Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Abatacept 💬[1] Abatacept[2] ABATACEPT; Orencia[2] CD80,
CD86 💬 		[13] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Virion - Adenovirus 💬[26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
2 Acetaminophen 💬[1] Acetaminophen[4] Acetaminophen; PARACETAMOL; Tylenol; Ultracet[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[15] 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
3 Acetazolamide 💬[1] Acetazolamide[1] Acetazolamide[13] CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬 		[7] Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬[6] 13, 90, 115, 155, 225, 230 💬
4 Acetylcysteine 💬[1] Acetylcysteine[3] Acetylcysteine; Mucomyst; N-acetylcysteine--[21] 6, 13, 19, 20, 21, 49, 51, 53, 58, 63, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337 💬
5 Acyclovir 💬[1] Acyclovir[3] ACICLOVIR; Acycloguanosine; Acyclovir--[5] 13, 28, 46, 53, 60 💬
6 Adenosine 💬[1] Adenosine[2] Adenosine; Ginseng[4] ADORA1,
ADORA2A,
ADORA2B,
ADORA3 💬 		[12] Alcoholism, Calcium signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 13, 58, 65 💬
7 Alanine 💬[1] Alanine[2] Alanine; L-alanine--[4] 6, 13, 298, 299 💬
8 Albendazole 💬[1] Albendazole[2] Albendazole; Eskazole--[1] 96 💬
9 Albuterol 💬[1] Salbutamol[3] Albuterol; Salbutamol; Ventolin[1] ADRB2 💬 [9] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[12] 3, 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
10 Alemtuzumab 💬[1] Alemtuzumab[4] Alemtuzumab; Campath; Lemtrada; MABCAMPATH[1] CD52 💬 [1] 💬[22] 13, 15, 19, 20, 36, 43, 44, 46, 49, 51, 60, 62, 63, 65, 85, 96, 164, 234, 283, 284, 285, 326 💬
11 Alfuzosin 💬[1] Alfuzosin[1] Alfuzosin[1] ADRA1A 💬 [7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 13 💬
12 Amantadine 💬[1] Amantadine[3] AMANTADINE; AMANTADINE HYDROCHLORIDE; GOCOVRI[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[4] 6, 8, 13, 127 💬
13 Amiloride 💬[1] Amiloride[3] Amiloride; Amiloride Hydrochloride; Midamor[3] SCNN1A,
SCNN1B,
SCNN1G 💬 		[2] Aldosterone-regulated sodium reabsorption, Taste transduction 💬[4] 13, 67, 225, 299 💬
14 Amlodipine 💬[1] Amlodipine[1] Amlodipine[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 51, 67, 298 💬
15 Ampicillin 💬[1] Ampicillin[1] ABPC--[1] 84 💬
16 Anakinra 💬[1] Anakinra[2] Anakinra; Kineret[2] IL1R1,
IL1R2 💬 		[15] Amoebiasis, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Pathogenic Escherichia coli infection, Prostate cancer, Shigellosis, Th17 cell differentiation, Transcriptional misregulation in cancer 💬[18] 2, 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
17 Anhydrous lactose 💬[1] Lactose[1] Lactose--[6] 2, 6, 13, 97, 228, 310 💬
18 Arbaclofen 💬[1] Arbaclofen[2] Arbaclofen; BACLOFEN[2] GABBR1,
GABBR2 💬 		[7] Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬[2] 13, 206 💬
19 Arbaclofen placarbil 💬[1] Arbaclofen Placarbil[1] Arbaclofen Placarbil[2] GABBR1,
GABBR2 💬 		[7] Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬[1] 13 💬
20 Armodafinil 💬[1] Armodafinil[2] Armodafinil; Modafinil[1] SLC6A3 💬 [7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[3] 6, 13, 84 💬
21 Aspartame 💬[1] Aspartame[0] [2] TAS1R2,
TAS1R3 💬 		[2] Carbohydrate digestion and absorption, Taste transduction 💬-
22 Aspirin 💬[1] Acetylsalicylic acid[2] ACETYLSALICYLIC ACID; Aspirin[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[12] 13, 22, 46, 49, 51, 58, 64, 86, 113, 158, 210, 231 💬
23 Atacicept 💬[1] Atacicept[2] Atacicept; TACI-Fc5[2] TNFSF13,
TNFSF13B 💬 		[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[4] 13, 46, 49, 66 💬
24 Atomoxetine 💬[1] Atomoxetine[2] Atomoxetine; Strattera[1] SLC6A2 💬 [1] Synaptic vesicle cycle 💬[4] 6, 8, 13, 17 💬
25 Atorvastatin 💬[1] Atorvastatin[3] Atorvastatin; Atorvastatin calcium; Lipitor[1] HMGCR 💬 [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[19] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
26 Azathioprine 💬[1] Azathioprine[3] Azathioprine; Azatioprina; Imuran--[21] 6, 11, 13, 19, 35, 42, 43, 44, 45, 46, 49, 63, 65, 66, 85, 93, 94, 95, 96, 97, 162 💬
27 Azithromycin 💬[1] Azithromycin[5] AZITHROMYCIN; AZITHROMYCIN DIHYDRATE; Azithromycin monohydrate; AZITHROMYCINE; Zithromax--[6] 13, 84, 85, 96, 228, 299 💬
28 Azithromycin 💬[1] Azithromycin[5] Azithromycin; AZITHROMYCIN DIHYDRATE; Azithromycin monohydrate; AZITHROMYCINE; ZITHROMAX--[6] 13, 84, 85, 96, 228, 299 💬
29 Baclofen 💬[1] Baclofen[2] Baclofen; Kemstro[2] GABBR1,
GABBR2 💬 		[7] Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬[8] 2, 10, 13, 18, 65, 70, 149, 206 💬
30 Baminercept 💬[1] Baminercept[2] Baminercept; Baminercept alfa[1] LTB 💬 [3] Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[4] 13, 46, 53, 97 💬
31 Belimumab 💬[1] Belimumab[2] Belimumab; Benlysta[1] TNFSF13B 💬 [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[13] 11, 13, 43, 44, 46, 49, 51, 53, 63, 66, 222, 296, 300 💬
32 beta Carotene 💬[1] Beta carotene[3] Beta carotene; Beta-Carotene; BETACAROTENE--[2] 13, 96 💬
33 beta-Alanine 💬[1] beta-Alanine[1] Beta-Alanine--[1] 13 💬
34 Bevacizumab 💬[1] Bevacizumab[2] AVASTIN; Bevacizumab[1] VEGFA 💬 [24] AGE-RAGE signaling pathway in diabetic complications, Bladder cancer, Calcium signaling pathway, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, EGFR tyrosine kinase inhibitor resistance, Fluid shear stress and atherosclerosis, Focal adhesion, HIF-1 signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, MAPK signaling pathway, MicroRNAs in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Renal cell carcinoma, Rheumatoid arthritis, VEGF signaling pathway 💬[6] 13, 34, 85, 87, 227, 280 💬
