Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Acetic acid, glacial 💬[1] Acetic acid[1] Acetic acid--[3] 21, 97, 296 💬
2 Acetylcysteine 💬[1] Acetylcysteine[4] Acetylcysteine; N acetyl cysteine; N-Acetyl cysteine; N-Acetylcysteine--[25] 2, 6, 13, 19, 20, 21, 34, 49, 51, 53, 58, 63, 85, 90, 94, 97, 111, 164, 193, 233, 296, 298, 299, 303, 337 💬
3 Anhydrous lactose 💬[1] Lactose[2] Lactose; Lactose monohydrate--[8] 2, 6, 13, 21, 97, 107, 228, 310 💬
4 Arginine 💬[1] Arginine[1] Arginine--[16] 2, 21, 46, 57, 58, 67, 72, 96, 97, 98, 113, 210, 223, 225, 251, 299 💬
5 Arginine hydrochloride 💬[1] Arginine[1] Arginine--[16] 2, 21, 46, 57, 58, 67, 72, 96, 97, 98, 113, 210, 223, 225, 251, 299 💬
6 Arginine hydrochloride 💬[1] Arginine[1] Arginine--[16] 2, 21, 46, 57, 58, 67, 72, 96, 97, 98, 113, 210, 223, 225, 251, 299 💬
7 Bupropion 💬[1] Bupropion[2] Bupropion; Bupropion Hydrochloride[2] SLC6A2,
SLC6A3 💬 		[8] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Neuroactive ligand signaling, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[7] 8, 18, 21, 96, 97, 171, 298 💬
8 Bupropion hydrobromide 💬[1] Bupropion[2] Bupropion; Bupropion Hydrochloride[2] SLC6A2,
SLC6A3 💬 		[8] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Neuroactive ligand signaling, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[7] 8, 18, 21, 96, 97, 171, 298 💬
9 Bupropion hydrochloride 💬[1] Bupropion[2] Bupropion; Bupropion Hydrochloride[2] SLC6A2,
SLC6A3 💬 		[8] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Neuroactive ligand signaling, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[7] 8, 18, 21, 96, 97, 171, 298 💬
10 Caffeine 💬[1] Caffeine[1] Caffeine[11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬 		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 2, 6, 13, 21, 46, 96, 97, 265 💬
11 Caffeine citrate 💬[1] Caffeine[1] Caffeine[11] ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬 		[22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 2, 6, 13, 21, 46, 96, 97, 265 💬
12 Citrulline malate 💬[1] Citrulline[2] Citrulline; L-Citrulline--[3] 21, 86, 113 💬
13 Cysteamine 💬[1] Cysteamine[6] 2-aminoethanethiol; Cysteamine; Cysteamine bitartrate; CYSTEAMINE HYDROCHLORIDE; Mercaptamina; Mercaptamine--[4] 8, 19, 21, 299 💬
14 Cysteamine bitartrate 💬[1] Cysteamine[6] 2-aminoethanethiol; Cysteamine; Cysteamine Bitartrate; CYSTEAMINE HYDROCHLORIDE; Mercaptamina; Mercaptamine--[4] 8, 19, 21, 299 💬
15 Cysteamine hydrochloride 💬[1] Cysteamine[6] 2-aminoethanethiol; Cysteamine; Cysteamine bitartrate; CYSTEAMINE HYDROCHLORIDE; Mercaptamina; Mercaptamine--[4] 8, 19, 21, 299 💬
16 Dexmedetomidine 💬[1] Dexmedetomidine[4] DEXMEDETOMIDINA; DEXMEDETOMIDINE; DEXMEDETOMIDINE HYDROCHLORIDE; Imidazole[3] ADRA2A,
ADRA2B,
ADRA2C 💬 		[4] Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[15] 2, 4, 6, 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
17 Dexmedetomidine hydrochloride 💬[1] Dexmedetomidine[4] DEXMEDETOMIDINA; Dexmedetomidine; DEXMEDETOMIDINE HYDROCHLORIDE; Imidazole[3] ADRA2A,
ADRA2B,
ADRA2C 💬 		[4] Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[15] 2, 4, 6, 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
18 Dextromethorphan 💬[1] Dextromethorphan[2] Dextromethorphan; Dextromethorphan hydrobromide[6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬 		[21] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
19 Dextromethorphan hydrobromide 💬[1] Dextromethorphan[2] Dextromethorphan; DEXTROMETHORPHAN HYDROBROMIDE[6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬 		[21] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
