Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Acetate [1] Acetate---[52] 1, 2, 6, 10, 11, 13, 22, 35, 40, 46, 49, 51, 60, 63, 64, 65, 66, 67, 70, 71, 73, 75, 76, 77, 78, 79, 81, 83, 85, 86, 88, 89, 90, 96, 97, 113, 145, 156, 158, 162, 171, 206, 222, 223, 224, 225, 227, 235, 251, 265, 298, 299 💬
2 Alirocumab [1] ALIROCUMAB[1] Alirocumab 💬 [1] PCSK9 💬 [1] Cholesterol metabolism 💬[1] 79 💬
3 Amlodipine [1] AMLODIPINE[4] Amlodipine besylate ,
Amlodipine maleate ,
Amlodipine ,
Amlodipine benzoate 💬 		[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 51, 67, 79, 113, 222, 298 💬
4 Anacetrapib [1] ANACETRAPIB[1] Anacetrapib 💬 [1] CETP 💬 [1] Cholesterol metabolism 💬[1] 79 💬
5 Atorvastatin [3] Atorvastatin; Atorvastatin Calcium; Atorvastatina[2] Atorvastatin calcium ,
Atorvastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[21] 13, 22, 46, 49, 51, 58, 63, 67, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
6 Bempedoic acid [1] Bempedoic acid[1] Bempedoic acid 💬 [1] ACLY 💬 [1] Citrate cycle (TCA cycle) 💬[2] 67, 79 💬
7 Bococizumab [1] Bococizumab[1] Bococizumab 💬 [1] PCSK9 💬 [1] Cholesterol metabolism 💬[1] 79 💬
8 Calcium [1] Calcium---[39] 2, 3, 6, 13, 15, 19, 46, 48, 49, 51, 53, 56, 62, 67, 68, 71, 74, 75, 79, 84, 90, 93, 94, 95, 96, 97, 156, 186, 214, 215, 222, 224, 235, 256, 265, 271, 274, 298, 299 💬
9 CER-001 [1] CER-001---[1] 79 💬
10 Cholesterol [1] Cholesterol[1] Cholesterol 💬 --[10] 8, 19, 71, 79, 90, 160, 222, 259, 261, 310 💬
11 Cholestyramine [2] Cholestyramine; COLESTIRAMINA[1] Cholestyramine resin 💬 --[2] 13, 79 💬
12 Colesevelam [2] Colesevelam; Colesevelam hydrochloride[2] Colesevelam hydrochloride ,
Colesevelam 💬 		--[3] 79, 96, 260 💬
13 Dextran [2] Dextran; DEXTRAN SULFATE SODIUM[5] Dextran 1 ,
Dextran sulfate sodium ,
Dextran 40 ,
Dextran 70 ,
Dextran 75 💬 		[2] LIPC,
LPL 💬 		[4] Alzheimer disease, Cholesterol metabolism, Glycerolipid metabolism, PPAR signaling pathway 💬[5] 2, 62, 79, 96, 97 💬
14 Eprotirome [1] Eprotirome---[1] 79 💬
15 Evinacumab [1] EVINACUMAB[1] Evinacumab 💬 [1] ANGPTL3 💬 [1] Cholesterol metabolism 💬[1] 79 💬
16 Evolocumab [1] EVOLOCUMAB[1] Evolocumab 💬 [1] PCSK9 💬 [1] Cholesterol metabolism 💬[2] 79, 222 💬
17 Ezetimibe [1] Ezetimibe[1] Ezetimibe 💬 [1] NPC1L1 💬 [1] Fat digestion and absorption 💬[5] 49, 79, 93, 149, 260 💬
18 Fenofibrate [1] Fenofibrate[1] Fenofibrate 💬 [1] PPARA 💬 [10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[6] 8, 79, 93, 94, 97, 265 💬
19 Fish oil [1] Fish Oil---[10] 13, 46, 49, 50, 66, 79, 96, 260, 294, 299 💬
20 Fluvastatin [1] Fluvastatin[2] Fluvastatin sodium ,
Fluvastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[4] 48, 79, 218, 222 💬
21 Gemcabene [1] Gemcabene---[2] 79, 265 💬
22 Gold [1] Gold---[71] 2, 5, 6, 11, 13, 17, 19, 21, 22, 28, 34, 35, 46, 49, 50, 53, 54, 56, 57, 58, 60, 63, 64, 65, 66, 68, 71, 75, 76, 77, 79, 84, 85, 86, 88, 91, 93, 95, 96, 97, 98, 107, 113, 127, 137, 158, 162, 167, 171, 193, 206, 215, 218, 222, 223, 224, 226, 227, 228, 230, 235, 271, 291, 294, 296, 298, 299, 310, 318, 331, 340 💬
23 Heparin [2] Heparin; HEPARIN SODIUM[2] Heparin sodium ,
