Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1(2)-epigallocatechin-3-gallate (EGCG)[1] Epigallocatechin---[1] 8 💬
220 mg BID of PF-02545920----[1] 8 💬
320mg daily citalopram[1] Citalopram[2] Citalopram hydrobromide ,
Citalopram 💬 		[1] SLC6A4 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 8 💬
45-Chloro-1,2-dihydro-N-ethyl-4-hydroxy-1-methyl-2-oxo-N-phenyl-3-quinolinecarboxamide sodium----[1] 8 💬
5[123I]MNI-420----[2] 6, 8 💬
6[14C] LPM3770164----[1] 8 💬
7[18F]-MNI-659----[1] 8 💬
8[18F]FPEB----[3] 6, 8, 206 💬
9[LMI070]----[1] 8 💬
10[PL101]----[1] 8 💬
11[Ro 723-4292/F02]----[1] 8 💬
12[SOM3355]----[1] 8 💬
13[VO659][1] VO659---[2] 8, 18 💬
14[WVE-003][1] WVE-003---[1] 8 💬
15AAVrh10.CAG.hCYP46A1----[1] 8 💬
16ACR16----[1] 8 💬
17ACR16 10 mg----[1] 8 💬
18ACR16 22.5 mg----[1] 8 💬
19ACR16 45 mg----[1] 8 💬
20ACR16 hydrochloride, ASP2314 hydrochloride, FR310826----[1] 8 💬
21ADENO-ASSOCIATED VIRAL VECTOR SEROTYPE RH10 CONTAINING THE HUMAN CHOLESTEROL 24-HYDROXYLASE GENE[1] Cholesterol[1] Cholesterol 💬 --[1] 8 💬
22ADENO-ASSOCIATED VIRUS SEROTYPE 5 ENCODING A MICRORNA TARGETED TO HUMAN HUNTINGTIN GENE----[1] 8 💬
23AFQ056----[3] 6, 8, 206 💬
24ALN-HTT02----[1] 8 💬
25Alprazolam[1] Alprazolam[1] Alprazolam 💬 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[2] 8, 75 💬
26Amantadine[1] Amantadine[2] Amantadine hydrochloride ,
Amantadine 💬 		[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[21] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[5] 2, 6, 8, 13, 127 💬
27AMT-130[1] AMT-130---[1] 8 💬
28Anti-Parkinson medication----[5] 5, 6, 7, 8, 17 💬
29ANX005----[3] 2, 8, 61 💬
30Atomoxetine[1] Atomoxetine[2] Atomoxetine hydrochloride ,
Atomoxetine 💬 		[1] SLC6A2 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle 💬[4] 6, 8, 13, 17 💬
31Autologous Stem Cell----[1] 8 💬
32Benerva----[1] 8 💬
33Bevantolol[1] Bevantolol[1] Bevantolol hydrochloride 💬 [8] ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		[44] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gap junction, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hormone signaling, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Regulation of lipolysis in adipocytes, Renin secretion, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 8 💬
34BEVANTOLOL HYDROCHLORIDE[1] Bevantolol[1] Bevantolol hydrochloride 💬 [8] ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		[44] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gap junction, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hormone signaling, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Regulation of lipolysis in adipocytes, Renin secretion, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 8 💬
35BEVANTOLOLO CLORIDRATO----[1] 8 💬
36BioStamp nPoint device----[1] 8 💬
37BIOTIN[1] Biotin[1] Biotin 💬 --[6] 2, 8, 10, 13, 14, 20 💬
38Biotina[1] Biotin[1] Biotin 💬 --[1] 8 💬
39Blood sample----[33] 2, 3, 6, 8, 10, 13, 14, 19, 34, 46, 48, 49, 51, 53, 61, 63, 65, 66, 67, 77, 79, 84, 88, 96, 97, 107, 113, 127, 195, 206, 235, 274, 299 💬
40BN82451B----[1] 8 💬
41BN8251B----[1] 8 💬
42Brain MRI----[1] 8 💬
