KEGG DRUG

Search results

No.

DrugBank

Drug (Description in trials)

KEGG DRUG

KEGG GENES

KEGG PATHWAY

Disease ID

Acetaminophen

[4] Acetaminophen; PARACETAMOL; Tylenol; Ultracet

[1] Acetaminophen 💬

[2] PTGS1,
PTGS2 💬

[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬

[15] 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬

Disease ID	Name
3	Spinal muscular atrophy
6	Parkinson disease
11	Myasthenia gravis
13	Multiple sclerosis/Neuromyelitis optica
34	Neurofibromatosis
35	Pemphigus
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
51	Scleroderma
70	Spinal stenosis
86	Pulmonary arterial hypertension
222	Primary nephrotic syndrome
256	Muscle glycogenosis
271	Ankylosing spondylitis
337	Homocystinuria

Amifampridine

[2] Amifampridine; Firdapse

[1] Amifampridine 💬

[4] KCNA4,
KCNC3,
KCND2,
KCND3 💬

Name	Full Name
KCNA4	potassium voltage-gated channel subfamily A member 4
KCNC3	potassium voltage-gated channel subfamily C member 3
KCND2	potassium voltage-gated channel subfamily D member 2
KCND3	potassium voltage-gated channel subfamily D member 3

[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬

[3] 3, 11, 12 💬

Apitegromab

[1] Apitegromab

[1] Apitegromab 💬

[1] MSTN 💬

[1] Cytokine-cytokine receptor interaction 💬

[1] 3 💬

Branaplam

[1] Branaplam

[1] Branaplam 💬

[1] SMN2 💬

[2] 3, 8 💬

Celecoxib

[2] Celebrex; Celecoxib

[1] Celecoxib 💬

[1] PTGS2 💬

[22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬

[10] 2, 3, 34, 46, 70, 89, 107, 161, 171, 271 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
3	Spinal muscular atrophy
34	Neurofibromatosis
46	Malignant rheumatoid arthritis
70	Spinal stenosis
89	Lymphangioleiomyomatosis
107	Juvenile idiopathic arthritis
161	Familial benign chronic pemphigus
171	Wilson disease
271	Ankylosing spondylitis

Dalfampridine

[7] 4-Aminopyridine; 4-AP; AMPYRA; Dalfampridine; FAMPRIDINA; FAMPRIDINE; Fampyra

[1] Dalfampridine 💬

[4] KCNA4,
KCNC3,
KCND2,
KCND3 💬

Name	Full Name
KCNA4	potassium voltage-gated channel subfamily A member 4
KCNC3	potassium voltage-gated channel subfamily C member 3
KCND2	potassium voltage-gated channel subfamily D member 2
KCND3	potassium voltage-gated channel subfamily D member 3

[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬

[5] 3, 4, 6, 13, 14 💬

Hydroxyurea

[1] Hydroxyurea

[1] Hydroxyurea 💬

[1] RRM2 💬

[7] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway 💬

[8] 3, 13, 19, 20, 65, 85, 86, 284 💬

Disease ID	Name
3	Spinal muscular atrophy
13	Multiple sclerosis/Neuromyelitis optica
19	Lysosomal storage disease
20	Adrenoleukodystrophy
65	Primary immunodeficiency
85	Idiopathic interstitial pneumonia
86	Pulmonary arterial hypertension
284	Diamond-Blackfan anemia

Itraconazole

[2] Itraconazole; Sporanox

[1] Itraconazole 💬

[6] 3, 46, 65, 96, 227, 299 💬

Leuprolide

[3] Leuprolide; Leuprolide acetate depot; Leuprorelin

[6] 1, 2, 3, 51, 67, 76 💬

Levocarnitine

[4] Carnitine; L-Carnitine; Levocarnitine; Xyzal

[1] Levocarnitine 💬

[11] 3, 5, 13, 53, 58, 86, 96, 97, 265, 298, 316 💬

Disease ID	Name
3	Spinal muscular atrophy
5	Progressive supranuclear palsy
13	Multiple sclerosis/Neuromyelitis optica
53	Sjogren syndrome
58	Hypertrophic cardiomyopathy
86	Pulmonary arterial hypertension
96	Crohn disease
97	Ulcerative colitis
265	Lipodystrophy
298	Hereditary pancreatitis
316	Carnitine cycle disorder

