DR info

Clinical trials : 237 / Drugs : 123 - (DrugBank : 29) / Drug target genes : 51 - Drug target pathways : 75

Spinal muscular atrophy and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)

ID	Diseases (Sorted by score)	Score
3	Spinal muscular atrophy	-
13	Multiple sclerosis/Neuromyelitis optica	45.983
6	Parkinson disease	41.411
2	Amyotrophic lateral sclerosis	38.440
5	Progressive supranuclear palsy	37.572
206	Fragile X syndrome	28.157
18	Spinocerebellar degeneration	26.997
17	Multiple system atrophy	24.672
97	Ulcerative colitis	23.421
156	Rett syndrome	23.313
8	Huntington disease	22.881
205	Fragile X syndrome related disease	20.456
193	Prader-Willi syndrome	19.507
140	Dorabe syndrome	18.671
144	Lennox-Gastaut syndrome	18.531
46	Malignant rheumatoid arthritis	17.926
70	Spinal stenosis	16.795
21	Mitochondrial disease	16.352
152	PCDH19 related syndrome	16.000
96	Crohn disease	15.883
34	Neurofibromatosis	15.588
22	Moyamoya disease	15.082
158	Tuberous sclerosis	14.663
145	West syndrome	14.038
203	22q11.2 deletion syndrome	14.000
231	Alpha-1-antitrypsin deficiency	13.428
201	Angelman syndrome	12.954
296	Biliary atresia	11.958
272	Fibrodysplasia ossificans progressiva	11.704
298	Hereditary pancreatitis	11.181
155	Acquired aphasia with convulsive disorder	10.993
98	Eosinophilic gastrointestinal disease	10.241
75	Cushing disease	9.564
36	Epidermolysis bullosa	8.477
127	Frontotemporal lobar degeneration	8.278
84	Sarcoidosis	7.847
102	Rubinstein-Taybi syndrome	7.000
85	Idiopathic interstitial pneumonia	6.635
256	Muscle glycogenosis	5.376
215	Tetralogy of Fallot	5.264
4	Primary lateral sclerosis	5.068
12	Congenital myasthenic syndrome	5.000
233	Wolfram syndrome	4.791
65	Primary immunodeficiency	4.606
113	Muscular dystrophy	4.605
78	Hypopituitarism	4.462
89	Lymphangioleiomyomatosis	4.019
222	Primary nephrotic syndrome	3.217
49	Systemic lupus erythematosus	3.124
11	Myasthenia gravis	3.023
331	Idiopathic multicentric castleman disease	2.960
26	HTLV-1-associated myelopathy	2.638
14	Chronic inflammatory demyelinating polyneuropathy	2.358
90	Retinitis pigmentosa	2.317
251	Urea cycle disorder	2.292
86	Pulmonary arterial hypertension	2.201
337	Homocystinuria	2.000
76	Pituitary gonadotropin secretion hyperthyroidism	1.585
1	Spinal and bulbar muscular atrophy	1.019
299	Cystic fibrosis	1.012
111	Congenital myopathy	1.000
191	Werner syndrome	1.000
220	Rapidly progressive glomerulonephritis	1.000
30	Distal myopathy	1.000