Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank 薬物名（臨床試験情報から抽出） KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acetaminophen 💬1件: Acetaminophen2件: Acetaminophen; PARACETAMOL2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬19件: 11, 13, 19, 34, 35, 46, 49, 51, 63, 70, 77, 86, 96, 222, 231, 256, 271, 300, 337 💬
2 Cabergoline 💬1件: Cabergoline2件: CABERGOLINA; CABERGOLINE2件: DRD2,
PRL 💬 		14件: Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬4件: 6, 74, 75, 77 💬
3 Denosumab 💬1件: Denosumab1件: Denosumab1件: TNFSF11 💬 8件: Breast cancer, Chemical carcinogenesis - receptor activation, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Parathyroid hormone synthesis, secretion and action, Prolactin signaling pathway, Rheumatoid arthritis 💬11件: 46, 50, 70, 75, 77, 93, 95, 96, 223, 274, 299 💬
4 Dopamine 💬1件: Dopamine1件: Dopamine5件: DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬 		13件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬5件: 6, 7, 17, 74, 77 💬
5 Dopamine hydrochloride 💬1件: Dopamine1件: Dopamine5件: DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬 		13件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬5件: 6, 7, 17, 74, 77 💬
6 Empagliflozin 💬1件: Empagliflozin1件: Empagliflozin--17件: 28, 46, 57, 58, 65, 67, 72, 77, 86, 96, 97, 113, 222, 223, 257, 298, 299 💬
7 Escitalopram 💬1件: Escitalopram3件: Citalopram; ESCITALOPRAM; Escitalopram oxalate1件: SLC6A4 💬 3件: Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬5件: 2, 6, 13, 46, 77 💬
8 Escitalopram oxalate 💬1件: Escitalopram3件: Citalopram; Escitalopram; Escitalopram oxalate1件: SLC6A4 💬 3件: Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬5件: 2, 6, 13, 46, 77 💬
9 Furosemide 💬1件: Furosemide1件: Furosemide1件: SLC12A2 💬 3件: Pancreatic secretion, Salivary secretion, Vibrio cholerae infection 💬5件: 6, 57, 77, 86, 222 💬
10 Lanreotide acetate 💬1件: Lanreotide3件: LANREOTIDA; LANREOTIDE; LANREOTIDE ACETATE2件: SSTR2,
SSTR5 💬 		5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬5件: 67, 73, 77, 85, 298 💬
11 Liraglutide 💬1件: Liraglutide1件: Liraglutide1件: GLP1R 💬 4件: Hormone signaling, Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬5件: 6, 13, 75, 77, 193 💬
12 Metformin 💬1件: Metformin4件: Metformin; Metformin hydrochloride; METFORMINA; Metformine2件: PRKAA1,
PRKAA2 💬 		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬31件: 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬
13 Metformin hydrochloride 💬1件: Metformin4件: Metformin; Metformin hydrochloride; Metformina; Metformine2件: PRKAA1,
PRKAA2 💬 		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬31件: 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬
14 Octreotide 💬1件: Octreotide4件: OCTREOTIDA; Octreotide; OCTREOTIDE ACETATE; OCTREOTIDE HYDROCHLORIDE1件: SSTR2 💬 5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬8件: 67, 75, 77, 84, 85, 89, 193, 227 💬
15 Octreotide acetate 💬1件: Octreotide4件: OCTREOTIDA; Octreotide; OCTREOTIDE ACETATE; OCTREOTIDE HYDROCHLORIDE1件: SSTR2 💬 5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬8件: 67, 75, 77, 84, 85, 89, 193, 227 💬
16 Octreotide acetate 💬1件: Octreotide4件: OCTREOTIDA; Octreotide; OCTREOTIDE ACETATE; OCTREOTIDE HYDROCHLORIDE1件: SSTR2 💬 5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬8件: 67, 75, 77, 84, 85, 89, 193, 227 💬
17 Octreotide hydrochloride 💬1件: Octreotide4件: OCTREOTIDA; OCTREOTIDE; OCTREOTIDE ACETATE; OCTREOTIDE HYDROCHLORIDE1件: SSTR2 💬 5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬8件: 67, 75, 77, 84, 85, 89, 193, 227 💬
18 Octreotide pamoate 💬1件: Octreotide4件: OCTREOTIDA; Octreotide; OCTREOTIDE ACETATE; OCTREOTIDE HYDROCHLORIDE1件: SSTR2 💬 5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬8件: 67, 75, 77, 84, 85, 89, 193, 227 💬
19 Paltusotine 💬1件: Paltusotine1件: Paltusotine1件: SSTR2 💬 5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬1件: 77 💬
