Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1(4S,5R)-5-[3,5-bis(trifluoromethyl)phenyl]-3-{[4’-----[1] 79 💬
20.9% NaCl----[1] 79 💬
31,2-Dihexadecanoyl-sn-Glycero-3-Phospho-(1-raac-glycerol)----[1] 79 💬
42-[3,5-Dichloro-4-(5-isopropyl-6-oxo-1,6-dihydro-pyridazin-3-yloxy)- phenyl]-3,5-dioxo-2,3,4,5-tetrahydro-[1,2,4]triazine-6-carbonitrile----[1] 79 💬
52-Hydroxybenzylamine----[1] 79 💬
6: [R-(R*, R*)]-2-(4-fluorophenyl)-beta, ?-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbony----[1] 79 💬
7: [R-(R*, R*)]-2-(4-fluorophenyl)-ß, ?-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbony----[1] 79 💬
8[AMG 145]----[1] 79 💬
9[KJX839]----[1] 79 💬
10[Lomitapide 2mg hard capsules][1] Lomitapide[2] Lomitapide ,
Lomitapide mesylate 💬 		[1] MTTP 💬 [1] Fat digestion and absorption 💬[1] 79 💬
11[NA]----[34] 3, 6, 11, 13, 14, 19, 28, 35, 41, 46, 49, 50, 53, 57, 62, 63, 65, 75, 79, 85, 90, 96, 97, 98, 113, 127, 162, 195, 223, 229, 251, 294, 299, 302 💬
12[PRD7255830]----[1] 79 💬
13[PRD7255977]----[1] 79 💬
14[PRD7256003]----[1] 79 💬
15[R-(R*, R*)]-2-(4-fluorophenyl)-beta, ?-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-----[1] 79 💬
16[R-(R*, R*)]-2-(4-fluorophenyl)-ß, ?-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-----[1] 79 💬
17[R727]----[1] 79 💬
18[REGN1500]----[1] 79 💬
19[REGN7272]----[1] 79 💬
20AAV directed hLDLR gene therapy----[1] 79 💬
21AAV8.TBG.hLDLR----[1] 79 💬
22Acetate[1] Acetate---[52] 1, 2, 6, 10, 11, 13, 22, 35, 40, 46, 49, 51, 60, 63, 64, 65, 66, 67, 70, 71, 73, 75, 76, 77, 78, 79, 81, 83, 85, 86, 88, 89, 90, 96, 97, 113, 145, 156, 158, 162, 171, 206, 222, 223, 224, 225, 227, 235, 251, 265, 298, 299 💬
23AEGR-733----[1] 79 💬
24AK102----[1] 79 💬
25AKCEA-ANGPTL3-LRX----[2] 79, 265 💬
26ALIROCUMAB[1] Alirocumab[1] Alirocumab 💬 [1] PCSK9 💬 [1] Cholesterol metabolism 💬[1] 79 💬
27Alirocumab SAR236553 (REGN727)[1] Alirocumab[1] Alirocumab 💬 [1] PCSK9 💬 [1] Cholesterol metabolism 💬[1] 79 💬
28ALN-60212----[1] 79 💬
29ALN-PCSSC----[1] 79 💬
30AMG 145----[1] 79 💬
31AMG145----[1] 79 💬
32Amlodipine[1] Amlodipine[4] Amlodipine besylate ,
Amlodipine maleate ,
Amlodipine ,
Amlodipine benzoate 💬 		[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 51, 67, 79, 113, 222, 298 💬
33Amlodipine/Atorvastatin[2] Amlodipine,
Atorvastatin		[6] Amlodipine besylate ,
Atorvastatin calcium ,
Amlodipine maleate ,
Amlodipine ,
Atorvastatin ,
Amlodipine benzoate 💬 		[5] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
HMGCR 💬 		[40] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Bile secretion, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Terpenoid backbone biosynthesis, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 79 💬
34ANACETRAPIB[1] Anacetrapib[1] Anacetrapib 💬 [1] CETP 💬 [1] Cholesterol metabolism 💬[1] 79 💬
35APL180----[1] 79 💬
36ARO-ANG 3 Injection----[1] 79 💬
37ARO-ANG3----[1] 79 💬
38ART002g1 Injection----[1] 79 💬
39At----[1] 79 💬
40Atorvastatin[1] Atorvastatin[2] Atorvastatin calcium ,
Atorvastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[21] 13, 22, 46, 49, 51, 58, 63, 67, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
41Atorvastatin (approved)[1] Atorvastatin[2] Atorvastatin calcium ,
Atorvastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[1] 79 💬
42Atorvastatin (Lipitor)[1] Atorvastatin[2] Atorvastatin calcium ,
Atorvastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[1] 79 💬
43Atorvastatin (Lipitor)(Zarator in Iceland)[1] Atorvastatin[2] Atorvastatin calcium ,
Atorvastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[1] 79 💬
44Atorvastatin ,Zarator[1] Atorvastatin[2] Atorvastatin calcium ,
Atorvastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[1] 79 💬
45ATORVASTATIN CALCIUM[2] Atorvastatin,
Calcium		[2] Atorvastatin calcium ,
Atorvastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[3] 79, 97, 265 💬
46Atorvastatin/ Zarator[1] Atorvastatin[2] Atorvastatin calcium ,
Atorvastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[1] 79 💬
47Atorvastatina----[1] 79 💬
48ATORVASTATINA CALCICA TRIHIDRATO----[1] 79 💬
49AZD0780----[1] 79 💬
50AZD4522----[1] 79 💬
51Behavioral: Cascade screening----[1] 79 💬
52Behavioral: Direct contact of family members for cascade screening of relevant variants----[1] 79 💬
53Behavioral: Maintenance of specific diet----[1] 79 💬
54Behavioral: Motivational Counseling----[1] 79 💬
55Bempedoic acid[1] Bempedoic acid[1] Bempedoic acid 💬 [1] ACLY 💬 [1] Citrate cycle (TCA cycle) 💬[2] 67, 79 💬
56Bempedoic acid 180mg Tablets[1] Bempedoic acid[1] Bempedoic acid 💬 [1] ACLY 💬 [1] Citrate cycle (TCA cycle) 💬[1] 79 💬
57Blood sample----[33] 2, 3, 6, 8, 10, 13, 14, 19, 34, 46, 48, 49, 51, 53, 61, 63, 65, 66, 67, 77, 79, 84, 88, 96, 97, 107, 113, 127, 195, 206, 235, 274, 299 💬
58Blood test----[19] 2, 6, 13, 36, 46, 49, 51, 74, 79, 83, 96, 113, 127, 162, 227, 256, 280, 299, 300 💬
59BMS356384----[1] 79 💬
60Bococizumab[1] Bococizumab[1] Bococizumab 💬 [1] PCSK9 💬 [1] Cholesterol metabolism 💬[1] 79 💬
61Bococizumab (PF-04950615[1] Bococizumab[1] Bococizumab 💬 [1] PCSK9 💬 [1] Cholesterol metabolism 💬[1] 79 💬
62Calcium[1] Calcium---[39] 2, 3, 6, 13, 15, 19, 46, 48, 49, 51, 53, 56, 62, 67, 68, 71, 74, 75, 79, 84, 90, 93, 94, 95, 96, 97, 156, 186, 214, 215, 222, 224, 235, 256, 265, 271, 274, 298, 299 💬
63Calcium rosuvastatin[2] Calcium,
Rosuvastatin		[2] Rosuvastatin calcium ,
Rosuvastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[1] 79 💬
64CARDYL 10 mg comprimidos recubiertos con película----[1] 79 💬
65CARDYL 20 mg comprimidos recubiertos con película----[1] 79 💬
66CARDYL 40 mg comprimidos recubiertos con película----[1] 79 💬
67CER-001[1] CER-001---[1] 79 💬
68Chemical name: [R-(R*, R*)]-2-(4-fluorophenyl)-beta, ?-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenyl----[1] 79 💬
69Chemical name: [R-(R*, R*)]-2-(4-fluorophenyl)-ß, ?-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenyl----[1] 79 💬
70Cholestagel----[2] 79, 96 💬