20 Dextromethorphan polistirex 💬[1] Dextromethorphan[2] Dextromethorphan; DEXTROMETHORPHAN HYDROBROMIDE[6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬 		[21] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
21 Elamipretide 💬[1] Elamipretide[1] Elamipretide--[3] 18, 21, 324 💬
22 Elamipretide hydrochloride 💬[1] Elamipretide[1] Elamipretide--[3] 18, 21, 324 💬
23 Flurbiprofen 💬[1] Flurbiprofen[1] FLURBIPROFEN[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[3] 13, 21, 46 💬
24 Flurbiprofen sodium 💬[1] Flurbiprofen[1] Flurbiprofen[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[3] 13, 21, 46 💬
25 Idebenone 💬[1] Idebenone[1] IDEBENONE--[9] 6, 8, 13, 17, 18, 21, 113, 115, 302 💬
26 L-Citrulline 💬[1] Citrulline[2] Citrulline; L-Citrulline--[3] 21, 86, 113 💬
27 Lactose hydrate 💬[1] Lactose[2] Lactose; Lactose monohydrate--[8] 2, 6, 13, 21, 97, 107, 228, 310 💬
28 Mannitol 💬[1] Mannitol[3] D-Mannitol; Mannite; Mannitol--[8] 6, 13, 21, 28, 60, 96, 113, 299 💬
29 Midazolam 💬[1] Midazolam[1] Midazolam[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
30 Midazolam hydrochloride 💬[1] Midazolam[1] Midazolam[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
31 Midazolam maleate 💬[1] Midazolam[1] Midazolam[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
32 Niacinamide 💬[1] Nicotinamide[2] Niacinamide; Nicotinamide--[19] 2, 5, 6, 7, 8, 17, 18, 21, 46, 49, 60, 63, 65, 85, 97, 107, 162, 191, 302 💬
33 Omeprazole 💬[1] Omeprazole[3] Omeprazol; Omeprazole; OMEPRAZOLE MAGNESIUM[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[18] 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
34 Omeprazole magnesium 💬[1] Omeprazole[3] Omeprazol; Omeprazole; OMEPRAZOLE MAGNESIUM[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[18] 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
35 Omeprazole sodium 💬[1] Omeprazole[3] Omeprazol; Omeprazole; OMEPRAZOLE MAGNESIUM[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[18] 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
36 Probucol 💬[1] Probucol[1] Probucol--[4] 21, 66, 79, 223 💬
37 Propofol 💬[1] Propofol[1] Propofol[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[10] 3, 6, 21, 22, 34, 46, 70, 97, 98, 296 💬
38 Repaglinide 💬[1] Repaglinide[1] Repaglinide[2] ABCC8,
KCNJ11 💬 		[4] ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬[4] 6, 21, 46, 299 💬
39 Sevoflurane 💬[1] Sevoflurane[1] Sevoflurane--[8] 6, 21, 22, 34, 70, 98, 225, 296 💬
40 Sirolimus 💬[1] Sirolimus[2] Rapamycin; SIROLIMUS[1] MTOR 💬 [52] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, Integrated stress response (ISR) signaling pathway, Integrin signaling, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, Lysosome biogenesis, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[46] 6, 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 54, 57, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 97, 98, 111, 127, 137, 157, 158, 192, 222, 223, 227, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
41 Taurine 💬[1] Taurine[1] Taurine--[4] 13, 21, 201, 337 💬
42 Triglycerides, medium-chain 💬[1] Medium-chain triglycerides[1] Medium-Chain Triglycerides--[2] 21, 344 💬
43 Vatiquinone 💬[1] Vatiquinone[2] Alpha-tocotrienol quinone; VATIQUINONE--[2] 18, 21 💬
44 Zagociguat 💬[1] Zagociguat[1] Zagociguat[3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬 		[10] Circadian entrainment, Gap junction, Long-term depression, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 21 💬