Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
12-isopropyl-3H-naphtho[2,1-d]imidazole-4,5-dione[1] Imidazole---[1] 21 💬
22-{[(8Z)-13-[(methylcarbamoyl)formamido]- tridec-8-en-1-yl]oxy}acetic acid[1] Acetic acid[1] Acetic acid, glacial 💬 --[1] 21 💬
32-{[(8Z)-13-[(methylcarbamoyl)formamido]-tridec-8-en-1-yl]oxy}acetic acid[1] Acetic acid[1] Acetic acid, glacial 💬 --[1] 21 💬
4[A042917017]----[1] 21 💬
5[MTP-131]----[1] 21 💬
6[OMT-28]----[1] 21 💬
7[PTC743]----[2] 18, 21 💬
8ABI-009----[1] 21 💬
9Acetic acid[1] Acetic acid[1] Acetic acid, glacial 💬 --[3] 21, 97, 296 💬
10Acetylcysteine[1] Acetylcysteine[1] Acetylcysteine 💬 --[25] 2, 6, 13, 19, 20, 21, 34, 49, 51, 53, 58, 63, 85, 90, 94, 97, 111, 164, 193, 233, 296, 298, 299, 303, 337 💬
11Alfa-tocotrienolo chinone----[1] 21 💬
12Alpha-tocotrienol quinone[2] Tocotrienol,
Vatiquinone		[1] Vatiquinone 💬 --[3] 18, 21, 156 💬
13Arginine[1] Arginine[3] Arginine hydrochloride ,
Arginine ,
Arginine hydrochloride 💬 		--[16] 2, 21, 46, 57, 58, 67, 72, 96, 97, 98, 113, 210, 223, 225, 251, 299 💬
14Arginine and citrulline supplementations[2] Arginine,
Citrulline		[5] Arginine hydrochloride ,
Arginine ,
Arginine hydrochloride ,
L-Citrulline ,
Citrulline malate 💬 		--[1] 21 💬
15Blood Collection----[5] 21, 65, 201, 229, 271 💬
16Bupropion[1] Bupropion[3] Bupropion hydrochloride ,
Bupropion ,
Bupropion hydrobromide 💬 		[2] SLC6A2,
SLC6A3 💬 		[8] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Neuroactive ligand signaling, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[7] 8, 18, 21, 96, 97, 171, 298 💬
17Caffeine[1] Caffeine[2] Caffeine ,
Caffeine citrate 💬 		[11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬 		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 2, 6, 13, 21, 46, 96, 97, 265 💬
18CD34+ cells enriched with MNV-BLD----[1] 21 💬
19Citrulline[1] Citrulline[2] L-Citrulline ,
Citrulline malate 💬 		--[3] 21, 86, 113 💬
20CoenzymeQ10----[1] 21 💬
21Creatine[1] Creatine---[18] 1, 2, 3, 5, 6, 8, 13, 15, 21, 46, 49, 50, 97, 113, 156, 201, 256, 337 💬
22Cysteamine[1] Cysteamine[3] Cysteamine ,
Cysteamine hydrochloride ,
Cysteamine bitartrate 💬 		--[4] 8, 19, 21, 299 💬
23Cysteamine Bitartrate[1] Cysteamine[3] Cysteamine ,
Cysteamine hydrochloride ,
Cysteamine bitartrate 💬 		--[4] 8, 19, 21, 299 💬
24D-Mannitol[1] Mannitol[1] Mannitol 💬 --[1] 21 💬
25DEXMEDETOMIDINE[1] Dexmedetomidine[2] Dexmedetomidine ,
Dexmedetomidine hydrochloride 💬 		[3] ADRA2A,
ADRA2B,
ADRA2C 💬 		[4] Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[15] 2, 4, 6, 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
26Dextromethorphan[1] Dextromethorphan[3] Dextromethorphan hydrobromide ,
Dextromethorphan ,
Dextromethorphan polistirex 💬 		[6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬 		[21] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
27Diagnostic Test: blood drawing----[1] 21 💬
28Diagnostic Test: Cardiopulmonary Exercise Testing----[1] 21 💬
