Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1AAV directed hldlr gene therapy----[1] 79 💬
2AAV8.TBG.hldlr----[1] 79 💬
3AEGR-733----[1] 79 💬
4AK102----[1] 79 💬
5Akcea-angptl3-LRX----[2] 79, 265 💬
6Alirocumab[1] Alirocumab[1] Alirocumab 💬 [1] PCSK9 💬 [1] Cholesterol metabolism 💬[1] 79 💬
7ALN-60212----[1] 79 💬
8ALN-pcssc[1] Inclisiran[2] Inclisiran ,
Inclisiran sodium 💬 		[1] PCSK9 💬 [1] Cholesterol metabolism 💬[1] 79 💬
9AMG 145----[1] 79 💬
10AMG145----[1] 79 💬
11Anacetrapib[1] Anacetrapib[1] Anacetrapib 💬 [1] CETP 💬 [1] Cholesterol metabolism 💬[1] 79 💬
12ARO-ANG 3 injection----[1] 79 💬
13Atorvastatin[1] Atorvastatin[2] Atorvastatin calcium ,
Atorvastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[17] 13, 22, 46, 49, 51, 58, 79, 84, 88, 93, 96, 97, 160, 225, 271, 297, 299 💬
14AZD4522----[1] 79 💬
15BMS356384----[1] 79 💬
16CER-001[1] CER-001---[1] 79 💬
17Cholestagel[1] Colesevelam[2] Colesevelam hydrochloride ,
Colesevelam 💬 		--[2] 79, 96 💬
18Cholestyramine[1] Cholestyramine[1] Cholestyramine resin 💬 --[2] 13, 79 💬
19Colesevelam hydrochloride[1] Colesevelam[2] Colesevelam hydrochloride ,
Colesevelam 💬 		--[1] 79 💬
20Colesevelam hydrochloride FILM-coated tablets[1] Colesevelam[2] Colesevelam hydrochloride ,
Colesevelam 💬 		--[1] 79 💬
21Crestor[1] Rosuvastatin[2] Rosuvastatin calcium ,
Rosuvastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[3] 49, 79, 299 💬
22Crestor FILM-coated tablet[1] Rosuvastatin[2] Rosuvastatin calcium ,
Rosuvastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[1] 79 💬
23Crestor tablets (calcium rosuvastatin) FILM-coated tablets[1] Rosuvastatin[2] Rosuvastatin calcium ,
Rosuvastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[1] 79 💬
24Dextran sulfate adsorption[1] Dextran[5] Dextran 1 ,
Dextran sulfate sodium ,
Dextran 40 ,
Dextran 70 ,
Dextran 75 💬 		[2] LIPC,
LPL 💬 		[4] Alzheimer disease, Cholesterol metabolism, Glycerolipid metabolism, PPAR signaling pathway 💬[1] 79 💬
25Dppg----[1] 79 💬
26Eprotirome[1] Eprotirome---[1] 79 💬
27Evinacumab[1] Evinacumab[1] Evinacumab 💬 [1] ANGPTL3 💬 [1] Cholesterol metabolism 💬[1] 79 💬
28Evolocumab[1] Evolocumab[1] Evolocumab 💬 [1] PCSK9 💬 [1] Cholesterol metabolism 💬[2] 79, 222 💬
29Ezetimibe[1] Ezetimibe[1] Ezetimibe 💬 [1] NPC1L1 💬 [1] Fat digestion and absorption 💬[4] 79, 93, 149, 260 💬
30Fenofibrate[1] Fenofibrate[1] Fenofibrate 💬 [1] NR1C1 💬 [10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[6] 8, 79, 93, 94, 97, 265 💬
31Fish OIL capsule[1] Fish oil---[1] 79 💬
32Fluvastatin[1] Fluvastatin[2] Fluvastatin sodium ,
Fluvastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[2] 79, 222 💬
33Gemcabene[1] Gemcabene---[1] 79 💬
34Gene analysis----[1] 79 💬
35Glycerol[1] Glycerin[1] Glycerin 💬 --[1] 79 💬
36Heparin-induced extracorporeal LDL precipitation[1] Heparin[2] Heparin sodium ,
Heparin calcium 💬 		[1] SERPINC1 💬 [1] Complement and coagulation cascades 💬[1] 79 💬
37Historical data OF lipid-lowering drug administration----[1] 79 💬
38Historical data OF plasma lipids, xanthoma changes----[1] 79 💬
39HMG coenzyme reductase----[1] 79 💬
40IBI306----[1] 79 💬
41Implitapide[1] Implitapide---[1] 79 💬
42Inclisiran[1] Inclisiran[2] Inclisiran ,
Inclisiran sodium 💬 		[1] PCSK9 💬 [1] Cholesterol metabolism 💬[1] 79 💬
43Inclisiran sodium[1] Inclisiran[2] Inclisiran ,
Inclisiran sodium 💬 		[1] PCSK9 💬 [1] Cholesterol metabolism 💬[1] 79 💬
44Inclisiran sodium FOR injection[1] Inclisiran[2] Inclisiran ,
Inclisiran sodium 💬 		[1] PCSK9 💬 [1] Cholesterol metabolism 💬[1] 79 💬
45Isis 301012----[1] 79 💬
46Isis 301012 phosphorothioate oligonucleotide----[1] 79 💬
47Isis 703802----[1] 79 💬
48JS002----[1] 79 💬
49KB2115----[1] 79 💬
50KJX839----[1] 79 💬
51Lapaquistat acetate and current lipid-lowering treatment[1] Lapaquistat---[1] 79 💬
52Leqvio 284 MG solution FOR injection IN PRE-filled syringe[1] Inclisiran[2] Inclisiran ,