Midazolam

[2] Midazolam; Midazolam injection

[1] Midazolam 💬

[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬

Name	Full Name
GABRA1	gamma-aminobutyric acid type A receptor subunit alpha1
GABRA2	gamma-aminobutyric acid type A receptor subunit alpha2
GABRA3	gamma-aminobutyric acid type A receptor subunit alpha3
GABRA4	gamma-aminobutyric acid type A receptor subunit alpha4
GABRA5	gamma-aminobutyric acid type A receptor subunit alpha5
GABRA6	gamma-aminobutyric acid type A receptor subunit alpha6
GABRB1	gamma-aminobutyric acid type A receptor subunit beta1
GABRB2	gamma-aminobutyric acid type A receptor subunit beta2
GABRB3	gamma-aminobutyric acid type A receptor subunit beta3
GABRD	gamma-aminobutyric acid type A receptor subunit delta
GABRE	gamma-aminobutyric acid type A receptor subunit epsilon
GABRG1	gamma-aminobutyric acid type A receptor subunit gamma1
GABRG2	gamma-aminobutyric acid type A receptor subunit gamma2
GABRG3	gamma-aminobutyric acid type A receptor subunit gamma3
GABRP	gamma-aminobutyric acid type A receptor subunit pi
GABRQ	gamma-aminobutyric acid type A receptor subunit theta

[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬

[12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
3	Spinal muscular atrophy
6	Parkinson disease
13	Multiple sclerosis/Neuromyelitis optica
21	Mitochondrial disease
46	Malignant rheumatoid arthritis
70	Spinal stenosis
96	Crohn disease
97	Ulcerative colitis
272	Fibrodysplasia ossificans progressiva
298	Hereditary pancreatitis
299	Cystic fibrosis

Nerve Growth Factor

[1] Nerve Growth Factor

[3] 3, 53, 90 💬

Nusinersen

[2] NUSINERSEN; Spinraza

[1] Nusinersen 💬

[1] SMN2 💬

[1] 3 💬

Olesoxime

[1] Olesoxime

[1] Olesoxime 💬

[3] 2, 3, 13 💬

Onasemnogene abeparvovec

[3] ONASEMNOGENE ABEPARVOVEC; Onasemnogene Abeparvovec-xioi; Zolgensma

[1] Onasemnogene abeparvovec 💬

[1] SMN1 💬

[1] 3 💬

Phenylbutyric acid

[4] 4-phenylbutyrate; Pheburane; Phenylbutyrate; Sodium phenylbutyrate

[14] 2, 3, 6, 8, 15, 21, 93, 94, 231, 244, 251, 297, 299, 338 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
3	Spinal muscular atrophy
6	Parkinson disease
8	Huntington disease
15	Inclusion body myositis
21	Mitochondrial disease
93	Primary biliary cholangitis
94	Primary sclerosing cholangitis
231	Alpha-1-antitrypsin deficiency
244	Maple syrup urine disease
251	Urea cycle disorder
297	Alagille syndrome
299	Cystic fibrosis
338	Progressive familial intrahepatic cholestasis

Phosphate ion

[1] Phosphate

[32] 2, 3, 6, 11, 12, 13, 28, 36, 46, 49, 51, 53, 60, 62, 65, 70, 78, 81, 83, 90, 96, 97, 164, 235, 238, 256, 276, 283, 284, 285, 286, 299 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
3	Spinal muscular atrophy
6	Parkinson disease
11	Myasthenia gravis
12	Congenital myasthenic syndrome
13	Multiple sclerosis/Neuromyelitis optica
28	Systemic amyloidosis
36	Epidermolysis bullosa
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
51	Scleroderma
53	Sjogren syndrome
60	Aplastic anemia
62	Paroxysmal nocturnal hemoglobinuria
65	Primary immunodeficiency
70	Spinal stenosis
78	Hypopituitarism
81	Congenital adrenal hyperplasia
83	Addison disease
90	Retinitis pigmentosa
96	Crohn disease
97	Ulcerative colitis
164	Oculocutaneous albinism
235	Hypoparathyroidism
238	Vitamin D-resistant rickets
256	Muscle glycogenosis
276	Achondroplasia
283	Acquired pure red cell aplasia
284	Diamond-Blackfan anemia
285	Fanconi anemia
286	Hereditary sideroblastic anemia
299	Cystic fibrosis

