Icon	Function
💬	A pop-up explanation appears when you mouse-over the text beside this icon. Also, an explanation window appears when you click this icon.
	The links beside this icon are links to external sites.
	Clicking this icon sorts the table by the item with this icon (Numerical or alphabetical order). Each click toggles between ascending and descending order.
	A text longer than 100 characters is fully displayed or collapsed.
	The contents of the displayed table are downloaded as a file named "table.csv".

KEGG DRUG

Search results

No.

Drug (Description in trials)

DrugBank

KEGG DRUG

KEGG GENES

KEGG PATHWAY

Disease ID

[RE-021]

[3] 66, 218, 222 💬

ACE I, ATA II and Statins

[1] 218 💬

ACE-inhibitor

[1] 218 💬

Ambrisentan

[1] Ambrisentan

[1] Ambrisentan 💬

[1] EDNRA 💬

[7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬

[10] 51, 66, 84, 85, 86, 88, 210, 211, 218, 222 💬

Disease ID	Name
51	Scleroderma
66	IgA nephropathy
84	Sarcoidosis
85	Idiopathic interstitial pneumonia
86	Pulmonary arterial hypertension
88	Chronic thromboembolic pulmonary hypertension
210	Single Ventricle
211	Hypoplastic left heart syndrome
218	Alport syndrome
222	Primary nephrotic syndrome

Angiotensin-receptor blocker (ARB)

[1] 218 💬

ATRASENTAN

[1] Atrasentan

[1] Atrasentan hydrochloride 💬

[1] EDNRA 💬

[3] 66, 218, 222 💬

Bardoxolone

[1] Bardoxolone

[1] Bardoxolone 💬

[7] 66, 67, 84, 85, 86, 218, 222 💬

Bardoxolone methyl

[2] Bardoxolone,
Bardoxolone methyl

[2] Bardoxolone ,
Bardoxolone methyl 💬

[7] 66, 67, 84, 85, 86, 218, 222 💬

BAY 3401016

[1] 218 💬

Benazepril

[1] Benazepril

[2] Benazepril hydrochloride ,
Benazepril 💬

[1] ACE 💬

[6] Chagas disease, Coronavirus disease, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬

[5] 49, 57, 218, 222, 224 💬

Benazepril hydrochloride 10 milligram (mg) Tab

[1] Benazepril

[2] Benazepril hydrochloride ,
Benazepril 💬

[1] ACE 💬

[6] Chagas disease, Coronavirus disease, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬

[1] 218 💬

Benazepril, Valsartan and Fluvastatin

[3] Benazepril,
Fluvastatin,
Valsartan

[5] Valsartan ,
Benazepril hydrochloride ,
Fluvastatin sodium ,
Benazepril ,
Fluvastatin 💬

[3] ACE,
AGTR1,
HMGCR 💬

[22] AGE-RAGE signaling pathway in diabetic complications, AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Bile secretion, Calcium signaling pathway, Chagas disease, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Hypertrophic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Terpenoid backbone biosynthesis, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬

[1] 218 💬

Dapagliflozin

[1] Dapagliflozin

[1] Dapagliflozin 💬

[16] 6, 19, 28, 40, 41, 49, 57, 66, 67, 86, 88, 97, 210, 215, 218, 222 💬

Disease ID	Name
6	Parkinson disease
19	Lysosomal storage disease
28	Systemic amyloidosis
40	Takayasu arteritis
41	Giant cell arteritis
49	Systemic lupus erythematosus
57	Idiopathic dilated cardiomyopathy
66	IgA nephropathy
67	Polycystic kidney disease
86	Pulmonary arterial hypertension
88	Chronic thromboembolic pulmonary hypertension
97	Ulcerative colitis
210	Single Ventricle
215	Tetralogy of Fallot
218	Alport syndrome
222	Primary nephrotic syndrome