71Cholesterol[1] Cholesterol[1] Cholesterol 💬 --[10] 8, 19, 71, 79, 90, 160, 222, 259, 261, 310 💬
72Cholestyramine[1] Cholestyramine[1] Cholestyramine resin 💬 --[2] 13, 79 💬
73CION-08 Concentration unit: mg milligram(s)Concentration type: equalConcentration number: 60-Product Name: bempedoic acidPharmaceutical Form: Suspension for oral suspensionINN or Proposed INN: Bempedoic acidCAS Number: 738606-46-7 Concentration unit: mg/ml milligram(s)/millilitreConcentration type: equalConcentration number: 20-----[1] 79 💬
74CION-08 Concentration unit: mg milligram(s)Concentration type: equalConcentration number: 90-Trade Name: Nilemdo Product Name: bempedoic acidPharmaceutical Form: TabletINN or Proposed INN: Bempedoic acidCAS Number: 738606-46-7 Current Sponsor code: ETC-1002----[1] 79 💬
75Colesevelam[1] Colesevelam[2] Colesevelam hydrochloride ,
Colesevelam 💬 		--[3] 79, 96, 260 💬
76Colesevelam HCl[1] Colesevelam[2] Colesevelam hydrochloride ,
Colesevelam 💬 		--[1] 79 💬
77Colesevelam hydrochloride[1] Colesevelam[2] Colesevelam hydrochloride ,
Colesevelam 💬 		--[1] 79 💬
78Colesevelam hydrochloride film-coated tablets[1] Colesevelam[2] Colesevelam hydrochloride ,
Colesevelam 💬 		--[1] 79 💬
79Combination Product: Combination Therapy----[1] 79 💬
80Comparator: ezetimibe[1] Ezetimibe[1] Ezetimibe 💬 [1] NPC1L1 💬 [1] Fat digestion and absorption 💬[2] 79, 260 💬
81Comparator: niacin (+) laropiprant (MK0524A)[2] Laropiprant,
Niacin		[2] Niacin ,
Laropiprant 💬 		[1] PTGDR 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 79 💬
82CP-529,414/Atorvastatin[1] Atorvastatin[2] Atorvastatin calcium ,
Atorvastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[1] 79 💬
83Crestor----[3] 49, 79, 299 💬
84CRESTOR 10 mg encapsulated tablet----[1] 79 💬
85CRESTOR 20 mg encapsulated tablet (2x10 mg)----[1] 79 💬
86CRESTOR 5 mg encapsulated tablet----[1] 79 💬
87Crestor Film-Coated Tablet----[1] 79 💬
88Crestor Tablets (calcium rosuvastatin) Film-Coated tablets[2] Calcium,
Rosuvastatin		[2] Rosuvastatin calcium ,
Rosuvastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[1] 79 💬
89CTX310----[1] 79 💬
90Current lipid-lowering treatment----[1] 79 💬
91Dextran[1] Dextran[5] Dextran 1 ,
Dextran sulfate sodium ,
Dextran 40 ,
Dextran 70 ,
Dextran 75 💬 		[2] LIPC,
LPL 💬 		[4] Alzheimer disease, Cholesterol metabolism, Glycerolipid metabolism, PPAR signaling pathway 💬[5] 2, 62, 79, 96, 97 💬
92Dextran sulfate adsorption[1] Dextran[5] Dextran 1 ,
Dextran sulfate sodium ,
Dextran 40 ,
Dextran 70 ,
Dextran 75 💬 		[2] LIPC,
LPL 💬 		[4] Alzheimer disease, Cholesterol metabolism, Glycerolipid metabolism, PPAR signaling pathway 💬[1] 79 💬
93Diagnostic Test: Lipid analysis----[1] 79 💬
94DPPG----[1] 79 💬
95EDP167----[1] 79 💬
96Enlicitide Decanoate----[1] 79 💬
97Eprotirome[1] Eprotirome---[1] 79 💬
98ER Niacin/Laropiprant[2] Laropiprant,
Niacin		[2] Niacin ,
Laropiprant 💬 		[1] PTGDR 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 79 💬
99ER-Niacin or Niacin[1] Niacin[1] Niacin 💬 --[1] 79 💬
