiopathic dilated cardiomyopathy	1.087
106	Cryopyrin-associated periodic syndrome	1.029
91	Budd-Chiari syndrome	1.029
238	Vitamin D-resistant rickets	1.029
235	Hypoparathyroidism	1.029
5	Progressive supranuclear palsy	1.027
70	Spinal stenosis	1.020
137	Focal cortical dysplasia	1.000
192	Cockayne syndrome	1.000
277	Lymphangiomatosis	1.000
281	Klippel-Trenaunay-Weber syndrome	1.000
191	Werner syndrome	1.000
52	Mixed connective tissue disease	1.000
220	Rapidly progressive glomerulonephritis	1.000
30	Distal myopathy	1.000