Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acetaminophen 2件: Acetaminophen; PARACETAMOL1件: Acetaminophen 💬 2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬19件: 11, 13, 19, 34, 35, 46, 49, 51, 63, 70, 77, 86, 96, 222, 231, 256, 271, 300, 337 💬
2 Acetate 1件: Acetate---52件: 1, 2, 6, 10, 11, 13, 22, 35, 40, 46, 49, 51, 60, 63, 64, 65, 66, 67, 70, 71, 73, 75, 76, 77, 78, 79, 81, 83, 85, 86, 88, 89, 90, 96, 97, 113, 145, 156, 158, 162, 171, 206, 222, 223, 224, 225, 227, 235, 251, 265, 298, 299 💬
3 Cabergoline 2件: CABERGOLINA; CABERGOLINE1件: Cabergoline 💬 2件: DRD2,
PRL 💬 		14件: Alcoholism, Cocaine addiction, Cytokine-cytokine receptor interaction, Dopaminergic synapse, Gap junction, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Parkinson disease, Prolactin signaling pathway, Rap1 signaling pathway, cAMP signaling pathway 💬4件: 6, 74, 75, 77 💬
4 D-Tryptophan 2件: D-Tryptophan; Tryptophan---1件: 77 💬
5 Denosumab 1件: Denosumab1件: Denosumab 💬 1件: TNFSF11 💬 8件: Breast cancer, Chemical carcinogenesis - receptor activation, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Parathyroid hormone synthesis, secretion and action, Prolactin signaling pathway, Rheumatoid arthritis 💬11件: 46, 50, 70, 75, 77, 93, 95, 96, 223, 274, 299 💬
6 Dopamine 1件: Dopamine2件: Dopamine hydrochloride ,
Dopamine 💬 		5件: DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬 		13件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬5件: 6, 7, 17, 74, 77 💬
7 Dopastatin 1件: Dopastatin---1件: 77 💬
8 Empagliflozin 1件: Empagliflozin1件: Empagliflozin 💬 --17件: 28, 46, 57, 58, 65, 67, 72, 77, 86, 96, 97, 113, 222, 223, 257, 298, 299 💬
9 Escitalopram 3件: Citalopram; Escitalopram; Escitalopram oxalate2件: Escitalopram oxalate ,
Escitalopram 💬 		1件: SLC6A4 💬 3件: Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬5件: 2, 6, 13, 46, 77 💬
10 Furosemide 1件: Furosemide1件: Furosemide 💬 1件: SLC12A2 💬 3件: Pancreatic secretion, Salivary secretion, Vibrio cholerae infection 💬5件: 6, 57, 77, 86, 222 💬
11 Gadolinium 1件: Gadolinium---8件: 13, 34, 46, 65, 77, 86, 113, 305 💬
12 Gold 1件: Gold---71件: 2, 5, 6, 11, 13, 17, 19, 21, 22, 28, 34, 35, 46, 49, 50, 53, 54, 56, 57, 58, 60, 63, 64, 65, 66, 68, 71, 75, 76, 77, 79, 84, 85, 86, 88, 91, 93, 95, 96, 97, 98, 107, 113, 127, 137, 158, 162, 167, 171, 193, 206, 215, 218, 222, 223, 224, 226, 227, 228, 230, 235, 271, 291, 294, 296, 298, 299, 310, 318, 331, 340 💬
13 Lanreotide 3件: LANREOTIDA; Lanreotide; LANREOTIDE ACETATE1件: Lanreotide acetate 💬 2件: SSTR2,
SSTR5 💬 		5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬5件: 67, 73, 77, 85, 298 💬
14 Liraglutide 1件: LIRAGLUTIDE1件: Liraglutide 💬 1件: GLP1R 💬 4件: Hormone signaling, Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬5件: 6, 13, 75, 77, 193 💬
15 Metformin 4件: Metformin; METFORMIN HYDROCHLORIDE; Metformina; Metformine2件: Metformin hydrochloride ,
Metformin 💬 		2件: PRKAA1,
PRKAA2 💬 		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬31件: 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬
16 Octreotide 4件: OCTREOTIDA; Octreotide; OCTREOTIDE ACETATE; OCTREOTIDE HYDROCHLORIDE5件: Octreotide ,
Octreotide acetate ,
Octreotide pamoate ,
Octreotide acetate ,
Octreotide hydrochloride 💬 		1件: SSTR2 💬 5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬8件: 67, 75, 77, 84, 85, 89, 193, 227 💬
17 Paltusotine 1件: Paltusotine2件: Paltusotine ,
Paltusotine hydrochloride 💬 		1件: SSTR2 💬 5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬1件: 77 💬
18 Pasireotide 4件: Pasireotida; Pasireotide; PASIREOTIDE DIASPARTATE; PASIREOTIDE PAMOATE3件: Pasireotide ,
Pasireotide diaspartate ,
Pasireotide pamoate 💬 		4件: SSTR1,
SSTR2,
SSTR3,
SSTR5 💬 		5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬4件: 67, 74, 75, 77 💬
19 Pegvisomant 1件: PEGVISOMANT1件: Pegvisomant 💬 1件: GHR 💬 6件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, Hormone signaling, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬2件: 77, 265 💬
20 Raloxifene 2件: Raloxifene; Raloxifene hydrochloride2件: Raloxifene hydrochloride ,
Raloxifene 💬 		2件: ESR1,
ESR2 💬 		10件: Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Estrogen signaling pathway, GnRH secretion, Hormone signaling, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬2件: 46, 77 💬
21 Rosiglitazone 2件: Rosiglitazone; Rosiglitazone maleate2件: Rosiglitazone maleate ,
Rosiglitazone 💬 		1件: PPARG 💬 12件: AMPK signaling pathway, Efferocytosis, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬7件: 46, 57, 75, 77, 97, 222, 265 💬
22 Sitagliptin 1件: Sitagliptin3件: Sitagliptin phosphate ,
Sitagliptin ,
Sitagliptin phosphate 💬 		1件: DPP4 💬 2件: Protein digestion and absorption, Virion - Hepatitis viruses 💬6件: 6, 63, 75, 77, 233, 299 💬
23 Somatostatin 1件: Somatostatin1件: Somatostatin 💬 5件: SSTR1,
SSTR2,
SSTR3,
SSTR4,
SSTR5 💬 		5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬2件: 67, 77 💬
24 Tadalafil 2件: Tadalafil; TADALAFILO1件: Tadalafil 💬 1件: PDE5A 💬 2件: Purine metabolism, cGMP-PKG signaling pathway 💬8件: 6, 51, 75, 77, 84, 86, 113, 210 💬
25 Tryptophan 2件: Propanoic acid; Tryptophan1件: Tryptophan 💬 --3件: 6, 46, 77 💬
26 Zoledronic acid 2件: Zoledronic acid; ZOLEDRONIC ACID MONOHYDRATE5件: Zoledronic acid ,
Zoledronate disodium ,
Zoledronate trisodium ,
Zoledronic acid ,
Zoledronic acid hemipentahydrate 💬 		1件: FDPS 💬 3件: Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬16件: 5, 6, 13, 17, 46, 75, 77, 93, 95, 96, 97, 270, 274, 282, 299, 333 💬