100ESP55016----[1] 79 💬
101ETC-1002----[1] 79 💬
102ETC-1002 180mg Tablets----[1] 79 💬
103EVINACUMAB[1] Evinacumab[1] Evinacumab 💬 [1] ANGPTL3 💬 [1] Cholesterol metabolism 💬[1] 79 💬
104Evinacumab (REGN1500)[1] Evinacumab[1] Evinacumab 💬 [1] ANGPTL3 💬 [1] Cholesterol metabolism 💬[1] 79 💬
105EVOLOCUMAB[1] Evolocumab[1] Evolocumab 💬 [1] PCSK9 💬 [1] Cholesterol metabolism 💬[2] 79, 222 💬
106Extended Release Niacin / Laropiprant[2] Laropiprant,
Niacin		[2] Niacin ,
Laropiprant 💬 		[1] PTGDR 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 79 💬
107EZ 10 mg/Atorva 10 mg FDC----[1] 79 💬
108EZ 10 mg/Atorva 20 mg FDC----[1] 79 💬
109EZE----[1] 79 💬
110Ezetimibe[1] Ezetimibe[1] Ezetimibe 💬 [1] NPC1L1 💬 [1] Fat digestion and absorption 💬[5] 49, 79, 93, 149, 260 💬
111Ezetimibe (plus simvastatin)[2] Ezetimibe,
Simvastatin		[2] Simvastatin ,
Ezetimibe 💬 		[2] HMGCR,
NPC1L1 💬 		[4] AMPK signaling pathway, Bile secretion, Fat digestion and absorption, Terpenoid backbone biosynthesis 💬[1] 79 💬
112Ezetimibe (sp)[1] Ezetimibe[1] Ezetimibe 💬 [1] NPC1L1 💬 [1] Fat digestion and absorption 💬[1] 79 💬
113Ezetimibe + other lipid-lowering medication(s)[1] Ezetimibe[1] Ezetimibe 💬 [1] NPC1L1 💬 [1] Fat digestion and absorption 💬[2] 79, 260 💬
114Ezetimibe with simvastatin[2] Ezetimibe,
Simvastatin		[2] Simvastatin ,
Ezetimibe 💬 		[2] HMGCR,
NPC1L1 💬 		[4] AMPK signaling pathway, Bile secretion, Fat digestion and absorption, Terpenoid backbone biosynthesis 💬[1] 79 💬
115EZETROL----[3] 79, 93, 260 💬
116Fenofibrate[1] Fenofibrate[1] Fenofibrate 💬 [1] PPARA 💬 [10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[6] 8, 79, 93, 94, 97, 265 💬
117Fish Oil[1] Fish oil---[10] 13, 46, 49, 50, 66, 79, 96, 260, 294, 299 💬
118Fish oil capsule[1] Fish oil---[1] 79 💬
119Fluvastatin[1] Fluvastatin[2] Fluvastatin sodium ,
Fluvastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[4] 48, 79, 218, 222 💬
120Gemcabene[1] Gemcabene---[2] 79, 265 💬
121Genetic: Control - No Result----[1] 79 💬
122Genetic: Gene analysis----[1] 79 💬
123Genetic: Genetic----[1] 79 💬
124Genetic: Genetic Testing----[5] 79, 89, 90, 158, 299 💬
125Genetic: Next generation sequencing (NGS)----[1] 79 💬
126Genetic: NGGT006----[1] 79 💬
127Genetic: Receive a pediatric-onset result----[1] 79 💬
128Genetic: Receive an adult-onset result----[1] 79 💬
129Genetic: whole genome sequencing----[3] 6, 79, 172 💬
130Gold[1] Gold---[71] 2, 5, 6, 11, 13, 17, 19, 21, 22, 28, 34, 35, 46, 49, 50, 53, 54, 56, 57, 58, 60, 63, 64, 65, 66, 68, 71, 75, 76, 77, 79, 84, 85, 86, 88, 91, 93, 95, 96, 97, 98, 107, 113, 127, 137, 158, 162, 167, 171, 193, 206, 215, 218, 222, 223, 224, 226, 227, 228, 230, 235, 271, 291, 294, 296, 298, 299, 310, 318, 331, 340 💬
131GZ402661----[1] 79 💬
132Heparin[1] Heparin[2] Heparin sodium ,
Heparin calcium 💬 		[1] SERPINC1 💬 [1] Complement and coagulation cascades 💬[15] 47, 48, 60, 65, 70, 79, 84, 107, 224, 226, 280, 299, 316, 317, 344 💬
133Heparin-induced extracorporeal LDL precipitation[1] Heparin[2] Heparin sodium ,
