Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank 薬物名（臨床試験情報から抽出） KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acetaminophen 💬1件: Acetaminophen2件: Acetaminophen; Paracetamol2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬17件: 3, 6, 11, 13, 19, 34, 46, 49, 51, 70, 77, 86, 96, 222, 256, 300, 337 💬
2 Cabergoline 💬1件: Cabergoline2件: Cabergolina; Cabergoline2件: DRD2,
PRL 💬 		14件: Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬4件: 6, 74, 75, 77 💬
3 Clomifene 💬1件: Clomifene0件: 2件: ESR1,
ESR2 💬 		10件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Estrogen signaling pathway, GnRH secretion, Hormone signaling, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬-
4 Clomiphene citrate 💬1件: Clomifene0件: 2件: ESR1,
ESR2 💬 		10件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Estrogen signaling pathway, GnRH secretion, Hormone signaling, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬-
5 Denosumab 💬1件: Denosumab1件: Denosumab1件: TNFSF11 💬 8件: Breast cancer, Chemical carcinogenesis - receptor activation, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Parathyroid hormone synthesis, secretion and action, Prolactin signaling pathway, Rheumatoid arthritis 💬10件: 46, 50, 70, 75, 77, 93, 95, 96, 274, 299 💬
6 Dextrose 💬1件: Dextrose, unspecified form2件: Dextrose; Glucose--12件: 6, 13, 56, 60, 66, 77, 96, 97, 201, 226, 254, 299 💬
7 Dopamine 💬1件: Dopamine1件: Dopamine5件: DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬 		13件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬3件: 6, 7, 77 💬
8 Dopamine hydrochloride 💬1件: Dopamine1件: Dopamine5件: DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬 		13件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬3件: 6, 7, 77 💬
9 Empagliflozin 💬1件: Empagliflozin1件: Empagliflozin--10件: 65, 67, 72, 77, 86, 96, 97, 257, 298, 299 💬
10 Escitalopram 💬1件: Escitalopram3件: Citalopram; Escitalopram; Escitalopram oxalate1件: SLC6A4 💬 3件: Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬4件: 2, 6, 13, 46 💬
11 Escitalopram oxalate 💬1件: Escitalopram3件: Citalopram; Escitalopram; Escitalopram oxalate1件: SLC6A4 💬 3件: Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬4件: 2, 6, 13, 46 💬
12 Furosemide 💬1件: Furosemide1件: Furosemide1件: SLC12A2 💬 3件: Pancreatic secretion, Salivary secretion, Vibrio cholerae infection 💬2件: 77, 86 💬
13 Glucose, liquid 💬1件: Dextrose, unspecified form2件: Dextrose; Glucose--12件: 6, 13, 56, 60, 66, 77, 96, 97, 201, 226, 254, 299 💬
14 Lanreotide acetate 💬1件: Lanreotide2件: Lanreotide; Lanreotide acetate2件: SSTR2,
SSTR5 💬 		5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬5件: 67, 73, 77, 85, 298 💬
15 Liraglutide 💬1件: Liraglutide1件: Liraglutide1件: GLP1R 💬 4件: Hormone signaling, Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬5件: 6, 13, 75, 77, 193 💬
16 Metformin 💬1件: Metformin3件: Metformin; Metformin hydrochloride; Metformina2件: PRKAA,
PRKAA 💬 		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬27件: 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 225, 265, 285, 298, 299, 301 💬
17 Metformin hydrochloride 💬1件: Metformin3件: Metformin; Metformin hydrochloride; Metformina2件: PRKAA,
PRKAA 💬 		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬27件: 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 225, 265, 285, 298, 299, 301 💬
18 Octreotide 💬1件: Octreotide3件: Octreotida; Octreotide; Octreotide acetate1件: SSTR2 💬 5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬8件: 67, 75, 77, 84, 85, 89, 193, 227 💬
19 Octreotide acetate 💬1件: Octreotide3件: Octreotida; Octreotide; Octreotide acetate1件: SSTR2 💬 5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬8件: 67, 75, 77, 84, 85, 89, 193, 227 💬
20 Octreotide acetate 💬1件: Octreotide3件: Octreotida; Octreotide; Octreotide acetate1件: SSTR2 💬 5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬8件: 67, 75, 77, 84, 85, 89, 193, 227 💬
21 Octreotide pamoate 💬1件: Octreotide3件: Octreotida; Octreotide; Octreotide acetate1件: SSTR2 💬 5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬8件: 67, 75, 77, 84, 85, 89, 193, 227 💬
22 Paltusotine 💬1件: Paltusotine1件: Paltusotine1件: SSTR2 💬 5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬1件: 77 💬
