60. Aplastic anemia Clinical trials / Disease details

Clinical trials : 245 / Drugs : 318 - (DrugBank : 86) / Drug target genes : 44 - Drug target pathways : 166

16 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03579875 (ClinicalTrials.gov)	November 13, 2018	25/5/2018	T Cell Receptor a/ß TCD HCT in Patients With Fanconi Anemia	T Cell Receptor Alpha/Beta T Cell Depleted (a/ß TCD) Hematopoietic Cell Transplantation in Patients ...	Fanconi Anemia;Severe Aplastic Anemia;Myelodysplastic Syndromes	Drug: Total Body Irradiation (TBI) (Plan 1);Drug: Cyclophosphamide (CY) (Plan 1);Drug: Fludarabine (FL ...	Masonic Cancer Center, University of Minnesota	NULL	Recruiting	N/A	65 Years	All	48	Phase 2	United States
2	NCT02918292 (ClinicalTrials.gov)	July 3, 2017	27/9/2016	Optimizing Haploidentical Aplastic Anemia Transplantation (BMT CTN 1502)	Optimizing Haploidentical Aplastic Anemia Transplantation (CHAMP) (BMT CTN 1502)	Severe Aplastic Anemia	Drug: Antithymocyte Globulin (ATG);Drug: Fludarabine;Drug: Cyclophosphamide;Radiation: Total Body Ir ...	Medical College of Wisconsin	National Heart, Lung, and Blood Institute (NHLBI);National Cancer Institute (NCI);Blood and Marrow T ...	Completed	N/A	75 Years	All	32	Phase 2	United States
3	NCT02960646 (ClinicalTrials.gov)	January 18, 2017	8/11/2016	Engineered Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies	Phase I Clinical Trial Using an Engineered Peripheral Blood Graft for Haploidentical Transplantation ...	Acute Lymphoblastic Leukemia;Acute Myeloid Leukemia;Acute Myeloid Leukemia Arising From Previous Mye ...	Drug: Cyclophosphamide;Biological: Filgrastim;Drug: Fludarabine Phosphate;Other: Laboratory Biomarker ...	M.D. Anderson Cancer Center	National Cancer Institute (NCI)	Completed	18 Years	65 Years	All	11	Phase 1	United States
4	NCT01759732 (ClinicalTrials.gov)	September 2012	30/12/2012	Haploidentical Stem Cell Transplantation for Children With Acquired Severe Aplastic Anemia	Haploidentical Stem Cell Transplantation With Fixed Dose of T Cells After in Vitro T Cell Depletion ...	Acquired Aplastic Anemia	Drug: Fludarabine;Drug: Cyclophosphamide;Biological: anti-thymocyte globulin;Biological: filgrastim; ...	Asan Medical Center	NULL	Recruiting	N/A	21 Years	Both	10	Phase 2	Korea, Republic of
5	NCT01624805 (ClinicalTrials.gov)	June 25, 2012	19/6/2012	Methylprednisolone, Horse Anti-Thymocyte Globulin, Cyclosporine, Filgrastim, and/or Pegfilgrastim or ...	Phase II Study of Horse Anti-Thymocyte Globulin (hATG), Cyclosporine, Methylprednisolone, and GCSF ( ...	Aplastic Anemia;de Novo Myelodysplastic Syndrome;Myelodysplastic Syndrome;Previously Treated Myelody ...	Biological: Anti-Thymocyte Globulin;Drug: Cyclosporine;Biological: Filgrastim;Drug: Methylprednisolo ...	M.D. Anderson Cancer Center	National Cancer Institute (NCI)	Recruiting	N/A	N/A	All	100	Phase 2	United States
6	NCT01105273 (ClinicalTrials.gov)	July 2009	8/4/2010	Human Leukocyte Antigen (HLA)-Haploidentical Hematopoietic Stem Cell Transplantation for Patients Wi ...	HLA-haploidentical Allogeneic Hematopoietic Cell Transplantation Using CD3±CD19 Depletion for Patien ...	Aplastic Anemia	Biological: anti-thymocyte globulin;Biological: filgrastim;Drug: Fludarabine;Drug: Cyclophosphamide; ...	Asan Medical Center	NULL	Completed	N/A	21 Years	Both	12	Phase 1/Phase 2	Korea, Republic of
7	NCT00354419 (ClinicalTrials.gov)	February 2006	19/7/2006	Cyclophosphamide, Antithymocyte Globulin, and Total-Body Irradiation in Treating Patients With Sever ...	A Dose Finding Study of Total Body Irradiation for Conditioning Patients With Severe Aplastic Anemia ...	Aplastic Anemia	Radiation: total-body irradiation;Drug: cyclophosphamide;Biological: anti-thymocyte globulin;Drug: c ...	Fred Hutchinson Cancer Research Center	National Cancer Institute (NCI)	Terminated	N/A	40 Years	Both	30	Phase 1	United States
8	NCT00806598 (ClinicalTrials.gov)	May 2005	9/12/2008	Thymoglobulin and Cyclosporine in Patients With Aplastic Anemia or Myelodysplastic Syndrome	Phase II Study of Combination of Thymoglobulin, Cyclosporine, Methylprednisone, and Granulocyte Colo ...	Myelodysplastic Syndrome;Aplastic Anemia	Drug: Thymoglobulin;Drug: Cyclosporine;Drug: Methylprednisolone;Drug: G-CSF	M.D. Anderson Cancer Center	Genzyme, a Sanofi Company	Completed	15 Years	N/A	All	53	Phase 2	United States
9	NCT00295997 (ClinicalTrials.gov)	May 2005	23/2/2006	Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer, Metastatic Kidney Cancer, o ...	Non-myeloablative Allogeneic Stem Cell Transplantation With Match Unrelated Donors for Treatment of ...	Chronic Myeloproliferative Disorders;Kidney Cancer;Leukemia;Lymphoma;Multiple Myeloma and Plasma Cel ...	Biological: anti-thymocyte globulin;Biological: filgrastim;Biological: graft-versus-tumor induction ...	University of California, San Francisco	National Cancer Institute (NCI)	Active, not recruiting	N/A	74 Years	Both	35	N/A	United States
10	NCT00054236 (ClinicalTrials.gov)	May 2002	5/2/2003	Combination Chemotherapy Followed By Umbilical Cord Blood Transplantation in Treating Patients With ...	Pilot Study Of Multiple Umbilical Cord Blood Unit Transplantation Following Non-Myeloablative Condit ...	Chronic Myeloproliferative Disorders;Leukemia;Lymphoma;Multiple Myeloma and Plasma Cell Neoplasm;Mye ...	Biological: anti-thymocyte globulin;Biological: filgrastim;Drug: cyclophosphamide;Drug: fludarabine p ...	Case Comprehensive Cancer Center	NULL	Completed	N/A	120 Years	All	55	Phase 1	United States

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