Heparin calcium 💬 		[1] SERPINC1 💬 [1] Complement and coagulation cascades 💬[1] 79 💬
134HMG Coenzyme reductase----[1] 79 💬
135IBI306----[1] 79 💬
136IBI306 450mg SC Q4W----[1] 79 💬
137IBI306 600mg SC Q6W----[1] 79 💬
138Implitapide[1] Implitapide---[1] 79 💬
139INCLISIRAN[1] Inclisiran[2] Inclisiran ,
Inclisiran sodium 💬 		[1] PCSK9 💬 [1] Cholesterol metabolism 💬[1] 79 💬
140Inclisiran (Leqvio®) 300mg[1] Inclisiran[2] Inclisiran ,
Inclisiran sodium 💬 		[1] PCSK9 💬 [1] Cholesterol metabolism 💬[1] 79 💬
141Inclisiran for Injection[1] Inclisiran[2] Inclisiran ,
Inclisiran sodium 💬 		[1] PCSK9 💬 [1] Cholesterol metabolism 💬[1] 79 💬
142Inclisiran Sodium[1] Inclisiran[2] Inclisiran ,
Inclisiran sodium 💬 		[1] PCSK9 💬 [1] Cholesterol metabolism 💬[1] 79 💬
143Inclisiran Sodium for injection[1] Inclisiran[2] Inclisiran ,
Inclisiran sodium 💬 		[1] PCSK9 💬 [1] Cholesterol metabolism 💬[1] 79 💬
144IONIS ANGPTL3-LRx----[1] 79 💬
145ISIS 301012----[1] 79 💬
146ISIS 301012 phosphorothioate oligonucleotide----[1] 79 💬
147ISIS 703802----[1] 79 💬
148JS002----[1] 79 💬
149KB2115----[1] 79 💬
150KJX839----[1] 79 💬
151Krill oil[1] Krill oil---[1] 79 💬
152Kynamro----[1] 79 💬
153Lactobacillus paracasei[1] Lactobacillus paracasei---[1] 79 💬
154Lactobacillus paracasei B21060[1] Lactobacillus paracasei---[1] 79 💬
155Lapaquistat[1] Lapaquistat---[1] 79 💬
156Lapaquistat acetate and current lipid-lowering treatment[2] Acetate,
Lapaquistat		---[1] 79 💬
157Laropiprant[1] Laropiprant[1] Laropiprant 💬 [1] PTGDR 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 79 💬
158Leqvio----[1] 79 💬
159Leqvio 284 mg solution for injection in pre-filled syringe----[1] 79 💬
160Lerodalcibep[1] Lerodalcibep[1] Lerodalcibep 💬 [1] PCSK9 💬 [1] Cholesterol metabolism 💬[1] 79 💬
161Lerodalcibep 300 mg Monthly SC[1] Lerodalcibep[1] Lerodalcibep 💬 [1] PCSK9 💬 [1] Cholesterol metabolism 💬[1] 79 💬
162LIB003----[1] 79 💬
163Lipid Modifying Therapy (LMT)----[1] 79 💬
164Lipid-lowering treatments----[1] 79 💬
165Lipid-Modifying Therapy (LMT)----[1] 79 💬
166Lipitor----[4] 51, 79, 96, 299 💬
167Livazo 1 mg film-coated tablets----[1] 79 💬
168Livazo 1mg film-coated tablets----[1] 79 💬
169Livazo 2 mg film-coated tablets----[1] 79 💬
170Livazo 2mg film-coated tablets----[1] 79 💬
171Livazo 4 mg film-coated tablets----[1] 79 💬
172Livazo 4mg film-coated tablets----[1] 79 💬
173LMT (atorvastatin, simvastatin, or rosuvastatin)[3] Atorvastatin,
Rosuvastatin,
Simvastatin		[5] Simvastatin ,
Rosuvastatin calcium ,
Atorvastatin calcium ,
Atorvastatin ,
Rosuvastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[1] 79 💬
174Lojuxta 10 mg hard capsules----[1] 79 💬
175Lojuxta 20 mg hard capsules----[1] 79 💬
176Lojuxta 5 mg hard capsules----[1] 79 💬
177LOMITAPIDE[1] Lomitapide[2] Lomitapide ,
Lomitapide mesylate 💬 		[1] MTTP 💬 [1] Fat digestion and absorption 💬[1] 79 💬
178Lomitapide 2mg hard capsules[1] Lomitapide[2] Lomitapide ,
Lomitapide mesylate 💬 		[1] MTTP 💬 [1] Fat digestion and absorption 💬[1] 79 💬
