DR info

Clinical trials : 205 / Drugs : 176 - (DrugBank : 45) / Drug target genes : 61 - Drug target pathways : 127

Cushing disease and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)

ID	Diseases (Sorted by score)	Score
75	Cushing disease	-
96	Crohn disease	22.933
13	Multiple sclerosis/Neuromyelitis optica	19.479
205	Fragile X syndrome related disease	17.290
152	PCDH19 related syndrome	16.000
6	Parkinson disease	15.946
46	Malignant rheumatoid arthritis	14.969
201	Angelman syndrome	14.196
2	Amyotrophic lateral sclerosis	14.151
145	West syndrome	13.742
231	Alpha-1-antitrypsin deficiency	12.976
158	Tuberous sclerosis	12.976
193	Prader-Willi syndrome	12.831
97	Ulcerative colitis	12.689
36	Epidermolysis bullosa	11.982
98	Eosinophilic gastrointestinal disease	11.929
272	Fibrodysplasia ossificans progressiva	11.434
22	Moyamoya disease	10.912
17	Multiple system atrophy	10.894
155	Acquired aphasia with convulsive disorder	10.679
84	Sarcoidosis	10.669
298	Hereditary pancreatitis	10.547
206	Fragile X syndrome	10.459
18	Spinocerebellar degeneration	10.335
21	Mitochondrial disease	10.118
8	Huntington disease	9.677
3	Spinal muscular atrophy	9.564
296	Biliary atresia	9.323
140	Dorabe syndrome	9.031
70	Spinal stenosis	8.710
34	Neurofibromatosis	8.700
144	Lennox-Gastaut syndrome	8.005
5	Progressive supranuclear palsy	7.888
156	Rett syndrome	7.385
74	Prolactin secreting pituitary adenoma	6.855
19	Lysosomal storage disease	6.101
299	Cystic fibrosis	5.406
67	Polycystic kidney disease	5.379
49	Systemic lupus erythematosus	4.492
78	Hypopituitarism	3.519
81	Congenital adrenal hyperplasia	3.290
86	Pulmonary arterial hypertension	2.947
113	Muscular dystrophy	2.480
94	Primary sclerosing cholangitis	2.292
72	Pituitary ADH secretion disorder	2.286
37	Generalised pustular psoriasis	2.206
77	Growth hormone secreting pituitary adenoma	2.000
225	Congenital nephrogenic diabetes insipidus	1.665
233	Wolfram syndrome	1.619
218	Alport syndrome	1.573
187	Kabuki syndrome	1.355
265	Lipodystrophy	1.287
65	Primary immunodeficiency	1.273
64	Thrombotic thrombocytopenic purpura	1.194
51	Scleroderma	1.175
222	Primary nephrotic syndrome	1.114
301	Macular dystrophy	1.097
288	Autoimmune acquired coagulation factor deficiency	1.090
66	IgA nephropathy	1.060
238	Vitamin D-resistant rickets	1.032
235	Hypoparathyroidism	1.032
191	Werner syndrome	1.000
220	Rapidly progressive glomerulonephritis	1.000
30	Distal myopathy	1.000