35 Bexarotene 💬[1] Bexarotene[2] Bexarotene; Targretin[3] RXRA,
RXRB,
RXRG 💬 		[17] Adipocytokine signaling pathway, Bile secretion, Chemical carcinogenesis - receptor activation, Gastric cancer, Hepatitis C, Lipid and atherosclerosis, Non-alcoholic fatty liver disease, Non-small cell lung cancer, PI3K-Akt signaling pathway, PPAR signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Thyroid cancer, Thyroid hormone signaling pathway, Transcriptional misregulation in cancer 💬[2] 13, 75 💬
36 Biotin 💬[1] Biotin[4] Biotin; Biotina; D-BIOTIN; Vitamin B7--[5] 2, 8, 10, 13, 20 💬
37 Bisacodyl 💬[1] Bisacodyl[1] Bisacodyl--[1] 13 💬
38 Bortezomib 💬[1] Bortezomib[3] Bortezomib; Bortezomib Accord; Velcade[1] PSMB5 💬 [8] Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia 💬[17] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 222, 228, 256, 283, 288, 331 💬
39 Botulinum toxin type A 💬[1] Botulinum toxin type A[8] BOTOX; Botulinum toxin A; BOTULINUM TOXIN TYPE A; BTX-A; Dysport; IncobotulinumtoxinA; OnabotulinumtoxinA; Xeomin[1] SNAP25 💬 [2] Insulin secretion, Synaptic vesicle cycle 💬[14] 2, 5, 6, 7, 13, 15, 17, 36, 47, 51, 70, 113, 149, 226 💬
40 Brimonidine 💬[1] Brimonidine[2] Brimonidine; Brimonidine tartrate[3] ADRA2A,
ADRA2B,
ADRA2C 💬 		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[2] 13, 90 💬
41 Butylated hydroxytoluene 💬[1] Butylated hydroxytoluene[0] ---
42 Calcium carbonate 💬[1] Calcium carbonate[3] Calcio carbonato; Calcium; Calcium Carbonate--[9] 13, 19, 46, 53, 75, 96, 235, 274, 299 💬
43 Calcium carbonate 💬[1] Calcium carbonate[3] Calcio carbonato; Calcium; Calcium carbonate--[9] 13, 19, 46, 53, 75, 96, 235, 274, 299 💬
44 Cannabidiol 💬[1] Cannabidiol[4] Cannabidiol; Epidiolex; Epidyolex; SATIVEX[2] CNR1,
CNR2 💬 		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[19] 2, 6, 8, 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
45 Carbamazepine 💬[1] Carbamazepine[1] Carbamazepine[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[3] 6, 13, 231 💬
46 Carbidopa 💬[1] Carbidopa[8] Carbidopa; Carbidopa-Levodopa; DUODOPA; Lodosyn; PARCOPA; SINEMET; SINEMET CR; Stalevo[1] DDC 💬 [9] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Metabolic pathways, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬[7] 6, 13, 17, 90, 140, 164, 201 💬
47 Carbon monoxide 💬[1] Carbon monoxide[1] Carbon Monoxide--[2] 85, 86 💬
48 Carmustine 💬[1] Carmustine[1] Carmustine--[5] 11, 13, 14, 28, 60 💬
49 Cetirizine 💬[1] Cetirizine[3] Cetirizina; Cetirizine; CETIRIZINE HYDROCHLORIDE[1] HRH1 💬 [3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[4] 13, 28, 35, 300 💬
50 Chlormezanone 💬[1] Chlormezanone[0] ---
51 Cholecalciferol 💬[1] Cholecalciferol[5] Cholecalciferol; COLECALCIFEROL; Multivitamin; Vitamin D; Vitamin D3[1] VDR 💬 [5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[16] 6, 13, 19, 20, 34, 46, 49, 51, 53, 60, 65, 96, 97, 228, 298, 299 💬
52 Cisapride 💬[1] Cisapride[1] CISAPRIDE[3] HTR2A,
HTR3A,
HTR4 💬 		[7] Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬[1] 13 💬
53 Cisapride 💬[1] Cisapride[1] CISAPRIDE[3] HTR2A,
HTR3A,
HTR4 💬 		[7] Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬[1] 13 💬
54 Citalopram 💬[1] Citalopram[1] Citalopram[1] SLC6A4 💬 [2] Serotonergic synapse, Synaptic vesicle cycle 💬[7] 6, 8, 13, 18, 46, 98, 127 💬
55 Cladribine 💬[1] Cladribine[4] 2-CdA; CLADRIBINA; CLADRIBINE; MAVENCLAD[1] RRM1 💬 [6] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism 💬[3] 11, 13, 94 💬
56 Clemastine 💬[1] Clemastine[2] Clemastine; CLEMASTINE FUMARATE[1] HRH1 💬 [3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[1] 13 💬
57 Clenbuterol 💬[1] Clenbuterol[1] Clenbuterol[1] ADRB2 💬 [9] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 1, 2, 6, 256 💬
58 Coconut oil 💬[1] Coconut oil[1] Coconut oil--[1] 13 💬
59 Corticotropin 💬[1] Corticotropin[5] ACTH; ACTHar; Adrenocorticotropic hormone; Corticotrophin; Corticotropin[1] MC2R 💬 [5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[12] 2, 13, 14, 46, 49, 50, 66, 75, 81, 84, 145, 222 💬
60 Creatinolfosfate 💬[1] Creatinolfosfate[0] ---
61 Cyanocobalamin 💬[1] Cyanocobalamin[2] Cianocobalamina; Vitamin B12--[5] 6, 13, 201, 229, 299 💬
62 Cyanocobalamin Co 57 💬[1] Cyanocobalamin[2] Cianocobalamina; Vitamin B12--[5] 6, 13, 201, 229, 299 💬
63 Cyanocobalamin Co 58 💬[1] Cyanocobalamin[2] Cianocobalamina; Vitamin B12--[5] 6, 13, 201, 229, 299 💬
64 Cyanocobalamin Co 60 💬[1] Cyanocobalamin[2] Cianocobalamina; Vitamin B12--[5] 6, 13, 201, 229, 299 💬
65 Cyclophosphamide 💬[1] Cyclophosphamide[6] Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; CYCLOPHOSPHAMIDE; Cyclophosphamidum; Cytoxan--[44] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 274, 283, 284, 285, 288, 326, 331 💬
66 Cyclophosphamide 💬[1] Cyclophosphamide[6] Ciclofosfamida; Ciclofosfamide; Cyclophosphamid; Cyclophosphamide; Cyclophosphamidum; Cytoxan--[44] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 274, 283, 284, 285, 288, 326, 331 💬
67 Cytarabine 💬[1] Cytarabine[1] Cytarabine--[7] 11, 13, 14, 25, 49, 60, 65 💬
68 Daclizumab 💬[1] Daclizumab[3] Daclizumab; Zenapax; Zinbryta[1] IL2RA 💬 [11] Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[8] 13, 56, 60, 65, 97, 107, 283, 284 💬
69 Dalfampridine 💬[1] Dalfampridine[7] 4-Aminopyridine; 4-AP; Ampyra; Dalfampridine; FAMPRIDINA; FAMPRIDINE; Fampyra[4] KCNA4,
KCNC3,
KCND2,
KCND3 💬 		[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬[5] 3, 4, 6, 13, 14 💬
