Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Arginine 1件: Arginine3件: Arginine hydrochloride ,
Arginine ,
Arginine hydrochloride 💬 		--5件: 21, 65, 72, 225, 251 💬
2 Bupropion 2件: Bupropion; Bupropion hydrochloride3件: Bupropion hydrochloride ,
Bupropion ,
Bupropion hydrobromide 💬 		2件: SLC6A2,
SLC6A3 💬 		8件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Neuroactive ligand signaling, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬6件: 8, 18, 21, 96, 97, 171 💬
3 Caffeine 1件: Caffeine3件: Caffeine ,
Caffeine hydrate ,
Caffeine citrate 💬 		11件: ADORA1,
ADORA2A,
PDE1,
PDE2A,
PDE3A,
PDE3B,
PDE4,
PDE4,
PDE4,
PDE4,
PDE5 💬 		22件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬8件: 2, 6, 13, 21, 46, 96, 97, 265 💬
4 Creatine 3件: Acetic acid; Creatine; Creatine monohydrate---14件: 1, 2, 6, 8, 13, 21, 46, 49, 50, 97, 113, 156, 201, 337 💬
5 Cysteamine 6件: 2-aminoethanethiol; Cysteamine; Cysteamine bitartrate; Cysteamine hydrochloride; Mercaptamina; Mercaptamine3件: Cysteamine ,
Cysteamine hydrochloride ,
Cysteamine bitartrate 💬 		--4件: 8, 19, 21, 299 💬
6 Dexmedetomidine 3件: Dexmedetomidina; Dexmedetomidine; Dexmedetomidine hydrochloride2件: Dexmedetomidine ,
Dexmedetomidine hydrochloride 💬 		3件: ADRA2A,
ADRA2B,
ADRA2C 💬 		4件: Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬15件: 2, 4, 6, 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
7 Dextromethorphan 2件: Dextromethorphan; Dextromethorphan hydrobromide3件: Dextromethorphan hydrobromide ,
Dextromethorphan ,
Daunorubicin 💬 		6件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬 		21件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬10件: 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
8 Dichloroacetic acid 1件: Dichloroacetate1件: Sodium dichloroacetate 💬 3件: PDK2_3_4,
PDK2_3_4,
PDK2_3_4 💬 		1件: Diabetic cardiomyopathy 💬2件: 21, 86 💬
9 Elamipretide 1件: Elamipretide2件: Elamipretide ,
Elamipretide hydrochloride 💬 		--3件: 18, 21, 324 💬
10 Flurbiprofen 1件: Flurbiprofen2件: Flurbiprofen ,
Flurbiprofen sodium 💬 		2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬3件: 13, 21, 46 💬
11 Glycerin 1件: Glycerol1件: Glycerin 💬 --10件: 6, 7, 13, 21, 79, 265, 302, 316, 317, 344 💬
12 Idebenone 1件: Idebenone1件: Idebenone 💬 --7件: 6, 8, 13, 18, 21, 113, 302 💬
13 KL1333 1件: KL1333---1件: 21 💬
14 L-arginine 1件: L-arginine---5件: 2, 21, 46, 113, 299 💬
15 L-Glutamine 2件: Glutamine; L-glutamine1件: Glutamine 💬 --11件: 21, 87, 89, 96, 97, 113, 214, 215, 222, 245, 299 💬
16 Lactose 1件: Lactose2件: Anhydrous lactose ,
Lactose 💬 		--7件: 2, 6, 13, 21, 97, 228, 310 💬
17 Medium-chain triglycerides 2件: Medium chain triglyceride; Medium-chain triglycerides1件: Triglycerides, medium-chain 💬 --2件: 21, 318 💬
18 Midazolam 1件: Midazolam3件: Midazolam ,
Midazolam hydrochloride ,
Midazolam maleate 💬 		16件: GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRB,
GABRB,
GABRB,
GABRD,
GABRE,
GABRG,
GABRG,
GABRG,
GABRP,
GABRQ 💬 		8件: GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬13件: 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
19 Nicotinamide 2件: Niacinamide; Nicotinamide1件: Niacinamide 💬 --20件: 2, 5, 6, 7, 8, 13, 17, 18, 21, 46, 49, 60, 63, 65, 67, 85, 97, 107, 162, 191 💬
20 Nicotinamide riboside 2件: Nicotinamide riboside; Nicotinamide riboside chloride---14件: 2, 5, 6, 7, 8, 17, 18, 21, 49, 60, 65, 85, 97, 191 💬
21 Omeprazole 3件: Omeprazol; Omeprazole; Omeprazole magnesium3件: Omeprazole ,
Omeprazole sodium ,
Omeprazole magnesium 💬 		2件: ATP4A,
ATP4B 💬 		3件: Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬16件: 6, 13, 21, 46, 51, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
22 Probucol 1件: Probucol1件: Probucol 💬 --3件: 21, 66, 79 💬
23 Propofol 1件: Propofol1件: Propofol 💬 16件: GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRB,
GABRB,
GABRB,
GABRD,
GABRE,
GABRG,
GABRG,
GABRG,
GABRP,
GABRQ 💬 		8件: GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬10件: 3, 6, 21, 22, 34, 46, 70, 97, 98, 296 💬
24 Repaglinide 1件: Repaglinide1件: Repaglinide 💬 2件: ABCC8,
KCNJ11 💬 		4件: ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬4件: 6, 21, 46, 299 💬
25 Sevoflurane 1件: Sevoflurane1件: Sevoflurane 💬 --8件: 6, 21, 22, 34, 70, 98, 225, 296 💬
26 Sirolimus 2件: Rapamycin; Sirolimus1件: Sirolimus 💬 1件: MTOR 💬 49件: AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬46件: 2, 6, 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 97, 98, 137, 157, 158, 192, 193, 222, 227, 256, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
27 Sonlicromanol 2件: KH176; Sonlicromanol---2件: 21, 302 💬
28 Taurine 1件: Taurine1件: Taurine 💬 --4件: 13, 21, 201, 337 💬
29 Uridine triacetate 1件: TRI-O-acetyluridine1件: Uridine triacetate 💬 --1件: 21 💬
30 Vatiquinone 2件: Alpha-tocotrienol quinone; Vatiquinone1件: Vatiquinone 💬 --3件: 18, 21, 156 💬
31 Zagociguat 0件: 1件: Zagociguat 💬 3件: GUCY1A,
GUCY1A,
GUCY1B 💬 		10件: Circadian entrainment, Gap junction, Long-term depression, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 21 💬