Prednisolone

[3] Prednisolona; Prednisolone; Prednisolonum

[1] Prednisolone 💬

[1] NR3C1 💬

[1] Neuroactive ligand-receptor interaction 💬

[42] 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬

Disease ID	Name
3	Spinal muscular atrophy
11	Myasthenia gravis
13	Multiple sclerosis/Neuromyelitis optica
14	Chronic inflammatory demyelinating polyneuropathy
25	Progressive multifocal leukoencephalopathy
26	HTLV-1-associated myelopathy
35	Pemphigus
38	Stevens-Johnson syndrome
39	Toxic epidermal necrolysis
40	Takayasu arteritis
41	Giant cell arteritis
43	Microscopic polyangiitis
44	Wegener granulomatosis
45	Eosinophilic granulomatosis with Polyangiitis
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
50	Dermatomyositis
51	Scleroderma
56	Behcet disease
60	Aplastic anemia
61	Autoimmune hemolytic anemia
63	Idiopathic thrombocytopenic purpura
64	Thrombotic thrombocytopenic purpura
65	Primary immunodeficiency
66	IgA nephropathy
75	Cushing disease
81	Congenital adrenal hyperplasia
84	Sarcoidosis
85	Idiopathic interstitial pneumonia
95	Autoimmune hepatitis
96	Crohn disease
97	Ulcerative colitis
107	Juvenile idiopathic arthritis
113	Muscular dystrophy
145	West syndrome
162	Pemphigoid
222	Primary nephrotic syndrome
269	Pyogenic arthritis
271	Ankylosing spondylitis
296	Biliary atresia
299	Cystic fibrosis
300	IgG4-related disease

Pyridostigmine

[3] Mestinon; Pyridostigmine; Pyridostigmine Bromide

[4] 3, 6, 11, 256 💬

Reldesemtiv

[2] CK-2127107; RELDESEMTIV

[1] Reldesemtiv 💬

[1] TNNC2 💬

[1] Calcium signaling pathway 💬

[2] 2, 3 💬

Riluzole

[2] RILUTEK; RILUZOLE

[1] Riluzole 💬

[14] GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬

Name	Full Name
GRIA1	glutamate ionotropic receptor AMPA type subunit 1
GRIA2	glutamate ionotropic receptor AMPA type subunit 2
GRIA3	glutamate ionotropic receptor AMPA type subunit 3
GRIA4	glutamate ionotropic receptor AMPA type subunit 4
GRIK1	glutamate ionotropic receptor kainate type subunit 1
GRIK2	glutamate ionotropic receptor kainate type subunit 2
GRIK3	glutamate ionotropic receptor kainate type subunit 3
GRIK4	glutamate ionotropic receptor kainate type subunit 4
GRIK5	glutamate ionotropic receptor kainate type subunit 5
GRIN1	glutamate ionotropic receptor NMDA type subunit 1
GRIN2A	glutamate ionotropic receptor NMDA type subunit 2A
GRIN2B	glutamate ionotropic receptor NMDA type subunit 2B
GRIN2C	glutamate ionotropic receptor NMDA type subunit 2C
GRIN2D	glutamate ionotropic receptor NMDA type subunit 2D

[23] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬

[9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
3	Spinal muscular atrophy
5	Progressive supranuclear palsy
8	Huntington disease
13	Multiple sclerosis/Neuromyelitis optica
17	Multiple system atrophy
18	Spinocerebellar degeneration
203	22q11.2 deletion syndrome
206	Fragile X syndrome

Risdiplam

[2] EVRYSDI; Risdiplam

[1] Risdiplam 💬

[1] SMN2 💬

[1] Nucleocytoplasmic transport 💬

[1] 3 💬

Salbutamol

[3] Albuterol; Salbutamol; Ventolin

[1] Albuterol 💬

[1] ADRB2 💬

[9] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬

[12] 3, 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬

Disease ID	Name
3	Spinal muscular atrophy
11	Myasthenia gravis
12	Congenital myasthenic syndrome
13	Multiple sclerosis/Neuromyelitis optica
49	Systemic lupus erythematosus
85	Idiopathic interstitial pneumonia
86	Pulmonary arterial hypertension
89	Lymphangioleiomyomatosis
111	Congenital myopathy
113	Muscular dystrophy
256	Muscle glycogenosis
299	Cystic fibrosis