70 Dantrolene 💬[1] Dantrolene[2] Dantrolene; Dantrolene sodium--[2] 13, 233 💬
71 Daratumumab 💬[1] Daratumumab[2] Daratumumab; Darzalex[1] CD38 💬 [7] Calcium signaling pathway, Hematopoietic cell lineage, Metabolic pathways, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Salivary secretion 💬[5] 13, 28, 48, 49, 63 💬
72 Darifenacin 💬[1] Darifenacin[2] Darifenacin; Emselex[1] CHRM3 💬 [11] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬[2] 6, 13 💬
73 Decitabine 💬[1] Decitabine[1] Decitabine[3] DNMT1,
DNMT3A,
DNMT3B 💬 		[3] Cysteine and methionine metabolism, Metabolic pathways, MicroRNAs in cancer 💬[2] 60, 63 💬
74 Desloratadine 💬[1] Desloratadine[1] Desloratadine[1] HRH1 💬 [3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[1] 13 💬
75 Dexamethasone 💬[1] Dexamethasone[5] Decadron; Dexametasona; Dexamethasone; Dexamethasone sodium phosphate; Maxidex[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[22] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 81, 84, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬
76 Dexchlorpheniramine 💬[1] Dexchlorpheniramine[1] Dexchlorpheniramine[1] HRH1 💬 [3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[2] 13, 49 💬
77 Dexrazoxane 💬[1] Dexrazoxane[1] Dexrazoxane[2] TOP2A,
TOP2B 💬 		[1] Platinum drug resistance 💬[1] 13 💬
78 Dextromethorphan 💬[1] Dextromethorphan[4] Dextromethorphan; DEXTROMETHORPHAN HYDROBROMIDE; Dextrometorfano; Nuedexta[6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬 		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156 💬
79 Diazoxide 💬[1] Diazoxide[1] Diazoxide[2] ABCC8,
KCNJ11 💬 		[4] ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬[2] 13, 193 💬
80 Diclofenac 💬[1] Diclofenac[3] Diclofenac; Diclofenac sodium; Diclofenac SR[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[5] 13, 34, 46, 78, 271 💬
81 Dimethyl fumarate 💬[1] Dimethyl fumarate[3] Dimethyl fumarate; Dimethylfumarat; TECFIDERA[1] KEAP1 💬 [6] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Parkinson disease, Pathways in cancer, Ubiquitin mediated proteolysis 💬[5] 13, 49, 51, 86, 296 💬
82 Diphenhydramine 💬[1] Diphenhydramine[2] Diphenhydramine; Diphenhydramine hydrochloride[1] HRH1 💬 [3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[8] 11, 13, 49, 51, 70, 86, 222, 256 💬
83 Diroximel fumarate 💬[1] Diroximel fumarate[1] Diroximel Fumarate--[1] 13 💬
84 Dirucotide 💬[1] Dirucotide[1] Dirucotide--[1] 13 💬
85 Domperidone 💬[1] Domperidone[1] Domperidone[1] DRD2 💬 [8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[5] 6, 13, 17, 51, 230 💬
86 Domperidone maleate 💬[1] Domperidone[1] Domperidone[1] DRD2 💬 [8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[5] 6, 13, 17, 51, 230 💬
87 Donepezil 💬[1] Donepezil[3] ARICEPT; Donepezil; Donepezil hydrochloride[1] ACHE 💬 [2] Cholinergic synapse, Glycerophospholipid metabolism 💬[9] 5, 6, 13, 46, 78, 124, 127, 156, 206 💬
88 Doxycycline 💬[1] Doxycycline[4] Doxycyclin; Doxycycline; Doxycycline Hyclate; Doxycycline Tablets--[17] 13, 23, 28, 34, 46, 84, 85, 89, 96, 97, 158, 161, 162, 167, 227, 280, 299 💬
89 Doxycycline 💬[1] Doxycycline[4] Doxycyclin; Doxycycline; DOXYCYCLINE HYCLATE; Doxycycline Tablets--[17] 13, 23, 28, 34, 46, 84, 85, 89, 96, 97, 158, 161, 162, 167, 227, 280, 299 💬
90 Dronabinol 💬[1] Dronabinol[4] DELTA-9-TETRAHYDROCANNABINOL; DRONABINOL; SATIVEX; Tetrahydrocannabinol[2] CNR1,
CNR2 💬 		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[7] 2, 8, 13, 36, 46, 271, 298 💬
91 Dulaglutide 💬[1] Dulaglutide[2] Dulaglutide; Trulicity[1] GLP1R 💬 [3] Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[2] 13, 299 💬
92 Duloxetine 💬[1] Duloxetine[3] Cymbalta; DULOXETINE; Duloxetine hydrochloride[2] SLC6A2,
SLC6A4 💬 		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[2] 6, 13 💬
93 Dydrogesterone 💬[1] Dydrogesterone[1] DYDROGESTERONE[1] PGR 💬 [5] Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬[1] 13 💬
94 Eculizumab 💬[1] Eculizumab[2] ECULIZUMAB; SOLIRIS[1] C5 💬 [11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[7] 11, 13, 14, 61, 62, 109, 222 💬
95 Efalizumab 💬[1] Efalizumab[2] EFALIZUMAB; Raptiva[1] ITGAL 💬 [12] Cell adhesion molecules, Epstein-Barr virus infection, Human T-cell leukemia virus 1 infection, Leukocyte transendothelial migration, Malaria, Natural killer cell mediated cytotoxicity, Neutrophil extracellular trap formation, Rap1 signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Staphylococcus aureus infection, Viral myocarditis 💬[9] 11, 13, 37, 46, 49, 53, 61, 95, 96 💬
96 Elasomeran 💬[1] Moderna COVID-19 Vaccine[4] COVID-19 Vaccine Moderna; Elasomeran; Moderna COVID-19 Vaccine; Spikevax--[5] 13, 46, 51, 65, 299 💬
97 Elezanumab 💬[1] Elezanumab[1] Elezanumab[1] RGMA 💬 [2] Axon guidance, TGF-beta signaling pathway 💬[1] 13 💬
98 Escitalopram 💬[1] Escitalopram[3] Citalopram; Escitalopram; Escitalopram oxalate[1] SLC6A4 💬 [2] Serotonergic synapse, Synaptic vesicle cycle 💬[4] 2, 6, 13, 46 💬
99 Esomeprazole 💬[1] Esomeprazole[3] Esomeprazole; Nexium; Omeprazole[2] ATP4A,
ATP4B 💬 		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[8] 13, 46, 86, 98, 107, 113, 298, 299 💬
100 Estradiol 💬[1] Estradiol[1] Estradiol[2] ESR1,
ESR2 💬 		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[7] 13, 46, 49, 65, 76, 226, 299 💬
101 Estriol 💬[1] Estriol[1] Estriol[2] ESR1,
ESR2 💬 		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[2] 13, 227 💬
102 Estriol tripropionate 💬[1] Estriol[1] Estriol[2] ESR1,
ESR2 💬 		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[2] 13, 227 💬