179Lovastatin[1] Lovastatin[1] Lovastatin 💬 [1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[11] 6, 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
180MBX-8025----[3] 79, 93, 94 💬
181MBX-8025 50 mg (Dose Escalation Period 1)----[1] 79 💬
182MBX-8025 50 mg or 100 mg (Dose Escalation Period 2)----[1] 79 💬
183MBX-8025 50 mg, 100 mg or 200 mg (Dose Escalation Period 3)----[1] 79 💬
184MGL-3196----[1] 79 💬
185MGL-3196 (resmetirom)[1] Resmetirom[1] Resmetirom 💬 [1] THRB 💬 [3] Hormone signaling, Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬[1] 79 💬
186Mipomersen[1] Mipomersen[1] Mipomersen sodium 💬 [1] APOB 💬 [4] Cholesterol metabolism, Fat digestion and absorption, Lipid and atherosclerosis, Vitamin digestion and absorption 💬[1] 79 💬
187Mipomersen Sodium[1] Mipomersen[1] Mipomersen sodium 💬 [1] APOB 💬 [4] Cholesterol metabolism, Fat digestion and absorption, Lipid and atherosclerosis, Vitamin digestion and absorption 💬[1] 79 💬
188Mipomersen sodium 200 mg[1] Mipomersen[1] Mipomersen sodium 💬 [1] APOB 💬 [4] Cholesterol metabolism, Fat digestion and absorption, Lipid and atherosclerosis, Vitamin digestion and absorption 💬[1] 79 💬
189Mipomersen sodium 70 mg[1] Mipomersen[1] Mipomersen sodium 💬 [1] APOB 💬 [4] Cholesterol metabolism, Fat digestion and absorption, Lipid and atherosclerosis, Vitamin digestion and absorption 💬[1] 79 💬
190MK-0524 or L-000888839-000E----[1] 79 💬
191MK-0524A----[1] 79 💬
192MK-0524A (ER-Niacin/MK-0524) 1g/20mg or MK-0524A[1] Niacin[1] Niacin 💬 --[1] 79 💬
193MK-0524A (ER-Niacin/MK-0524) 1g/20mg Tablets or MK-0524A[1] Niacin[1] Niacin 💬 --[1] 79 💬
194MK-0616----[1] 79 💬
195MK-0859----[1] 79 💬
196Monotherapy ezetimibe[1] Ezetimibe[1] Ezetimibe 💬 [1] NPC1L1 💬 [1] Fat digestion and absorption 💬[1] 79 💬
197Monotherapy obicetrapib[1] Obicetrapib[1] Obicetrapib 💬 [1] CETP 💬 [1] Cholesterol metabolism 💬[1] 79 💬
198NGGT006----[1] 79 💬
199Niacin[1] Niacin[1] Niacin 💬 --[4] 6, 46, 79, 265 💬
200Nicotinic acid----[1] 79 💬
201Nicotinic acid/laropiprant[2] Laropiprant,
Niacin		[2] Niacin ,
Laropiprant 💬 		[1] PTGDR 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 79 💬
202Nilemdo----[1] 79 💬
203Nilemdo Product Name: bempedoic acidPharmaceutical Form: TabletINN or Proposed INN: Bempedoic acidCAS Number: 738606-46-7 Current Sponsor code: ETC-1002----[1] 79 💬
204NK 104----[1] 79 💬
205Normal Saline----[20] 6, 13, 17, 22, 36, 46, 49, 60, 70, 71, 79, 94, 96, 97, 210, 211, 226, 276, 296, 299 💬
206OBICETRAPIB[1] Obicetrapib[1] Obicetrapib 💬 [1] CETP 💬 [1] Cholesterol metabolism 💬[1] 79 💬
207Omega-3----[3] 46, 49, 79 💬
208Omega-3 fatty acids[1] Omega-3 fatty acids---[4] 13, 49, 79, 223 💬
209Ongericimab[1] Ongericimab---[1] 79 💬
210Other: Cascade----[1] 79 💬
211Other: Cascade Screening----[1] 79 💬
212Other: Cascade testing----[1] 79 💬
213Other: Consultation with a cardiologist-lipidologist (correction of therapy, lifestyle, diet)----[1] 79 💬
