Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Abatacept 💬[1] Abatacept[1] Abatacept[2] CD80,
CD86 💬 		[14] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecule (CAM) interaction, Graft-versus-host disease, IgSF CAM signaling, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Virion - Adenovirus 💬[28] 2, 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 223, 271, 284, 285, 300 💬
2 Acetaminophen 💬[1] Acetaminophen[2] Acetaminophen; Paracetamol[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[19] 11, 13, 19, 34, 35, 46, 49, 51, 63, 70, 77, 86, 96, 222, 231, 256, 271, 300, 337 💬
3 Acetylcholine chloride 💬[1] Acetylcholine[1] Acetylcholine[21] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5,
CHRNA1,
CHRNA10,
CHRNA2,
CHRNA3,
CHRNA4,
CHRNA5,
CHRNA6,
CHRNA7,
CHRNA9,
CHRNB1,
CHRNB2,
CHRNB3,
CHRNB4,
CHRND,
CHRNE,
CHRNG 💬 		[17] Alzheimer disease, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, Virion - Ebolavirus, Lyssavirus and Morbillivirus, cAMP signaling pathway 💬[1] 11 💬
4 Algeldrate 💬[1] Aluminum hydroxide[1] Aluminum hydroxide--[1] 11 💬
5 Almagate 💬[1] Aluminum hydroxide[1] Aluminum hydroxide--[1] 11 💬
6 Aluminum hydroxide 💬[1] Aluminum hydroxide[1] Aluminum hydroxide--[1] 11 💬
7 Amifampridine 💬[1] Amifampridine[2] Amifampridine; Amifampridine Phosphate[7] KCNA1,
KCNA2,
KCNA4,
KCNA6,
KCNC3,
KCND2,
KCND3 💬 		[5] Cortisol synthesis and secretion, Cushing syndrome, IgSF CAM signaling, Serotonergic synapse, Spinocerebellar ataxia 💬[3] 3, 11, 12 💬
8 Amifampridine phosphate 💬[1] Amifampridine[2] Amifampridine; Amifampridine Phosphate[7] KCNA1,
KCNA2,
KCNA4,
KCNA6,
KCNC3,
KCND2,
KCND3 💬 		[5] Cortisol synthesis and secretion, Cushing syndrome, IgSF CAM signaling, Serotonergic synapse, Spinocerebellar ataxia 💬[3] 3, 11, 12 💬
9 Apraclonidine 💬[1] Apraclonidine[1] Apraclonidine[3] ADRA2A,
ADRA2B,
ADRA2C 💬 		[4] Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[1] 11 💬
10 Apraclonidine hydrochloride 💬[1] Apraclonidine[1] Apraclonidine[3] ADRA2A,
ADRA2B,
ADRA2C 💬 		[4] Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[1] 11 💬
11 Azathioprine 💬[1] Azathioprine[2] Azathioprine; AZATIOPRINA--[26] 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 55, 57, 63, 65, 66, 84, 85, 93, 94, 95, 96, 97, 162, 223, 300 💬
12 Azathioprine sodium 💬[1] Azathioprine[2] Azathioprine; Azatioprina--[26] 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 55, 57, 63, 65, 66, 84, 85, 93, 94, 95, 96, 97, 162, 223, 300 💬
13 Batoclimab 💬[1] Batoclimab[1] Batoclimab--[2] 11, 14 💬
14 Belimumab 💬[1] Belimumab[1] Belimumab[1] TNFSF13B 💬 [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[17] 11, 13, 43, 44, 46, 48, 49, 50, 51, 53, 63, 66, 95, 222, 223, 296, 300 💬
15 Blinatumomab 💬[1] Blinatumomab[1] Blinatumomab[4] CD19,
CD3D,
CD3E,
CD3G 💬 		[13] B cell receptor signaling pathway, Chagas disease, Epstein-Barr virus infection, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human immunodeficiency virus 1 infection, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Primary immunodeficiency, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬[4] 11, 46, 49, 222 💬
16 Bortezomib 💬[1] Bortezomib[1] BORTEZOMIB[1] PSMB5 💬 [8] Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia 💬[19] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 172, 222, 223, 228, 256, 283, 288, 331 💬
17 Carmustine 💬[1] Carmustine[2] CARMUSTINA; Carmustine--[5] 11, 13, 14, 28, 60 💬
18 Cladribine 💬[1] Cladribine[2] CLADRIBINA; CLADRIBINE[1] RRM1 💬 [4] Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬[3] 11, 13, 94 💬
