Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Acetaminophen
(Synonym: Otis Clapp Back Quell)		[5] Acetaminophen; Oxycodone/Acetaminophen; Paracetamol; Tylenol; Ultracet[1] D00217 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[18] 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337
2 Acetic acid
(Synonym: Star-otic Solution)		[1] Acetic acid[1] D00010 --[1] 97
3 Allantoin
(Synonym: Inflammation OTC Radiation Relief)		[1] ALLANTOIN[1] D00121 --[1] 36
4 Aloe vera leaf
(Synonym: C Ottways Lax Tab)		[3] Aloe; Aloe vera; Aloe vera gel---[3] 53, 97, 226
5 Apremilast
(Synonym: Otezla)		[2] Apremilast; Otezla[1] D08860 (Name: Otezla (TN))[4] PDE4A,
PDE4B,
PDE4C,
PDE4D 💬		[5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬[7] 46, 50, 56, 97, 107, 162, 271
6 Betamethasone
(Synonym: Betamycin Ophthalmic/otic Solution)		[1] Betamethasone[7] D00244 ,
D00972 ,
D01357 ,
D01402 ,
D01637 ,
D02032 ,
D02286 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[7] 2, 28, 46, 83, 90, 96, 235
7 Calcium carbonate
(Synonym: Relief OTC antacid)		[3] Calcio carbonato; Calcium; Calcium carbonate[2] D00932 ,
D10802 		--[9] 13, 19, 46, 53, 75, 96, 235, 274, 299
8 Capsaicin
(Synonym: Pallerix OTC BIOfrequency Chip)		[2] Capsaicin; Qutenza[1] D00250 [1] TRPV1 💬[2] Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[5] 2, 6, 19, 86, 226
9 Chlorpheniramine
(Synonym: Otis Clapp Valihist)		[1] Clorfenamina[4] D00665 ,
D00668 ,
D07398 ,
D07803 		[1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[1] 14
10 Ciprofloxacin
(Synonym: Otixal)		[2] CIPROFLOXACIN; CIPROFLOXACIN HYDROCHLORIDE[2] D00186 (Name: Otiprio (TN)),
D02216 (Name: CIPROFLOXACIN OTIC)		--[5] 2, 60, 96, 97, 299
11 Ethanol
(Synonym: hand sanitizer OTC)		[3] Alcohol; Ethanol; Prednisone[4] D00068 ,
D02798 ,
D04855 ,
D06542 		--[7] 13, 51, 58, 97, 279, 280, 298
12 Fluocinolone acetonide
(Synonym: Flac Otic Oil)		[2] Fluocinolone Acetonide; Iluvien[1] D01825 (Name: FLAC OTIC OIL)[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 90
13 Gentamicin
(Synonym: Garatec Otic Dps 5mg/ml)		[2] Gentamicin; Gentamicin Sulfate[2] D01063 ,
D08013 		--[3] 36, 113, 299
14 Ginger
(Synonym: C Ottways Lax Tab)		[1] Ginger[1] D06744 --[2] 46, 271
15 Glycyrrhiza glabra
(Synonym: C Ottways Lax Tab)		[3] Glycyrrhiza; Glycyrrhiza glabra; GLYCYRRHIZA GLABRA ROOT---[2] 53, 97
16 Hydrocortisone
(Synonym: Cipro HC Otic Suspension)		[6] Cortef; Cortisol; Cortisone; Hydrocortisone; Hydrocortisone cream; Hydrocortisonum[1] D00088 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[11] 6, 41, 46, 53, 75, 78, 81, 83, 97, 98, 299
17 Hydrocortisone acetate
(Synonym: Otizol HC Liq)		[2] Hydrocortisone; HYDROCORTISONE ACETATE[1] D00165 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 97
18 Ibuprofen
(Synonym: Otis Clapp Ultraprin)		[2] Ibuprofen; IBUPROFEN 200MG[4] D00126 ,
D01122 ,
D04490 ,
D06606 		[2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[7] 13, 46, 65, 107, 113, 271, 299
19 Lidocaine
(Synonym: Otizol HC Liq)		[4] Aloe; Lidocaine; Lignocaine; Xylocaine[3] D00358 ,
D02086 ,
D08127 		[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[13] 6, 13, 34, 46, 51, 70, 84, 86, 107, 168, 226, 231, 256
20 Methotrexate
(Synonym: Otrexup)		[6] Methotrexat; Methotrexate; METHOTREXATE SODIUM; METOJECT; METOTREXATO; Méthotrexate[2] D00142 (Name: Otrexup (TN)),
D02115 		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331
21 Neomycin
(Synonym: Otizol HC Liq)		[1] Neomycin[1] D08260 --[3] 96, 97, 296
22 Omeprazole
(Synonym: Prilosec OTC)		[5] Losec; Omeprazol; Omeprazole; Omeprazole 20 mg; OMEPRAZOLE MAGNESIUM[4] D00455 ,
D01207 ,
D05259 (Name: Prilosec OTC (TN)),
D05261 		[2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[16] 6, 8, 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299
23 Otelixizumab [1] Otelixizumab[1] D08959 (Name: Otelixizumab)[3] CD3D,
CD3E,
CD3G 💬		[11] Chagas disease, Epstein-Barr virus infection, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human immunodeficiency virus 1 infection, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬[1] 46
24 Otilimab [1] Otilimab[1] D11343 (Name: Otilimab)[1] CSF2 💬[16] Acute myeloid leukemia, Amoebiasis, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, IL-17 signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Natural killer cell mediated cytotoxicity, Rheumatoid arthritis, Shigellosis, T cell receptor signaling pathway, TNF signaling pathway, Transcriptional misregulation in cancer 💬[2] 46, 256
25 Phenylephrine
(Synonym: Ortizol Otic Solution)		[1] Phenylephrine[2] D00511 ,
D08365 		[3] ADRA1A,
ADRA1B,
ADRA1D 💬		[7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 22
26 Senna leaf
(Synonym: C Ottways Lax Tab)		[1] Senna[1] D06751 --[1] 291
27 Sodium bicarbonate
(Synonym: Zegerid OTC)		[1] Sodium Bicarbonate[1] D01203 --[1] 299
28 Zinc acetate
(Synonym: Otozin)		[2] Wilzin; Zinc acetate[1] D06408 --[2] 171, 299