214Other: Historical data of lipid-lowering drug administration----[1] 79 💬
215Other: Historical data of plasma lipids, xanthoma changes----[1] 79 💬
216Other: Inclisiran[1] Inclisiran[2] Inclisiran ,
Inclisiran sodium 💬 		[1] PCSK9 💬 [1] Cholesterol metabolism 💬[1] 79 💬
217Other: low satured diet----[1] 79 💬
218Other: Standard of Care----[11] 13, 49, 57, 64, 79, 85, 95, 96, 97, 245, 246 💬
219Other: Visit 1----[1] 79 💬
220Other: Visit 2----[1] 79 💬
221Other: Visit 3----[1] 79 💬
222Other: Visit 4----[1] 79 💬
223Pactimibe[1] Pactimibe---[1] 79 💬
224Pactimibe sulfate[1] Pactimibe---[1] 79 💬
225PCSK9 Inhibitor [EPC]----[1] 79 💬
226PF-04950615----[1] 79 💬
227Phytosterol----[1] 79 💬
228Pitavastatin[1] Pitavastatin[2] Pitavastatin calcium ,
Pitavastatin magnesium 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[4] 49, 71, 79, 90 💬
229PITAVASTATIN CALCIUM[2] Calcium,
Pitavastatin		[2] Pitavastatin calcium ,
Pitavastatin magnesium 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[1] 79 💬
230Praluent----[1] 79 💬
231Praluent (Alirocumab)[1] Alirocumab[1] Alirocumab 💬 [1] PCSK9 💬 [1] Cholesterol metabolism 💬[1] 79 💬
232Pravastatin[1] Pravastatin[2] Pravastatin sodium ,
Pravastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[11] 13, 46, 49, 67, 79, 96, 164, 210, 222, 265, 333 💬
233Prednisone[1] Prednisone[1] Prednisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[58] 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 127, 145, 162, 164, 205, 222, 223, 224, 228, 251, 269, 283, 284, 285, 288, 299, 300, 303, 307, 331 💬
234Prevenar13----[3] 19, 79, 265 💬
235Probucol[1] Probucol[1] Probucol 💬 --[4] 21, 66, 79, 223 💬
236Protein convertase subtilisin/kexin type 9 inhibitor----[1] 79 💬
237PUFA muffin----[1] 79 💬
238QLC7401----[1] 79 💬
239QLC7401 Injection----[1] 79 💬
240R727----[1] 79 💬
241Rapeseed oil----[1] 79 💬
242Recombinant Human Apolipoprotein----[1] 79 💬
243Recombinant Human Apolipoprotein A-I----[1] 79 💬
244Recombinant Human Apolipoprotein A-I/Phospholipids Complex----[1] 79 💬
245Recombinant human apolipoprotein a1----[1] 79 💬
246REGN 727----[1] 79 💬
247REGN1500----[1] 79 💬
248REGN1500 250 mg SC/15 mg/kg IV/450 mg SC----[1] 79 💬
249REGN727----[1] 79 💬
250REGN727 (SAR236553)----[1] 79 💬
251REGN727/SAR236553----[1] 79 💬
252Repatha (evolocumab)[1] Evolocumab[1] Evolocumab 💬 [1] PCSK9 💬 [1] Cholesterol metabolism 💬[1] 79 💬
253Repatha 140 mg Solution for Injection in Pre-filled Pen----[1] 79 💬
254Repatha 140 mg soluzione per iniezione in penna preriempita.----[1] 79 💬
255Repatha 420 mg solution for injection in cartridge----[1] 79 💬
256Repatha 420 mg soluzione per iniezione in cartuccia----[1] 79 💬
257Resmetirom[1] Resmetirom[1] Resmetirom 💬 [1] THRB 💬 [3] Hormone signaling, Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬[1] 79 💬
258RN316----[1] 79 💬
259RN316)----[1] 79 💬
260Rosuvastatin[1] Rosuvastatin[2] Rosuvastatin calcium ,
Rosuvastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[16] 6, 18, 46, 49, 51, 56, 57, 62, 65, 67, 79, 94, 96, 97, 271, 299 💬
