Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Angiotensin II 💬[1] Angiotensin II[2] Angiotensin; Angiotensin II[2] AGTR1,
AGTR2 💬 		[17] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[5] 17, 66, 218, 222, 224 💬
2 Angiotensin II 💬[1] Angiotensin II[2] Angiotensin; Angiotensin II[2] AGTR1,
AGTR2 💬 		[17] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[5] 17, 66, 218, 222, 224 💬
3 Angiotensin II acetate 💬[1] Angiotensin II[2] Angiotensin; Angiotensin II[2] AGTR1,
AGTR2 💬 		[17] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[5] 17, 66, 218, 222, 224 💬
4 Atrasentan hydrochloride 💬[1] Atrasentan[1] Atrasentan[1] EDNRA 💬 [7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 66, 218, 222 💬
5 Bardoxolone 💬[1] Bardoxolone[0] ---
6 Bardoxolone methyl 💬[1] Bardoxolone methyl[1] Bardoxolone methyl--[5] 67, 84, 85, 86, 218 💬
7 Benazepril 💬[1] Benazepril[1] Benazepril[1] ACE 💬 [6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[2] 57, 218 💬
8 Benazepril hydrochloride 💬[1] Benazepril[1] Benazepril[1] ACE 💬 [6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[2] 57, 218 💬
9 Dapagliflozin 💬[1] Dapagliflozin[1] Dapagliflozin--[10] 6, 28, 49, 66, 67, 86, 88, 215, 218, 222 💬
10 Finerenone 💬[1] Finerenone[1] Finerenone[1] NR3C2 💬 [1] Aldosterone-regulated sodium reabsorption 💬[4] 66, 218, 222, 224 💬
11 Hydroxychloroquine 💬[1] Hydroxychloroquine[2] Hydroxychloroquine; Hydroxychloroquine sulfate--[26] 6, 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299 💬
12 Hydroxychloroquine sulfate 💬[1] Hydroxychloroquine[2] Hydroxychloroquine; Hydroxychloroquine sulfate--[26] 6, 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299 💬
13 Metformin 💬[1] Metformin[3] Metformin; Metformin hydrochloride; Metformina[2] PRKAA,
PRKAA 💬 		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[27] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 225, 265, 285, 298, 299, 301 💬
14 Metformin hydrochloride 💬[1] Metformin[3] Metformin; Metformin hydrochloride; Metformina[2] PRKAA,
PRKAA 💬 		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[27] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 225, 265, 285, 298, 299, 301 💬
15 Paricalcitol 💬[1] Paricalcitol[1] Paricalcitol[1] VDR 💬 [5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[5] 19, 66, 218, 238, 298 💬
16 Ramipril 💬[1] Ramipril[1] Ramipril[1] ACE 💬 [6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[7] 46, 49, 66, 67, 113, 218, 257 💬
17 Sparsentan 💬[1] Sparsentan[1] Sparsentan[2] AGTR1,
EDNRA 💬 		[18] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 66, 218, 222 💬
18 Spironolactone 💬[1] Spironolactone[1] Spironolactone[1] NR3C2 💬 [1] Aldosterone-regulated sodium reabsorption 💬[7] 46, 58, 67, 86, 113, 210, 225 💬