Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Alirocumab 💬[1] Alirocumab[1] ALIROCUMAB[1] PCSK9 💬 [1] Cholesterol metabolism 💬[1] 79 💬
2 Amlodipine 💬[1] Amlodipine[1] AMLODIPINE[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 51, 67, 79, 113, 222, 298 💬
3 Amlodipine benzoate 💬[1] Amlodipine[1] Amlodipine[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 51, 67, 79, 113, 222, 298 💬
4 Amlodipine besylate 💬[1] Amlodipine[1] Amlodipine[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 51, 67, 79, 113, 222, 298 💬
5 Amlodipine maleate 💬[1] Amlodipine[1] AMLODIPINE[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 51, 67, 79, 113, 222, 298 💬
6 Anacetrapib 💬[1] Anacetrapib[1] ANACETRAPIB[1] CETP 💬 [1] Cholesterol metabolism 💬[1] 79 💬
7 Atorvastatin 💬[1] Atorvastatin[3] Atorvastatin; Atorvastatin calcium; Atorvastatina[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[21] 13, 22, 46, 49, 51, 58, 63, 67, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
8 Atorvastatin calcium 💬[1] Atorvastatin[3] Atorvastatin; Atorvastatin Calcium; Atorvastatina[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[21] 13, 22, 46, 49, 51, 58, 63, 67, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
9 Bempedoic acid 💬[1] Bempedoic acid[1] Bempedoic acid[1] ACLY 💬 [1] Citrate cycle (TCA cycle) 💬[2] 67, 79 💬
10 Bococizumab 💬[1] Bococizumab[1] Bococizumab[1] PCSK9 💬 [1] Cholesterol metabolism 💬[1] 79 💬
11 Cholesterol 💬[1] Cholesterol[1] Cholesterol--[10] 8, 19, 71, 79, 90, 160, 222, 259, 261, 310 💬
12 Cholestyramine resin 💬[1] Cholestyramine[2] Cholestyramine; COLESTIRAMINA--[2] 13, 79 💬
13 Colesevelam 💬[1] Colesevelam[2] Colesevelam; Colesevelam hydrochloride--[3] 79, 96, 260 💬
14 Colesevelam hydrochloride 💬[1] Colesevelam[2] Colesevelam; Colesevelam hydrochloride--[3] 79, 96, 260 💬
15 Dextran 1 💬[1] Dextran[2] Dextran; DEXTRAN SULFATE SODIUM--[5] 2, 62, 79, 96, 97 💬
16 Dextran 40 💬[1] Dextran[2] Dextran; DEXTRAN SULFATE SODIUM--[5] 2, 62, 79, 96, 97 💬
17 Dextran 70 💬[1] Dextran[2] Dextran; DEXTRAN SULFATE SODIUM--[5] 2, 62, 79, 96, 97 💬
18 Dextran 75 💬[1] Dextran[2] Dextran; DEXTRAN SULFATE SODIUM--[5] 2, 62, 79, 96, 97 💬
19 Dextran sulfate sodium 💬[1] Dextran[2] Dextran; DEXTRAN SULFATE SODIUM[2] LIPC,
LPL 💬 		[4] Alzheimer disease, Cholesterol metabolism, Glycerolipid metabolism, PPAR signaling pathway 💬[5] 2, 62, 79, 96, 97 💬
20 Evinacumab 💬[1] Evinacumab[1] EVINACUMAB[1] ANGPTL3 💬 [1] Cholesterol metabolism 💬[1] 79 💬
21 Evolocumab 💬[1] Evolocumab[1] EVOLOCUMAB[1] PCSK9 💬 [1] Cholesterol metabolism 💬[2] 79, 222 💬
22 Ezetimibe 💬[1] Ezetimibe[1] EZETIMIBE[1] NPC1L1 💬 [1] Fat digestion and absorption 💬[5] 49, 79, 93, 149, 260 💬
23 Fenofibrate 💬[1] Fenofibrate[1] Fenofibrate[1] PPARA 💬 [10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[6] 8, 79, 93, 94, 97, 265 💬
24 Fluvastatin 💬[1] Fluvastatin[1] Fluvastatin[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[4] 48, 79, 218, 222 💬
25 Fluvastatin sodium 💬[1] Fluvastatin[1] Fluvastatin[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[4] 48, 79, 218, 222 💬
26 Heparin calcium 💬[1] Heparin[2] Heparin; HEPARIN SODIUM[1] SERPINC1 💬 [1] Complement and coagulation cascades 💬[15] 47, 48, 60, 65, 70, 79, 84, 107, 224, 226, 280, 299, 316, 317, 344 💬
