60. Aplastic anemia Clinical trials / Disease details

Clinical trials : 245 / Drugs : 318 - (DrugBank : 86) / Drug target genes : 44 - Drug target pathways : 166

11 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03579875 (ClinicalTrials.gov)	November 13, 2018	25/5/2018	T Cell Receptor a/ß TCD HCT in Patients With Fanconi Anemia	T Cell Receptor Alpha/Beta T Cell Depleted (a/ß TCD) Hematopoietic Cell Transplantation in Patients ...	Fanconi Anemia;Severe Aplastic Anemia;Myelodysplastic Syndromes	Drug: Total Body Irradiation (TBI) (Plan 1);Drug: Cyclophosphamide (CY) (Plan 1);Drug: Fludarabine (FL ...	Masonic Cancer Center, University of Minnesota	NULL	Recruiting	N/A	65 Years	All	48	Phase 2	United States
2	ChiCTR1900023509	2017-01-01	2019-05-31	Allogeneic Hematopoietic Stem Cell Transplantation with Risk-adapted Conditioning Regimens for Child ...	Allogeneic Hematopoietic Stem Cell Transplantation with Risk-adapted Conditioning Regimens for Child ...	aplastic anemia,Refractory Cytopenia of Childhood	1:Fludarabine150 mg/m2 +Cyclophosphamide200 mg/kg+ Thymoglobuline10mg/kg;2:Fludarabine200 mg/m2 +Cyc ...	Shanghai Children's Medical Center affiliated to Shanghai Jiao Tong University School of Medicine	NULL	Recruiting		18	Both	1:50;2:50;3:50;		China
3	NCT01760655 (ClinicalTrials.gov)	December 24, 2012	2/1/2013	Reduced-Intensity Conditioning Before Donor Stem Cell Transplant in Treating Patients With High-Risk ...	A Two Step Approach to Reduced Intensity Allogeneic Hematopoietic Stem Cell Transplantation for High ...	Acute Myeloid Leukemia With FLT3/ITD Mutation;Acute Myeloid Leukemia With Gene Mutations;Acute Myelo ...	Drug: Fludarabine phosphate;Drug: Busulfan;Radiation: Total-Body Irradiation;Biological: Therapeutic ...	Sidney Kimmel Cancer Center at Thomas Jefferson University	National Cancer Institute (NCI)	Completed	N/A	N/A	All	62	Phase 2	United States
4	NCT01500161 (ClinicalTrials.gov)	November 2011	18/11/2011	Pooled Unrelated Donor Umbilical Cord Blood Transplant For Hematologic Malignancy Needing Allogeneic ...	A Phase II Study Of Pooled Unrelated Donor Umbilical Cord Blood (UCB) Transplant For Patients With H ...	Acute Myelogenous Leukemia;Acute Lymphocytic Leukemia;Chronic Lymphocytic Leukemia;Chronic Myelogeno ...	Drug: Busulfan;Drug: Clofarabine;Drug: Fludarabine;Drug: Melphalan;Drug: Carmustine;Drug: Etoposide; ...	Texas Oncology Cancer Center	NULL	Terminated	18 Years	65 Years	Both	1	Phase 2	United States
5	NCT01384513 (ClinicalTrials.gov)	August 4, 2011	27/6/2011	A Two-Step Approach to Reduced Intensity Bone Marrow Transplant for Patients With Hematological Mali ...	A Two Step Approach to Reduced Intensity Allogeneic Hematopoietic Stem Cell Transplantation for Pati ...	Adult Acute Myeloid Leukemia With Inv(16)(p13;q22);Adult Acute Myeloid Leukemia With t(15;17)(q22;q1 ...	Drug: Fludarabine;Drug: Busulfan;Radiation: Total Body Irradiation (TBI);Biological: Donor Lymphocyt ...	Sidney Kimmel Cancer Center at Thomas Jefferson University	NULL	Completed	18 Years	N/A	All	40	Phase 2	United States
6	NCT00987480 (ClinicalTrials.gov)	September 25, 2009	30/9/2009	Hematopoietic Stem Cell Transplantation for the Treatment of Patients With Fanconi Anemia Lacking a ...	A Multicenter Phase II Trial of Hematopoietic Stem Cell Transplantation for the Treatment of Patient ...	Aplastic Anemia;Leukemia;Myelodysplastic Syndrome	Drug: Busulfan , fludarabine, & cyclophosphamide with immunosuppression with ATG and cyclosporine.;De ...	Memorial Sloan Kettering Cancer Center	Boston Children's Hospital;Children's Hospital Medical Center, Cincinnati;Children's Hospital and He ...	Completed	N/A	N/A	All	45	Phase 2	United States
7	EUCTR2007-001657-26-GB (EUCTR)	29/02/2008	07/11/2007	Single Centre Phase II Pilot study of Unrelated Cord Blood Transplantation in Patients with Poor Ris ...	Single Centre Phase II Pilot study of Unrelated Cord Blood Transplantation in Patients with Poor Ris ...	1.Acute, chronic leukaemia or myelodysplastic syndrome for which allogeneic transplantation is consi ...	Trade Name: Fludarabine INN or Proposed INN: FLUDARABINE PHOSPHATE Trade Name: Busilvex INN or Proposed ...	King's College Hospital NHS Foundation Trust	NULL	Not Recruiting			Female: yes Male: yes	27	Phase 2	United Kingdom
8	NCT00295997 (ClinicalTrials.gov)	May 2005	23/2/2006	Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer, Metastatic Kidney Cancer, o ...	Non-myeloablative Allogeneic Stem Cell Transplantation With Match Unrelated Donors for Treatment of ...	Chronic Myeloproliferative Disorders;Kidney Cancer;Leukemia;Lymphoma;Multiple Myeloma and Plasma Cel ...	Biological: anti-thymocyte globulin;Biological: filgrastim;Biological: graft-versus-tumor induction ...	University of California, San Francisco	National Cancer Institute (NCI)	Active, not recruiting	N/A	74 Years	Both	35	N/A	United States
9	NCT00516152 (ClinicalTrials.gov)	November 2002	13/8/2007	Phase II Study Evaluating Busulfanand Fludarabine as Preparative Therapy in Adults With Hematopoieti ...	Phase II Study Evaluating Busulfanand Fludarabine as Preparative Therapy in Adults With Hematopoieti ...	Chronic Myeloid Leukemia;Acute Myelogenous Leukemia;Myelodysplasia;Acute Lymphocytic Leukemia;Severe ...	Drug: Busulfan /Fludarabine phosphate/Tacrolimus/Methotrexate/G-CSF	University of California, San Francisco	NULL	Completed	15 Years	61 Years	Both	36	Phase 2	United States
10	NCT00003816 (ClinicalTrials.gov)	October 19, 1998	1/11/1999	Combination Chemotherapy and Donor Stem Cell Transplant in Treating Patients With Aplastic Anemia or ...	Allogeneic Blood or Marrow Transplantation for Hematologic Malignancy and Aplastic Anemia	Chronic Myeloproliferative Disorders;Leukemia;Lymphoma;Myelodysplastic Syndromes;Myelodysplastic/Mye ...	Biological: anti-thymocyte globulin;Drug: busulfan;Drug: carboplatin;Drug: cyclophosphamide;Drug: et ...	Roswell Park Cancer Institute	NULL	Completed	4 Years	70 Years	All	362	Phase 2/Phase 3	United States

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