DR info

Clinical trials : 72 / Drugs : 53 - (DrugBank : 16) / Drug target genes : 19 - Drug target pathways : 35

Porphyria and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)

ID	Diseases (Sorted by score)	Score
254	Porphyria	-
2	Amyotrophic lateral sclerosis	10.616
6	Parkinson disease	9.179
13	Multiple sclerosis/Neuromyelitis optica	7.778
5	Progressive supranuclear palsy	4.919
226	Interstitial cystitis with Hunners ulcer	3.947
8	Huntington disease	3.810
86	Pulmonary arterial hypertension	3.739
98	Eosinophilic gastrointestinal disease	3.334
323	Aromatic L-amino acid decarboxylase deficiency	3.000
156	Rett syndrome	2.981
299	Cystic fibrosis	2.151
46	Malignant rheumatoid arthritis	2.028
26	HTLV-1-associated myelopathy	1.801
296	Biliary atresia	1.725
21	Mitochondrial disease	1.708
206	Fragile X syndrome	1.657
53	Sjogren syndrome	1.651
17	Multiple system atrophy	1.618
70	Spinal stenosis	1.595
19	Lysosomal storage disease	1.583
4	Primary lateral sclerosis	1.507
212	Tricuspid atresia	1.421
118	Myelomeningocele	1.421
187	Kabuki syndrome	1.404
169	Menkes disease	1.316
170	Occipital horn syndrome	1.316
11	Myasthenia gravis	1.123
140	Dorabe syndrome	1.105
90	Retinitis pigmentosa	1.100
107	Juvenile idiopathic arthritis	1.085
280	Huge arteriovenous malformation with cervicofacial or limb lesion	1.015