27 Heparin sodium 💬[1] Heparin[2] Heparin; HEPARIN SODIUM[1] SERPINC1 💬 [1] Complement and coagulation cascades 💬[15] 47, 48, 60, 65, 70, 79, 84, 107, 224, 226, 280, 299, 316, 317, 344 💬
28 Inclisiran 💬[1] Inclisiran[3] ALN-PCSSC; INCLISIRAN; Inclisiran Sodium[1] PCSK9 💬 [1] Cholesterol metabolism 💬[1] 79 💬
29 Inclisiran sodium 💬[1] Inclisiran[3] ALN-PCSSC; INCLISIRAN; Inclisiran Sodium[1] PCSK9 💬 [1] Cholesterol metabolism 💬[1] 79 💬
30 Lapaquistat acetate 💬[1] TAK-475[1] TAK-475[1] FDFT1 💬 [1] Steroid biosynthesis 💬[1] 79 💬
31 Laropiprant 💬[1] Laropiprant[1] Laropiprant[1] PTGDR 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 79 💬
32 Lerodalcibep 💬[1] Lerodalcibep[1] Lerodalcibep[1] PCSK9 💬 [1] Cholesterol metabolism 💬[1] 79 💬
33 Lomitapide 💬[1] Lomitapide[1] LOMITAPIDE[1] MTTP 💬 [1] Fat digestion and absorption 💬[1] 79 💬
34 Lomitapide mesylate 💬[1] Lomitapide[1] LOMITAPIDE[1] MTTP 💬 [1] Fat digestion and absorption 💬[1] 79 💬
35 Lovastatin 💬[1] Lovastatin[1] LOVASTATIN[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[11] 6, 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
36 Mipomersen sodium 💬[1] Mipomersen[2] Mipomersen; Mipomersen Sodium[1] APOB 💬 [4] Cholesterol metabolism, Fat digestion and absorption, Lipid and atherosclerosis, Vitamin digestion and absorption 💬[1] 79 💬
37 Niacin 💬[1] Niacin[2] Niacin; Nicotinic acid--[4] 6, 46, 79, 265 💬
38 Obicetrapib 💬[1] Obicetrapib[1] OBICETRAPIB[1] CETP 💬 [1] Cholesterol metabolism 💬[1] 79 💬
39 Pitavastatin calcium 💬[1] Pitavastatin[2] Pitavastatin; PITAVASTATIN CALCIUM[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[4] 49, 71, 79, 90 💬
40 Pitavastatin magnesium 💬[1] Pitavastatin[2] Pitavastatin; PITAVASTATIN CALCIUM[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[4] 49, 71, 79, 90 💬
41 Pravastatin 💬[1] Pravastatin[2] Pravastatin; Pravastatin sodium[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[11] 13, 46, 49, 67, 79, 96, 164, 210, 222, 265, 333 💬
42 Pravastatin sodium 💬[1] Pravastatin[2] Pravastatin; Pravastatin sodium[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[11] 13, 46, 49, 67, 79, 96, 164, 210, 222, 265, 333 💬
43 Prednisone 💬[1] Prednisone[2] PREDNISONA; Prednisone[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[58] 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 127, 145, 162, 164, 205, 222, 223, 224, 228, 251, 269, 283, 284, 285, 288, 299, 300, 303, 307, 331 💬
44 Probucol 💬[1] Probucol[1] Probucol--[4] 21, 66, 79, 223 💬
45 Resmetirom 💬[1] Resmetirom[1] Resmetirom[1] THRB 💬 [3] Hormone signaling, Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬[1] 79 💬
46 Rosuvastatin 💬[1] Rosuvastatin[2] Rosuvastatin; Rosuvastatin calcium[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[16] 6, 18, 46, 49, 51, 56, 57, 62, 65, 67, 79, 94, 96, 97, 271, 299 💬
47 Rosuvastatin calcium 💬[1] Rosuvastatin[2] Rosuvastatin; ROSUVASTATIN CALCIUM[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[16] 6, 18, 46, 49, 51, 56, 57, 62, 65, 67, 79, 94, 96, 97, 271, 299 💬
48 Simvastatin 💬[1] Simvastatin[2] Simvastatin; Simvastatine[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[22] 6, 13, 15, 34, 46, 49, 51, 57, 66, 79, 86, 89, 94, 158, 160, 162, 195, 223, 265, 298, 299, 310 💬
49 Sunflower oil 💬[1] Sunflower oil[1] Sunflower Oil--[4] 13, 46, 79, 299 💬
50 Torcetrapib 💬[1] Torcetrapib[1] Torcetrapib[1] CETP 💬 [1] Cholesterol metabolism 💬[1] 79 💬