43Branaplam[1] Branaplam[1] Branaplam 💬 --[2] 3, 8 💬
44Bupropion[1] Bupropion[3] Bupropion hydrochloride ,
Bupropion ,
Bupropion hydrobromide 💬 		[2] SLC6A2,
SLC6A3 💬 		[8] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Neuroactive ligand signaling, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[7] 8, 18, 21, 96, 97, 171, 298 💬
45BV-101----[1] 8 💬
46Calvan (bevantolol hydrochloride)[1] Bevantolol[1] Bevantolol hydrochloride 💬 [8] ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		[44] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gap junction, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hormone signaling, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Regulation of lipolysis in adipocytes, Renin secretion, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 8 💬
47Calvan Tablets 100----[1] 8 💬
48Calvan® 100 mg----[1] 8 💬
49Cannabidiol[1] Cannabidiol[1] Cannabidiol 💬 [2] CNR1,
CNR2 💬 		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[20] 6, 8, 13, 19, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
50Cellavita HD Higher dose----[1] 8 💬
51Cellavita HD Lower Dose----[1] 8 💬
52Cellavita-HD----[1] 8 💬
53Cholesterol[1] Cholesterol[1] Cholesterol 💬 --[10] 8, 19, 71, 79, 90, 160, 222, 259, 261, 310 💬
54Citalopram[1] Citalopram[2] Citalopram hydrobromide ,
Citalopram 💬 		[1] SLC6A4 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬[7] 6, 8, 13, 18, 46, 98, 127 💬
55CKD-504[1] CKD-504---[1] 8 💬
56Coenzyme Q10----[11] 2, 5, 6, 8, 10, 18, 49, 57, 107, 113, 193 💬
57CoQ10----[4] 5, 6, 8, 96 💬
58Creatine[1] Creatine---[18] 1, 2, 3, 5, 6, 8, 13, 15, 21, 46, 49, 50, 97, 113, 156, 201, 256, 337 💬
59Creatine Monohydrate[1] Creatine---[5] 2, 8, 97, 113, 156 💬
60CYSTAGON----[3] 8, 19, 299 💬
61Cysteamine[1] Cysteamine[3] Cysteamine ,
Cysteamine hydrochloride ,
Cysteamine bitartrate 💬 		--[4] 8, 19, 21, 299 💬
62Cysteamine Bitartrate[1] Cysteamine[3] Cysteamine ,
Cysteamine hydrochloride ,
Cysteamine bitartrate 💬 		--[4] 8, 19, 21, 299 💬
63Deep Brain Stimulation----[5] 5, 6, 7, 8, 17 💬
64Delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD)[1] Cannabidiol[1] Cannabidiol 💬 [2] CNR1,
CNR2 💬 		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[1] 8 💬
65Deutetrabenazine[1] Deutetrabenazine[1] Deutetrabenazine 💬 [1] SLC18A2 💬 [8] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Neuroactive ligand signaling, Parkinson disease, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 8 💬
66Deutetrabenazine Oral Tablet [Austedo][1] Deutetrabenazine[1] Deutetrabenazine 💬 [1] SLC18A2 💬 [8] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Neuroactive ligand signaling, Parkinson disease, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 8 💬
67Dextromethorphan[1] Dextromethorphan[3] Dextromethorphan hydrobromide ,
Dextromethorphan ,
Dextromethorphan polistirex 💬 		[6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬 		[21] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[10] 2, 6, 8, 13, 21, 46, 85, 96, 97, 156 💬
68Dextromethorphan/quinidine 20mg/10mg (DM/Q 20mg/10mg)[2] Dextromethorphan,