Dapagliflozin 10mg Tab

[1] Dapagliflozin

[1] Dapagliflozin 💬

[4] 19, 97, 218, 222 💬

Delix

[1] 218 💬

ELX-02

[1] ELX-02

[3] 19, 218, 299 💬

Exaluren

[1] Exaluren

[1] 218 💬

Finerenone

[1] Finerenone

[1] Finerenone 💬

[1] NR3C2 💬

[1] Aldosterone-regulated sodium reabsorption 💬

[5] 66, 218, 222, 223, 224 💬

Fluvastatin

[1] Fluvastatin

[2] Fluvastatin sodium ,
Fluvastatin 💬

[1] HMGCR 💬

[3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬

[4] 48, 79, 218, 222 💬

Gold

[1] Gold

[71] 2, 5, 6, 11, 13, 17, 19, 21, 22, 28, 34, 35, 46, 49, 50, 53, 54, 56, 57, 58, 60, 63, 64, 65, 66, 68, 71, 75, 76, 77, 79, 84, 85, 86, 88, 91, 93, 95, 96, 97, 98, 107, 113, 127, 137, 158, 162, 167, 171, 193, 206, 215, 218, 222, 223, 224, 226, 227, 228, 230, 235, 271, 291, 294, 296, 298, 299, 310, 318, 331, 340 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
5	Progressive supranuclear palsy
6	Parkinson disease
11	Myasthenia gravis
13	Multiple sclerosis/Neuromyelitis optica
17	Multiple system atrophy
19	Lysosomal storage disease
21	Mitochondrial disease
22	Moyamoya disease
28	Systemic amyloidosis
34	Neurofibromatosis
35	Pemphigus
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
50	Dermatomyositis
53	Sjogren syndrome
54	Adult still disease
56	Behcet disease
57	Idiopathic dilated cardiomyopathy
58	Hypertrophic cardiomyopathy
60	Aplastic anemia
63	Idiopathic thrombocytopenic purpura
64	Thrombotic thrombocytopenic purpura
65	Primary immunodeficiency
66	IgA nephropathy
68	Ossification of the ligamentum flavum
71	Idiopathic osteonecrosis of the femoral head
75	Cushing disease
76	Pituitary gonadotropin secretion hyperthyroidism
77	Growth hormone secreting pituitary adenoma
79	Homozygous familial hypercholesterolemia
84	Sarcoidosis
85	Idiopathic interstitial pneumonia
86	Pulmonary arterial hypertension
88	Chronic thromboembolic pulmonary hypertension
91	Budd-Chiari syndrome
93	Primary biliary cholangitis
95	Autoimmune hepatitis
96	Crohn disease
97	Ulcerative colitis
98	Eosinophilic gastro-intestinal disorder
107	Juvenile idiopathic arthritis
113	Muscular dystrophy
127	Frontotemporal lobar degeneration
137	Focal cortical dysplasia
158	Tuberous sclerosis
162	Pemphigoid
167	Marfan syndrome
171	Wilson disease
193	Prader-Willi syndrome
206	Fragile X syndrome
215	Tetralogy of Fallot
218	Alport syndrome
222	Primary nephrotic syndrome
223	Primary membranoproliferative glomerulonephritis
224	Purpura nephritis
226	Interstitial cystitis with Hunners ulcer
227	Osler disease
228	Bronchiolitis obliterans
230	Alveolar hypoventilation syndrome
235	Hypoparathyroidism
271	Ankylosing spondylitis
291	Hirschsprung disease, entire colon type
294	Congenital diaphragmatic hernia
296	Biliary atresia
298	Hereditary pancreatitis
299	Cystic fibrosis
310	Congenital anomalies syndrome
318	Citrin deficiency
331	Idiopathic multicentric castleman disease
340	Primary ciliary dyskinesia

Henagliflozin

[1] Henagliflozin

[3] 58, 66, 218 💬

HMG-Coenzyme inhibitor (statin)

[1] 218 💬

HUC-MSC

[1] 218 💬

Hydroxychloroquine

[1] Hydroxychloroquine

[2] Hydroxychloroquine sulfate ,
Hydroxychloroquine 💬

[29] 6, 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 223, 224, 234, 254, 271, 298, 299 💬

Disease ID	Name
6	Parkinson disease
13	Multiple sclerosis/Neuromyelitis optica
34	Neurofibromatosis
41	Giant cell arteritis
43	Microscopic polyangiitis
44	Wegener granulomatosis
45	Eosinophilic granulomatosis with Polyangiitis
46	Malignant rheumatoid arthritis
48	Primary antiphospholipid syndrome
49	Systemic lupus erythematosus
53	Sjogren syndrome
56	Behcet disease
63	Idiopathic thrombocytopenic purpura
66	IgA nephropathy
84	Sarcoidosis
89	Lymphangioleiomyomatosis
90	Retinitis pigmentosa
96	Crohn disease
97	Ulcerative colitis
107	Juvenile idiopathic arthritis
218	Alport syndrome
222	Primary nephrotic syndrome
223	Primary membranoproliferative glomerulonephritis
224	Purpura nephritis
234	Peroxisomal disease (except Adrenoleukodystrophy)
254	Porphyria
271	Ankylosing spondylitis
298	Hereditary pancreatitis
299	Cystic fibrosis

Hydroxychloroquine Sulfate 100 milligram (mg) Tab

[1] Hydroxychloroquine

[2] Hydroxychloroquine sulfate ,
Hydroxychloroquine 💬

[1] 218 💬

Lademirsen

[1] Lademirsen

[1] 218 💬

Lademirsen (SAR339375)

[1] Lademirsen

[1] 218 💬

Metformin

[1] Metformin

[2] Metformin hydrochloride ,
Metformin 💬

Name	Other Names
Metformin hydrochloride	Glucophage GLUMETZA RIOMET METFORMIN METFORMIN ER 500 MG METFORMIN HCL METFORMIN HYDROCHLORIDE EXTENDED RELEASE METFORMIN HYDROCHLORIDE EXTENDED-RELEASE 500MG METFORMIN HYDROCHLORIDE ORAL SOLUTION
Metformin	Metformin

