Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank 薬物名（臨床試験情報から抽出） KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Anhydrous lactose 💬1件: Lactose1件: Lactose--5件: 2, 6, 21, 228, 310 💬
2 Arginine 💬1件: Arginine1件: Arginine--3件: 72, 225, 251 💬
3 Arginine hydrochloride 💬1件: Arginine1件: Arginine--3件: 72, 225, 251 💬
4 Arginine hydrochloride 💬1件: Arginine1件: Arginine--3件: 72, 225, 251 💬
5 Bupropion 💬1件: Bupropion2件: Bupropion; Bupropion hydrochloride2件: SLC6A2,
SLC6A3 💬 		8件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Neuroactive ligand signaling, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬4件: 8, 21, 96, 171 💬
6 Bupropion hydrobromide 💬1件: Bupropion2件: Bupropion; Bupropion hydrochloride2件: SLC6A2,
SLC6A3 💬 		8件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Neuroactive ligand signaling, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬4件: 8, 21, 96, 171 💬
7 Bupropion hydrochloride 💬1件: Bupropion2件: Bupropion; Bupropion hydrochloride2件: SLC6A2,
SLC6A3 💬 		8件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Neuroactive ligand signaling, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬4件: 8, 21, 96, 171 💬
8 Caffeine 💬1件: Caffeine1件: Caffeine11件: ADORA1,
ADORA2A,
PDE1,
PDE2A,
PDE3A,
PDE3B,
PDE4,
PDE4,
PDE4,
PDE4,
PDE5 💬 		22件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬8件: 2, 6, 13, 21, 46, 96, 97, 265 💬
9 Caffeine citrate 💬1件: Caffeine1件: Caffeine11件: ADORA1,
ADORA2A,
PDE1,
PDE2A,
PDE3A,
PDE3B,
PDE4,
PDE4,
PDE4,
PDE4,
PDE5 💬 		22件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬8件: 2, 6, 13, 21, 46, 96, 97, 265 💬
10 Caffeine hydrate 💬1件: Caffeine1件: Caffeine11件: ADORA1,
ADORA2A,
PDE1,
PDE2A,
PDE3A,
PDE3B,
PDE4,
PDE4,
PDE4,
PDE4,
PDE5 💬 		22件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬8件: 2, 6, 13, 21, 46, 96, 97, 265 💬
11 Cysteamine 💬1件: Cysteamine6件: 2-aminoethanethiol; Cysteamine; Cysteamine bitartrate; Cysteamine hydrochloride; Mercaptamina; Mercaptamine--4件: 8, 19, 21, 299 💬
12 Cysteamine bitartrate 💬1件: Cysteamine6件: 2-aminoethanethiol; Cysteamine; Cysteamine bitartrate; Cysteamine hydrochloride; Mercaptamina; Mercaptamine--4件: 8, 19, 21, 299 💬
13 Cysteamine hydrochloride 💬1件: Cysteamine6件: 2-aminoethanethiol; Cysteamine; Cysteamine bitartrate; Cysteamine hydrochloride; Mercaptamina; Mercaptamine--4件: 8, 19, 21, 299 💬
14 Daunorubicin 💬1件: Dextromethorphan2件: Dextromethorphan; Dextromethorphan hydrobromide--9件: 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
15 Dexmedetomidine 💬1件: Dexmedetomidine3件: Dexmedetomidina; Dexmedetomidine; Dexmedetomidine hydrochloride3件: ADRA2A,
ADRA2B,
ADRA2C 💬 		4件: Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬15件: 2, 4, 6, 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
16 Dexmedetomidine hydrochloride 💬1件: Dexmedetomidine3件: Dexmedetomidina; Dexmedetomidine; Dexmedetomidine hydrochloride3件: ADRA2A,
ADRA2B,
ADRA2C 💬 		4件: Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬15件: 2, 4, 6, 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
17 Dextromethorphan 💬1件: Dextromethorphan2件: Dextromethorphan; Dextromethorphan hydrobromide6件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬 		21件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬9件: 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
18 Dextromethorphan hydrobromide 💬1件: Dextromethorphan2件: Dextromethorphan; Dextromethorphan hydrobromide6件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬 		21件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬9件: 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
19 Elamipretide 💬1件: Elamipretide1件: Elamipretide--3件: 18, 21, 324 💬
20 Elamipretide hydrochloride 💬1件: Elamipretide1件: Elamipretide--3件: 18, 21, 324 💬