Inclisiran sodium 💬 		[1] PCSK9 💬 [1] Cholesterol metabolism 💬[1] 79 💬
53Lerodalcibep[1] Lerodalcibep[1] Lerodalcibep 💬 [1] PCSK9 💬 [1] Cholesterol metabolism 💬[1] 79 💬
54LIB003----[1] 79 💬
55Lojuxta 10 MG hard capsules[1] Lomitapide[2] Lomitapide ,
Lomitapide mesylate 💬 		[1] MTTP 💬 [1] Fat digestion and absorption 💬[1] 79 💬
56Lojuxta 20 MG hard capsules[1] Lomitapide[2] Lomitapide ,
Lomitapide mesylate 💬 		[1] MTTP 💬 [1] Fat digestion and absorption 💬[1] 79 💬
57Lojuxta 5 MG hard capsules[1] Lomitapide[2] Lomitapide ,
Lomitapide mesylate 💬 		[1] MTTP 💬 [1] Fat digestion and absorption 💬[1] 79 💬
58Lomitapide[1] Lomitapide[2] Lomitapide ,
Lomitapide mesylate 💬 		[1] MTTP 💬 [1] Fat digestion and absorption 💬[1] 79 💬
59Lomitapide 2MG hard capsules[1] Lomitapide[2] Lomitapide ,
Lomitapide mesylate 💬 		[1] MTTP 💬 [1] Fat digestion and absorption 💬[1] 79 💬
60Lovastatin[1] Lovastatin[1] Lovastatin 💬 [1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[11] 6, 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
61Maintenance OF specific diet----[1] 79 💬
62MBX-8025----[3] 79, 93, 94 💬
63Mipomersen[1] Mipomersen[1] Mipomersen sodium 💬 [1] APOB 💬 [4] Cholesterol metabolism, Fat digestion and absorption, Lipid and atherosclerosis, Vitamin digestion and absorption 💬[1] 79 💬
64MK-0859----[1] 79 💬
65NGGT006----[1] 79 💬
66Nicotinic acid[1] Niacin[1] Niacin 💬 --[1] 79 💬
67Omega-3 fatty acids[1] Omega-3 fatty acids---[2] 13, 79 💬
68Praluent[1] Alirocumab[1] Alirocumab 💬 [1] PCSK9 💬 [1] Cholesterol metabolism 💬[1] 79 💬
69Pravastatin[1] Pravastatin[2] Pravastatin sodium ,
Pravastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[10] 13, 46, 49, 67, 79, 96, 164, 210, 265, 333 💬
70Prednisone[1] Prednisone[1] Prednisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[54] 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 145, 162, 164, 205, 222, 224, 228, 251, 269, 283, 285, 288, 299, 300, 303, 307, 331 💬
71Probucol[1] Probucol[1] Probucol 💬 --[3] 21, 66, 79 💬
72R727----[1] 79 💬
73Rapeseed OIL----[1] 79 💬
74Recombinant human apolipoprotein----[1] 79 💬
75Recombinant human apolipoprotein A-I/phospholipids complex----[1] 79 💬
76Recombinant human apolipoprotein A1----[1] 79 💬
77REGN1500----[1] 79 💬
78REGN1500 250 MG SC/15 MG/KG IV/450 MG SC----[1] 79 💬
79Repatha 140 MG solution FOR injection IN PRE-filled PEN[1] Evolocumab[1] Evolocumab 💬 [1] PCSK9 💬 [1] Cholesterol metabolism 💬[1] 79 💬
80Repatha 420 MG solution FOR injection IN cartridge[1] Evolocumab[1] Evolocumab 💬 [1] PCSK9 💬 [1] Cholesterol metabolism 💬[1] 79 💬
81Repatha 420 MG soluzione PER iniezione IN cartuccia[1] Evolocumab[1] Evolocumab 💬 [1] PCSK9 💬 [1] Cholesterol metabolism 💬[1] 79 💬
82Rosuvastatin[1] Rosuvastatin[2] Rosuvastatin calcium ,
Rosuvastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[9] 6, 18, 46, 49, 51, 79, 94, 96, 271 💬
83Rosuvastatin 20MG[1] Rosuvastatin[2] Rosuvastatin calcium ,
Rosuvastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[1] 79 💬
84Rosuvastatin calcium[1] Rosuvastatin[2] Rosuvastatin calcium ,
Rosuvastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[4] 49, 79, 97, 299 💬
85SAR236553----[1] 79 💬
86Sfingomielina----[1] 79 💬
87SHR-1209----[1] 79 💬
88SHR-1918----[1] 79 💬
89Simvastatin[1] Simvastatin[1] Simvastatin 💬 [1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[19] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 158, 160, 195, 265, 288, 298, 299, 310 💬
90Single intravenous (IV) dose OF human LOW density lipoprotein receptor (ldlr) gene therapy----[1] 79 💬
91SOY protein diet----[1] 79 💬
92Sphingomyelin----[1] 79 💬
93Statins----[2] 46, 79 💬
94TAK-475[1] TAK-475---[1] 79 💬
95Torcetrapib/atorvastatin[1] Torcetrapib[1] Torcetrapib 💬 [1] CETP 💬 [1] Cholesterol metabolism 💬[1] 79 💬
96VSA003----[1] 79 💬
97Whole genome sequencing----[5] 2, 6, 79, 127, 172 💬
98ZD4522----[1] 79 💬