Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank 薬物名（臨床試験情報から抽出） KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acetaminophen 💬1件: Acetaminophen2件: Acetaminophen; Paracetamol2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬17件: 3, 6, 11, 13, 19, 34, 46, 49, 51, 70, 77, 86, 96, 222, 256, 300, 337 💬
2 Albuterol 💬1件: Albuterol2件: Albuterol; Salbutamol1件: ADRB2 💬 11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬13件: 2, 3, 12, 13, 85, 86, 113, 228, 231, 256, 273, 299, 340 💬
3 Albuterol sulfate 💬1件: Albuterol2件: Albuterol; Salbutamol1件: ADRB2 💬 11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬13件: 2, 3, 12, 13, 85, 86, 113, 228, 231, 256, 273, 299, 340 💬
4 Amifampridine 💬1件: Amifampridine2件: Amifampridine; Amifampridine phosphate4件: KCNA4,
KCNC3,
KCND2,
KCND3 💬 		4件: Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬3件: 3, 11, 12 💬
5 Amifampridine phosphate 💬1件: Amifampridine2件: Amifampridine; Amifampridine phosphate4件: KCNA4,
KCNC3,
KCND2,
KCND3 💬 		4件: Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬3件: 3, 11, 12 💬
6 Apitegromab 💬1件: Apitegromab1件: Apitegromab1件: MSTN 💬 1件: Cytokine-cytokine receptor interaction 💬1件: 3 💬
7 Branaplam 💬1件: Branaplam1件: Branaplam--2件: 3, 8 💬
8 Celecoxib 💬1件: Celecoxib1件: Celecoxib1件: PTGS2 💬 22件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬13件: 2, 3, 13, 34, 46, 70, 89, 96, 97, 107, 161, 171, 271 💬
9 Dalfampridine 💬1件: Dalfampridine5件: 4-aminopyridine; 4-AP; Dalfampridine; Fampridina; Fampridine4件: KCNA4,
KCNC3,
KCND2,
KCND3 💬 		4件: Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬4件: 3, 4, 13, 14 💬
10 Divalproex sodium 💬1件: Valproic acid3件: Valproate; Valproate sodium; Valproic acid7件: ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
E4.1.1.15,
E4.1.1.15 💬 		16件: Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬9件: 3, 5, 26, 34, 65, 89, 90, 222, 331 💬
11 Hydroxyurea 💬1件: Hydroxyurea1件: Hydroxyurea1件: RRM2 💬 5件: Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway 💬10件: 3, 13, 19, 20, 46, 65, 85, 86, 107, 284 💬
12 Itraconazole 💬1件: Itraconazole1件: Itraconazole--7件: 2, 3, 65, 96, 97, 227, 299 💬
13 Leuprolide acetate 💬1件: Leuprolide2件: Leuprolide; Leuprorelin1件: GNRHR 💬 3件: GnRH signaling pathway, Hormone signaling, Neuroactive ligand-receptor interaction 💬5件: 1, 2, 3, 67, 76 💬
14 Leuprolide mesylate 💬1件: Leuprolide2件: Leuprolide; Leuprorelin1件: GNRHR 💬 3件: GnRH signaling pathway, Hormone signaling, Neuroactive ligand-receptor interaction 💬5件: 1, 2, 3, 67, 76 💬
15 Leuprorelin 💬1件: Leuprolide2件: Leuprolide; Leuprorelin1件: GNRHR 💬 3件: GnRH signaling pathway, Hormone signaling, Neuroactive ligand-receptor interaction 💬5件: 1, 2, 3, 67, 76 💬
16 Levocarnitine 💬1件: Levocarnitine3件: Carnitine; L-carnitine; Levocarnitine--10件: 3, 13, 46, 53, 58, 86, 96, 97, 240, 265 💬
17 Levocarnitine chloride 💬1件: Levocarnitine3件: Carnitine; L-carnitine; Levocarnitine--10件: 3, 13, 46, 53, 58, 86, 96, 97, 240, 265 💬
18 Midazolam 💬1件: Midazolam1件: Midazolam16件: GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRB,
GABRB,
GABRB,
GABRD,
GABRE,
GABRG,
GABRG,
GABRG,
GABRP,
GABRQ 💬 		8件: GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬12件: 2, 3, 6, 13, 46, 67, 96, 97, 231, 272, 298, 299 💬
19 Midazolam hydrochloride 💬1件: Midazolam1件: Midazolam16件: GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRB,
GABRB,
