Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 AKR1B 💬 5件: Pentose and glucuronate interconversions, Fructose and mannose metabolism, Galactose metabolism, Glycerolipid metabolism, Folate biosynthesis Epalrestat 💬 Epalrestat 1件: 10 💬
2 DHFR 💬 3件: One carbon pool by folate, Folate biosynthesis, Folate transport and metabolism Methotrexate sodium 💬 Methotrexate 39件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 56, 60, 62, 65, 84, 85, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 284, 285, 286, 326, 331 💬
3 DHFR 💬 3件: One carbon pool by folate, Folate biosynthesis, Folate transport and metabolism Methotrexate 💬 Methotrexate 39件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 56, 60, 62, 65, 84, 85, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 284, 285, 286, 326, 331 💬
4 DHFR 💬 3件: One carbon pool by folate, Folate biosynthesis, Folate transport and metabolism Methotrexate sodium 💬 Methotrexate 39件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 56, 60, 62, 65, 84, 85, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 284, 285, 286, 326, 331 💬
5 DHFR 💬 3件: One carbon pool by folate, Folate biosynthesis, Folate transport and metabolism Methotrexate 💬 Methotrexate 39件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 56, 60, 62, 65, 84, 85, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 284, 285, 286, 326, 331 💬
6 E3.1.3.1 💬 2件: Thiamine metabolism, Folate biosynthesis Ilofotase alfa 💬 Recombinant human alkaline phosphatase 1件: 172 💬
7 E3.1.3.1 💬 2件: Thiamine metabolism, Folate biosynthesis Asfotase alfa 💬 Asfotase alfa 1件: 172 💬
8 phhA 💬 3件: Phenylalanine metabolism, Phenylalanine, tyrosine and tryptophan biosynthesis, Folate biosynthesis Pegvaliase 💬 Pegvaliase 1件: 240 💬
9 TPH1_2 💬 3件: Tryptophan metabolism, Folate biosynthesis, Serotonergic synapse Rodatristat 💬 Rodatristat 1件: 86 💬
10 TPH1_2 💬 3件: Tryptophan metabolism, Folate biosynthesis, Serotonergic synapse Rodatristat ethyl 💬 Rodatristat ethyl 1件: 86 💬
11 TPH1_2 💬 3件: Tryptophan metabolism, Folate biosynthesis, Serotonergic synapse Telotristat 💬 Telotristat 1件: 97 💬
12 TPH1_2 💬 3件: Tryptophan metabolism, Folate biosynthesis, Serotonergic synapse Telotristat 💬 Telotristat 1件: 97 💬