20 Paltusotine hydrochloride 💬1件: Paltusotine1件: Paltusotine1件: SSTR2 💬 5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬1件: 77 💬
21 Pasireotide 💬1件: Pasireotide4件: Pasireotida; Pasireotide; PASIREOTIDE DIASPARTATE; PASIREOTIDE PAMOATE4件: SSTR1,
SSTR2,
SSTR3,
SSTR5 💬 		5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬4件: 67, 74, 75, 77 💬
22 Pasireotide diaspartate 💬1件: Pasireotide4件: Pasireotida; PASIREOTIDE; PASIREOTIDE DIASPARTATE; PASIREOTIDE PAMOATE4件: SSTR1,
SSTR2,
SSTR3,
SSTR5 💬 		5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬4件: 67, 74, 75, 77 💬
23 Pasireotide pamoate 💬1件: Pasireotide4件: Pasireotida; PASIREOTIDE; PASIREOTIDE DIASPARTATE; PASIREOTIDE PAMOATE4件: SSTR1,
SSTR2,
SSTR3,
SSTR5 💬 		5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬4件: 67, 74, 75, 77 💬
24 Pegvisomant 💬1件: Pegvisomant1件: PEGVISOMANT1件: GHR 💬 6件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬2件: 77, 265 💬
25 Raloxifene 💬1件: Raloxifene2件: Raloxifene; Raloxifene hydrochloride2件: ESR1,
ESR2 💬 		10件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Estrogen signaling pathway, GnRH secretion, Hormone signaling, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬2件: 46, 77 💬
26 Raloxifene hydrochloride 💬1件: Raloxifene2件: Raloxifene; Raloxifene hydrochloride2件: ESR1,
ESR2 💬 		10件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Estrogen signaling pathway, GnRH secretion, Hormone signaling, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬2件: 46, 77 💬
27 Rosiglitazone 💬1件: Rosiglitazone2件: Rosiglitazone; Rosiglitazone maleate1件: PPARG 💬 12件: AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬7件: 46, 57, 75, 77, 97, 222, 265 💬
28 Rosiglitazone maleate 💬1件: Rosiglitazone2件: Rosiglitazone; Rosiglitazone maleate1件: PPARG 💬 12件: AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬7件: 46, 57, 75, 77, 97, 222, 265 💬
29 Sitagliptin 💬1件: Sitagliptin1件: Sitagliptin1件: DPP4 💬 2件: Protein digestion and absorption, Virion - Hepatitis viruses 💬6件: 6, 63, 75, 77, 233, 299 💬
30 Sitagliptin phosphate 💬1件: Sitagliptin1件: Sitagliptin1件: DPP4 💬 2件: Protein digestion and absorption, Virion - Hepatitis viruses 💬6件: 6, 63, 75, 77, 233, 299 💬
31 Sitagliptin phosphate 💬1件: Sitagliptin1件: Sitagliptin1件: DPP4 💬 2件: Protein digestion and absorption, Virion - Hepatitis viruses 💬6件: 6, 63, 75, 77, 233, 299 💬
32 Somatostatin 💬1件: Somatostatin1件: Somatostatin5件: SSTR1,
SSTR2,
SSTR3,
SSTR4,
SSTR5 💬 		5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬2件: 67, 77 💬
33 Tadalafil 💬1件: Tadalafil2件: Tadalafil; TADALAFILO1件: PDE5A 💬 2件: Purine metabolism, cGMP-PKG signaling pathway 💬8件: 6, 51, 75, 77, 84, 86, 113, 210 💬
34 Tryptophan 💬1件: Tryptophan2件: Propanoic acid; Tryptophan--3件: 6, 46, 77 💬
35 Zoledronate disodium 💬1件: Zoledronic acid2件: Zoledronic Acid; ZOLEDRONIC ACID MONOHYDRATE1件: FDPS 💬 3件: Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬16件: 5, 6, 13, 17, 46, 75, 77, 93, 95, 96, 97, 270, 274, 282, 299, 333 💬
36 Zoledronate trisodium 💬1件: Zoledronic acid2件: Zoledronic Acid; ZOLEDRONIC ACID MONOHYDRATE1件: FDPS 💬 3件: Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬16件: 5, 6, 13, 17, 46, 75, 77, 93, 95, 96, 97, 270, 274, 282, 299, 333 💬
37 Zoledronic acid 💬1件: Zoledronic acid2件: Zoledronic acid; ZOLEDRONIC ACID MONOHYDRATE1件: FDPS 💬 3件: Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬16件: 5, 6, 13, 17, 46, 75, 77, 93, 95, 96, 97, 270, 274, 282, 299, 333 💬
38 Zoledronic acid 💬1件: Zoledronic acid2件: ZOLEDRONIC ACID; ZOLEDRONIC ACID MONOHYDRATE1件: FDPS 💬 3件: Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬16件: 5, 6, 13, 17, 46, 75, 77, 93, 95, 96, 97, 270, 274, 282, 299, 333 💬
39 Zoledronic acid hemipentahydrate 💬1件: Zoledronic acid2件: Zoledronic acid; ZOLEDRONIC ACID MONOHYDRATE1件: FDPS 💬 3件: Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬16件: 5, 6, 13, 17, 46, 75, 77, 93, 95, 96, 97, 270, 274, 282, 299, 333 💬