103 Eszopiclone 💬[1] Eszopiclone[2] Eszopiclone; Zopiclone[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[3] 6, 13, 46 💬
104 Ethinyl estradiol 💬[1] Ethinylestradiol[3] Ethinyl estradiol; ETHINYLESTRADIOL; Ortho-Novum 777[1] ESR1 💬 [9] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[4] 13, 46, 49, 299 💬
105 Etoposide 💬[1] Etoposide[1] Etoposide[2] TOP2A,
TOP2B 💬 		[1] Platinum drug resistance 💬[11] 11, 13, 14, 26, 28, 34, 60, 65, 85, 164, 331 💬
106 Evobrutinib 💬[1] Evobrutinib[1] Evobrutinib[1] BTK 💬 [7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[3] 13, 46, 49 💬
107 Famciclovir 💬[1] Famciclovir[1] Famciclovir--[2] 11, 13 💬
108 Febuxostat 💬[1] Febuxostat[1] Febuxostat[1] XDH 💬 [6] Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Peroxisome, Purine metabolism 💬[3] 2, 6, 13 💬
109 Fenebrutinib 💬[1] Fenebrutinib[1] FENEBRUTINIB[1] BTK 💬 [7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[1] 13 💬
110 Ferric oxide 💬[1] Ferric oxide[1] Iron oxide--[1] 13 💬
111 Ferumoxytol 💬[1] Ferumoxytol[2] Feraheme; Ferumoxytol--[1] 13 💬
112 Fexofenadine 💬[1] Fexofenadine[1] Fexofenadine[1] HRH1 💬 [3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[2] 13, 46 💬
113 Filgrastim 💬[1] Filgrastim[7] Filgrastim; Filgrastim Hexal; G-CSF; Granulocyte Colony Stimulating Factor; Neupogen; TEVAGRASTIM; Zarzio[1] CSF3R 💬 [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[35] 2, 6, 11, 13, 16, 22, 25, 26, 28, 34, 35, 36, 38, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
114 Fingolimod 💬[1] Fingolimod[3] Fingolimod; FINGOLIMOD HYDROCHLORIDE; Gilenya[1] S1PR1 💬 [3] FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬[3] 13, 14, 156 💬
115 Firategrast 💬[1] Firategrast[1] Firategrast[1] ITGA4 💬 [14] Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Human papillomavirus infection, Hypertrophic cardiomyopathy, Intestinal immune network for IgA production, Leishmaniasis, Leukocyte transendothelial migration, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Yersinia infection 💬[1] 13 💬
116 Fludarabine 💬[1] Fludarabine[4] FLUDARA; Fludarabina; Fludarabine; Fludarabine Phosphate[1] RRM1 💬 [6] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism 💬[20] 11, 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326 💬
117 Flumazenil 💬[1] Flumazenil[1] Flumazenil[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[5] 6, 13, 17, 18, 206 💬
118 Fluoxetine 💬[1] Fluoxetine[5] Fluoxetin; Fluoxetine; FLUOXETINE HYDROCHLORIDE; Fluoxétine; PROZAC[1] SLC6A4 💬 [2] Serotonergic synapse, Synaptic vesicle cycle 💬[6] 13, 17, 78, 86, 179, 206 💬
119 Flupirtine 💬[1] Flupirtine[1] Flupirtine--[1] 13 💬
120 Flurbiprofen 💬[1] Flurbiprofen[1] Flurbiprofen[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[3] 13, 21, 46 💬
121 Fumaric acid 💬[1] Fumaric acid[1] Fumaric acid--[1] 13 💬
122 Gabapentin 💬[1] Gabapentin[4] GABAPENTIN; GABAPENTINA; Gabapentine; NEURONTIN[5] CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4,
SLC6A1 💬 		[9] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, GABAergic synapse, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway, Synaptic vesicle cycle 💬[5] 6, 13, 19, 70, 298 💬
123 Gadobenic acid 💬[1] Gadobenic acid[2] Gadobenate; MultiHance--[3] 13, 86, 88 💬
124 Gadobutrol 💬[1] Gadobutrol[1] Gadobutrol--[2] 13, 22 💬
125 Gadoteric acid 💬[1] Gadoteric acid[2] Dotarem; Gadoteric acid--[1] 13 💬
126 Gadoteridol 💬[1] Gadoteridol[1] Gadoteridol--[1] 13 💬
127 Gamolenic acid 💬[1] Gamolenic acid[2] Gamma-Linolenic acid; Linolenic acid--[1] 46 💬
128 Ginseng 💬[1] Ginseng[1] Ginseng--[3] 13, 46, 53 💬
129 Glycerin 💬[1] Glycerin[2] Bee venom; Glycerol--[5] 6, 13, 79, 316, 317 💬
130 Guanabenz 💬[1] Guanabenz[1] GUANABENZ[3] ADRA2A,
ADRA2B,
ADRA2C 💬 		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[2] 2, 13 💬
131 Histidine 💬[1] Histidine[2] Histidine; L-Histidine--[3] 13, 169, 170 💬
132 Hydrochlorothiazide 💬[1] Hydrochlorothiazide[2] Esidrix; HYDROCHLOROTHIAZIDE[1] SLC12A3 💬 [1] 💬[4] 13, 67, 225, 235 💬
133 Hydroxychloroquine 💬[1] Hydroxychloroquine[3] Hydroxychloroquine; HYDROXYCHLOROQUINE SULFATE; Plaquenil--[27] 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299 💬
134 Hydroxyurea 💬[1] Hydroxyurea[1] Hydroxyurea[1] RRM2 💬 [7] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Nucleotide metabolism, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway 💬[8] 3, 13, 19, 20, 65, 85, 86, 284 💬
135 Ibudilast 💬[1] Ibudilast[1] Ibudilast[8] CYSLTR1,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PTGIR 💬 		[16] Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action, Platelet activation, Progesterone-mediated oocyte maturation, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 2, 13 💬
136 Ibuprofen 💬[1] Ibuprofen[2] Ibuprofen; IBUPROFEN 200MG[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[7] 13, 46, 65, 107, 113, 271, 299 💬
137 Idebenone 💬[1] Idebenone[2] Idebenone; Raxone--[6] 6, 8, 13, 18, 113, 302 💬
138 Imatinib 💬[1] Imatinib[4] Gleevec; GLIVEC; Imatinib; Imatinib mesylate[3] ABL1,
KIT,
PDGFRA 💬 		[32] Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬[12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
139 Indapamide 💬[1] Indapamide[1] Indapamide[1] SLC12A3 💬 [1] 💬[1] 13 💬
140 Inebilizumab 💬[1] Inebilizumab[2] INEBILIZUMAB; Uplizna[1] CD19 💬 [5] B cell receptor signaling pathway, Epstein-Barr virus infection, Hematopoietic cell lineage, PI3K-Akt signaling pathway, Primary immunodeficiency 💬[4] 11, 13, 51, 300 💬
141 Inosine 💬[1] Inosine[1] Inosine--[5] 2, 6, 13, 17, 122 💬