29Diagnostic Test: Creatine Chemical Exchange Saturation Transfer (CrCEST) Imaging Sequence[1] Creatine---[1] 21 💬
30Dichloroacetate----[1] 21 💬
31Elamipretide[1] Elamipretide[2] Elamipretide ,
Elamipretide hydrochloride 💬 		--[3] 18, 21, 324 💬
32Elamipretide (high dose)[1] Elamipretide[2] Elamipretide ,
Elamipretide hydrochloride 💬 		--[1] 21 💬
33Elamipretide (intermediate dose)[1] Elamipretide[2] Elamipretide ,
Elamipretide hydrochloride 💬 		--[1] 21 💬
34Elamipretide (low dose)[1] Elamipretide[2] Elamipretide ,
Elamipretide hydrochloride 💬 		--[1] 21 💬
35EPI-743----[3] 21, 156, 337 💬
36EPI-743 15 mg/kg----[1] 21 💬
37EPI-743 5 mg/kg----[1] 21 💬
38EPI743----[1] 21 💬
39Exercise Pedal----[1] 21 💬
40Feburane----[1] 21 💬
41FLURBIPROFEN[1] Flurbiprofen[2] Flurbiprofen ,
Flurbiprofen sodium 💬 		[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[3] 13, 21, 46 💬
42Fluzone®----[1] 21 💬
43Gentle Jogger----[1] 21 💬
44Glutamine oral supplement----[1] 21 💬
45Glutamine oral supplementation----[1] 21 💬
46Glycerol Tributyrate----[2] 21, 302 💬
47Gold[1] Gold---[71] 2, 5, 6, 11, 13, 17, 19, 21, 22, 28, 34, 35, 46, 49, 50, 53, 54, 56, 57, 58, 60, 63, 64, 65, 66, 68, 71, 75, 76, 77, 79, 84, 85, 86, 88, 91, 93, 95, 96, 97, 98, 107, 113, 127, 137, 158, 162, 167, 171, 193, 206, 215, 218, 222, 223, 224, 226, 227, 228, 230, 235, 271, 291, 294, 296, 298, 299, 310, 318, 331, 340 💬
48Idebenone[1] Idebenone[1] Idebenone 💬 --[9] 6, 8, 13, 17, 18, 21, 113, 115, 302 💬
49Imidazole[1] Imidazole---[1] 21 💬
50IW-6463 Tablets----[1] 21 💬
51Ketogenic Diet----[7] 13, 21, 49, 77, 127, 145, 148 💬
52KH176[1] Sonlicromanol---[2] 21, 302 💬
53KL1333[1] KL1333---[1] 21 💬
54KL1333 100 mg[1] KL1333---[1] 21 💬
55KL1333 200 mg[1] KL1333---[1] 21 💬
56KL1333 25 mg[1] KL1333---[1] 21 💬
57KL1333 400 mg[1] KL1333---[1] 21 💬
58KL1333 50 mg[1] KL1333---[1] 21 💬
59KL1333 600 mg[1] KL1333---[1] 21 💬
60KL1333 800 mg[1] KL1333---[1] 21 💬
61L-arginine[2] Arginine,
L-arginine		[3] Arginine hydrochloride ,
Arginine ,
Arginine hydrochloride 💬 		--[10] 2, 21, 46, 67, 96, 97, 98, 113, 223, 299 💬
62L-Citrulline[1] Citrulline[2] L-Citrulline ,
Citrulline malate 💬 		--[1] 21 💬
63Lactose[1] Lactose[2] Anhydrous lactose ,
Lactose hydrate 💬 		--[8] 2, 6, 13, 21, 97, 107, 228, 310 💬
64Low Residue Diet Intervention----[1] 21 💬
65Lumason® contrast agent----[1] 21 💬
66Mannitol[1] Mannitol[1] Mannitol 💬 --[8] 6, 13, 21, 28, 60, 96, 113, 299 💬
67Medium-Chain Triglycerides[1] Medium-chain triglycerides[1] Triglycerides, medium-chain 💬 --[2] 21, 344 💬
68Midazolam[1] Midazolam[3] Midazolam ,
Midazolam hydrochloride ,
Midazolam maleate 💬 		[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
69Midazolam injection[1] Midazolam[3] Midazolam ,
Midazolam hydrochloride ,
Midazolam maleate 💬 		[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[1] 21 💬
70MNV-201----[1] 21 💬
71MTP-131----[1] 21 💬
72N-Acetylcysteine[1] Acetylcysteine[1] Acetylcysteine 💬 --[14] 6, 13, 19, 20, 21, 49, 58, 85, 90, 111, 164, 296, 299, 337 💬
73Napazimone----[1] 21 💬
