Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 HRH1 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Promethazine teoclate 💬 Promethazine [2] 6, 96 💬
2 HRH1 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Desloratadine 💬 Desloratadine [1] 13 💬
3 HRH1 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Doxepin hydrochloride 💬 Doxepin [1] 6 💬
4 HRH1 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Histamine phosphate 💬 Histamine [1] 13 💬
5 HRH1 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Chlorphenamine 💬 Chlorpheniramine [1] 14 💬
6 HRH1 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Chlorpheniramine maleate 💬 Chlorpheniramine [1] 14 💬
7 HRH1 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Diphenhydramine salicylate 💬 Diphenhydramine [11] 11, 13, 19, 49, 51, 70, 86, 96, 222, 256, 300 💬
8 HRH1 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Levocetirizine 💬 Levocetirizine [1] 61 💬
9 HRH1 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Doxepin 💬 Doxepin [1] 6 💬
10 HRH1 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Diphenhydramine hydrochloride 💬 Diphenhydramine [11] 11, 13, 19, 49, 51, 70, 86, 96, 222, 256, 300 💬
11 HRH1 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Cetirizine 💬 Cetirizine [6] 13, 19, 28, 35, 300, 309 💬
12 HRH1 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Promethazine 💬 Promethazine [2] 6, 96 💬
13 HRH1 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Levocetirizine dihydrochloride 💬 Levocetirizine [1] 61 💬
14 HRH1 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Fexofenadine 💬 Fexofenadine [4] 6, 13, 19, 46 💬
15 HRH1 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Promethazine hydrochloride 💬 Promethazine [2] 6, 96 💬
16 HRH1 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Clemastine 💬 Clemastine [2] 13, 179 💬
17 HRH1 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Loratadine 💬 Loratadine [5] 13, 19, 46, 89, 98 💬
18 HRH1 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Olanzapine pamoate 💬 Olanzapine [2] 2, 8 💬
19 HRH1 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Clemastine fumarate 💬 Clemastine [2] 13, 179 💬
20 HRH1 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Cetirizine hydrochloride 💬 Cetirizine [6] 13, 19, 28, 35, 300, 309 💬
21 HRH1 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Dexchlorpheniramine 💬 Dexchlorpheniramine [1] 13 💬
22 HRH1 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Olanzapine 💬 Olanzapine [2] 2, 8 💬
23 HRH1 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Rupatadine 💬 Rupatadine [1] 46 💬
24 HRH1 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Diphenhydramine 💬 Diphenhydramine [11] 11, 13, 19, 49, 51, 70, 86, 96, 222, 256, 300 💬
25 HRH1 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Fexofenadine hydrochloride 💬 Fexofenadine [4] 6, 13, 19, 46 💬
26 HRH1 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Chlorpromazine 💬 Chlorpromazine [1] 254 💬
27 HRH1 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Diphenhydramine citrate 💬 Diphenhydramine [11] 11, 13, 19, 49, 51, 70, 86, 96, 222, 256, 300 💬
28 HRH1 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Rupatadine fumarate 💬 Rupatadine [1] 46 💬
29 HRH1 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Histamine 💬 Histamine [1] 13 💬
30 HRH1 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Chlorpromazine hydrochloride 💬 Chlorpromazine [1] 254 💬