Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 ADRA2A 💬 4件: cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Chlorpromazine hydrochloride 💬 Chlorpromazine 2件: 120, 254 💬
2 ADRA2A 💬 4件: cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Chlorpromazine 💬 Chlorpromazine 2件: 120, 254 💬
3 ADRA2B 💬 4件: cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Chlorpromazine 💬 Chlorpromazine 2件: 120, 254 💬
4 ADRA2B 💬 4件: cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Chlorpromazine hydrochloride 💬 Chlorpromazine 2件: 120, 254 💬
5 ADRA2C 💬 4件: cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Chlorpromazine hydrochloride 💬 Chlorpromazine 2件: 120, 254 💬
6 ADRA2C 💬 4件: cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling Chlorpromazine 💬 Chlorpromazine 2件: 120, 254 💬
7 ALAS1 💬 2件: Glycine, serine and threonine metabolism, Porphyrin metabolism Givosiran sodium 💬 Givosiran 1件: 254 💬
8 ALAS1 💬 2件: Glycine, serine and threonine metabolism, Porphyrin metabolism Hemin 💬 Hemin 1件: 254 💬
9 ALAS1 💬 2件: Glycine, serine and threonine metabolism, Porphyrin metabolism Givosiran 💬 Givosiran 1件: 254 💬
10 ALAS2 💬 2件: Glycine, serine and threonine metabolism, Porphyrin metabolism Hemin 💬 Hemin 1件: 254 💬
11 CHRM1 💬 9件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Chlorpromazine 💬 Chlorpromazine 2件: 120, 254 💬
12 CHRM1 💬 9件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Chlorpromazine hydrochloride 💬 Chlorpromazine 2件: 120, 254 💬
13 CHRM2 💬 7件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton Chlorpromazine hydrochloride 💬 Chlorpromazine 2件: 120, 254 💬
14 CHRM2 💬 7件: Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton Chlorpromazine 💬 Chlorpromazine 2件: 120, 254 💬
15 CHRM3 💬 12件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Chlorpromazine 💬 Chlorpromazine 2件: 120, 254 💬
16 CHRM3 💬 12件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Taste transduction, Regulation of actin cytoskeleton, Insulin secretion, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Chlorpromazine hydrochloride 💬 Chlorpromazine 2件: 120, 254 💬
17 CHRM4 💬 4件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Regulation of actin cytoskeleton Chlorpromazine hydrochloride 💬 Chlorpromazine 2件: 120, 254 💬
18 CHRM4 💬 4件: Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Regulation of actin cytoskeleton Chlorpromazine 💬 Chlorpromazine 2件: 120, 254 💬
19 CHRM5 💬 7件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Regulation of actin cytoskeleton, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Chlorpromazine hydrochloride 💬 Chlorpromazine 2件: 120, 254 💬
20 CHRM5 💬 7件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Cholinergic synapse, Regulation of actin cytoskeleton, Alzheimer disease, Pathways of neurodegeneration - multiple diseases Chlorpromazine 💬 Chlorpromazine 2件: 120, 254 💬
21 DRD2 💬 10件: Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Chlorpromazine hydrochloride 💬 Chlorpromazine 2件: 120, 254 💬
22 DRD2 💬 10件: Rap1 signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Neuroactive ligand signaling, Gap junction, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Alcoholism Chlorpromazine 💬 Chlorpromazine 2件: 120, 254 💬
23 HRH1 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Chlorpromazine 💬 Chlorpromazine 2件: 120, 254 💬
24 HRH1 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Chlorpromazine hydrochloride 💬 Chlorpromazine 2件: 120, 254 💬
25 HRH2 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gastric acid secretion Cimetidine hydrochloride 💬 Cimetidine 2件: 2, 254 💬
26 HRH2 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gastric acid secretion Cimetidine 💬 Cimetidine 2件: 2, 254 💬
27 HTR2A 💬 6件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Chlorpromazine hydrochloride 💬 Chlorpromazine 2件: 120, 254 💬
28 HTR2A 💬 6件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Chlorpromazine 💬 Chlorpromazine 2件: 120, 254 💬
29 HTR2B 💬 6件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Chlorpromazine 💬 Chlorpromazine 2件: 120, 254 💬
30 HTR2B 💬 6件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Chlorpromazine hydrochloride 💬 Chlorpromazine 2件: 120, 254 💬
31 HTR2C 💬 6件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Chlorpromazine hydrochloride 💬 Chlorpromazine 2件: 120, 254 💬
32 HTR2C 💬 6件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels Chlorpromazine 💬 Chlorpromazine 2件: 120, 254 💬
33 MC1R 💬 3件: Neuroactive ligand-receptor interaction, Hormone signaling, Melanogenesis Afamelanotide acetate 💬 Afamelanotide 2件: 159, 254 💬
34 MC1R 💬 3件: Neuroactive ligand-receptor interaction, Hormone signaling, Melanogenesis Dersimelagon 💬 Dersimelagon 2件: 51, 254 💬
35 MC1R 💬 3件: Neuroactive ligand-receptor interaction, Hormone signaling, Melanogenesis Afamelanotide 💬 Afamelanotide 2件: 159, 254 💬
36 SLC6A9 💬 2件: Neuroactive ligand signaling, Synaptic vesicle cycle Bitopertin 💬 Bitopertin 2件: 254, 284 💬