74Nicotinamide[1] Nicotinamide[1] Niacinamide 💬 --[19] 2, 5, 6, 7, 8, 17, 18, 21, 46, 49, 60, 63, 65, 85, 97, 107, 162, 191, 302 💬
75Nicotinamide riboside[2] Nicotinamide,
Nicotinamide riboside		[1] Niacinamide 💬 --[14] 2, 5, 6, 7, 8, 17, 18, 21, 49, 60, 65, 85, 97, 191 💬
76Nicotinamide treatment[1] Nicotinamide[1] Niacinamide 💬 --[2] 21, 302 💬
77Off-label compassionate drug use----[1] 21 💬
78Omeprazole[1] Omeprazole[3] Omeprazole ,
Omeprazole sodium ,
Omeprazole magnesium 💬 		[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[18] 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
79OMT-28----[1] 21 💬
80Oral administration of 100 mg KH176 twice daily----[1] 21 💬
81Other: generation of iPSCs----[1] 21 💬
82PGz Bed----[1] 21 💬
83Pheburane----[1] 21 💬
84Probucol[1] Probucol[1] Probucol 💬 --[4] 21, 66, 79, 223 💬
85Propofol[1] Propofol[1] Propofol 💬 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[10] 3, 6, 21, 22, 34, 46, 70, 97, 98, 296 💬
86PTC743----[2] 18, 21 💬
87Reagila----[1] 21 💬
88Repaglinide[1] Repaglinide[1] Repaglinide 💬 [2] ABCC8,
KCNJ11 💬 		[4] ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬[4] 6, 21, 46, 299 💬
89RG2133 (2',3',5'-tri-O-acetyluridine)----[1] 21 💬
90Sevoflurane[1] Sevoflurane[1] Sevoflurane 💬 --[8] 6, 21, 22, 34, 70, 98, 225, 296 💬
91Sirolimus[1] Sirolimus[1] Sirolimus 💬 [1] MTOR 💬 [52] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, Integrated stress response (ISR) signaling pathway, Integrin signaling, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, Lysosome biogenesis, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[46] 6, 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 54, 57, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 97, 98, 111, 127, 137, 157, 158, 192, 222, 223, 227, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
92Skin biopsy----[6] 6, 19, 21, 51, 84, 86 💬
93SODIUM PYRUVATE[1] Pyruvic acid---[6] 2, 21, 67, 85, 299, 318 💬
94Sonlicromanol[1] Sonlicromanol---[1] 21 💬
95Taurine[1] Taurine[1] Taurine 💬 --[4] 13, 21, 201, 337 💬
96Tocotrienol[1] Tocotrienol---[4] 18, 21, 156, 299 💬
97TTI-0102----[1] 21 💬
98TTI-0102: cysteamine-pantetheine disulfide[1] Cysteamine[3] Cysteamine ,
Cysteamine hydrochloride ,
Cysteamine bitartrate 💬 		--[1] 21 💬
99VATIQUINONE[1] Vatiquinone[1] Vatiquinone 💬 --[2] 18, 21 💬
100Zagociguat[1] Zagociguat[1] Zagociguat 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬 		[10] Circadian entrainment, Gap junction, Long-term depression, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 21 💬
101Zagociguat 15mg[1] Zagociguat[1] Zagociguat 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬 		[10] Circadian entrainment, Gap junction, Long-term depression, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 21 💬
102Zagociguat 30mg[1] Zagociguat[1] Zagociguat 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬 		[10] Circadian entrainment, Gap junction, Long-term depression, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 21 💬