Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Arginine [1] Arginine[3] Arginine hydrochloride ,
Arginine ,
Arginine hydrochloride 💬 		--[5] 21, 65, 72, 225, 251 💬
2 Bupropion [2] Bupropion; Bupropion hydrochloride[3] Bupropion hydrochloride ,
Bupropion ,
Bupropion hydrobromide 💬 		[2] SLC6A2,
SLC6A3 💬 		[8] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Neuroactive ligand signaling, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[6] 8, 18, 21, 96, 97, 171 💬
3 Caffeine [1] Caffeine[3] Caffeine ,
Caffeine hydrate ,
Caffeine citrate 💬 		[11] ADORA1,
ADORA2A,
PDE1,
PDE2A,
PDE3A,
PDE3B,
PDE4,
PDE4,
PDE4,
PDE4,
PDE5 💬 		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 2, 6, 13, 21, 46, 96, 97, 265 💬
4 Creatine [3] Acetic acid; Creatine; Creatine monohydrate---[14] 1, 2, 6, 8, 13, 21, 46, 49, 50, 97, 113, 156, 201, 337 💬
5 Cysteamine [6] 2-aminoethanethiol; Cysteamine; Cysteamine bitartrate; Cysteamine hydrochloride; Mercaptamina; Mercaptamine[3] Cysteamine ,
Cysteamine hydrochloride ,
Cysteamine bitartrate 💬 		--[4] 8, 19, 21, 299 💬
6 Dexmedetomidine [3] Dexmedetomidina; Dexmedetomidine; Dexmedetomidine hydrochloride[2] Dexmedetomidine ,
Dexmedetomidine hydrochloride 💬 		[3] ADRA2A,
ADRA2B,
ADRA2C 💬 		[4] Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[15] 2, 4, 6, 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
7 Dextromethorphan [2] Dextromethorphan; Dextromethorphan hydrobromide[3] Dextromethorphan hydrobromide ,
Dextromethorphan ,
Daunorubicin 💬 		[6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬 		[21] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
8 Dichloroacetic acid [1] Dichloroacetate[1] Sodium dichloroacetate 💬 [3] PDK2_3_4,
PDK2_3_4,
PDK2_3_4 💬 		[1] Diabetic cardiomyopathy 💬[2] 21, 86 💬
9 Elamipretide [1] Elamipretide[2] Elamipretide ,
Elamipretide hydrochloride 💬 		--[3] 18, 21, 324 💬
10 Flurbiprofen [1] Flurbiprofen[2] Flurbiprofen ,
Flurbiprofen sodium 💬 		[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[3] 13, 21, 46 💬
11 Glycerin [1] Glycerol[1] Glycerin 💬 --[10] 6, 7, 13, 21, 79, 265, 302, 316, 317, 344 💬
12 Idebenone [1] Idebenone[1] Idebenone 💬 --[7] 6, 8, 13, 18, 21, 113, 302 💬
13 KL1333 [1] KL1333---[1] 21 💬
14 L-arginine [1] L-arginine---[5] 2, 21, 46, 113, 299 💬
15 L-Glutamine [2] Glutamine; L-glutamine[1] Glutamine 💬 --[11] 21, 87, 89, 96, 97, 113, 214, 215, 222, 245, 299 💬
16 Lactose [1] Lactose[2] Anhydrous lactose ,
Lactose 💬 		--[7] 2, 6, 13, 21, 97, 228, 310 💬
17 Medium-chain triglycerides [2] Medium chain triglyceride; Medium-chain triglycerides[1] Triglycerides, medium-chain 💬 --[2] 21, 318 💬
18 Midazolam [1] Midazolam[3] Midazolam ,
Midazolam hydrochloride ,
Midazolam maleate 💬 		[16] GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRB,
GABRB,
GABRB,
GABRD,
GABRE,
GABRG,
GABRG,
GABRG,
GABRP,
GABRQ 💬 		[8] GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[13] 2, 3, 6, 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
19 Nicotinamide [2] Niacinamide; Nicotinamide[1] Niacinamide 💬 --[20] 2, 5, 6, 7, 8, 13, 17, 18, 21, 46, 49, 60, 63, 65, 67, 85, 97, 107, 162, 191 💬
20 Nicotinamide riboside [2] Nicotinamide riboside; Nicotinamide riboside chloride---[14] 2, 5, 6, 7, 8, 17, 18, 21, 49, 60, 65, 85, 97, 191 💬
21 Omeprazole [3] Omeprazol; Omeprazole; Omeprazole magnesium[3] Omeprazole ,
Omeprazole sodium ,
Omeprazole magnesium 💬 		[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[16] 6, 13, 21, 46, 51, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
22 Probucol [1] Probucol[1] Probucol 💬 --[3] 21, 66, 79 💬
23 Propofol [1] Propofol[1] Propofol 💬 [16] GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRB,
GABRB,
GABRB,
GABRD,
GABRE,
GABRG,
GABRG,
GABRG,
GABRP,
GABRQ 💬 		[8] GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[10] 3, 6, 21, 22, 34, 46, 70, 97, 98, 296 💬
24 Repaglinide [1] Repaglinide[1] Repaglinide 💬 [2] ABCC8,
KCNJ11 💬 		[4] ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬[4] 6, 21, 46, 299 💬
25 Sevoflurane [1] Sevoflurane[1] Sevoflurane 💬 --[8] 6, 21, 22, 34, 70, 98, 225, 296 💬
26 Sirolimus [2] Rapamycin; Sirolimus[1] Sirolimus 💬 [1] MTOR 💬 [49] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[46] 2, 6, 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 97, 98, 137, 157, 158, 192, 193, 222, 227, 256, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
27 Sonlicromanol [2] KH176; Sonlicromanol---[2] 21, 302 💬
28 Taurine [1] Taurine[1] Taurine 💬 --[4] 13, 21, 201, 337 💬
29 Uridine triacetate [1] TRI-O-acetyluridine[1] Uridine triacetate 💬 --[1] 21 💬
30 Vatiquinone [2] Alpha-tocotrienol quinone; Vatiquinone[1] Vatiquinone 💬 --[3] 18, 21, 156 💬
31 Zagociguat [0] [1] Zagociguat 💬 [3] GUCY1A,
GUCY1A,
GUCY1B 💬 		[10] Circadian entrainment, Gap junction, Long-term depression, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 21 💬