142 Interferon alfa 💬[1] Interferon alfa[1] Interferon alfa[2] IFNAR1,
IFNAR2 💬 		[18] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬[5] 25, 26, 28, 56, 96 💬
143 Interferon beta-1a 💬[1] Interferon beta-1a[6] AVONEX; Interferon Beta 1-A; Interferon Beta 1a; Interferon beta-1a; Interferon-beta-1a; REBIF[2] IFNAR1,
IFNAR2 💬 		[18] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬[4] 13, 26, 96, 97 💬
144 Interferon beta-1b 💬[1] Interferon beta-1b[7] BETAFERON; Betaseron; EXTAVIA; Interferon beta 1B; INTERFERON BETA-1B; Interferon-beta-1b; RECOMBINANT INTERFERON BETA-1B[2] IFNAR1,
IFNAR2 💬 		[18] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬[1] 13 💬
145 Isoxsuprine 💬[1] Isoxsuprine[2] Isoxsuprine; Isoxsuprine Hydrochloride[1] ADRB2 💬 [9] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 13 💬
146 Ixazomib 💬[1] Ixazomib[2] Ixazomib; Ninlaro[1] PSMB5 💬 [8] Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia 💬[5] 13, 16, 28, 51, 61 💬
147 Josamycin 💬[1] Josamycin[0] ---
148 Ketamine 💬[1] Ketamine[2] KETAMINE; NMDA[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[6] 6, 13, 70, 113, 156, 215 💬
149 Ketoconazole 💬[1] Ketoconazole[2] Ketoconazole; NIZORAL[1] CYP17A1 💬 [6] Cortisol synthesis and secretion, Cushing syndrome, Metabolic pathways, Ovarian steroidogenesis, Prolactin signaling pathway, Steroid hormone biosynthesis 💬[3] 8, 13, 75 💬
150 Lactobacillus casei 💬[1] Lactobacillus casei[2] Fusion; Lactobacillus casei--[10] 6, 11, 13, 46, 49, 69, 70, 97, 271, 296 💬
151 Lactose 💬[1] Lactose[1] Lactose--[6] 2, 6, 13, 97, 228, 310 💬
152 Lactulose 💬[1] Lactulose[1] Lactulose--[3] 13, 96, 291 💬
153 Lamotrigine 💬[1] Lamotrigine[2] Lamictal; LAMOTRIGINE[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[5] 13, 34, 38, 114, 144 💬
154 Lenograstim 💬[1] Lenograstim[2] G-CSF; Lenograstim[1] CSF3R 💬 [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[7] 2, 13, 16, 18, 19, 57, 65 💬
155 Levetiracetam 💬[1] Levetiracetam[2] KEPPRA; Levetiracetam[1] SV2A 💬 [1] ECM-receptor interaction 💬[5] 2, 4, 6, 13, 307 💬
156 Levocarnitine 💬[1] Levocarnitine[4] Carnitine; L-Carnitine; Levocarnitine; Xyzal--[11] 3, 5, 13, 53, 58, 86, 96, 97, 265, 298, 316 💬
157 Levonorgestrel 💬[1] Levonorgestrel[1] LEVONORGESTREL[1] PGR 💬 [5] Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬[1] 13 💬
158 Lidocaine 💬[1] Lidocaine[4] Aloe; Lidocaine; Lignocaine; Xylocaine[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
159 Lidocaine hydrochloride monohydrate 💬[1] Lidocaine[4] Aloe; Lidocaine; Lignocaine; Xylocaine[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[13] 6, 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
160 Liothyronine 💬[1] Liothyronine[3] Liothyronine; Liothyronine sodium; Triiodothyronine[2] THRA,
THRB 💬 		[2] Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬[4] 13, 78, 210, 212 💬
161 Lisdexamfetamine 💬[1] Lisdexamfetamine[1] Lisdexamfetamine[2] SLC6A2,
SLC6A3 💬 		[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[1] 13 💬
162 Lithium carbonate 💬[1] Lithium carbonate[2] Lithium; Lithium Carbonate--[5] 2, 13, 17, 18, 127 💬
163 Loperamide 💬[1] Loperamide[2] LOPERAMIDE; Loperamide hydrochloride[3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[2] 13, 97 💬
164 Loratadine 💬[1] Loratadine[2] Loratadina; Loratadine[1] HRH1 💬 [3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[4] 13, 46, 89, 98 💬
165 Lubiprostone 💬[1] Lubiprostone[1] Lubiprostone[1] CLCN2 💬 [1] Mineral absorption 💬[4] 6, 13, 290, 299 💬
166 Lysine 💬[1] Lysine[1] Lysine--[4] 13, 97, 228, 299 💬
167 Maltodextrin 💬[1] Maltodextrin[1] Maltodextrin--[4] 6, 13, 96, 97 💬
168 Mangafodipir 💬[1] Mangafodipir[1] Mangafodipir--[1] 13 💬
169 Mannitol 💬[1] Mannitol[4] Aridol; Bronchitol; Mannite; Mannitol--[7] 6, 13, 28, 60, 96, 113, 299 💬
170 Masitinib 💬[1] Masitinib[1] Masitinib[1] KIT 💬 [11] Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer, Hematopoietic cell lineage, MAPK signaling pathway, Melanogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway 💬[6] 2, 5, 6, 13, 46, 96 💬
171 Medroxyprogesterone acetate 💬[1] Medroxyprogesterone acetate[1] Medroxyprogesterone[1] PGR 💬 [5] Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬[1] 49 💬
172 Melatonin 💬[1] Melatonin[2] Circadin; Melatonin[2] MTNR1A,
MTNR1B 💬 		[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬[12] 6, 8, 13, 37, 46, 49, 72, 78, 90, 97, 145, 202 💬
173 Melphalan 💬[1] Melphalan[3] ALKERAN; Melphalan; Melphalan Hydrochloride--[15] 11, 13, 14, 19, 20, 28, 60, 62, 65, 96, 164, 234, 284, 285, 299 💬
174 Memantine 💬[1] Memantine[3] Ebixa; Memantine; MEMANTINE HYDROCHLORIDE[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[8] 2, 6, 8, 13, 49, 127, 205, 206 💬
175 Meningococcal polysaccharide vaccine group A 💬[1] Meningococcal polysaccharide vaccine group A[2] MENVEO; Nimenrix--[7] 11, 13, 50, 61, 62, 66, 222 💬
176 Meningococcal polysaccharide vaccine group C 💬[1] Meningococcal polysaccharide vaccine group C[2] Menveo; Nimenrix--[7] 11, 13, 50, 61, 62, 66, 222 💬
177 Metformin 💬[1] Metformin[5] Metformin; Metformin HCl; Metformin hydrochloride; Metformina; Metformine[2] PRKAA1,
PRKAA2 💬 		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[25] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
178 Methotrexate 💬[1] Methotrexate[6] Methotrexat; Methotrexate; METHOTREXATE SODIUM; METOJECT; Metotrexato; Méthotrexate[2] DHFR,
DHFR2 💬 		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
179 Methylphenidate 💬[1] Methylphenidate[3] Methylphenidate; METHYLPHENIDATE HYDROCHLORIDE; Ritalin[2] SLC6A2,
