Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1 Alirocumab [1] Alirocumab[1] Alirocumab 💬 [1] PCSK9 💬 [1] Cholesterol metabolism 💬[1] 79 💬
2 Anacetrapib [1] Anacetrapib[1] Anacetrapib 💬 [1] CETP 💬 [1] Cholesterol metabolism 💬[1] 79 💬
3 Atorvastatin [2] Atorvastatin; Atorvastatin calcium[2] Atorvastatin calcium ,
Atorvastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[20] 13, 22, 46, 49, 51, 58, 63, 67, 79, 84, 88, 93, 96, 97, 160, 225, 265, 271, 297, 299 💬
4 CER-001 [1] CER-001---[1] 79 💬
5 Cholestyramine [3] Cholestyramine; Colestiramina; Colestyramine[1] Cholestyramine resin 💬 --[3] 13, 79, 254 💬
6 Colesevelam [2] Colesevelam; Colesevelam hydrochloride[2] Colesevelam hydrochloride ,
Colesevelam 💬 		--[2] 79, 96 💬
7 Dextran [2] Dextran; Dextran sulfate sodium[5] Dextran 1 ,
Dextran sulfate sodium ,
Dextran 40 ,
Dextran 70 ,
Dextran 75 💬 		[2] LIPC,
LPL 💬 		[4] Alzheimer disease, Cholesterol metabolism, Glycerolipid metabolism, PPAR signaling pathway 💬[3] 2, 79, 97 💬
8 Eprotirome [1] Eprotirome---[1] 79 💬
9 Evinacumab [1] Evinacumab[1] Evinacumab 💬 [1] ANGPTL3 💬 [1] Cholesterol metabolism 💬[1] 79 💬
10 Evolocumab [1] Evolocumab[1] Evolocumab 💬 [1] PCSK9 💬 [1] Cholesterol metabolism 💬[2] 79, 222 💬
11 Ezetimibe [1] Ezetimibe[1] Ezetimibe 💬 [1] NPC1L1 💬 [1] Fat digestion and absorption 💬[5] 49, 79, 93, 149, 260 💬
12 Fenofibrate [1] Fenofibrate[1] Fenofibrate 💬 [1] NR1C1 💬 [10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[6] 8, 79, 93, 94, 97, 265 💬
13 Fish oil [1] Fish OIL---[6] 13, 46, 49, 79, 96, 299 💬
14 Fluvastatin [1] Fluvastatin[2] Fluvastatin sodium ,
Fluvastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[2] 79, 222 💬
15 Gemcabene [1] Gemcabene---[1] 79 💬
16 Glycerin [1] Glycerol[1] Glycerin 💬 --[10] 6, 7, 13, 21, 79, 265, 302, 316, 317, 344 💬
17 Heparin [2] Heparin; Heparin sodium[2] Heparin sodium ,
Heparin calcium 💬 		[1] SERPINC1 💬 [1] Complement and coagulation cascades 💬[10] 47, 60, 65, 70, 79, 84, 107, 226, 280, 299 💬
18 Implitapide [1] Implitapide---[1] 79 💬
19 Inclisiran [3] ALN-pcssc; Inclisiran; Inclisiran sodium[2] Inclisiran ,
Inclisiran sodium 💬 		[1] PCSK9 💬 [1] Cholesterol metabolism 💬[1] 79 💬
20 Lapaquistat [0] ---[1] 79 💬
21 Lerodalcibep [1] Lerodalcibep[1] Lerodalcibep 💬 [1] PCSK9 💬 [1] Cholesterol metabolism 💬[1] 79 💬
22 Lomitapide [1] Lomitapide[2] Lomitapide ,
Lomitapide mesylate 💬 		[1] MTTP 💬 [1] Fat digestion and absorption 💬[1] 79 💬
23 Lovastatin [1] Lovastatin[1] Lovastatin 💬 [1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[11] 6, 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
24 Mipomersen [1] Mipomersen[1] Mipomersen sodium 💬 [1] APOB 💬 [4] Cholesterol metabolism, Fat digestion and absorption, Lipid and atherosclerosis, Vitamin digestion and absorption 💬[1] 79 💬
25 Niacin [2] Niacin; Nicotinic acid[1] Niacin 💬 --[3] 6, 79, 265 💬
26 Omega-3 fatty acids [5] Omega 3 fatty acids; Omega-3; Omega-3 fatty acid; Omega-3 fatty acids; Omega-3-acid triglycerides---[7] 13, 46, 49, 66, 79, 96, 299 💬
27 Pravastatin [2] Pravastatin; Pravastatin sodium[2] Pravastatin sodium ,
Pravastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[10] 13, 46, 49, 67, 79, 96, 164, 210, 265, 333 💬
28 Prednisone [2] Prednisona; Prednisone[1] Prednisone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[54] 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 145, 162, 164, 205, 222, 224, 228, 251, 269, 283, 285, 288, 299, 300, 303, 307, 331 💬
29 Probucol [1] Probucol[1] Probucol 💬 --[3] 21, 66, 79 💬
30 Rosuvastatin [2] Rosuvastatin; Rosuvastatin calcium[2] Rosuvastatin calcium ,
Rosuvastatin 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[13] 6, 18, 46, 49, 51, 56, 65, 79, 94, 96, 97, 271, 299 💬
31 Simvastatin [2] Simvastatin; Simvastatine[1] Simvastatin 💬 [1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[21] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
32 TAK-475 [1] TAK-475---[1] 79 💬
33 Torcetrapib [0] [1] Torcetrapib 💬 [1] CETP 💬 [1] Cholesterol metabolism 💬[1] 79 💬