Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 NAGLU 💬 2件: Glycosaminoglycan degradation, Lysosome biogenesis Tralesinidase alfa 💬 Tralesinidase alfa 1件: 19 💬
2 NCBP1 💬 4件: Nucleocytoplasmic transport, mRNA surveillance pathway, Spliceosome, Amyotrophic lateral sclerosis Obefazimod 💬 Obefazimod 2件: 96, 97 💬
3 NCBP2 💬 3件: Nucleocytoplasmic transport, mRNA surveillance pathway, Spliceosome Obefazimod 💬 Obefazimod 2件: 96, 97 💬
4 NCBP2L 💬 3件: Nucleocytoplasmic transport, mRNA surveillance pathway, Spliceosome Obefazimod 💬 Obefazimod 2件: 96, 97 💬
5 NCSTN 💬 3件: Notch signaling pathway, Cadherin signaling, Alzheimer disease Tarenflurbil 💬 Tarenflurbil 1件: 13 💬
6 NFE2L2 💬 7件: Protein processing in endoplasmic reticulum, Parkinson disease, Pathways in cancer, Chemical carcinogenesis - reactive oxygen species, Hepatocellular carcinoma, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Omaveloxolone 💬 Omaveloxolone 1件: 18 💬
7 NFKB1 💬 76件: MAPK signaling pathway, Ras signaling pathway, cAMP signaling pathway, Chemokine signaling pathway, NF-kappa B signaling pathway, HIF-1 signaling pathway, Sphingolipid signaling pathway, PI3K-Akt signaling pathway, Apoptosis, Longevity regulating pathway, Cellular senescence, Osteoclast differentiation, Cadherin signaling, Neutrophil extracellular trap formation, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Cytosolic DNA-sensing pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, TNF signaling pathway, Neurotrophin signaling pathway, Prolactin signaling pathway, Adipocytokine signaling pathway, Relaxin signaling pathway, Insulin resistance, Non-alcoholic fatty liver disease, AGE-RAGE signaling pathway in diabetic complications, Alcoholic liver disease, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Cocaine addiction, Epithelial cell signaling in Helicobacter pylori infection, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Legionellosis, Yersinia infection, Leishmaniasis, Chagas disease, Toxoplasmosis, Amoebiasis, Tuberculosis, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, Coronavirus disease, Pathways in cancer, Transcriptional misregulation in cancer, Viral carcinogenesis, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Pancreatic cancer, Prostate cancer, Chronic myeloid leukemia, Acute myeloid leukemia, Small cell lung cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, Inflammatory bowel disease, Diabetic cardiomyopathy, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Iguratimod 💬 Iguratimod 7件: 46, 49, 51, 53, 63, 271, 300 💬
8 NGF 💬 9件: MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, Apoptosis, Neurotrophin signaling pathway, Inflammatory mediator regulation of TRP channels Tanezumab 💬 Tanezumab 2件: 226, 298 💬
9 NGFR 💬 9件: Virion - Ebolavirus, Lyssavirus and Morbillivirus, MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, Apoptosis - multiple species, Neurotrophin signaling pathway, Transcriptional misregulation in cancer Cenegermin 💬 Cenegermin 1件: 53 💬
10 NLRP3 💬 12件: Necroptosis, NOD-like receptor signaling pathway, Cytosolic DNA-sensing pathway, C-type lectin receptor signaling pathway, Pathogenic Escherichia coli infection, Shigellosis, Salmonella infection, Pertussis, Yersinia infection, Influenza A, Coronavirus disease, Lipid and atherosclerosis Usnoflast 💬 Usnoflast 1件: 2 💬
11 NPC1L1 💬 1件: Fat digestion and absorption Ezetimibe 💬 Ezetimibe 5件: 49, 79, 93, 149, 260 💬
12 NPR1 💬 10件: Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Hormone signaling, Vascular smooth muscle contraction, Thermogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Aldosterone synthesis and secretion Nesiritide 💬 Nesiritide 1件: 57 💬
13 NPR2 💬 5件: Purine metabolism, cGMP-PKG signaling pathway, Hormone signaling, Vascular smooth muscle contraction, Oxytocin signaling pathway Navepegritide 💬 Navepegritide 1件: 276 💬
14 NPR2 💬 5件: Purine metabolism, cGMP-PKG signaling pathway, Hormone signaling, Vascular smooth muscle contraction, Oxytocin signaling pathway Vosoritide 💬 Vosoritide 3件: 19, 195, 276 💬
15 NQO1 💬 5件: Ubiquinone and other terpenoid-quinone biosynthesis, Pathways in cancer, Chemical carcinogenesis - reactive oxygen species, Hepatocellular carcinoma, Fluid shear stress and atherosclerosis Warfarin 💬 Warfarin 15件: 6, 8, 13, 19, 46, 48, 49, 66, 85, 86, 88, 91, 96, 97, 222 💬
16 NQO1 💬 5件: Ubiquinone and other terpenoid-quinone biosynthesis, Pathways in cancer, Chemical carcinogenesis - reactive oxygen species, Hepatocellular carcinoma, Fluid shear stress and atherosclerosis Warfarin potassium 💬 Warfarin 15件: 6, 8, 13, 19, 46, 48, 49, 66, 85, 86, 88, 91, 96, 97, 222 💬
