Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acetaminophen 2件: Acetaminophen; Paracetamol1件: Acetaminophen 💬 2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬18件: 3, 6, 11, 13, 19, 34, 35, 46, 49, 51, 70, 77, 86, 96, 222, 256, 300, 337 💬
2 Albuterol 2件: Albuterol; Salbutamol2件: Albuterol sulfate ,
Albuterol 💬 		1件: ADRB2 💬 11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬16件: 2, 3, 11, 12, 13, 85, 86, 89, 111, 113, 228, 231, 256, 273, 299, 340 💬
3 Amifampridine 2件: Amifampridine; Amifampridine phosphate2件: Amifampridine ,
Amifampridine phosphate 💬 		4件: KCNA4,
KCNC3,
KCND2,
KCND3 💬 		4件: Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬3件: 3, 11, 12 💬
4 Apitegromab 1件: Apitegromab1件: Apitegromab 💬 1件: MSTN 💬 1件: Cytokine-cytokine receptor interaction 💬1件: 3 💬
5 BIIB115 1件: BIIB115---1件: 3 💬
6 Branaplam 1件: Branaplam1件: Branaplam 💬 --2件: 3, 8 💬
7 Celecoxib 1件: Celecoxib1件: Celecoxib 💬 1件: PTGS2 💬 22件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬14件: 2, 3, 6, 13, 34, 46, 70, 89, 96, 97, 107, 161, 171, 271 💬
8 Dalfampridine 5件: 4-aminopyridine; 4-AP; Dalfampridine; Fampridina; Fampridine1件: Dalfampridine 💬 4件: KCNA4,
KCNC3,
KCND2,
KCND3 💬 		4件: Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬4件: 3, 4, 13, 14 💬
9 GYM329 1件: GYM329---2件: 3, 113 💬
10 Hydroxyurea 1件: Hydroxyurea1件: Hydroxyurea 💬 1件: RRM2 💬 5件: Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway 💬10件: 3, 13, 19, 20, 46, 65, 85, 86, 107, 284 💬
11 Itraconazole 1件: Itraconazole1件: Itraconazole 💬 --8件: 2, 3, 46, 65, 96, 97, 227, 299 💬
12 Leuprolide 2件: Leuprolide; Leuprorelin3件: Leuprolide acetate ,
Leuprorelin ,
Leuprolide mesylate 💬 		1件: GNRHR 💬 3件: GnRH signaling pathway, Hormone signaling, Neuroactive ligand-receptor interaction 💬5件: 1, 2, 3, 67, 76 💬
13 Levocarnitine 3件: Carnitine; L-carnitine; Levocarnitine2件: Levocarnitine chloride ,
Levocarnitine 💬 		--11件: 2, 3, 13, 46, 53, 58, 86, 96, 97, 240, 265 💬
14 Midazolam 1件: Midazolam3件: Midazolam ,
Midazolam hydrochloride ,
Midazolam maleate 💬 		16件: GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRB,
GABRB,
GABRB,
GABRD,
GABRE,
GABRG,
GABRG,
GABRG,
GABRP,
GABRQ 💬 		8件: GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬13件: 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
15 Nerve Growth Factor 1件: Nerve growth factor---4件: 2, 3, 53, 90 💬
16 Nusinersen 2件: Nusinersen; Nusinersen sodium2件: Nusinersen sodium ,
Nusinersen 💬 		--1件: 3 💬
17 Olesoxime 1件: Olesoxime1件: Olesoxime 💬 --3件: 2, 3, 13 💬
18 Onasemnogene abeparvovec 1件: Onasemnogene abeparvovec1件: Onasemnogene abeparvovec 💬 --1件: 3 💬
19 Phenylbutyric acid 2件: Phenylbutyrate; Sodium phenylbutyrate1件: Sodium phenylbutyrate 💬 --10件: 2, 3, 8, 15, 93, 94, 244, 251, 297, 338 💬
20 Phosphate ion 1件: Phosphate---13件: 3, 13, 46, 49, 65, 70, 75, 90, 235, 238, 256, 286, 288 💬
21 Prednisolone 3件: Prednisolona; Prednisolone; Prednisolonum1件: Prednisolone 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬41件: 3, 11, 13, 14, 18, 25, 26, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 54, 56, 60, 61, 63, 64, 66, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 251, 269, 271, 296, 299, 300 💬
22 Propofol 1件: Propofol1件: Propofol 💬 16件: GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRB,
GABRB,
GABRB,
GABRD,
GABRE,
GABRG,
GABRG,
GABRG,
GABRP,
GABRQ 💬 		8件: GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬10件: 3, 6, 21, 22, 34, 46, 70, 97, 98, 296 💬
23 Pyridostigmine 2件: Pyridostigmine; Pyridostigmine bromide1件: Pyridostigmine bromide 💬 1件: ACHE 💬 3件: Cholinergic synapse, Glycerophospholipid metabolism, Neuroactive ligand signaling 💬5件: 3, 6, 11, 51, 256 💬
24 Reldesemtiv 2件: CK-2127107; Reldesemtiv1件: Reldesemtiv 💬 3件: TNNC2,
TNNI2,
TNNT3 💬 		3件: Calcium signaling pathway, Cytoskeleton in muscle cells, Motor proteins 💬2件: 2, 3 💬
25 Riluzole 1件: Riluzole1件: Riluzole 💬 14件: GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		24件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬8件: 2, 3, 5, 8, 13, 17, 203, 206 💬
26 Risdiplam 1件: Risdiplam1件: Risdiplam 💬 --1件: 3 💬
27 Sesame oil 0件: 1件: Sesame oil 💬 --1件: 3 💬
28 Somatotropin 7件: Growth hormone; Human growth hormone; Recombinant human growth hormone; Rhgh; Somatotropin; Somatropin; Somatropina1件: Somatropin 💬 1件: GHR 💬 6件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬28件: 2, 3, 13, 19, 36, 46, 65, 74, 75, 76, 77, 78, 96, 97, 107, 113, 156, 187, 191, 193, 195, 238, 246, 265, 274, 276, 299, 337 💬
29 Sulfate ion 1件: Sulfate1件: Sulfuric acid 💬 --8件: 2, 3, 11, 49, 53, 64, 222, 224 💬
30 Talditercept alfa 1件: Taldefgrobep alfa1件: Taldefgrobep alfa 💬 1件: MSTN 💬 1件: Cytokine-cytokine receptor interaction 💬1件: 3 💬
31 Testosterone 1件: Testosterone1件: Testosterone 💬 1件: AR 💬 4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬9件: 1, 2, 3, 13, 60, 76, 78, 113, 265 💬
32 Valproic acid 3件: Valproate; Valproate sodium; Valproic acid3件: Divalproex sodium ,
Valproic acid ,
Valproate sodium 💬 		7件: ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
E4.1.1.15,
E4.1.1.15 💬 		16件: Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬13件: 2, 3, 5, 6, 13, 26, 34, 65, 89, 90, 127, 222, 331 💬