19 Cyclophosphamide 💬[1] Cyclophosphamide[5] Ciclofosfamida; CICLOFOSFAMIDE; Cyclophosphamid; Cyclophosphamide; CYCLOPHOSPHAMIDE MONOHYDRATE--[50] 11, 13, 14, 16, 19, 20, 26, 28, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 62, 63, 65, 66, 84, 93, 96, 162, 164, 172, 205, 221, 222, 223, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
20 Cyclophosphamide 💬[1] Cyclophosphamide[5] Ciclofosfamida; CICLOFOSFAMIDE; Cyclophosphamid; Cyclophosphamide; CYCLOPHOSPHAMIDE MONOHYDRATE--[50] 11, 13, 14, 16, 19, 20, 26, 28, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 62, 63, 65, 66, 84, 93, 96, 162, 164, 172, 205, 221, 222, 223, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬
21 Cyclosporine 💬[1] Cyclosporine[7] CICLOSPORIN; CICLOSPORINA; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine; Cyclosporine A[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[39] 11, 14, 19, 20, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 67, 90, 95, 97, 107, 118, 162, 164, 222, 223, 226, 228, 234, 283, 284, 285, 302 💬
22 Cytarabine 💬[1] Cytarabine[2] CITARABINA; Cytarabine--[8] 11, 13, 14, 25, 34, 49, 60, 65 💬
23 Cytarabine hydrochloride 💬[1] Cytarabine[2] CITARABINA; Cytarabine--[8] 11, 13, 14, 25, 34, 49, 60, 65 💬
24 Diphenhydramine 💬[1] Diphenhydramine[2] Diphenhydramine; Diphenhydramine hydrochloride[1] HRH1 💬 [4] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[12] 11, 13, 19, 49, 51, 63, 70, 86, 96, 222, 256, 300 💬
25 Diphenhydramine citrate 💬[1] Diphenhydramine[2] Diphenhydramine; Diphenhydramine hydrochloride[1] HRH1 💬 [4] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[12] 11, 13, 19, 49, 51, 63, 70, 86, 96, 222, 256, 300 💬
26 Diphenhydramine hydrochloride 💬[1] Diphenhydramine[2] Diphenhydramine; Diphenhydramine hydrochloride[1] HRH1 💬 [4] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[12] 11, 13, 19, 49, 51, 63, 70, 86, 96, 222, 256, 300 💬
27 Diphenhydramine salicylate 💬[1] Diphenhydramine[2] Diphenhydramine; Diphenhydramine Hydrochloride[1] HRH1 💬 [4] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[12] 11, 13, 19, 49, 51, 63, 70, 86, 96, 222, 256, 300 💬
28 Eculizumab 💬[1] Eculizumab[1] ECULIZUMAB[1] C5 💬 [11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[8] 11, 13, 14, 61, 62, 109, 221, 223 💬
29 Efalizumab 💬[1] Efalizumab[1] EFALIZUMAB[1] ITGAL 💬 [14] Cell adhesion molecule (CAM) interaction, Epstein-Barr virus infection, Human T-cell leukemia virus 1 infection, IgSF CAM signaling, Integrin signaling, Leukocyte transendothelial migration, Malaria, Natural killer cell mediated cytotoxicity, Neutrophil extracellular trap formation, Rap1 signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Staphylococcus aureus infection, Viral myocarditis 💬[10] 11, 13, 37, 46, 48, 53, 61, 95, 96, 221 💬
30 Efgartigimod alfa 💬[1] Efgartigimod alfa[2] Efgartigimod; EFGARTIGIMOD ALFA--[7] 11, 13, 14, 35, 53, 63, 162 💬
31 Empasiprubart 💬[1] Empasiprubart[1] Empasiprubart[1] C2 💬 [6] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease, Pertussis, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[3] 11, 14, 50 💬
32 Ephedrine 💬[1] Ephedrine[2] Ephedrine; EPHEDRINE HYDROCHLORIDE[9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬 		[16] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 11 💬
33 Ephedrine hydrochloride 💬[1] Ephedrine[2] Ephedrine; EPHEDRINE HYDROCHLORIDE[9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬 		[16] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 11 💬
34 Ephedrine sulfate 💬[1] Ephedrine[2] Ephedrine; EPHEDRINE HYDROCHLORIDE[9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬 		[16] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 11 💬