17 NQO1 💬 5件: Ubiquinone and other terpenoid-quinone biosynthesis, Pathways in cancer, Chemical carcinogenesis - reactive oxygen species, Hepatocellular carcinoma, Fluid shear stress and atherosclerosis Warfarin sodium 💬 Warfarin 15件: 6, 8, 13, 19, 46, 48, 49, 66, 85, 86, 88, 91, 96, 97, 222 💬
18 NR1H4 💬 1件: Bile secretion Norucholic acid 💬 norUrsodeoxycholic acid 1件: 94 💬
19 NR1H4 💬 1件: Bile secretion Ursodiol 💬 Ursodeoxycholic acid 10件: 6, 46, 67, 84, 93, 94, 95, 96, 97, 296 💬
20 NR1H4 💬 1件: Bile secretion Chenodiol 💬 Chenodeoxycholic acid 5件: 20, 86, 96, 234, 263 💬
21 NR1H4 💬 1件: Bile secretion Obeticholic acid 💬 Obeticholic acid 3件: 93, 265, 296 💬
22 NR1H4 💬 1件: Bile secretion Tropifexor 💬 Tropifexor 1件: 93 💬
23 NR1H4 💬 1件: Bile secretion Cholic acid 💬 Cholic Acid 4件: 20, 234, 265, 310 💬
24 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Deflazacort 💬 Deflazacort 2件: 30, 113 💬
25 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Fluticasone 💬 Fluticasone 4件: 98, 228, 299, 306 💬
26 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Prednisone 💬 Prednisone 58件: 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 127, 145, 162, 164, 205, 222, 223, 224, 228, 251, 269, 283, 284, 285, 288, 299, 300, 303, 307, 331 💬
27 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Clobetasol propionate 💬 Clobetasol propionate 3件: 35, 46, 162 💬
28 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Halometasone 💬 Halometasone 1件: 162 💬
29 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Hydrocortisone acetate 💬 Hydrocortisone acetate 1件: 97 💬
30 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Budesonide 💬 Budesonide 10件: 66, 93, 94, 95, 96, 97, 98, 223, 228, 299 💬
31 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Hydrocortisone sodium succinate 💬 Hydrocortisone succinate 3件: 81, 83, 97 💬
32 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Betamethasone acetate 💬 Betamethasone 9件: 2, 28, 46, 56, 65, 83, 90, 96, 235 💬
33 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Beclometasone 💬 Beclomethasone dipropionate 2件: 97, 98 💬
34 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Betamethasone 💬 Betamethasone 9件: 2, 28, 46, 56, 65, 83, 90, 96, 235 💬
35 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Hydrocortisone 💬 Hydrocortisone 10件: 6, 41, 46, 53, 75, 78, 81, 83, 97, 299 💬
36 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Triamcinolone acetonide 💬 Triamcinolone 11件: 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬
37 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Fluocinolone acetonide 💬 Fluocinolone acetonide 1件: 90 💬
38 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Prednisolone sodium succinate 💬 Prednisolone hemisuccinate 1件: 95 💬
39 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Triamcinolone 💬 Triamcinolone 11件: 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬
40 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Cortisone 💬 Cortisone 1件: 81 💬
41 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Prednisolone 💬 Prednisolone 48件: 3, 11, 13, 14, 18, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 54, 56, 57, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 111, 113, 145, 162, 222, 223, 251, 269, 271, 296, 299, 300 💬
42 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Triamcinolone diacetate 💬 Triamcinolone 11件: 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬
43 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Hydrocortisone succinate 💬 Hydrocortisone succinate 3件: 81, 83, 97 💬
44 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Prednisolone acetate 💬 Prednisolone acetate 2件: 222, 223 💬
45 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Relacorilant 💬 Relacorilant 1件: 75 💬
46 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Betamethasone sodium phosphate 💬 Betamethasone 9件: 2, 28, 46, 56, 65, 83, 90, 96, 235 💬
47 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Betamethasone benzoate 💬 Betamethasone 9件: 2, 28, 46, 56, 65, 83, 90, 96, 235 💬
48 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Hydrocortisone sodium phosphate 💬 Hydrocortisone phosphate 3件: 53, 81, 83 💬
49 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Dazucorilant 💬 Dazucorilant 1件: 2 💬
50 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Methylprednisolone sodium succinate 💬 Methylprednisolone hemisuccinate 8件: 13, 46, 49, 50, 51, 85, 211, 222 💬