SLC6A3 💬 		[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[7] 6, 13, 34, 84, 113, 179, 206 💬
180 Methylprednisolone 💬[1] Methylprednisolone[4] Medrol; Methylprednisolon; Methylprednisolone; Methylprednisolone acetate[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[46] 2, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬
181 Methylprednisolone hemisuccinate 💬[1] Methylprednisolone hemisuccinate[4] Methylprednisolone hemisuccinate; Methylprednisolone sodium succinate; Methylprednisolone succinate; SOLU-MEDROL[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[7] 13, 49, 50, 51, 53, 97, 211 💬
182 Midazolam 💬[1] Midazolam[2] Midazolam; Midazolam injection[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
183 Minocycline 💬[1] Minocycline[3] Minocycline; MINOCYCLINE HYDROCHLORIDE; Minomycin--[14] 2, 6, 8, 13, 46, 84, 85, 90, 94, 162, 201, 206, 280, 299 💬
184 Mirabegron 💬[1] Mirabegron[1] Mirabegron[1] ADRB3 💬 [8] Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, cGMP-PKG signaling pathway 💬[4] 6, 13, 53, 226 💬
185 Mitoxantrone 💬[1] Mitoxantrone[2] Mitoxantrone; Novantrone[2] TOP2A,
TOP2B 💬 		[1] Platinum drug resistance 💬[1] 13 💬
186 Modafinil 💬[1] Modafinil[2] Modafinil; Provigil--[5] 6, 13, 49, 93, 113 💬
187 Monomethyl fumarate 💬[1] Monomethyl fumarate[2] Bafiertam; Monomethyl fumarate--[1] 13 💬
188 Montelukast 💬[1] Montelukast[3] Montelukast; MONTELUKAST SODIUM; Singulair[1] CYSLTR1 💬 [2] Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬[8] 6, 13, 46, 61, 63, 85, 98, 228 💬
189 Mycophenolate mofetil 💬[1] Mycophenolate mofetil[3] CELLCEPT; Mycophenolate mofetil; Mycophenolate mofetil TEVA[2] IMPDH1,
IMPDH2 💬 		[4] Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬[34] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
190 Mycophenolic acid 💬[1] Mycophenolic acid[5] Acido Micofenolico; MICOFENOLICO ACIDO; Mycophenolate; Mycophenolic Acid; Myfortic[2] IMPDH1,
IMPDH2 💬 		[4] Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬[36] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
191 Nabilone 💬[1] Nabilone[1] Nabilone[2] CNR1,
CNR2 💬 		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[3] 6, 13, 127 💬
192 Nabiximols 💬[1] Nabiximols[1] Nabiximols--[1] 13 💬
193 Naltrexone 💬[1] Naltrexone[2] Naltrexone; Naltrexone Hydrochloride[3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[12] 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬
194 Naproxen 💬[1] Naproxen[5] Naprosyn; Naproxen; Naproxen oral suspension; NAPROXEN SODIUM; Propanoic acid[2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[4] 13, 46, 107, 271 💬
195 Natalizumab 💬[1] Natalizumab[2] NATALIZUMAB; TYSABRI[1] ITGA4 💬 [14] Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Human papillomavirus infection, Hypertrophic cardiomyopathy, Intestinal immune network for IgA production, Leishmaniasis, Leukocyte transendothelial migration, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Yersinia infection 💬[6] 13, 15, 25, 46, 63, 96 💬
196 Nicotine 💬[1] Nicotine[2] Nicotine; Nicotine gum[16] CHRNA1,
CHRNA10,
CHRNA2,
CHRNA3,
CHRNA4,
CHRNA5,
CHRNA6,
CHRNA7,
CHRNA9,
CHRNB1,
CHRNB2,
CHRNB3,
CHRNB4,
CHRND,
CHRNE,
CHRNG 💬 		[8] Alzheimer disease, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Virion - Lyssavirus 💬[3] 6, 13, 84 💬
197 Nitrofurantoin 💬[1] Nitrofurantoin[1] Nitrofurantoin--[1] 13 💬
198 Nivolumab 💬[1] Nivolumab[1] Nivolumab[1] PDCD1 💬 [3] Cell adhesion molecules, PD-L1 expression and PD-1 checkpoint pathway in cancer, T cell receptor signaling pathway 💬[12] 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬
199 Nomegestrol 💬[1] Nomegestrol[1] Nomegestrol[1] PGR 💬 [5] Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬[1] 13 💬
200 Nomegestrol acetate 💬[1] Nomegestrol acetate[1] Nomegestrol acetate[1] PGR 💬 [5] Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬[1] 13 💬
201 Norethindrone 💬[1] Norethisterone[3] Norethindrone; Ortho-novum; Ortho-Novum 777[1] PGR 💬 [5] Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬[4] 13, 46, 49, 299 💬
202 Ocrelizumab 💬[1] Ocrelizumab[3] Ocrelizumab; OCREVUS; RhuMAb 2H7[1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[3] 13, 46, 49 💬
203 Ofatumumab 💬[1] Ofatumumab[4] Arzerra; HuMax-CD20; Kesimpta; OFATUMUMAB[1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[3] 13, 35, 46 💬
204 Oleic acid 💬[1] Oleic Acid[1] Oleic Acid--[2] 13, 299 💬
205 Olesoxime 💬[1] Olesoxime[1] Olesoxime--[3] 2, 3, 13 💬
206 Olive oil 💬[1] Olive oil[1] Olive oil--[5] 13, 35, 49, 53, 162 💬
207 Opicinumab 💬[1] Opicinumab[1] Opicinumab[1] LINGO1 💬 [1] 💬[1] 13 💬
208 Orelabrutinib 💬[1] Orelabrutinib[1] Orelabrutinib[1] BTK 💬 [7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[4] 13, 49, 61, 63 💬
209 Oxcarbazepine 💬[1] Oxcarbazepine[2] Oxcarbazepine; Trileptal[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[1] 13 💬
210 Oxybutynin 💬[1] Oxybutynin[1] Oxybutynin[5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬 		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[3] 6, 13, 53 💬
211 Oxycodone 💬[1] Oxycodone[2] Oxycodone; OXYCODONE HYDROCHLORIDE[3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[5] 6, 13, 70, 226, 298 💬
212 Oxyquinoline 💬[1] Oxyquinoline[1] Oxine--[1] 13 💬
213 Ozanimod 💬[1] Ozanimod[2] OZANIMOD; Zeposia[5] S1PR1,
S1PR2,
S1PR3,
S1PR4,
S1PR5 💬 		[3] FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬[3] 13, 96, 97 💬
214 Palifermin 💬[1] Palifermin[2] Kepivance; Palifermin[1] FGFR2 💬 [13] Calcium signaling pathway, Central carbon metabolism in cancer, EGFR tyrosine kinase inhibitor resistance, Endocytosis, Gastric cancer, MAPK signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Signaling pathways regulating pluripotency of stem cells 💬[5] 13, 36, 38, 39, 65 💬
215 Pantoprazole 💬[1] Pantoprazole[1] Pantoprazole[2] ATP4A,
ATP4B 💬 		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[2] 13, 65 💬
216 Paroxetine 💬[1] Paroxetine[1] Paroxetine[1] SLC6A4 💬 [2] Serotonergic synapse, Synaptic vesicle cycle 💬[4] 6, 13, 46, 85 💬
217 Peginterferon beta-1a 💬[1] Peginterferon beta-1a[2] PEGINTERFERON BETA-1A; Plegridy[2] IFNAR1,
IFNAR2 💬 		[18] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬[1] 13 💬
218 Penciclovir 💬[1] Penciclovir[0] ---
219 Pertussis vaccine 💬[1] Pertussis vaccine[1] Pertussis vaccine--[2] 13, 46 💬
220 Phenytoin 💬[1] Phenytoin[1] Phenytoin[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[1] 13 💬
221 Pioglitazone 💬[1] Pioglitazone[1] PIOGLITAZONE[1] PPARG 💬 [11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[17] 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
222 Pirfenidone 💬[1] Pirfenidone[2] Esbriet; PIRFENIDONE[6] CCL2,
IL10,
IL1A,
IL1B,
IL6,
TNF 💬 		[84] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Autoimmune thyroid disease, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemokine signaling pathway, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Staphylococcus aureus infection, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
223 Pixantrone 💬[1] Pixantrone[1] PIXANTRONE[2] TOP2A,
TOP2B 💬 		[1] Platinum drug resistance 💬[2] 11, 13 💬
224 Polyethylene glycol 3350 💬[1] Polyethylene glycol[4] Macrogol; Macrogol 4000; Polyethylene glycol; Polyethylene Glycol 3350--[7] 6, 78, 96, 97, 235, 276, 299 💬
225 Ponesimod 💬[1] Ponesimod[2] PONESIMOD; Ponvory[1] S1PR1 💬 [3] FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬[1] 13 💬
226 Pravastatin 💬[1] Pravastatin[2] Pravastatin; Pravastatin sodium[1] HMGCR 💬 [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[9] 13, 46, 49, 67, 79, 96, 164, 265, 333 💬
227 Prednisolone 💬[1] Prednisolone[3] Prednisolona; Prednisolone; Prednisolonum[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[42] 3, 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
228 Prednisone 💬[1] Prednisone[3] PREDNISONA; PREDNISONE; RAYOS[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[45] 2, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 💬
229 Pregabalin 💬[1] Pregabalin[2] Lyrica; Pregabalin[4] CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4 💬 		[7] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway 💬[5] 13, 36, 46, 70, 298 💬
230 Prucalopride 💬[1] Prucalopride[2] Prucalopride; Resolor[1] HTR4 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Serotonergic synapse, cAMP signaling pathway 💬[3] 13, 51, 96 💬
231 Pyrimethamine 💬[1] Pyrimethamine[2] Daraprim; Pyrimethamine--[4] 2, 4, 19, 65 💬
232 Quetiapine 💬[1] Quetiapine[2] Quetiapine; Seroquel[2] DRD2,
HTR2A 💬 		[11] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬[2] 6, 13 💬
233 Quinidine 💬[1] Quinidine[4] Nuedexta; Quinidina; Quinidine; Quinidine Sulfate[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[3] 2, 8, 13 💬
234 Raltegravir 💬[1] Raltegravir[2] ISENTRESS; Raltegravir--[4] 13, 26, 93, 265 💬
235 Ramatroban 💬[1] Ramatroban[1] Ramatroban[2] PTGDR,
TBXA2R 💬 		[3] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Platelet activation 💬[1] 13 💬
236 Ranitidine 💬[1] Ranitidine[1] Ranitidine[1] HRH2 💬 [3] Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬[2] 13, 65 💬
237 Ravulizumab 💬[1] Ravulizumab[2] RAVULIZUMAB; Ultomiris[1] C5 💬 [11] Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬[7] 2, 11, 13, 50, 62, 66, 109 💬
238 Remibrutinib 💬[1] Remibrutinib[1] Remibrutinib[1] BTK 💬 [7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[2] 13, 53 💬
239 Rifampin 💬[1] Rifampicin[2] Rifampicin; Rifampin--[9] 6, 13, 17, 46, 84, 86, 93, 299, 338 💬
240 Riluzole 💬[1] Riluzole[2] Rilutek; Riluzole[14] GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[23] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[9] 2, 3, 5, 8, 13, 17, 18, 203, 206 💬
241 Rimabotulinumtoxin B 💬[1] Botulinum toxin type B[3] Botulinum toxin type B; MYOBLOC; NEUROBLOC[1] SNAP25 💬 [2] Insulin secretion, Synaptic vesicle cycle 💬[4] 2, 6, 13, 51 💬
242 Rituximab 💬[1] Rituximab[6] MabThera; Rituxan; Rituximab; Rixathon; Ruxience; Truxima[1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[48] 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
243 Rivastigmine 💬[1] Rivastigmine[3] EXELON; Rivastigmine; Rivastigmine Transdermal System[1] ACHE 💬 [2] Cholinergic synapse, Glycerophospholipid metabolism 💬[3] 5, 6, 13 💬
244 Rolipram 💬[1] Rolipram[1] Rolipram[4] PDE4A,
PDE4B,
PDE4C,
PDE4D 💬 		[5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬[2] 8, 13 💬
245 Satralizumab 💬[1] Satralizumab[3] Enspryng; Sapelizumab; SATRALIZUMAB[1] IL6R 💬 [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[3] 11, 13, 86 💬
246 Secukinumab 💬[1] Secukinumab[2] COSENTYX; SECUKINUMAB[1] IL17A 💬 [6] Alcoholic liver disease, Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Inflammatory bowel disease, Rheumatoid arthritis, Th17 cell differentiation 💬[8] 13, 37, 41, 46, 107, 160, 269, 271 💬
247 Silodosin 💬[1] Silodosin[2] Silodosin; Silodyx[1] ADRA1A 💬 [7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[2] 6, 13 💬
248 Simethicone 💬[1] Simethicone[1] Simethicone--[2] 13, 96 💬
