65. Primary immunodeficiency Clinical trials / Disease details

Clinical trials : 500 / Drugs : 614 - (DrugBank : 119) / Drug target genes : 92 - Drug target pathways : 217

9 trials found

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Showing 1 to 9 of 9 diseases

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05463133 (ClinicalTrials.gov)	July 8, 2022	15/7/2022	Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Granulomatous Disease (CGD) With an A ...	Phase I/II Study Using Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Granulomatous ...	Chronic Granulomatous Disease	Drug: Sirolimus;Drug: Cyclophosphamide;Drug: Alemtuzumab;Drug: Busulfan;Biological: Pheripheral bloo ...	National Institute of Allergy and Infectious Diseases (NIAID)	NULL	Recruiting	4 Years	65 Years	All	50	Phase 1/Phase 2	United States
2	NCT04339777 (ClinicalTrials.gov)	September 22, 2020	8/4/2020	Allogeneic Hematopoietic Stem Cell Transplant for Patients With Inborn Errors of Immunity	A Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Patients With Inborn Errors of ...	Lymphoproliferative Disorders;Autoimmune Lymphoproliferative;Immune System Diseases;Common Variable ...	Drug: Busulfan test dose;Drug: Fludarabine;Drug: Busulfan;Drug: Alemtuzumab;Radiation: Total body Irr ...	National Cancer Institute (NCI)	NULL	Recruiting	4 Years	69 Years	All	66	Phase 2	United States
3	NCT03910452 (ClinicalTrials.gov)	October 28, 2019	9/4/2019	Haploidentical Transplant for People With Chronic Granulomatous Disease (CGD) Using Alemtuzumab, Bus ...	Haploidentical Transplant for Patients With Chronic Granulomatous Disease (CGD) Using Alemtuzumab, B ...	Chronic Granulomatous Disease	Drug: Busulfan;Drug: Alemtuzumab;Drug: Cyclophosphamide;Drug: Sirolimus;Radiation: Total Body Irradi ...	National Institute of Allergy and Infectious Diseases (NIAID)	NULL	Recruiting	4 Years	65 Years	All	30	Early Phase 1	United States
4	NCT03333486 (ClinicalTrials.gov)	December 7, 2017	2/11/2017	Fludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in T ...	A Phase II Trial of Haploidentical Allogeneic Stem Cell Transplantation Utilizing Mobilized Peripher ...	Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive;Acute Leukemia in Remission;Acute ...	Drug: Cyclophosphamide;Drug: Fludarabine Phosphate;Other: Laboratory Biomarker Analysis;Procedure: Pe ...	Roswell Park Cancer Institute	NULL	Active, not recruiting	1 Year	75 Years	All	31	Phase 2	United States
5	NCT02629120 (ClinicalTrials.gov)	December 17, 2015	10/12/2015	High Dose Peripheral Blood Stem Cell Transplantation With Post Transplant Cyclophosphamide for Patie ...	High Dose Peripheral Blood Stem Cell Transplantation With Post Transplant Cyclophosphamide for Patie ...	Chronic Granulomatous Disease Transplant	Drug: Alemtuzumab;Drug: Busulfan;Drug: Sirolimus;Drug: Cyclophosphamide;Radiation: Total Body Irradi ...	National Institute of Allergy and Infectious Diseases (NIAID)	NULL	Active, not recruiting	4 Years	65 Years	All	44	Phase 1/Phase 2	United States
6	NCT02162420 (ClinicalTrials.gov)	January 10, 2015	10/6/2014	Hematopoietic Stem Cell Transplant for Dyskeratosis Congenita or Severe Aplastic Anemia	Hematopoietic Stem Cell Transplant for Dyskeratosis Congenita or Severe Aplastic Anemia	Dyskeratosis Congenita;Aplastic Anemia	Drug: Alemtuzumab;Drug: Fludarabine;Drug: Cyclophosphamide;Radiation: Total Body Irradiation;Biologi ...	Masonic Cancer Center, University of Minnesota	NULL	Recruiting	0 Years	70 Years	All	50	N/A	United States
7	NCT01529827 (ClinicalTrials.gov)	February 28, 2012	6/2/2012	Fludarabine Phosphate, Melphalan, and Low-Dose Total-Body Irradiation Followed by Donor Peripheral B ...	A Phase II Trial of Reduced Intensity Allogeneic Stem Cell Transplantation With Fludarabine, Melphal ...	Accelerated Phase Chronic Myelogenous Leukemia;Adult Acute Lymphoblastic Leukemia in Remission;Adult ...	Drug: fludarabine phosphate;Drug: melphalan;Radiation: total-body irradiation;Drug: tacrolimus;Drug: ...	Roswell Park Cancer Institute	NULL	Completed	3 Years	75 Years	All	94	Phase 2	United States
8	NCT00455312 (ClinicalTrials.gov)	August 2007	30/3/2007	Stem Cell Transplant (SCT) for Dyskeratosis Congenita or SAA	Hematopoietic Stem Cell Transplant For Patients With Dyskeratosis Congenita and Severe Aplastic Anem ...	Dyskeratosis Congenita;Aplastic Anemia	Drug: Campath 1H;Drug: Cyclophosphamide;Drug: Fludarabine;Procedure: Total Body Irradiation;Procedure ...	Masonic Cancer Center, University of Minnesota	NULL	Completed	N/A	70 Years	All	36	Phase 2/Phase 3	United States
9	NCT00176852 (ClinicalTrials.gov)	June 2002	12/9/2005	Stem Cell Transplant for Hemoglobinopathy	Allogeneic Hematopoietic Stem Cell Transplant for Patients With High Risk Hemoglobinopathy Using a P ...	Sickle Cell Disease;Thalassemia;Severe Congenital Neutropenia;Diamond-Blackfan Anemia;Shwachman-Diam ...	Drug: Busulfan , Fludarabine, ATG, TLI;Drug: Busulfan , Cyclophosphamide, ATG, GCSF;Drug: Campath, Flu ...	Masonic Cancer Center, University of Minnesota	National Marrow Donor Program	Completed	N/A	50 Years	All	22	Phase 2/Phase 3	United States

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