Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Angiotensin II [2] Angiotensin; Angiotensin II[3] Angiotensin II ,
Angiotensin II ,
Angiotensin II acetate 💬 		[2] AGTR1,
AGTR2 💬 		[17] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[7] 17, 46, 49, 66, 218, 222, 224 💬
2 Atrasentan [1] Atrasentan[1] Atrasentan hydrochloride 💬 [1] EDNRA 💬 [7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 66, 218, 222 💬
3 Bardoxolone [0] [1] Bardoxolone 💬 --[7] 66, 67, 84, 85, 86, 218, 222 💬
4 Bardoxolone methyl [1] Bardoxolone methyl[1] Bardoxolone methyl 💬 --[7] 66, 67, 84, 85, 86, 218, 222 💬
5 Benazepril [1] Benazepril[2] Benazepril hydrochloride ,
Benazepril 💬 		[1] ACE 💬 [6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[4] 49, 57, 218, 224 💬
6 Dapagliflozin [1] Dapagliflozin[1] Dapagliflozin 💬 --[13] 6, 19, 28, 49, 66, 67, 86, 88, 97, 210, 215, 218, 222 💬
7 ELX-02 [1] ELX-02---[3] 19, 218, 299 💬
8 Finerenone [1] Finerenone[1] Finerenone 💬 [1] NR3C2 💬 [1] Aldosterone-regulated sodium reabsorption 💬[4] 66, 218, 222, 224 💬
9 Henagliflozin [1] Henagliflozin---[2] 66, 218 💬
10 Hydroxychloroquine [2] Hydroxychloroquine; Hydroxychloroquine sulfate[2] Hydroxychloroquine sulfate ,
Hydroxychloroquine 💬 		--[27] 6, 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 90, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299 💬
11 Lademirsen [1] Lademirsen---[1] 218 💬
12 Metformin [3] Metformin; Metformin hydrochloride; Metformina[2] Metformin hydrochloride ,
Metformin 💬 		[2] PRKAA,
PRKAA 💬 		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[28] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬
13 Paricalcitol [1] Paricalcitol[1] Paricalcitol 💬 [1] VDR 💬 [5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[5] 19, 66, 218, 238, 298 💬
14 R3R01 [1] R3r01---[2] 218, 222 💬
15 Ramipril [1] Ramipril[1] Ramipril 💬 [1] ACE 💬 [6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[7] 46, 49, 66, 67, 113, 218, 257 💬
16 Setanaxib [1] Setanaxib---[2] 93, 218 💬
17 Sparsentan [1] Sparsentan[1] Sparsentan 💬 [2] AGTR1,
EDNRA 💬 		[18] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 66, 218, 222 💬
18 Spironolactone [1] Spironolactone[1] Spironolactone 💬 [1] NR3C2 💬 [1] Aldosterone-regulated sodium reabsorption 💬[8] 46, 58, 67, 86, 113, 210, 218, 225 💬
19 Vonafexor [1] Vonafexor---[1] 218 💬