Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 LCK 💬 11件: NF-kappa B signaling pathway, Osteoclast differentiation, IgSF CAM signaling, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Yersinia infection, Human T-cell leukemia virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency Dasatinib 💬 Dasatinib 3件: 13, 51, 85 💬
2 LCK 💬 11件: NF-kappa B signaling pathway, Osteoclast differentiation, IgSF CAM signaling, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Yersinia infection, Human T-cell leukemia virus 1 infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency Dasatinib 💬 Dasatinib 3件: 13, 51, 85 💬
3 LDHA 💬 7件: Glycolysis / Gluconeogenesis, Cysteine and methionine metabolism, Pyruvate metabolism, Propanoate metabolism, HIF-1 signaling pathway, Glucagon signaling pathway, Central carbon metabolism in cancer Nedosiran sodium 💬 Nedosiran 1件: 234 💬
4 LEPR 💬 7件: Cytokine-cytokine receptor interaction, Neuroactive ligand-receptor interaction, Hormone signaling, AMPK signaling pathway, JAK-STAT signaling pathway, Adipocytokine signaling pathway, Non-alcoholic fatty liver disease Metreleptin 💬 Metreleptin 1件: 265 💬
5 LILRA4 💬 2件: Osteoclast differentiation, B cell receptor signaling pathway Daxdilimab 💬 Daxdilimab 2件: 49, 50 💬
6 LIPA 💬 4件: Steroid biosynthesis, Lysosome biogenesis, Efferocytosis, Cholesterol metabolism Sebelipase alfa 💬 Sebelipase alfa 1件: 19 💬
7 LIPC 💬 2件: Glycerolipid metabolism, Cholesterol metabolism Dextran sulfate sodium 💬 Dextran 5件: 2, 62, 79, 96, 97 💬
8 LPAR1 💬 8件: Rap1 signaling pathway, Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Gap junction, Regulation of actin cytoskeleton, Pathogenic Escherichia coli infection, Pathways in cancer Admilparant 💬 BMS-986278 1件: 85 💬
9 LPL 💬 4件: Glycerolipid metabolism, PPAR signaling pathway, Cholesterol metabolism, Alzheimer disease Dextran sulfate sodium 💬 Dextran 5件: 2, 62, 79, 96, 97 💬
10 LTA 💬 7件: Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, NF-kappa B signaling pathway, TNF signaling pathway, Type I diabetes mellitus, Human T-cell leukemia virus 1 infection, Herpes simplex virus 1 infection Etanercept 💬 Etanercept 16件: 15, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
11 LTB 💬 3件: Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Rheumatoid arthritis Baminercept 💬 Baminercept 4件: 13, 46, 53, 97 💬