35 Etomidate 💬[1] Etomidate[1] Etomidate[1] GABRA1 💬 [8] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Taste transduction 💬[2] 6, 11 💬
36 Etoposide 💬[1] Etoposide[1] Etoposide--[12] 11, 13, 14, 26, 28, 34, 54, 60, 65, 85, 164, 331 💬
37 Etoposide phosphate 💬[1] Etoposide[1] Etoposide--[12] 11, 13, 14, 26, 28, 34, 54, 60, 65, 85, 164, 331 💬
38 Famciclovir 💬[1] Famciclovir[1] Famciclovir--[2] 11, 13 💬
39 Fludarabine 💬[1] Fludarabine[3] FLUDARABINA; Fludarabine; Fludarabine phosphate[1] RRM1 💬 [4] Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬[30] 11, 13, 14, 16, 19, 28, 34, 35, 36, 44, 46, 49, 50, 51, 60, 61, 62, 63, 65, 85, 96, 107, 164, 222, 223, 283, 284, 285, 286, 326 💬
40 Fludarabine phosphate 💬[1] Fludarabine[3] FLUDARABINA; Fludarabine; Fludarabine Phosphate[1] RRM1 💬 [4] Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬[30] 11, 13, 14, 16, 19, 28, 34, 35, 36, 44, 46, 49, 50, 51, 60, 61, 62, 63, 65, 85, 96, 107, 164, 222, 223, 283, 284, 285, 286, 326 💬
41 Galantamine 💬[1] Galantamine[2] GALANTAMINE; Galantamine hydrobromide[1] ACHE 💬 [3] Cholinergic synapse, Glycerophospholipid metabolism, Neuroactive ligand signaling 💬[3] 6, 11, 127 💬
42 Galantamine hydrobromide 💬[1] Galantamine[2] Galantamine; Galantamine hydrobromide[1] ACHE 💬 [3] Cholinergic synapse, Glycerophospholipid metabolism, Neuroactive ligand signaling 💬[3] 6, 11, 127 💬
43 Gefurulimab 💬[1] Gefurulimab[1] Gefurulimab[1] C5 💬 [11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[1] 11 💬
44 Inebilizumab 💬[1] Inebilizumab[1] Inebilizumab[1] CD19 💬 [5] B cell receptor signaling pathway, Epstein-Barr virus infection, Hematopoietic cell lineage, PI3K-Akt signaling pathway, Primary immunodeficiency 💬[8] 11, 13, 46, 49, 51, 53, 95, 300 💬
45 Iptacopan 💬[1] Iptacopan[1] Iptacopan[1] CFB 💬 [3] Complement and coagulation cascades, Coronavirus disease, Staphylococcus aureus infection 💬[8] 11, 61, 62, 63, 66, 109, 222, 223 💬
46 Iptacopan hydrochloride 💬[1] Iptacopan[1] Iptacopan[1] CFB 💬 [3] Complement and coagulation cascades, Coronavirus disease, Staphylococcus aureus infection 💬[8] 11, 61, 62, 63, 66, 109, 222, 223 💬
47 Leflunomide 💬[1] Leflunomide[2] Leflunomide; Leflunomidum[1] DHODH 💬 [1] Pyrimidine metabolism 💬[14] 11, 40, 46, 49, 53, 54, 66, 107, 162, 223, 224, 270, 271, 300 💬
48 Magnesium sulfate 💬[1] Magnesium sulfate[2] Magnesium sulfate; MAGNESIUM SULFATE HEPTAHYDRATE--[4] 11, 97, 296, 297 💬
49 Melphalan 💬[1] Melphalan[2] Melphalan; Melphalan Hydrochloride--[19] 11, 13, 14, 19, 20, 28, 34, 46, 60, 62, 65, 96, 107, 164, 222, 234, 284, 285, 299 💬
50 Melphalan hydrochloride 💬[1] Melphalan[2] Melphalan; Melphalan Hydrochloride--[19] 11, 13, 14, 19, 20, 28, 34, 46, 60, 62, 65, 96, 107, 164, 222, 234, 284, 285, 299 💬
51 Mesna 💬[1] Coenzyme M[1] Mesna--[12] 11, 13, 16, 44, 45, 49, 51, 60, 65, 85, 96, 164 💬
52 Methotrexate 💬[1] Methotrexate[5] Methotrexat; Methotrexate; METHOTREXATE SODIUM; Methylaminopterin; Metotrexato[2] DHFR,
DHFR2 💬 		[3] Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬[41] 11, 13, 14, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 223, 240, 256, 270, 271, 284, 285, 286, 326, 331 💬
53 Methotrexate sodium 💬[1] Methotrexate[5] Methotrexat; METHOTREXATE; METHOTREXATE SODIUM; Methylaminopterin; METOTREXATO[2] DHFR,
DHFR2 💬 		[3] Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬[41] 11, 13, 14, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 223, 240, 256, 270, 271, 284, 285, 286, 326, 331 💬
54 Methylprednisolone 💬[1] Methylprednisolone[3] Methylprednisolon; Methylprednisolone; METHYLPREDNISOLONE ACETATE[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[51] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 111, 127, 145, 162, 164, 211, 222, 223, 224, 271, 283, 284, 285, 296, 300 💬