Heparin calcium 💬 		[1] SERPINC1 💬 [1] Complement and coagulation cascades 💬[15] 47, 48, 60, 65, 70, 79, 84, 107, 224, 226, 280, 299, 316, 317, 344 💬
24 Implitapide [1] Implitapide---[1] 79 💬
25 Inclisiran [3] ALN-PCSSC; INCLISIRAN; Inclisiran Sodium[2] Inclisiran ,
Inclisiran sodium 💬 		[1] PCSK9 💬 [1] Cholesterol metabolism 💬[1] 79 💬
26 Krill oil [1] Krill oil---[1] 79 💬
27 Lactobacillus paracasei [1] Lactobacillus paracasei---[1] 79 💬
28 Lapaquistat [1] Lapaquistat---[1] 79 💬
29 Laropiprant [1] Laropiprant[1] Laropiprant 💬 [1] PTGDR 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 79 💬
30 Lerodalcibep [1] Lerodalcibep[1] Lerodalcibep 💬 [1] PCSK9 💬 [1] Cholesterol metabolism 💬[1] 79 💬
31 Lomitapide [1] LOMITAPIDE[2] Lomitapide ,
Lomitapide mesylate 💬 		[1] MTTP 💬 [1] Fat digestion and absorption 💬[1] 79 💬
32 Lovastatin [1] Lovastatin[1] Lovastatin 💬 [1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[11] 6, 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
33 Mipomersen [2] Mipomersen; Mipomersen Sodium[1] Mipomersen sodium 💬 [1] APOB 💬 [4] Cholesterol metabolism, Fat digestion and absorption, Lipid and atherosclerosis, Vitamin digestion and absorption 💬[1] 79 💬
34 Niacin [2] Niacin; Nicotinic acid[1] Niacin 💬 --[4] 6, 46, 79, 265 💬
35 Obicetrapib [1] OBICETRAPIB[1] Obicetrapib 💬 [1] CETP 💬 [1] Cholesterol metabolism 💬[1] 79 💬
36 Omega-3 fatty acids [3] Omega 3 fatty acids; Omega-3; Omega-3 fatty acids---[4] 13, 49, 79, 223 💬
37 Ongericimab [1] Ongericimab---[1] 79 💬
38 Pactimibe [1] Pactimibe---[1] 79 💬
39 Pitavastatin [2] Pitavastatin; PITAVASTATIN CALCIUM[2] Pitavastatin calcium ,
Pitavastatin magnesium 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[4] 49, 71, 79, 90 💬
40 Pravastatin [2] Pravastatin; Pravastatin sodium[2] Pravastatin sodium ,
Pravastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[11] 13, 46, 49, 67, 79, 96, 164, 210, 222, 265, 333 💬
41 Prednisone [2] PREDNISONA; Prednisone[1] Prednisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[58] 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 127, 145, 162, 164, 205, 222, 223, 224, 228, 251, 269, 283, 284, 285, 288, 299, 300, 303, 307, 331 💬
42 Probucol [1] Probucol[1] Probucol 💬 --[4] 21, 66, 79, 223 💬
43 Resmetirom [1] Resmetirom[1] Resmetirom 💬 [1] THRB 💬 [3] Hormone signaling, Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬[1] 79 💬
44 Rosuvastatin [2] Rosuvastatin; Rosuvastatin calcium[2] Rosuvastatin calcium ,
Rosuvastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[16] 6, 18, 46, 49, 51, 56, 57, 62, 65, 67, 79, 94, 96, 97, 271, 299 💬
45 Simvastatin [2] Simvastatin; Simvastatine[1] Simvastatin 💬 [1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[22] 6, 13, 15, 34, 46, 49, 51, 57, 66, 79, 86, 89, 94, 158, 160, 162, 195, 223, 265, 298, 299, 310 💬
46 Sunflower oil [1] Sunflower oil[1] Sunflower oil 💬 --[4] 13, 46, 79, 299 💬
47 TAK-475 [1] TAK-475[1] Lapaquistat acetate 💬 [1] FDFT1 💬 [1] Steroid biosynthesis 💬[1] 79 💬
48 Torcetrapib [1] Torcetrapib[1] Torcetrapib 💬 [1] CETP 💬 [1] Cholesterol metabolism 💬[1] 79 💬
49 Zodasiran [2] ARO-ANG3; Zodasiran---[1] 79 💬