Sesame oil

[1] Sesame oil

[1] Sesame oil 💬

[1] 3 💬

Somatotropin

[17] Genotropin; Growth Hormone; Human growth hormone; Humatrope; Norditropin; Norditropin SimpleXx; NUTROPIN; Nutropin AQ; NutropinAq; OMNITROPE; Recombinant human growth hormone; RhGH; SAIZEN; Somatotropin; SOMATROPIN; SOMATROPINA; Zomacton

[25] 2, 3, 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 246, 265, 274, 276, 299, 337 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
3	Spinal muscular atrophy
13	Multiple sclerosis/Neuromyelitis optica
19	Lysosomal storage disease
46	Malignant rheumatoid arthritis
65	Primary immunodeficiency
74	Prolactin secreting pituitary adenoma
75	Cushing disease
76	Pituitary gonadotropin secretion hyperthyroidism
78	Hypopituitarism
96	Crohn disease
107	Juvenile idiopathic arthritis
113	Muscular dystrophy
187	Kabuki syndrome
191	Werner syndrome
193	Prader-Willi syndrome
195	Noonan syndrome
236	Pseudohypoparathyroidism
238	Vitamin D-resistant rickets
246	Methylmalonic acidemia
265	Lipodystrophy
274	Osteogenesis Imperfecta
276	Achondroplasia
299	Cystic fibrosis
337	Homocystinuria

Sulfate ion

[1] Sulfate

[27] 2, 3, 6, 11, 13, 26, 28, 34, 36, 46, 49, 53, 60, 64, 66, 85, 86, 96, 111, 218, 222, 224, 226, 265, 296, 297, 299 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
3	Spinal muscular atrophy
6	Parkinson disease
11	Myasthenia gravis
13	Multiple sclerosis/Neuromyelitis optica
26	HTLV-1-associated myelopathy
28	Systemic amyloidosis
34	Neurofibromatosis
36	Epidermolysis bullosa
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
53	Sjogren syndrome
60	Aplastic anemia
64	Thrombotic thrombocytopenic purpura
66	IgA nephropathy
85	Idiopathic interstitial pneumonia
86	Pulmonary arterial hypertension
96	Crohn disease
111	Congenital myopathy
218	Alport syndrome
222	Primary nephrotic syndrome
224	Purpura nephritis
226	Interstitial cystitis with Hunners ulcer
265	Lipodystrophy
296	Biliary atresia
297	Alagille syndrome
299	Cystic fibrosis

Talditercept alfa

[1] Taldefgrobep alfa

[1] Taldefgrobep alfa 💬

[1] MSTN 💬

[1] Cytokine-cytokine receptor interaction 💬

[1] 3 💬

Testosterone

[1] Testosterone

[1] Testosterone 💬

[1] AR 💬

[4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬

[8] 1, 2, 3, 13, 60, 76, 78, 113 💬

Disease ID	Name
1	Spinal and bulbar muscular atrophy
2	Amyotrophic lateral sclerosis
3	Spinal muscular atrophy
13	Multiple sclerosis/Neuromyelitis optica
60	Aplastic anemia
76	Pituitary gonadotropin secretion hyperthyroidism
78	Hypopituitarism
113	Muscular dystrophy

Valproic acid

[3] Valproate; VALPROATE SODIUM; Valproic Acid

[1] Valproic acid 💬

[7] ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
GAD1,
GAD2 💬

Name	Full Name
ABAT	4-aminobutyrate aminotransferase
ALDH5A1	aldehyde dehydrogenase 5 family member A1
CACNA1G	calcium voltage-gated channel subunit alpha1 G
CACNA1H	calcium voltage-gated channel subunit alpha1 H
CACNA1I	calcium voltage-gated channel subunit alpha1 I
GAD1	glutamate decarboxylase 1
GAD2	glutamate decarboxylase 2

[17] Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬

[14] 2, 3, 5, 6, 13, 26, 65, 85, 90, 102, 127, 222, 233, 256 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
3	Spinal muscular atrophy
5	Progressive supranuclear palsy
6	Parkinson disease
13	Multiple sclerosis/Neuromyelitis optica
26	HTLV-1-associated myelopathy
65	Primary immunodeficiency
85	Idiopathic interstitial pneumonia
90	Retinitis pigmentosa
102	Rubinstein-Taybi syndrome
127	Frontotemporal lobar degeneration
222	Primary nephrotic syndrome
233	Wolfram syndrome
256	Muscle glycogenosis