261Rosuvastatin 20mg[1] Rosuvastatin[2] Rosuvastatin calcium ,
Rosuvastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[1] 79 💬
262ROSUVASTATIN CALCIUM[2] Calcium,
Rosuvastatin		[2] Rosuvastatin calcium ,
Rosuvastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[4] 49, 79, 97, 299 💬
263Saline 0.9%----[1] 79 💬
264Salivary sample----[1] 79 💬
265SAR236553----[1] 79 💬
266SAR236553 (REGN727)----[1] 79 💬
267SAR236553/REGN727----[1] 79 💬
268SFA muffin----[1] 79 💬
269Sfingomielina----[1] 79 💬
270SHR-1209----[1] 79 💬
271SHR-1918----[1] 79 💬
272Simvastatin[1] Simvastatin[1] Simvastatin 💬 [1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[22] 6, 13, 15, 34, 46, 49, 51, 57, 66, 79, 86, 89, 94, 158, 160, 162, 195, 223, 265, 298, 299, 310 💬
273Single intravenous (IV) dose of human Low Density Lipoprotein Receptor (LDLR) Gene Therapy----[1] 79 💬
274SINVACOR*10MG 20 CPR RIV.----[1] 79 💬
275SINVACOR*20MG 10 CPR RIV.----[1] 79 💬
276SINVACOR*40MG 10 CPR RIV.----[1] 79 💬
277Sortis 10 mg Filmtabletten----[1] 79 💬
278Sortis 20 mg Filmtabletten----[1] 79 💬
279Sortis 40 mg Filmtabletten----[1] 79 💬
280Soy protein diet----[1] 79 💬
281SPC5001----[1] 79 💬
282Sphingomyelin----[1] 79 💬
283Standard lipid lowering therapy----[1] 79 💬
284Standard of Care----[18] 6, 13, 49, 51, 57, 58, 63, 64, 79, 84, 96, 97, 113, 171, 223, 228, 240, 291 💬
285Statins----[2] 46, 79 💬
286Statins and Ezetimibe[1] Ezetimibe[1] Ezetimibe 💬 [1] NPC1L1 💬 [1] Fat digestion and absorption 💬[1] 79 💬
287Statins and/or Ezetimibe[1] Ezetimibe[1] Ezetimibe 💬 [1] NPC1L1 💬 [1] Fat digestion and absorption 💬[1] 79 💬
288Sterile Normal Saline (0.9% NaCl)----[4] 62, 79, 234, 254 💬
289Sunflower Oil[1] Sunflower oil[1] Sunflower oil 💬 --[4] 13, 46, 79, 299 💬
290SYH2053 Injection----[1] 79 💬
291SYH2070 injection dose1----[1] 79 💬
292SYH2070 injection dose2----[1] 79 💬
293TA-8995----[1] 79 💬
294TAK-475[1] TAK-475[1] Lapaquistat acetate 💬 [1] FDFT1 💬 [1] Steroid biosynthesis 💬[1] 79 💬
295Torcetrapib[1] Torcetrapib[1] Torcetrapib 💬 [1] CETP 💬 [1] Cholesterol metabolism 💬[1] 79 💬
296Torcetrapib (CP-529,414)/Atorvastatin[2] Atorvastatin,
Torcetrapib		[3] Atorvastatin calcium ,
Torcetrapib ,
Atorvastatin 💬 		[2] CETP,
HMGCR 💬 		[4] AMPK signaling pathway, Bile secretion, Cholesterol metabolism, Terpenoid backbone biosynthesis 💬[1] 79 💬
297Torcetrapib/atorvastatin[2] Atorvastatin,
Torcetrapib		[3] Atorvastatin calcium ,
Torcetrapib ,
Atorvastatin 💬 		[2] CETP,
HMGCR 💬 		[4] AMPK signaling pathway, Bile secretion, Cholesterol metabolism, Terpenoid backbone biosynthesis 💬[1] 79 💬
298Tredaptive----[1] 79 💬
299VERVE-101----[1] 79 💬
300VERVE-102----[1] 79 💬
301VSA003----[1] 79 💬
302WelChol----[1] 79 💬
303YOLT-101----[1] 79 💬
304Zarator----[1] 79 💬
305ZD4522----[1] 79 💬
306Zocor----[1] 79 💬
307Zocor 10 mg----[1] 79 💬
308Zocor 20mg----[1] 79 💬
309Zocor 40mg----[1] 79 💬
310Zodasiran[1] Zodasiran---[1] 79 💬
311Zodasiran Injection[1] Zodasiran---[1] 79 💬