Quinidine		[7] Quinidine gluconate ,
Quinidine polygalacturonate ,
Dextromethorphan hydrobromide ,
Quinidine sulfate ,
Dextromethorphan ,
Dextromethorphan polistirex ,
Quinidine 💬 		[12] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A,
SIGMAR1 💬 		[25] Adrenergic signaling in cardiomyocytes, Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Cadherin signaling, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, IgSF CAM signaling, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, Taste transduction, cAMP signaling pathway 💬[1] 8 💬
69Diagnostic Test: 11C-UCB-J PET-CT----[1] 8 💬
70Diagnostic Test: 18F-FDG PET-MR----[1] 8 💬
71Diagnostic Test: 7T MRI-scan----[1] 8 💬
72Diagnostic Test: Blood withdrawal----[4] 5, 7, 8, 127 💬
73Diagnostic Test: Body composition using a hand-held body fat monitor • Resting Metabolic Rate (RMR) using a ventilated hood system----[1] 8 💬
74Diagnostic Test: Clinical measures----[4] 5, 7, 8, 127 💬
75Diagnostic Test: computer vision, remote monitoring, blood, urine, wrist bands, mobile-app----[1] 8 💬
76Diagnostic Test: CSF collection via lumbar puncture----[1] 8 💬
77Digoxin[1] Digoxin[1] Digoxin 💬 [4] ATP1A1,
ATP1A2,
ATP1A3,
ATP1A4 💬 		[19] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Bile secretion, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cytoskeleton in muscle cells, Endocrine and other factor-regulated calcium reabsorption, Gastric acid secretion, Insulin secretion, Mineral absorption, Pancreatic secretion, Protein digestion and absorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Thyroid hormone signaling pathway, Thyroid hormone synthesis, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[7] 2, 8, 46, 57, 65, 67, 210 💬
78Dimebon----[1] 8 💬
79Dimebon (latrepirdine)[1] Latrepirdine[2] Latrepirdine ,
Latrepirdine dihydrochloride 💬 		[6] ACHE,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[23] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 8 💬
80Dimebon + Dextromethorphan[1] Dextromethorphan[3] Dextromethorphan hydrobromide ,
Dextromethorphan ,
Dextromethorphan polistirex 💬 		[6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬 		[21] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 8 💬
81Dimebon + Ketoconazole[1] Ketoconazole[1] Ketoconazole 💬 --[1] 8 💬
82Dimebon + Omeprazole[1] Omeprazole[3] Omeprazole ,
Omeprazole sodium ,
Omeprazole magnesium 💬 		[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[1] 8 💬
83Dimebon alone----[1] 8 💬
84Dimebon Dihydrochloride----[1] 8 💬
85Dimebon IR----[1] 8 💬
86Dimebon IR Tablet----[1] 8 💬
87Dimebon MR1----[1] 8 💬
88Dimebon MR2----[1] 8 💬
89Dimebon MR3----[1] 8 💬
90Dimebon MR4----[1] 8 💬
91Dimebon Transdermal----[1] 8 💬
92Divalproex----[1] 8 💬
93Epigallocatechin[1] Epigallocatechin---[5] 8, 13, 28, 85, 113 💬
94ER2001[1] ER2001---[1] 8 💬
95ER2001 injection[1] ER2001---[1] 8 💬
96ER2001 intravenous injection[1] ER2001---[1] 8 💬
97Ethyl Icosapent[1] Icosapent[1] Icosapent 💬 --[1] 8 💬
98Ethyl-EPA----[1] 8 💬
99Ethyl-EPA (Miraxion™)----[1] 8 💬
100Ethyl-Icosapent[1] Icosapent[1] Icosapent 💬 --[1] 8 💬