GABRB,
GABRD,
GABRE,
GABRG,
GABRG,
GABRG,
GABRP,
GABRQ 💬 		8件: GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬12件: 2, 3, 6, 13, 46, 67, 96, 97, 231, 272, 298, 299 💬
20 Midazolam maleate 💬1件: Midazolam1件: Midazolam16件: GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRB,
GABRB,
GABRB,
GABRD,
GABRE,
GABRG,
GABRG,
GABRG,
GABRP,
GABRQ 💬 		8件: GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬12件: 2, 3, 6, 13, 46, 67, 96, 97, 231, 272, 298, 299 💬
21 Nusinersen 💬1件: Nusinersen2件: Nusinersen; Nusinersen sodium--1件: 3 💬
22 Nusinersen sodium 💬1件: Nusinersen2件: Nusinersen; Nusinersen sodium--1件: 3 💬
23 Olesoxime 💬1件: Olesoxime1件: Olesoxime--3件: 2, 3, 13 💬
24 Onasemnogene abeparvovec 💬1件: Onasemnogene abeparvovec1件: Onasemnogene abeparvovec--1件: 3 💬
25 Prednisolone 💬1件: Prednisolone3件: Prednisolona; Prednisolone; Prednisolonum1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬39件: 3, 11, 13, 14, 18, 25, 26, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 54, 56, 60, 63, 64, 66, 81, 84, 85, 96, 97, 113, 145, 162, 222, 251, 269, 271, 296, 299, 300 💬
26 Propofol 💬1件: Propofol1件: Propofol16件: GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRB,
GABRB,
GABRB,
GABRD,
GABRE,
GABRG,
GABRG,
GABRG,
GABRP,
GABRQ 💬 		8件: GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬10件: 3, 6, 21, 22, 34, 46, 70, 97, 98, 296 💬
27 Pyridostigmine bromide 💬1件: Pyridostigmine2件: Pyridostigmine; Pyridostigmine bromide1件: ACHE 💬 3件: Cholinergic synapse, Glycerophospholipid metabolism, Neuroactive ligand signaling 💬5件: 3, 6, 11, 51, 256 💬
28 Reldesemtiv 💬1件: Reldesemtiv2件: CK-2127107; Reldesemtiv3件: TNNC2,
TNNI2,
TNNT3 💬 		3件: Calcium signaling pathway, Cytoskeleton in muscle cells, Motor proteins 💬1件: 2 💬
29 Riluzole 💬1件: Riluzole1件: Riluzole14件: GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		24件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬8件: 2, 3, 5, 8, 13, 17, 203, 206 💬
30 Risdiplam 💬1件: Risdiplam1件: Risdiplam--1件: 3 💬
31 Sesame oil 💬1件: Sesame oil0件: ---
32 Sodium phenylbutyrate 💬1件: Phenylbutyric acid2件: Phenylbutyrate; Sodium phenylbutyrate--9件: 2, 3, 8, 93, 94, 244, 251, 297, 338 💬
33 Somatropin 💬1件: Somatotropin7件: Growth hormone; Human growth hormone; Recombinant human growth hormone; Rhgh; Somatotropin; Somatropin; Somatropina1件: GHR 💬 6件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬26件: 2, 3, 19, 46, 65, 74, 75, 76, 77, 78, 96, 97, 107, 113, 156, 187, 191, 193, 195, 238, 246, 265, 274, 276, 299, 337 💬
34 Sulfuric acid 💬1件: Sulfate ion1件: Sulfate--6件: 2, 3, 11, 49, 222, 224 💬
35 Taldefgrobep alfa 💬1件: Talditercept alfa1件: Taldefgrobep alfa1件: MSTN 💬 1件: Cytokine-cytokine receptor interaction 💬1件: 3 💬
36 Testosterone 💬1件: Testosterone1件: Testosterone1件: AR 💬 4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬6件: 1, 2, 3, 13, 76, 113 💬
37 Valproate sodium 💬1件: Valproic acid3件: Valproate; Valproate sodium; Valproic acid7件: ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
E4.1.1.15,
E4.1.1.15 💬 		16件: Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬9件: 3, 5, 26, 34, 65, 89, 90, 222, 331 💬
38 Valproic acid 💬1件: Valproic acid3件: Valproate; Valproate sodium; Valproic acid7件: ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
E4.1.1.15,
E4.1.1.15 💬 		16件: Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬9件: 3, 5, 26, 34, 65, 89, 90, 222, 331 💬