23 Pasireotide 💬1件: Pasireotide4件: Pasireotida; Pasireotide; Pasireotide diaspartate; Pasireotide pamoate4件: SSTR1,
SSTR2,
SSTR3,
SSTR5 💬 		5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬3件: 74, 75, 77 💬
24 Pasireotide diaspartate 💬1件: Pasireotide4件: Pasireotida; Pasireotide; Pasireotide diaspartate; Pasireotide pamoate4件: SSTR1,
SSTR2,
SSTR3,
SSTR5 💬 		5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬3件: 74, 75, 77 💬
25 Pasireotide pamoate 💬1件: Pasireotide4件: Pasireotida; Pasireotide; Pasireotide diaspartate; Pasireotide pamoate4件: SSTR1,
SSTR2,
SSTR3,
SSTR5 💬 		5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬3件: 74, 75, 77 💬
26 Pegvisomant 💬1件: Pegvisomant1件: Pegvisomant1件: GHR 💬 6件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬2件: 77, 265 💬
27 Phenylalanine 💬1件: Phenylalanine1件: Phenylalanine--1件: 240 💬
28 Raloxifene 💬1件: Raloxifene2件: Raloxifene; Raloxifene hydrochloride2件: ESR1,
ESR2 💬 		10件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Estrogen signaling pathway, GnRH secretion, Hormone signaling, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬2件: 46, 77 💬
29 Raloxifene hydrochloride 💬1件: Raloxifene2件: Raloxifene; Raloxifene hydrochloride2件: ESR1,
ESR2 💬 		10件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Estrogen signaling pathway, GnRH secretion, Hormone signaling, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬2件: 46, 77 💬
30 Rosiglitazone 💬1件: Rosiglitazone2件: Rosiglitazone; Rosiglitazone maleate1件: NR1C3 💬 12件: AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬6件: 46, 75, 77, 97, 222, 265 💬
31 Rosiglitazone maleate 💬1件: Rosiglitazone2件: Rosiglitazone; Rosiglitazone maleate1件: NR1C3 💬 12件: AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬6件: 46, 75, 77, 97, 222, 265 💬
32 Sitagliptin 💬1件: Sitagliptin1件: Sitagliptin1件: DPP4 💬 2件: Protein digestion and absorption, Virion - Hepatitis viruses 💬4件: 6, 75, 77, 299 💬
33 Sitagliptin phosphate 💬1件: Sitagliptin1件: Sitagliptin1件: DPP4 💬 2件: Protein digestion and absorption, Virion - Hepatitis viruses 💬4件: 6, 75, 77, 299 💬
34 Sitagliptin phosphate 💬1件: Sitagliptin1件: Sitagliptin1件: DPP4 💬 2件: Protein digestion and absorption, Virion - Hepatitis viruses 💬4件: 6, 75, 77, 299 💬
35 Somatostatin 💬1件: Somatostatin1件: Somatostatin5件: SSTR1,
SSTR2,
SSTR3,
SSTR4,
SSTR5 💬 		5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬1件: 77 💬
36 Somatropin 💬1件: Somatotropin7件: Growth hormone; Human growth hormone; Recombinant human growth hormone; Rhgh; Somatotropin; Somatropin; Somatropina1件: GHR 💬 6件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬26件: 2, 3, 19, 46, 65, 74, 75, 76, 77, 78, 96, 97, 107, 113, 156, 187, 191, 193, 195, 238, 246, 265, 274, 276, 299, 337 💬
37 Tadalafil 💬1件: Tadalafil2件: Tadalafil; Tadalafilo1件: PDE5 💬 2件: Purine metabolism, cGMP-PKG signaling pathway 💬7件: 6, 51, 75, 77, 84, 86, 113 💬
38 Tryptophan 💬1件: Tryptophan2件: Propanoic acid; Tryptophan--2件: 6, 46 💬
39 Tyrosine 💬1件: Tyrosine3件: Alanine; Propanoic acid; Tyrosine--3件: 6, 86, 298 💬
40 Zoledronate disodium 💬1件: Zoledronic acid3件: Zoledronate; Zoledronic acid; Zoledronic acid monohydrate1件: FDPS 💬 3件: Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬14件: 6, 13, 46, 65, 75, 77, 93, 95, 96, 97, 270, 274, 299, 333 💬
41 Zoledronate trisodium 💬1件: Zoledronic acid3件: Zoledronate; Zoledronic acid; Zoledronic acid monohydrate1件: FDPS 💬 3件: Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬14件: 6, 13, 46, 65, 75, 77, 93, 95, 96, 97, 270, 274, 299, 333 💬
42 Zoledronic acid 💬1件: Zoledronic acid3件: Zoledronate; Zoledronic acid; Zoledronic acid monohydrate1件: FDPS 💬 3件: Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬14件: 6, 13, 46, 65, 75, 77, 93, 95, 96, 97, 270, 274, 299, 333 💬
43 Zoledronic acid 💬1件: Zoledronic acid3件: Zoledronate; Zoledronic acid; Zoledronic acid monohydrate1件: FDPS 💬 3件: Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬14件: 6, 13, 46, 65, 75, 77, 93, 95, 96, 97, 270, 274, 299, 333 💬
44 Zoledronic acid hemipentahydrate 💬1件: Zoledronic acid3件: Zoledronate; Zoledronic acid; Zoledronic acid monohydrate1件: FDPS 💬 3件: Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬14件: 6, 13, 46, 65, 75, 77, 93, 95, 96, 97, 270, 274, 299, 333 💬