101Fenofibrate[1] Fenofibrate[1] Fenofibrate 💬 [1] PPARA 💬 [10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[6] 8, 79, 93, 94, 97, 265 💬
102Genetic: AB-1001 Gene Therapy----[1] 8 💬
103Genetic: Blood sample----[5] 8, 13, 61, 280, 294 💬
104Genetic: intra-striatal rAAV5-miHTT----[1] 8 💬
105Genetic: Intraparenchymal rAAV1 - (mi)RNA HTT----[1] 8 💬
106Genetic: Mutation in the gene----[1] 8 💬
107Genetic: NestaCell®----[1] 8 💬
108Genetic: Non invasive prenatal diagnosis----[3] 8, 113, 206 💬
109Genetic: SPK-10001----[1] 8 💬
110Graft intracerebral of foetal neurons----[1] 8 💬
111GSK356278----[1] 8 💬
112Haloperidol[1] Haloperidol[3] Haloperidol ,
Haloperidol decanoate ,
Haloperidol lactate 💬 		[1] DRD2 💬 [10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 8 💬
113Haloperidol 2Mg Tab[1] Haloperidol[3] Haloperidol ,
Haloperidol decanoate ,
Haloperidol lactate 💬 		[1] DRD2 💬 [10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 8 💬
114High doses of Thiamine y Biotin[2] Biotin,
Thiamine		[4] Biotin ,
Thiamine hydrochloride ,
Thiamine mononitrate ,
Thiamine 💬 		--[1] 8 💬
115HNSC-01----[1] 8 💬
116Hyperium[1] Rilmenidine[1] Rilmenidine 💬 [3] ADRA2A,
ADRA2B,
ADRA2C 💬 		[4] Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[1] 8 💬
117Icosapent[1] Icosapent[1] Icosapent 💬 --[1] 8 💬
118Idebenone[1] Idebenone[1] Idebenone 💬 --[9] 6, 8, 13, 17, 18, 21, 113, 115, 302 💬
119ISIS 443139 10 mg----[1] 8 💬
120ISIS 443139 120 mg----[1] 8 💬
121ISIS 443139 30 mg----[1] 8 💬
122ISIS 443139 60 mg----[1] 8 💬
123ISIS 443139 90 mg----[1] 8 💬
124Ketoconazole[1] Ketoconazole[1] Ketoconazole 💬 --[3] 8, 13, 75 💬
125LAQUINIMOD[1] Laquinimod[1] Laquinimod sodium 💬 --[4] 8, 13, 49, 96 💬
126Laquinimod capsules 0.5 mg[1] Laquinimod[1] Laquinimod sodium 💬 --[2] 8, 96 💬
127Latrepirdine[1] Latrepirdine[2] Latrepirdine ,
Latrepirdine dihydrochloride 💬 		[6] ACHE,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[23] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 8 💬
128LAX-101[1] LAX-101---[1] 8 💬
129Lithium----[5] 2, 5, 6, 7, 8 💬
130LMI070----[2] 3, 8 💬
131LPM3770164 sustained release tablet----[1] 8 💬
132LPM3770164 sustained release tablet simulant----[1] 8 💬
133Lumbar Punction----[1] 8 💬
134MBF-015 16 mg oral capsules----[1] 8 💬
135MD: 30mg WVE-003[1] WVE-003---[1] 8 💬
136Melatonin[1] Melatonin[1] Melatonin 💬 [2] MTNR1A,
MTNR1B 💬 		[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬[18] 2, 6, 8, 13, 37, 46, 49, 72, 78, 86, 90, 96, 97, 145, 149, 159, 202, 265 💬
137Memantine[1] Memantine[2] Memantine hydrochloride ,
Memantine 💬 		[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[21] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[8] 2, 6, 8, 13, 49, 127, 205, 206 💬
138Metformin[1] Metformin[2] Metformin hydrochloride ,
Metformin 💬 		[2] PRKAA1,
PRKAA2 💬 		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[31] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬
139Minocycline[1] Minocycline[2] Minocycline hydrochloride ,
Minocycline 💬 		--[14] 2, 6, 8, 13, 46, 85, 90, 94, 97, 162, 201, 206, 280, 299 💬
140Moderate doses of Thiamine y Biotin[2] Biotin,
