299. Cystic fibrosis Clinical trials / Disease details

Clinical trials : 1,695 / Drugs : 1,527 - (DrugBank : 268) / Drug target genes : 111 - Drug target pathways : 174

19 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2016-000398-19-BE (EUCTR)	08/03/2016	09/02/2016	Pilot study: pharmacokinetics of beta-lactam antibiotics, piperacillin-tazobactam, ceftazidim and me ...	Pilot study: pharmacokinetics of beta-lactam antibiotics, piperacillin-tazobactam, ceftazidim and me ...	Cystic fibrosis;Therapeutic area: Diseases [C] - Bacterial Infections and Mycoses [C01]	Trade Name: Meropenem Fresenius Kabi 1 g poeder voor oplossing voor injectie of infusie INN or Proposed ...	Ghent University	NULL	Not Recruiting			Female: yes Male: yes	45	Phase 4	Belgium
2	NCT02840136 (ClinicalTrials.gov)	February 2016	18/7/2016	LC-MS/MS Based Method Development for the Monitoring of Antibiotic Concentrations in Sputumof Cystic ...	Optimisation, Valorisation and Application of UPLC-MS/MS Based Monitoring of Antibiotic Concentratio ...	Cystic Fibrosis	Drug: Piperacillin -tazobactam combination product;Drug: Meropenem;Drug: Ceftazidime	University Ghent	King Baudouin Foundation;Belgische Vereniging voor Strijd tegen Mucoviscidose	Suspended	12 Years	N/A	All	40	N/A	Belgium
3	NCT02589444 (ClinicalTrials.gov)	December 2015	20/10/2015	Vitamin D and Microbiota in Cystic Fibrosis	Pilot Study Evaluating the Role of Vitamin D Repletion on Gut and Lung Microbiota in Cystic Fibrosis ...	Vitamin D Deficiency;Cystic Fibrosis	Dietary Supplement: High-Dose Vitamin D3;Other: Stool Sample;Other: SputumSample;Other: Sham Compara ...	Emory University	NULL	Completed	18 Years	N/A	All	41	N/A	United States
4	EUCTR2015-003662-87-DK (EUCTR)	13/11/2015	22/09/2015	Pseudomonas Aeruginosa - Inhalation treatment, biomarkers and quality of life	Pseudomonas Aeruginosa - Inhalation treatment, biomarkers and quality of life - Pseudomonas, Tazocin ...	Chronic pulmonary disease patients, except cystic fibrosis patients, with confirmed pulmonary infect ...	Trade Name: colistimethate sodium (promixin) INN or Proposed INN: COLISTIMETHATE SODIUM Trade Name: Piper ...	Aarhus University Hospital, Department of Respiratory Medicine	NULL	Not Recruiting			Female: yes Male: yes		Phase 2	Denmark
5	NCT02444234 (ClinicalTrials.gov)	July 2015	6/5/2015	Pharmacokinetics of Tedizolid Phosphate in Cystic Fibrosis	Steady-State Pharmacokinetics of Tedizolid in Plasma and Sputum of Patients With Cystic Fibrosis	Cystic Fibrosis	Drug: Tedizolid PO;Drug: Tedizolid IV	University of Southern California	Merck Sharp & Dohme Corp.	Completed	18 Years	N/A	All	11	Phase 4	United States
6	EUCTR2013-004987-80-BE (EUCTR)	28/08/2014	18/02/2014	Colistin dosage through blood samples and sputum in Cystic Fibrosis (CF) population	Colistin use in Cystic Fibrosis patients: pharmacokinetic studies (intravenous administration) in re ...	Colistin use in Cystic Fibrosis patients MedDRA version: 16.1;Level: PT;Classification code 10011762 ...	Trade Name: COLISTINEB 2MUI INN or Proposed INN: Colistineb Other descriptive name: COLISTIMETHATE SODIU ...	CUB - Hôpital Erasme	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes			Belgium
7	NCT01576315 (ClinicalTrials.gov)	June 2014	29/3/2012	ATCF (Azole Therapy in Cystic Fibrosis)	Efficacy of Itraconazole and of Voriconazole in Patients With Cystic Fibrosis and Presenting With Pe ...	Cystic Fibrosis;Aspergillus Infections	Drug: Itraconazole /voriconazole	Rennes University Hospital	NULL	Completed	12 Years	N/A	Both	11	Phase 2	France;United Kingdom
8	EUCTR2011-005799-41-GB (EUCTR)	04/10/2012	21/08/2012	Azole Therapy in Cystic Fibrosis (ATCF)	Azole Therapy in Cystic Fibrosis (ATCF) : Efficacy of itraconazole and ofvoriconazole in patients wi ...	Cystic fibrosis MedDRA version: 14.1;Level: PT;Classification code 10011762;Term: Cystic fibrosis;Sy ...	Trade Name: SPORANOX Product Name: Sporanox 10 mg/ml Oral Solution INN or Proposed INN: ITRACONAZOLE Oth ...	CHU de Rennes (Rennes University Hospital Centre)	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	150		United Kingdom
9	NCT01201434 (ClinicalTrials.gov)	October 2010	31/8/2010	Effect of Probiotics on SputumInflammation and Pulmonary Infections in Patients With Cystic Fibrosis ...	The Effect of Probiotics on SputumBacteria, SputumInflammation, and Pulmonary Infections in Patients ...	Cystic Fibrosis	Dietary Supplement: Bio-25 probiotic	Sheba Medical Center	NULL	Terminated	5 Years	40 Years	Both	12	N/A	NULL
10	NCT02198079 (ClinicalTrials.gov)	March 2010	21/2/2014	A Prospective, Multicenter, Collaborative Study to Determine the Prevalence of Nontuberculous Mycoba ...	A Prospective, Multicenter, Collaborative Study to Determine the Prevalence of Nontuberculous Mycoba ...	Cystic Fibrosis;Pediatrics	Biological: Sputum	University of Miami	University of Florida	Completed	N/A	18 Years	Both	85	N/A	United States

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