55 Methylprednisolone acetate 💬[1] Methylprednisolone[3] Methylprednisolon; Methylprednisolone; METHYLPREDNISOLONE ACETATE[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[51] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 111, 127, 145, 162, 164, 211, 222, 223, 224, 271, 283, 284, 285, 296, 300 💬
56 Mycophenolate mofetil 💬[1] Mycophenolate mofetil[1] Mycophenolate mofetil[2] IMPDH1,
IMPDH2 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[38] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 57, 60, 61, 62, 63, 65, 66, 93, 95, 96, 118, 162, 164, 222, 223, 224, 226, 234, 283, 284, 285, 300 💬
57 Mycophenolate mofetil hydrochloride 💬[1] Mycophenolate mofetil[1] Mycophenolate mofetil[2] IMPDH1,
IMPDH2 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[38] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 57, 60, 61, 62, 63, 65, 66, 93, 95, 96, 118, 162, 164, 222, 223, 224, 226, 234, 283, 284, 285, 300 💬
58 Mycophenolate sodium 💬[1] Mycophenolic acid[5] Acido Micofenolico; MICOFENOLICO ACIDO; Mycophenolate; Mycophenolate sodium; Mycophenolic Acid[2] IMPDH1,
IMPDH2 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[11] 11, 43, 49, 51, 53, 60, 66, 96, 222, 223, 228 💬
59 Mycophenolic acid 💬[1] Mycophenolic acid[5] ACIDO MICOFENOLICO; MICOFENOLICO ACIDO; Mycophenolate; Mycophenolate sodium; Mycophenolic Acid[2] IMPDH1,
IMPDH2 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[11] 11, 43, 49, 51, 53, 60, 66, 96, 222, 223, 228 💬
60 Neostigmine 💬[1] Neostigmine[1] Neostigmine[1] ACHE 💬 [3] Cholinergic synapse, Glycerophospholipid metabolism, Neuroactive ligand signaling 💬[1] 11 💬
61 Neostigmine bromide 💬[1] Neostigmine[1] Neostigmine[1] ACHE 💬 [3] Cholinergic synapse, Glycerophospholipid metabolism, Neuroactive ligand signaling 💬[1] 11 💬
62 Neostigmine methylsulfate 💬[1] Neostigmine[1] Neostigmine[1] ACHE 💬 [3] Cholinergic synapse, Glycerophospholipid metabolism, Neuroactive ligand signaling 💬[1] 11 💬
63 Nipocalimab 💬[1] Nipocalimab[1] Nipocalimab--[6] 11, 14, 46, 49, 53, 61 💬
64 Ocrelizumab 💬[1] Ocrelizumab[2] Ocrelizumab; RhuMAb 2H7[1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[4] 11, 13, 46, 49 💬
65 Ofatumumab 💬[1] Ofatumumab[2] HuMax-CD20; OFATUMUMAB[1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[6] 11, 13, 35, 46, 222, 223 💬
66 Pixantrone 💬[1] Pixantrone[1] Pixantrone--[2] 11, 13 💬
67 Pixantrone dimaleate 💬[1] Pixantrone[1] Pixantrone--[2] 11, 13 💬
68 Povetacicept 💬[1] Povetacicept[1] Povetacicept[1] TNFRSF13B 💬 [3] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, Primary immunodeficiency 💬[5] 11, 61, 63, 66, 222 💬
69 Pozelimab 💬[1] Pozelimab[1] Pozelimab[1] C5 💬 [11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[3] 11, 15, 62 💬
70 Prednisolone 💬[1] Prednisolone[3] Prednisolona; Prednisolone; Prednisolonum[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[48] 3, 11, 13, 14, 18, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 54, 56, 57, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 111, 113, 145, 162, 222, 223, 251, 269, 271, 296, 299, 300 💬
71 Prednisone 💬[1] Prednisone[2] PREDNISONA; Prednisone[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[58] 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 127, 145, 162, 164, 205, 222, 223, 224, 228, 251, 269, 283, 284, 285, 288, 299, 300, 303, 307, 331 💬
72 Pyridostigmine bromide 💬[1] Pyridostigmine[2] Pyridostigmine; PYRIDOSTIGMINE BROMIDE[1] ACHE 💬 [3] Cholinergic synapse, Glycerophospholipid metabolism, Neuroactive ligand signaling 💬[5] 3, 6, 11, 51, 256 💬
73 Ravulizumab 💬[1] Ravulizumab[1] RAVULIZUMAB[1] C5 💬 [11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[8] 2, 11, 13, 50, 62, 66, 109, 224 💬
74 Remibrutinib 💬[1] Remibrutinib[2] LOU064; Remibrutinib[1] BTK 💬 [7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[3] 11, 13, 53 💬
75 Rituximab 💬[1] Rituximab[1] Rituximab[1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[54] 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 88, 93, 94, 96, 97, 162, 172, 222, 223, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
76 Rozanolixizumab 💬[1] Rozanolixizumab[2] ROZANOLIXIZUMAB; UCB7665--[3] 11, 14, 63 💬
77 Satralizumab 💬[1] Satralizumab[1] Satralizumab[1] IL6R 💬 [11] Coronavirus disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[4] 11, 13, 86, 113 💬
78 Sodium chloride 💬[1] Sodium chloride[3] NaCl; SODIUM CHLORIDE; Sodium Chloride Solution--[31] 2, 6, 11, 13, 14, 22, 34, 41, 46, 50, 51, 53, 60, 65, 67, 70, 85, 96, 97, 124, 168, 193, 214, 215, 226, 227, 228, 271, 288, 298, 299 💬
79 Sufentanil 💬[1] Sufentanil[1] Sufentanil[1] OPRM1 💬 [5] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[5] 11, 22, 46, 70, 280 💬
80 Sufentanil citrate 💬[1] Sufentanil[1] Sufentanil[1] OPRM1 💬 [5] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[5] 11, 22, 46, 70, 280 💬
81 Sugammadex sodium 💬[1] Sugammadex[1] Sugammadex--[1] 11 💬
82 Tacrolimus 💬[1] Tacrolimus[1] Tacrolimus[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[37] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 57, 60, 61, 62, 63, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 223, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
83 Tacrolimus 💬[1] Tacrolimus[1] Tacrolimus[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[37] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 57, 60, 61, 62, 63, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 223, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
84 Talquetamab 💬[1] Talquetamab[1] Talquetamab[1] CD3E 💬 [11] Chagas disease, Epstein-Barr virus infection, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human immunodeficiency virus 1 infection, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬[2] 11, 28 💬
85 Tocilizumab 💬[1] Tocilizumab[2] BAT1806; Tocilizumab[1] IL6R 💬 [11] Coronavirus disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[26] 2, 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 65, 86, 107, 149, 153, 223, 266, 271, 298, 331 💬
86 Tofacitinib 💬[1] Tofacitinib[2] Tofacitinib; TOFACITINIB CITRATE[4] JAK1,
JAK2,
JAK3,
TYK2 💬 		[39] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease, Efferocytosis, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[23] 2, 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 56, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
87 Tofacitinib citrate 💬[1] Tofacitinib[2] Tofacitinib; TOFACITINIB CITRATE[4] JAK1,
JAK2,
JAK3,
TYK2 💬 		[39] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease, Efferocytosis, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Hormone signaling, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬[23] 2, 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 56, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
88 Tolebrutinib 💬[1] Tolebrutinib[1] Tolebrutinib[1] BTK 💬 [7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[2] 11, 13 💬
89 Zilucoplan 💬[1] Zilucoplan[1] Zilucoplan[1] C5 💬 [11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[3] 2, 11, 62 💬
90 Zilucoplan sodium 💬[1] Zilucoplan[1] Zilucoplan[1] C5 💬 [11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[3] 2, 11, 62 💬