Thiamine		[4] Biotin ,
Thiamine hydrochloride ,
Thiamine mononitrate ,
Thiamine 💬 		--[1] 8 💬
141N.a.----[11] 3, 6, 8, 13, 46, 63, 96, 97, 240, 256, 271 💬
142NAC----[1] 8 💬
143Neflamapimod[1] Neflamapimod[1] Neflamapimod 💬 [4] MAPK11,
MAPK12,
MAPK13,
MAPK14 💬 		[64] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Alcoholic liver disease, Amyotrophic lateral sclerosis, C-type lectin receptor signaling pathway, Cadherin signaling, Cellular senescence, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Coronavirus disease, Diabetic cardiomyopathy, Dopaminergic synapse, Efferocytosis, Epithelial cell signaling in Helicobacter pylori infection, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hepatitis B, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, IL-17 signaling pathway, IgSF CAM signaling, Inflammatory mediator regulation of TRP channels, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Leukocyte transendothelial migration, Lipid and atherosclerosis, MAPK signaling pathway, NOD-like receptor signaling pathway, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Oocyte meiosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Platelet activation, Prion disease, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rap1 signaling pathway, Relaxin signaling pathway, Retrograde endocannabinoid signaling, Salmonella infection, Shigellosis, Signaling pathways regulating pluripotency of stem cells, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Thermogenesis, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Yersinia infection 💬[1] 8 💬
144Nicotinamide[1] Nicotinamide[1] Niacinamide 💬 --[19] 2, 5, 6, 7, 8, 17, 18, 21, 46, 49, 60, 63, 65, 85, 97, 107, 162, 191, 302 💬
145Nicotinamide riboside[2] Nicotinamide,
Nicotinamide riboside		[1] Niacinamide 💬 --[14] 2, 5, 6, 7, 8, 17, 18, 21, 49, 60, 65, 85, 97, 191 💬
146Nicotinamide Riboside (NR)[2] Nicotinamide,
Nicotinamide riboside		[1] Niacinamide 💬 --[1] 8 💬
147Nilotinib[1] Nilotinib[1] Nilotinib 💬 [4] ABL1,
KIT,
PDGFRA,
PDGFRB 💬 		[35] Acute myeloid leukemia, Axon guidance, Breast cancer, Cadherin signaling, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, Human papillomavirus infection, IgSF CAM signaling, Integrin signaling, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬[5] 6, 8, 34, 51, 86 💬
148Nilotinib 150 MG[1] Nilotinib[1] Nilotinib 💬 [4] ABL1,
KIT,
PDGFRA,
PDGFRB 💬 		[35] Acute myeloid leukemia, Axon guidance, Breast cancer, Cadherin signaling, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, Human papillomavirus infection, IgSF CAM signaling, Integrin signaling, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬[1] 8 💬
149OLANZAPINE[1] Olanzapine[2] Olanzapine ,
Olanzapine pamoate 💬 		[11] ADRA1A,
ADRA1B,
ADRA1D,
DRD2,
DRD3,
DRD4,
HRH1,
HTR2A,
HTR2B,
HTR2C,
HTR6 💬 		[18] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Salivary secretion, Serotonergic synapse, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 2, 8 💬
150Omeprazole[1] Omeprazole[3] Omeprazole ,
Omeprazole sodium ,
Omeprazole magnesium 💬 		[2] ATP4A,