21 Flurbiprofen 💬1件: Flurbiprofen1件: Flurbiprofen2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬3件: 13, 21, 46 💬
22 Flurbiprofen sodium 💬1件: Flurbiprofen1件: Flurbiprofen2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬3件: 13, 21, 46 💬
23 Glutamine 💬1件: L-Glutamine2件: Glutamine; L-glutamine--10件: 87, 89, 96, 97, 113, 214, 215, 222, 245, 299 💬
24 Glycerin 💬1件: Glycerin1件: Glycerol--1件: 79 💬
25 Idebenone 💬1件: Idebenone1件: Idebenone--7件: 6, 8, 13, 18, 21, 113, 302 💬
26 Lactose 💬1件: Lactose1件: Lactose--5件: 2, 6, 21, 228, 310 💬
27 Midazolam 💬1件: Midazolam1件: Midazolam16件: GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRB,
GABRB,
GABRB,
GABRD,
GABRE,
GABRG,
GABRG,
GABRG,
GABRP,
GABRQ 💬 		8件: GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬12件: 2, 3, 6, 13, 46, 67, 96, 97, 231, 272, 298, 299 💬
28 Midazolam hydrochloride 💬1件: Midazolam1件: Midazolam16件: GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRB,
GABRB,
GABRB,
GABRD,
GABRE,
GABRG,
GABRG,
GABRG,
GABRP,
GABRQ 💬 		8件: GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬12件: 2, 3, 6, 13, 46, 67, 96, 97, 231, 272, 298, 299 💬
29 Midazolam maleate 💬1件: Midazolam1件: Midazolam16件: GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRB,
GABRB,
GABRB,
GABRD,
GABRE,
GABRG,
GABRG,
GABRG,
GABRP,
GABRQ 💬 		8件: GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬12件: 2, 3, 6, 13, 46, 67, 96, 97, 231, 272, 298, 299 💬
30 Niacinamide 💬1件: Nicotinamide2件: Niacinamide; Nicotinamide--7件: 6, 13, 18, 49, 67, 107, 162 💬
31 Omeprazole 💬1件: Omeprazole3件: Omeprazol; Omeprazole; Omeprazole magnesium2件: ATP4A,
ATP4B 💬 		3件: Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬14件: 6, 13, 21, 46, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298 💬
32 Omeprazole magnesium 💬1件: Omeprazole3件: Omeprazol; Omeprazole; Omeprazole magnesium2件: ATP4A,
ATP4B 💬 		3件: Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬14件: 6, 13, 21, 46, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298 💬
33 Omeprazole sodium 💬1件: Omeprazole3件: Omeprazol; Omeprazole; Omeprazole magnesium2件: ATP4A,
ATP4B 💬 		3件: Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬14件: 6, 13, 21, 46, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298 💬
34 Probucol 💬1件: Probucol1件: Probucol--3件: 21, 66, 79 💬
35 Propofol 💬1件: Propofol1件: Propofol16件: GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRB,
GABRB,
GABRB,
GABRD,
GABRE,
GABRG,
GABRG,
GABRG,
GABRP,
GABRQ 💬 		8件: GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬10件: 3, 6, 21, 22, 34, 46, 70, 97, 98, 296 💬
36 Repaglinide 💬1件: Repaglinide1件: Repaglinide2件: ABCC8,
KCNJ11 💬 		4件: ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬3件: 6, 21, 299 💬
37 Sevoflurane 💬1件: Sevoflurane1件: Sevoflurane--8件: 6, 21, 22, 34, 70, 98, 225, 296 💬
38 Sirolimus 💬1件: Sirolimus2件: Rapamycin; Sirolimus1件: MTOR 💬 49件: AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬44件: 2, 6, 13, 15, 19, 21, 34, 35, 36, 46, 48, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 97, 98, 137, 157, 158, 192, 193, 222, 227, 256, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
39 Sodium dichloroacetate 💬1件: Dichloroacetic acid1件: Dichloroacetate3件: PDK2_3_4,
PDK2_3_4,
PDK2_3_4 💬 		1件: Diabetic cardiomyopathy 💬1件: 21 💬
40 Taurine 💬1件: Taurine1件: Taurine--4件: 13, 21, 201, 337 💬
41 Triglycerides, medium-chain 💬1件: Medium-chain triglycerides2件: Medium chain triglyceride; Medium-chain triglycerides--2件: 21, 318 💬
42 Uridine triacetate 💬1件: Uridine triacetate1件: TRI-O-acetyluridine--1件: 21 💬
43 Vatiquinone 💬1件: Vatiquinone2件: Alpha-tocotrienol quinone; Vatiquinone--3件: 18, 21, 156 💬
44 Zagociguat 💬1件: Zagociguat0件: 3件: GUCY1A,
GUCY1A,
GUCY1B 💬 		10件: Circadian entrainment, Gap junction, Long-term depression, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬-