Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Alcoholism 💬
1件: DRD2 💬 Chlorpromazine 💬 Chlorpromazine 1件: 254 💬
2 Alcoholism 💬
1件: DRD2 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine 1件: 254 💬
3 Alzheimer disease 💬
3件: CHRM1, CHRM3, CHRM5 💬 Chlorpromazine 💬 Chlorpromazine 1件: 254 💬
4 Alzheimer disease 💬
3件: CHRM1, CHRM3, CHRM5 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine 1件: 254 💬
5 Calcium signaling pathway 💬
8件: CHRM1, CHRM2, CHRM3, CHRM5, HRH1, HTR2, HTR2, HTR2 💬 Chlorpromazine 💬 Chlorpromazine 1件: 254 💬
6 Calcium signaling pathway 💬
8件: CHRM1, CHRM2, CHRM3, CHRM5, HRH1, HTR2, HTR2, HTR2 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine 1件: 254 💬
7 Calcium signaling pathway 💬
1件: HRH2 💬 Cimetidine 💬 Cimetidine 2件:  2 , 254 💬
8 Calcium signaling pathway 💬
1件: HRH2 💬 Cimetidine hydrochloride 💬 Cimetidine 2件:  2 , 254 💬
9 cAMP signaling pathway 💬
3件: CHRM1, CHRM2, DRD2 💬 Chlorpromazine 💬 Chlorpromazine 1件: 254 💬
10 cAMP signaling pathway 💬
3件: CHRM1, CHRM2, DRD2 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine 1件: 254 💬
11 cGMP-PKG signaling pathway 💬
3件: ADRA2A, ADRA2B, ADRA2C 💬 Chlorpromazine 💬 Chlorpromazine 1件: 254 💬
12 cGMP-PKG signaling pathway 💬
3件: ADRA2A, ADRA2B, ADRA2C 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine 1件: 254 💬
13 Chemical carcinogenesis - reactive oxygen species 💬
1件: HMOX1 💬 Stannsoporfin 💬 Stannsoporfin 1件: 254 💬
14 Cholinergic synapse 💬
5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Chlorpromazine 💬 Chlorpromazine 1件: 254 💬
15 Cholinergic synapse 💬
5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine 1件: 254 💬
16 Cocaine addiction 💬
1件: DRD2 💬 Chlorpromazine 💬 Chlorpromazine 1件: 254 💬
17 Cocaine addiction 💬
1件: DRD2 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine 1件: 254 💬
18 Dopaminergic synapse 💬
1件: DRD2 💬 Chlorpromazine 💬 Chlorpromazine 1件: 254 💬
19 Dopaminergic synapse 💬
1件: DRD2 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine 1件: 254 💬
20 Ferroptosis 💬
1件: HMOX1 💬 Stannsoporfin 💬 Stannsoporfin 1件: 254 💬
21 Fluid shear stress and atherosclerosis 💬
1件: HMOX1 💬 Stannsoporfin 💬 Stannsoporfin 1件: 254 💬
22 Gap junction 💬
4件: DRD2, HTR2, HTR2, HTR2 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine 1件: 254 💬
23 Gap junction 💬
4件: DRD2, HTR2, HTR2, HTR2 💬 Chlorpromazine 💬 Chlorpromazine 1件: 254 💬
24 Gastric acid secretion 💬
1件: CHRM3 💬 Chlorpromazine 💬 Chlorpromazine 1件: 254 💬
25 Gastric acid secretion 💬
1件: CHRM3 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine 1件: 254 💬
26 Gastric acid secretion 💬
1件: HRH2 💬 Cimetidine 💬 Cimetidine 2件:  2 , 254 💬
27 Gastric acid secretion 💬
1件: HRH2 💬 Cimetidine hydrochloride 💬 Cimetidine 2件:  2 , 254 💬
28 Glycine, serine and threonine metabolism 💬
1件: E2.3.1.37 💬 Givosiran 💬 Givosiran 1件: 254 💬
29 Glycine, serine and threonine metabolism 💬
1件: E2.3.1.37 💬 Givosiran sodium 💬 Givosiran 1件: 254 💬
30 Glycine, serine and threonine metabolism 💬
2件: E2.3.1.37, E2.3.1.37 💬 Hemin 💬 Hemin 1件: 254 💬
31 Hepatocellular carcinoma 💬
1件: HMOX1 💬 Stannsoporfin 💬 Stannsoporfin 1件: 254 💬
32 HIF-1 signaling pathway 💬
1件: HMOX1 💬 Stannsoporfin 💬 Stannsoporfin 1件: 254 💬
33 Hormone signaling 💬
4件: ADRA2A, ADRA2B, ADRA2C, DRD2 💬 Chlorpromazine 💬 Chlorpromazine 1件: 254 💬
34 Hormone signaling 💬
4件: ADRA2A, ADRA2B, ADRA2C, DRD2 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine 1件: 254 💬
35 Hormone signaling 💬
1件: MC1R 💬 Afamelanotide 💬 Afamelanotide 2件: 159, 254 💬
36 Hormone signaling 💬
1件: MC1R 💬 Afamelanotide acetate 💬 Afamelanotide 2件: 159, 254 💬
37 Hormone signaling 💬
1件: MC1R 💬 Dersimelagon 💬 Dersimelagon 2件: 51, 254 💬
38 Inflammatory mediator regulation of TRP channels 💬
4件: HRH1, HTR2, HTR2, HTR2 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine 1件: 254 💬
39 Inflammatory mediator regulation of TRP channels 💬
4件: HRH1, HTR2, HTR2, HTR2 💬 Chlorpromazine 💬 Chlorpromazine 1件: 254 💬
40 Insulin secretion 💬
1件: CHRM3 💬 Chlorpromazine 💬 Chlorpromazine 1件: 254 💬
41 Insulin secretion 💬
1件: CHRM3 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine 1件: 254 💬
42 Melanogenesis 💬
1件: MC1R 💬 Afamelanotide 💬 Afamelanotide 2件: 159, 254 💬
43 Melanogenesis 💬
1件: MC1R 💬 Afamelanotide acetate 💬 Afamelanotide 2件: 159, 254 💬
44 Melanogenesis 💬
1件: MC1R 💬 Dersimelagon 💬 Dersimelagon 2件: 51, 254 💬
45 MicroRNAs in cancer 💬
1件: HMOX1 💬 Stannsoporfin 💬 Stannsoporfin 1件: 254 💬
46 Mineral absorption 💬
2件: HMOX1, HMOX2 💬 Stannsoporfin 💬 Stannsoporfin 1件: 254 💬
47 Neuroactive ligand signaling 💬
13件: ADRA2A, ADRA2B, ADRA2C, CHRM1, CHRM2, CHRM3, CHRM4, CHRM5, DRD2, HRH1, HTR2, HTR2, HTR2 💬 Chlorpromazine 💬 Chlorpromazine 1件: 254 💬
48 Neuroactive ligand signaling 💬
13件: ADRA2A, ADRA2B, ADRA2C, CHRM1, CHRM2, CHRM3, CHRM4, CHRM5, DRD2, HRH1, HTR2, HTR2, HTR2 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine 1件: 254 💬
49 Neuroactive ligand signaling 💬
1件: HRH2 💬 Cimetidine 💬 Cimetidine 2件:  2 , 254 💬
50 Neuroactive ligand signaling 💬
1件: HRH2 💬 Cimetidine hydrochloride 💬 Cimetidine 2件:  2 , 254 💬
51 Neuroactive ligand-receptor interaction 💬
13件: ADRA2A, ADRA2B, ADRA2C, CHRM1, CHRM2, CHRM3, CHRM4, CHRM5, DRD2, HRH1, HTR2, HTR2, HTR2 💬 Chlorpromazine 💬 Chlorpromazine 1件: 254 💬
52 Neuroactive ligand-receptor interaction 💬
13件: ADRA2A, ADRA2B, ADRA2C, CHRM1, CHRM2, CHRM3, CHRM4, CHRM5, DRD2, HRH1, HTR2, HTR2, HTR2 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine 1件: 254 💬
53 Neuroactive ligand-receptor interaction 💬
1件: HRH2 💬 Cimetidine 💬 Cimetidine 2件:  2 , 254 💬
54 Neuroactive ligand-receptor interaction 💬
1件: HRH2 💬 Cimetidine hydrochloride 💬 Cimetidine 2件:  2 , 254 💬
55 Neuroactive ligand-receptor interaction 💬
1件: MC1R 💬 Afamelanotide 💬 Afamelanotide 2件: 159, 254 💬
56 Neuroactive ligand-receptor interaction 💬
1件: MC1R 💬 Afamelanotide acetate 💬 Afamelanotide 2件: 159, 254 💬
57 Neuroactive ligand-receptor interaction 💬
1件: MC1R 💬 Dersimelagon 💬 Dersimelagon 2件: 51, 254 💬
58 Pancreatic secretion 💬
1件: CHRM3 💬 Chlorpromazine 💬 Chlorpromazine 1件: 254 💬
59 Pancreatic secretion 💬
1件: CHRM3 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine 1件: 254 💬
60 Parkinson disease 💬
1件: DRD2 💬 Chlorpromazine 💬 Chlorpromazine 1件: 254 💬
61 Parkinson disease 💬
1件: DRD2 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine 1件: 254 💬
62 Pathways in cancer 💬
1件: HMOX1 💬 Stannsoporfin 💬 Stannsoporfin 1件: 254 💬
63 Pathways of neurodegeneration - multiple diseases 💬
3件: CHRM1, CHRM3, CHRM5 💬 Chlorpromazine 💬 Chlorpromazine 1件: 254 💬
64 Pathways of neurodegeneration - multiple diseases 💬
3件: CHRM1, CHRM3, CHRM5 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine 1件: 254 💬
65 PI3K-Akt signaling pathway 💬
2件: CHRM1, CHRM2 💬 Chlorpromazine 💬 Chlorpromazine 1件: 254 💬
66 PI3K-Akt signaling pathway 💬
2件: CHRM1, CHRM2 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine 1件: 254 💬
67 Porphyrin metabolism 💬
1件: E2.3.1.37 💬 Givosiran 💬 Givosiran 1件: 254 💬
68 Porphyrin metabolism 💬
1件: E2.3.1.37 💬 Givosiran sodium 💬 Givosiran 1件: 254 💬
69 Porphyrin metabolism 💬
2件: E2.3.1.37, E2.3.1.37 💬 Hemin 💬 Hemin 1件: 254 💬
70 Porphyrin metabolism 💬
2件: HMOX1, HMOX2 💬 Stannsoporfin 💬 Stannsoporfin 1件: 254 💬
71 Rap1 signaling pathway 💬
1件: DRD2 💬 Chlorpromazine 💬 Chlorpromazine 1件: 254 💬
72 Rap1 signaling pathway 💬
1件: DRD2 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine 1件: 254 💬
73 Regulation of actin cytoskeleton 💬
5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Chlorpromazine 💬 Chlorpromazine 1件: 254 💬
74 Regulation of actin cytoskeleton 💬
5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine 1件: 254 💬
75 Salivary secretion 💬
1件: CHRM3 💬 Chlorpromazine 💬 Chlorpromazine 1件: 254 💬
76 Salivary secretion 💬
1件: CHRM3 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine 1件: 254 💬
77 Serotonergic synapse 💬
3件: HTR2, HTR2, HTR2 💬 Chlorpromazine 💬 Chlorpromazine 1件: 254 💬
78 Serotonergic synapse 💬
3件: HTR2, HTR2, HTR2 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine 1件: 254 💬
79 Taste transduction 💬
1件: CHRM3 💬 Chlorpromazine 💬 Chlorpromazine 1件: 254 💬
80 Taste transduction 💬
1件: CHRM3 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine 1件: 254 💬