ATP4B 💬 		[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬[18] 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
151OMS643762----[1] 8 💬
152OSU 6162----[2] 6, 8 💬
153OSU6162----[2] 6, 8 💬
154OSU6162 similar to (-)-OSU 6162----[2] 6, 8 💬
155Other: 31-Phosphorus RMN Spectroscopy[1] Phosphorus---[1] 8 💬
156Other: Cognitive evaluation----[1] 8 💬
157Other: Imitation (sham) surgery----[1] 8 💬
158Other: PK microsampling of blood----[4] 6, 8, 13, 97 💬
159Other: Registry----[4] 6, 8, 13, 97 💬
160PBF-999----[1] 8 💬
161PBF-999 / 160 mg----[1] 8 💬
162PBF-999 / 320 mg----[1] 8 💬
163PBT2----[1] 8 💬
164PF-02545920----[1] 8 💬
165Phosphorus[1] Phosphorus---[2] 8, 238 💬
166PL101----[1] 8 💬
167Pridiopidine----[1] 8 💬
168Pridopidina----[1] 8 💬
169Pridopidine[1] Pridopidine[2] Pridopidine ,
Pridopidine hydrochloride 💬 		[1] DRD2 💬 [10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 2, 6, 8 💬
170Pridopidine (90 mg)[1] Pridopidine[2] Pridopidine ,
Pridopidine hydrochloride 💬 		[1] DRD2 💬 [10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 8 💬
171PRIDOPIDINE HYDROCHLORIDE[1] Pridopidine[2] Pridopidine ,
Pridopidine hydrochloride 💬 		[1] DRD2 💬 [10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 8 💬
172PS659----[2] 8, 18 💬
173PTC518----[1] 8 💬
174PTC518 tablet 20 mg----[1] 8 💬
175PTC518 tablet 5 mg----[1] 8 💬
176Quinidine[1] Quinidine[4] Quinidine gluconate ,
Quinidine polygalacturonate ,
Quinidine sulfate ,
Quinidine 💬 		[6] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬 		[5] Adrenergic signaling in cardiomyocytes, Cadherin signaling, Dopaminergic synapse, IgSF CAM signaling, Taste transduction 💬[3] 2, 8, 13 💬
177RAAV5-miHTT[1] AMT-130---[1] 8 💬
178Ramelteon[1] Ramelteon[1] Ramelteon 💬 [2] MTNR1A,
MTNR1B 💬 		[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬[3] 6, 8, 46 💬
179Resveratrol[1] Resveratrol---[10] 2, 6, 8, 18, 46, 57, 89, 97, 113, 299 💬
180RG6042, formerly ISIS 443139, IONIS-HTTRx----[1] 8 💬
181RG6496----[1] 8 💬
182Rilmenidine[1] Rilmenidine[1] Rilmenidine 💬 [3] ADRA2A,
ADRA2B,
ADRA2C 💬 		[4] Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[1] 8 💬
183RILUZOLE[1] Riluzole[1] Riluzole 💬 [14] GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[24] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
184Risperidone[1] Risperidone[1] Risperidone 💬 [2] DRD2,
HTR2A 💬 		[13] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬[6] 8, 74, 156, 179, 187, 206 💬
185Risperidone 1Mg Tab[1] Risperidone[1] Risperidone 💬 [2] DRD2,
HTR2A 💬 		[13] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬[1] 8 💬
186Ro 723-4292/F02----[1] 8 💬
187RO7234292----[1] 8 💬
188RO7234292 (RG6042)----[1] 8 💬
189Rolipram[1] Rolipram[1] Rolipram 💬 [4] PDE4A,
PDE4B,
PDE4C,
PDE4D 💬 		[4] Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬[2] 8, 13 💬
190RP 103----[2] 8, 19 💬
191RP103----[2] 8, 19 💬
192SAD: 30mg WVE-003[1] WVE-003---[1] 8 💬
193SAD: 60mg WVE-003[1] WVE-003---[1] 8 💬
194SAD: 90mg WVE-003[1] WVE-003---[1] 8 💬
195SAGE-718----[2] 6, 8 💬
196SBT-020----[1] 8 💬
197SD-809----[1] 8 💬
198Selisistat[1] Selisistat---[1] 8 💬