[2] PRKAA1,
PRKAA2 💬

[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬

[31] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
6	Parkinson disease
8	Huntington disease
13	Multiple sclerosis/Neuromyelitis optica
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
60	Aplastic anemia
65	Primary immunodeficiency
66	IgA nephropathy
67	Polycystic kidney disease
74	Prolactin secreting pituitary adenoma
75	Cushing disease
77	Growth hormone secreting pituitary adenoma
81	Congenital adrenal hyperplasia
84	Sarcoidosis
85	Idiopathic interstitial pneumonia
86	Pulmonary arterial hypertension
97	Ulcerative colitis
113	Muscular dystrophy
127	Frontotemporal lobar degeneration
158	Tuberous sclerosis
206	Fragile X syndrome
218	Alport syndrome
222	Primary nephrotic syndrome
225	Congenital nephrogenic diabetes insipidus
233	Wolfram syndrome
265	Lipodystrophy
285	Fanconi anemia
298	Hereditary pancreatitis
299	Cystic fibrosis
301	Macular dystrophy

Paricalcitol

[1] Paricalcitol

[1] Paricalcitol 💬

[1] VDR 💬

[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬

[5] 19, 66, 218, 238, 298 💬

R3R01

[1] R3R01

[2] 218, 222 💬

Ramipril

[1] Ramipril

[1] Ramipril 💬

[1] ACE 💬

[6] Chagas disease, Coronavirus disease, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬

[10] 46, 49, 57, 66, 67, 113, 218, 222, 223, 257 💬

Disease ID	Name
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
57	Idiopathic dilated cardiomyopathy
66	IgA nephropathy
67	Polycystic kidney disease
113	Muscular dystrophy
218	Alport syndrome
222	Primary nephrotic syndrome
223	Primary membranoproliferative glomerulonephritis
257	Hepatic glycogenosis

[3] 66, 218, 222 💬

[1] 218 💬

[1] 218 💬

[3] 67, 86, 218 💬

[1] 218 💬

[1] Setanaxib

[2] 93, 218 💬

SGLT2 inhibitor

[2] 113, 218 💬

SPARSENTAN

[1] Sparsentan

[1] Sparsentan 💬

[2] AGTR1,
EDNRA 💬

[18] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬

[4] 66, 218, 222, 223 💬

Spironolactone

[1] Spironolactone

[1] Spironolactone 💬

[1] NR3C2 💬

[1] Aldosterone-regulated sodium reabsorption 💬

[12] 46, 57, 58, 67, 86, 113, 210, 214, 218, 222, 223, 225 💬

Disease ID	Name
46	Malignant rheumatoid arthritis
57	Idiopathic dilated cardiomyopathy
58	Hypertrophic cardiomyopathy
67	Polycystic kidney disease
86	Pulmonary arterial hypertension
113	Muscular dystrophy
210	Single Ventricle
214	Pulmonary atresia with ventricular septum defect
218	Alport syndrome
222	Primary nephrotic syndrome
223	Primary membranoproliferative glomerulonephritis
225	Congenital nephrogenic diabetes insipidus

Spironolactone or Finerenone

[2] Finerenone,
Spironolactone

[2] Spironolactone ,
Finerenone 💬

[1] NR3C2 💬

[1] Aldosterone-regulated sodium reabsorption 💬

[1] 218 💬

Treatment with Dapagliflozin followed by Spironolactone followed by their combination

[2] Dapagliflozin,
Spironolactone

[2] Spironolactone ,
Dapagliflozin 💬

[1] NR3C2 💬

[1] Aldosterone-regulated sodium reabsorption 💬

[1] 218 💬

Treatment with Spironolactone followed by Dapagliflozin followed by their combination

[2] Dapagliflozin,
Spironolactone

[2] Spironolactone ,
Dapagliflozin 💬

[1] NR3C2 💬

[1] Aldosterone-regulated sodium reabsorption 💬

[1] 218 💬

Valsartan

[1] Valsartan

[1] Valsartan 💬

[1] AGTR1 💬

[17] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬

[11] 28, 57, 58, 66, 75, 86, 210, 218, 222, 223, 224 💬

Disease ID	Name
28	Systemic amyloidosis
57	Idiopathic dilated cardiomyopathy
58	Hypertrophic cardiomyopathy
66	IgA nephropathy
75	Cushing disease
86	Pulmonary arterial hypertension
210	Single Ventricle
218	Alport syndrome
222	Primary nephrotic syndrome
223	Primary membranoproliferative glomerulonephritis
224	Purpura nephritis

Vonafexor

[1] Vonafexor

[1] 218 💬