6. Parkinson disease Clinical trials / Disease details

Clinical trials : 2,307 / Drugs : 2,007 - (DrugBank : 349) / Drug target genes : 188 - Drug target pathways : 199

235 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05435755 (ClinicalTrials.gov)	December 2, 2022	15/3/2022	Precise Transplantation of hAESCs Into the Ventricle for Parkinson's Disease.	The Precise Transplantation of Human Amniotic Epithelial Stem Cells Into the Ventricle Through Surgi ...	Parkinson's Disease	Biological: hAESCs treatment;Biological: placebo (saline)	Shanghai East Hospital	Shanghai iCELL Biotechnology Co., Ltd, Shanghai, China	Not yet recruiting	30 Years	70 Years	All	12	Early Phase 1	China
2	NCT05696665 (ClinicalTrials.gov)	July 5, 2022	20/12/2022	Role of Saffron and Chamomile in the Management of Parkinson's Disease	Role of Saffron and Chamomile and Their Active Compounds in the Management of Parkinson Disease in t ...	Parkinson Disease;Neurodegenerative Diseases	Other: conventional therapy;Drug: Saffron and Chamomile;Drug: Crocin and Apigenin	Jinnah Postgraduate Medical Centre	Aga Khan University Hospital, Pakistan;Liaquat National Hospital & Medical College	Recruiting	40 Years	85 Years	All	120	N/A	Pakistan
3	JPRN-jRCTs052220012	01/04/2022	22/04/2022	A study of the short-term gait improvement effect using a biological signal reaction type motor func ...	A study of the short-term gait improvement effect using a biological signal reaction type motor func ...	Parkinson's disease Parkinson's disease	The normal rehabilitation group and the HAL grou p are assigned 1: 1 and the normal rehabilitation g ...	Kohara Nobuo	NULL	Recruiting	>= 20age old	Not applicable	Both	30	N/A	Japan
4	ChiCTR2200057481	2022-04-01	2022-03-13	Effect of rotigotine on the quality of recovery in patients with anesthesia awakening after DBS	Effect of rotigotine on the quality of recovery in patients with anesthesia awakening after DBS	Parkinson's disease (PD)	rotigotine group:rotigotine;control group:regular anti-Parkinson's drugs;	First Affiliated Hospital of Zhengzhou University	NULL	Recruiting			Both	rotigotine group:21;control group:21;	N/A	China
5	NCT04858074 (ClinicalTrials.gov)	January 3, 2022	7/4/2021	Study to Investigate the Effect of Hypoestes Rosea Powder in Parkinson's Disease	A Proof of Concept (POC) Study to Investigate the Effect of 100% Hypoestes Rosea Powder in Parkinson ...	Parkinson Disease	Drug: Hypoestoxide	University of Ibadan	NULL	Enrolling by invitation	30 Years	85 Years	All	30	Phase 1/Phase 2	Nigeria
6	NCT04871464 (ClinicalTrials.gov)	November 11, 2021	29/4/2021	Role and Mechanism of Probiotics in Improving Motor Symptoms in Mild to Moderate Parkinson's Disease ...	Role and Mechanism of Bifidobacterium Triple Viable Capsules in Improving Motor Symptoms in Patients ...	Parkinson Disease;Parkinsonian Disorders;Basal Ganglia Diseases;Brain Diseases;Movement Disorders;Ne ...	Drug: Live Combined Bifidobacterium,Lactobacillus and Enterococcus Capsules;Other: Placebo	Beijing Friendship Hospital	NULL	Recruiting	40 Years	85 Years	All	240	Phase 4	China
7	EUCTR2020-004997-23-PL (EUCTR)	09/06/2021	03/09/2021	A Study to Evaluate the Efficacy and Safety of Intravenous Prasinezumab in Participants with Early P ...	A PHASE IIB, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTICENTER STUDY TO EVALUATE THE EFFICAC ...	Early Parkinson's disease MedDRA version: 20.0;Level: PT;Classification code 10061536;Term: Parkinso ...	Product Name: aSyn Mab Product Code: RO7046015 INN or Proposed INN: Prasinezumab Other descriptive name ...	F. Hoffmann-La Roche Ltd	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	575	Phase 2	France;United States;Canada;Spain;Poland;Austria;United Kingdom;Italy
8	EUCTR2020-004997-23-AT (EUCTR)	27/05/2021	16/03/2021	A Study to Evaluate the Efficacy and Safety of Intravenous Prasinezumab in Participants with Early P ...	A PHASE IIB, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTICENTER STUDY TO EVALUATE THE EFFICAC ...	Early Parkinson's disease MedDRA version: 20.0;Level: PT;Classification code 10061536;Term: Parkinso ...	Product Name: aSyn Mab Product Code: RO7046015 INN or Proposed INN: Prasinezumab Other descriptive name ...	F. Hoffmann-La Roche Ltd	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	575	Phase 2	Austria;United Kingdom;Italy;France;United States;Canada;Spain;Poland
9	EUCTR2020-004997-23-ES (EUCTR)	25/05/2021	01/09/2021	A Study to Evaluate the Efficacy and Safety of Intravenous Prasinezumab in Participants with Early P ...	A PHASE IIB, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTICENTER STUDY TO EVALUATE THE EFFICAC ...	Early Parkinson's disease MedDRA version: 20.0;Level: PT;Classification code 10061536;Term: Parkinso ...	Product Name: aSyn Mab Product Code: RO7046015 INN or Proposed INN: Prasinezumab Other descriptive name ...	Roche Farma S. A. U. que realiza el ensayo en España y que actúa como representante F. Hoffmann-La R ...	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	575	Phase 2	France;United States;Canada;Poland;Spain;Austria;United Kingdom;Italy
10	NCT04346394 (ClinicalTrials.gov)	May 11, 2021	10/3/2020	The Role of the Noradrenergic System in the Nonmotor Symptoms of Parkinson's Disease	The Role of the Noradrenergic System in the Nonmotor Symptoms of Parkinson's Disease: Orthostatic Hy ...	Parkinson Disease	Drug: Yohimbine HCl	Nathaniel M. Robbins	NULL	Suspended	N/A	N/A	All	22	Early Phase 1	United States

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