199SEN0014196----[1] 8 💬
200SEN0014196 (High Dose)----[1] 8 💬
201SEN0014196 (Low Dose)----[1] 8 💬
202SKY-0515----[1] 8 💬
203Sodium phenylbutyrate[1] Phenylbutyric acid[1] Sodium phenylbutyrate 💬 --[5] 2, 3, 8, 18, 251 💬
204SOM3355----[1] 8 💬
205SOM3355 (bevantolol hydrochloride)[1] Bevantolol[1] Bevantolol hydrochloride 💬 [8] ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		[44] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gap junction, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hormone signaling, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Regulation of lipolysis in adipocytes, Renin secretion, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 8 💬
206SOM3355 100mg BID----[1] 8 💬
207SOM3355 200 mg capsules----[1] 8 💬
208SOM3355 200mg BID----[1] 8 💬
209SOM3355 300 mg capsules----[1] 8 💬
210SRP-1005----[1] 8 💬
211SRX246----[2] 8, 206 💬
212SS-20----[1] 8 💬
213Tetrabenazine[1] Tetrabenazine[1] Tetrabenazine 💬 [1] SLC18A2 💬 [8] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Neuroactive ligand signaling, Parkinson disease, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 8 💬
214Tetrabenazine withdrawal[1] Tetrabenazine[1] Tetrabenazine 💬 [1] SLC18A2 💬 [8] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Neuroactive ligand signaling, Parkinson disease, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 8 💬
215Thiamine[1] Thiamine[3] Thiamine hydrochloride ,
Thiamine mononitrate ,
Thiamine 💬 		--[5] 8, 13, 93, 265, 340 💬
216Tiapridal----[1] 8 💬
217Tominersen[1] Tominersen[1] Tominersen 💬 [1] HTT 💬 [2] Huntington disease, Pathways of neurodegeneration - multiple diseases 💬[1] 8 💬
218Triheptanoin[1] Triheptanoin[1] Triheptanoin 💬 --[12] 2, 8, 65, 149, 156, 248, 256, 257, 317, 318, 324, 344 💬
219Triheptanoin 1g/kg/day[1] Triheptanoin[1] Triheptanoin 💬 --[1] 8 💬
220Triheptanoin oil[1] Triheptanoin[1] Triheptanoin 💬 --[1] 8 💬
221TV-5600----[3] 8, 13, 96 💬
222TV-7820----[1] 8 💬
223Ubiquinol[1] Ubiquinol---[4] 6, 8, 17, 57 💬
224Ursodiol----[5] 8, 20, 93, 234, 299 💬
225UX007----[5] 8, 248, 256, 257, 344 💬
226Valbenazine[1] Valbenazine[2] Valbenazine ,
Valbenazine tosylate 💬 		[1] SLC18A2 💬 [8] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Neuroactive ligand signaling, Parkinson disease, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 8 💬
227Vitamin B7[1] Biotin[1] Biotin 💬 --[1] 8 💬
228VO659[1] VO659---[2] 8, 18 💬
229Votoplam[1] Votoplam[1] Votoplam 💬 [1] HTT 💬 [2] Huntington disease, Pathways of neurodegeneration - multiple diseases 💬[1] 8 💬
230Votoplam (blinded)[1] Votoplam[1] Votoplam 💬 [1] HTT 💬 [2] Huntington disease, Pathways of neurodegeneration - multiple diseases 💬[1] 8 💬
231VX-745----[1] 8 💬
232VX15/2503----[2] 8, 13 💬
233Warfarin[1] Warfarin[3] Warfarin sodium ,
Warfarin potassium ,
Warfarin 💬 		[2] NQO1,
VKORC1 💬 		[5] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬[15] 6, 8, 13, 19, 46, 48, 49, 66, 85, 86, 88, 91, 96, 97, 222 💬
234WVE-003[1] WVE-003---[1] 8 💬
235WVE-120101----[1] 8 💬
236WVE-120102----[1] 8 💬
237Xenazine----[1] 8 💬
238Zoloft 50Mg Tablet----[1] 8 💬