51 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Beclomethasone dipropionate 💬 Beclomethasone dipropionate 2件: 97, 98 💬
52 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Clobetasol 💬 Clobetasol 5件: 35, 39, 46, 51, 162 💬
53 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Prednisolone hemisuccinate 💬 Prednisolone hemisuccinate 1件: 95 💬
54 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Dexamethasone phosphate 💬 Dexamethasone 29件: 13, 14, 16, 19, 28, 35, 46, 53, 63, 64, 65, 70, 71, 74, 75, 81, 84, 90, 96, 97, 162, 222, 223, 235, 257, 283, 296, 299, 331 💬
55 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Betamethasone valerate 💬 Betamethasone 9件: 2, 28, 46, 56, 65, 83, 90, 96, 235 💬
56 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Dexamethasone 21-acetate 💬 Dexamethasone acetate 1件: 63 💬
57 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Dexamethasone palmitate 💬 Dexamethasone palmitate 1件: 63 💬
58 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Triamcinolone hexacetonide 💬 Triamcinolone 11件: 35, 46, 53, 56, 70, 90, 96, 107, 162, 226, 298 💬
59 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Vamorolone 💬 Vamorolone 2件: 97, 113 💬
60 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Cortisone acetate 💬 Cortisone acetate 1件: 81 💬
61 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Methylprednisolone 💬 Methylprednisolone 51件: 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 111, 127, 145, 162, 164, 211, 222, 223, 224, 271, 283, 284, 285, 296, 300 💬
62 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Mometasone furoate hydrate 💬 Mometasone furoate 2件: 98, 162 💬
63 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Mometasone 💬 Mometasone 2件: 98, 162 💬
64 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Methylprednisolone acetate 💬 Methylprednisolone 51件: 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 111, 127, 145, 162, 164, 211, 222, 223, 224, 271, 283, 284, 285, 296, 300 💬
65 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Methylprednisolone hemisuccinate 💬 Methylprednisolone hemisuccinate 8件: 13, 46, 49, 50, 51, 85, 211, 222 💬
66 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Beclomethasone dipropionate monohydrate 💬 Beclomethasone dipropionate 2件: 97, 98 💬
67 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Ciclesonide 💬 Ciclesonide 1件: 84 💬
68 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Dexamethasone 💬 Dexamethasone 29件: 13, 14, 16, 19, 28, 35, 46, 53, 63, 64, 65, 70, 71, 74, 75, 81, 84, 90, 96, 97, 162, 222, 223, 235, 257, 283, 296, 299, 331 💬
69 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Mifepristone 💬 Mifepristone 1件: 75 💬
70 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Fluticasone propionate 💬 Fluticasone propionate 3件: 98, 228, 306 💬
71 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Prednisolone sodium phosphate 💬 Prednisolone phosphate 3件: 3, 13, 97 💬
72 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Betamethasone dipropionate 💬 Betamethasone 9件: 2, 28, 46, 56, 65, 83, 90, 96, 235 💬
73 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Dexamethasone sodium phosphate 💬 Dexamethasone 29件: 13, 14, 16, 19, 28, 35, 46, 53, 63, 64, 65, 70, 71, 74, 75, 81, 84, 90, 96, 97, 162, 222, 223, 235, 257, 283, 296, 299, 331 💬
74 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Prednisone acetate 💬 Prednisone acetate 9件: 35, 40, 46, 49, 63, 66, 162, 222, 224 💬
75 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Mometasone furoate 💬 Mometasone furoate 2件: 98, 162 💬
76 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Dexamethasone acetate 💬 Dexamethasone acetate 1件: 63 💬
77 NR3C2 💬 1件: Aldosterone-regulated sodium reabsorption Eplerenone 💬 Eplerenone 5件: 57, 75, 113, 210, 215 💬
78 NR3C2 💬 1件: Aldosterone-regulated sodium reabsorption Spironolactone 💬 Spironolactone 12件: 46, 57, 58, 67, 86, 113, 210, 214, 218, 222, 223, 225 💬
79 NR3C2 💬 1件: Aldosterone-regulated sodium reabsorption Fludrocortisone 💬 Fludrocortisone 3件: 6, 17, 81 💬
80 NR3C2 💬 1件: Aldosterone-regulated sodium reabsorption Drospirenone 💬 Drospirenone 1件: 118 💬
81 NR3C2 💬 1件: Aldosterone-regulated sodium reabsorption Aldosterone 💬 Aldosterone 3件: 57, 75, 222 💬
82 NR3C2 💬 1件: Aldosterone-regulated sodium reabsorption Fludrocortisone acetate 💬 Fludrocortisone 3件: 6, 17, 81 💬
83 NR3C2 💬 1件: Aldosterone-regulated sodium reabsorption Finerenone 💬 Finerenone 5件: 66, 218, 222, 223, 224 💬