DR info

Clinical trials : 242 / Drugs : 205 - (DrugBank : 62) / Drug target genes : 85 - Drug target pathways : 159

Huntington disease and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)

ID	Diseases (Sorted by score)	Score
8	Huntington disease	-
6	Parkinson disease	64.162
13	Multiple sclerosis/Neuromyelitis optica	53.890
2	Amyotrophic lateral sclerosis	53.019
46	Malignant rheumatoid arthritis	48.417
206	Fragile X syndrome	44.316
97	Ulcerative colitis	43.315
140	Dorabe syndrome	35.083
17	Multiple system atrophy	34.119
156	Rett syndrome	33.733
144	Lennox-Gastaut syndrome	33.328
96	Crohn disease	33.306
5	Progressive supranuclear palsy	30.643
21	Mitochondrial disease	29.787
18	Spinocerebellar degeneration	27.657
193	Prader-Willi syndrome	25.929
70	Spinal stenosis	24.188
3	Spinal muscular atrophy	22.881
145	West syndrome	22.095
22	Moyamoya disease	18.520
205	Fragile X syndrome related disease	18.480
34	Neurofibromatosis	17.365
201	Angelman syndrome	16.995
152	PCDH19 related syndrome	16.000
113	Muscular dystrophy	15.959
298	Hereditary pancreatitis	15.723
84	Sarcoidosis	15.707
231	Alpha-1-antitrypsin deficiency	14.700
36	Epidermolysis bullosa	14.138
203	22q11.2 deletion syndrome	14.000
158	Tuberous sclerosis	13.469
272	Fibrodysplasia ossificans progressiva	12.306
98	Eosinophilic gastrointestinal disease	12.195
127	Frontotemporal lobar degeneration	10.221
155	Acquired aphasia with convulsive disorder	10.194
86	Pulmonary arterial hypertension	10.139
75	Cushing disease	9.677
296	Biliary atresia	9.514
299	Cystic fibrosis	7.937
78	Hypopituitarism	7.758
4	Primary lateral sclerosis	6.975
85	Idiopathic interstitial pneumonia	6.429
226	Interstitial cystitis with Hunners ulcer	6.286
107	Juvenile idiopathic arthritis	5.474
118	Myelomeningocele	4.607
51	Scleroderma	4.314
49	Systemic lupus erythematosus	4.300
28	Systemic amyloidosis	4.176
149	Hemiconvulsion hemiplegia epilepsy syndrome	4.168
169	Menkes disease	4.143
170	Occipital horn syndrome	4.143
215	Tetralogy of Fallot	3.979
254	Porphyria	3.810
323	Aromatic L-amino acid decarboxylase deficiency	3.000
265	Lipodystrophy	2.989
168	Ehlers-Danlos syndrome	2.910
179	Williams syndrome	2.910
280	Huge arteriovenous malformation with cervicofacial or limb lesion	2.816
271	Ankylosing spondylitis	2.728
1	Spinal and bulbar muscular atrophy	2.649
10	Charcot-Marie-Tooth disease	2.435
288	Autoimmune acquired coagulation factor deficiency	2.286
309	Progressive myoclonus epilepsy	2.277
87	Pulmonary veno-occlusive disease	2.277
88	Chronic thromboembolic pulmonary hypertension	2.106
11	Myasthenia gravis	2.049
256	Muscle glycogenosis	2.032
77	Growth hormone secreting pituitary adenoma	2.000
282	Congenital dyserythropoietic anemia	2.000
120	Hereditary dystonia	2.000
210	Single Ventricle	1.987
58	Hypertrophic cardiomyopathy	1.968
162	Pemphigoid	1.944
90	Retinitis pigmentosa	1.944
38	Stevens-Johnson syndrome	1.865
67	Polycystic kidney disease	1.765
114	Non-dystrophic myotonia syndrome	1.604
65	Primary immunodeficiency	1.405
20	Adrenoleukodystrophy	1.366
187	Kabuki syndrome	1.349
171	Wilson disease	1.349
222	Primary nephrotic syndrome	1.320
212	Tricuspid atresia	1.192
63	Idiopathic thrombocytopenic purpura	1.171
89	Lymphangioleiomyomatosis	1.168
246	Methylmalonic acidemia	1.087
57	Idiopathic dilated cardiomyopathy	1.071
7	Corticobasal degeneration	1.071
91	Budd-Chiari syndrome	1.024
202	Smith-Magenis syndrome	1.024
71	Idiopathic osteonecrosis of the femoral head	1.024
324	Methylglutaconic aciduria	1.000