249 Simvastatin 💬[1] Simvastatin[3] Simvastatin; Simvastatina; Simvastatine[1] HMGCR 💬 [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[21] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
250 Siponimod 💬[1] Siponimod[2] Mayzent; Siponimod[2] S1PR1,
S1PR5 💬 		[3] FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬[2] 13, 50 💬
251 Sirolimus 💬[1] Sirolimus[3] RAPAMUNE; Rapamycin; Sirolimus[1] MTOR 💬 [51] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[40] 2, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
252 Sivelestat 💬[1] Sivelestat[1] Sivelestat[1] ELANE 💬 [3] Neutrophil extracellular trap formation, Systemic lupus erythematosus, Transcriptional misregulation in cancer 💬[3] 13, 85, 96 💬
253 Sodium chloride 💬[1] Sodium chloride[6] Lactated Ringers; Natriumchlorid; REBIF; Saline; Sodium chloride; SPORANOX--[20] 6, 11, 13, 14, 34, 41, 46, 50, 51, 53, 60, 67, 70, 96, 168, 193, 227, 228, 288, 299 💬
254 Solifenacin 💬[1] Solifenacin[2] Solifenacin; Solifenacin Succinate[1] CHRM3 💬 [11] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬[3] 6, 13, 53 💬
255 Somatorelin 💬[1] Somatorelin[2] GHRH; Somatorelin[1] GHRHR 💬 [2] Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction 💬[2] 13, 78 💬
256 Spectinomycin 💬[1] Spectinomycin[0] ---
257 Suvorexant 💬[1] Suvorexant[1] Suvorexant[2] HCRTR1,
HCRTR2 💬 		[1] Neuroactive ligand-receptor interaction 💬[3] 5, 6, 13 💬
258 Tacrolimus 💬[1] Tacrolimus[2] Prograf; Tacrolimus[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
259 Tacrolimus 💬[1] Tacrolimus[2] Prograf; Tacrolimus[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
260 Tamsulosin 💬[1] Tamsulosin[1] Tamsulosin[3] ADRA1A,
ADRA1B,
ADRA1D 💬 		[7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 13 💬
261 Tarenflurbil 💬[1] Tarenflurbil[2] FLURBIPROFEN; Tarenflurbil[4] APH1A,
NCSTN,
PSEN1,
PSENEN 💬 		[6] Alzheimer disease, Human papillomavirus infection, Neurotrophin signaling pathway, Notch signaling pathway, Pathways of neurodegeneration - multiple diseases, Wnt signaling pathway 💬[1] 13 💬
262 Temsirolimus 💬[1] Temsirolimus[1] Temsirolimus[1] MTOR 💬 [51] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[1] 13 💬
263 Tenofovir 💬[1] Tenofovir[1] Tenofovir--[6] 2, 13, 25, 93, 265, 325 💬
264 Tenofovir alafenamide 💬[1] Tenofovir alafenamide[1] Tenofovir alafenamide--[2] 2, 13 💬
265 Teriflunomide 💬[1] Teriflunomide[2] AUBAGIO; TERIFLUNOMIDE[1] DHODH 💬 [3] Biosynthesis of cofactors, Metabolic pathways, Pyrimidine metabolism 💬[3] 13, 25, 26 💬
266 Testosterone 💬[1] Testosterone[1] Testosterone[1] AR 💬 [4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[8] 1, 2, 3, 13, 60, 76, 78, 113 💬
267 Testosterone undecanoate 💬[1] Testosterone undecanoate[1] Testosterone undecanoate[1] AR 💬 [4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[2] 13, 60 💬
268 Tetracycline 💬[1] Tetracycline[2] Tetracyclin; Tetracycline--[5] 13, 36, 46, 53, 97 💬
269 Thiotepa 💬[1] Thiotepa[1] Thiotepa--[12] 13, 19, 20, 28, 51, 60, 65, 85, 96, 164, 284, 285 💬
270 Thymol 💬[1] Thymol[1] Thymol--[1] 13 💬
271 Tioguanine 💬[1] Tioguanine[0] [1] HPRT1 💬 [4] Drug metabolism - other enzymes, Metabolic pathways, Nucleotide metabolism, Purine metabolism 💬-
272 Tizanidine 💬[1] Tizanidine[1] Tizanidine[3] ADRA2A,
ADRA2B,
ADRA2C 💬 		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[1] 13 💬
273 Tocilizumab 💬[1] Tocilizumab[3] ACTEMRA; RoActemra; Tocilizumab[1] IL6R 💬 [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[21] 2, 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
274 Tocopherol 💬[1] Tocopherol[2] Tocoferol; Tocopherol--[6] 13, 49, 90, 206, 257, 298 💬
275 Tolperisone 💬[1] Tolperisone[1] Tolperisone--[1] 13 💬
276 Tozinameran 💬[1] Tozinameran[2] Comirnaty; Tozinameran--[5] 13, 46, 51, 53, 299 💬
277 Treosulfan 💬[1] Treosulfan[2] OVASTAT; TREOSULFAN--[6] 13, 19, 62, 65, 283, 286 💬
278 Ublituximab 💬[1] Ublituximab[1] UBLITUXIMAB[1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[1] 13 💬
279 Valproic acid 💬[1] Valproic acid[3] Valproate; VALPROATE SODIUM; Valproic acid[7] ABAT,
ALDH5A1,
CACNA1G,
CACNA1H,
CACNA1I,
GAD1,
GAD2 💬 		[17] Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬[10] 2, 3, 5, 26, 65, 90, 102, 222, 233, 256 💬
280 Vancomycin 💬[1] Vancomycin[1] Vancomycin--[8] 13, 46, 70, 94, 96, 97, 296, 299 💬
281 Vardenafil 💬[1] Vardenafil[3] Levitra; Vardenafil; Vardenafilo[1] PDE5A 💬 [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[3] 13, 86, 299 💬
282 Venlafaxine 💬[1] Venlafaxine[2] Venlafaxine; Venlafaxine Hydrochloride[2] SLC6A2,
SLC6A4 💬 		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[3] 6, 13, 46 💬
283 Vitamin A 💬[1] Vitamin A[1] Vitamin A[2] RARA,
RARB 💬 		[8] Acute myeloid leukemia, Estrogen signaling pathway, Gastric cancer, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer 💬[3] 13, 53, 90 💬
284 Vitamin E 💬[1] Vitamin E[2] Alpha-tocopherol; Vitamin E--[12] 2, 6, 13, 20, 46, 49, 90, 96, 97, 206, 299, 317 💬
285 Warfarin 💬[1] Warfarin[2] Warfarin; Warfarin Sodium[2] NQO1,
VKORC1 💬 		[7] Biosynthesis of cofactors, Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Metabolic pathways, Pathways in cancer, Ubiquinone and other terpenoid-quinone biosynthesis 💬[11] 6, 8, 13, 19, 46, 49, 66, 85, 86, 88, 91 💬
286 Water 💬[1] Water[8] AVONEX; ENBREL; Hiberix; Indocyanine green; OMNITROPE; Sterile Water for Injection; Water; WATER FOR INJECTION--[21] 2, 5, 6, 13, 17, 22, 35, 46, 53, 57, 63, 65, 67, 78, 84, 96, 97, 206, 226, 278, 299 💬
287 Zanubrutinib 💬[1] Zanubrutinib[1] Zanubrutinib[1] BTK 💬 [7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[5] 13, 63, 222, 300, 331 💬
288 Zoledronic acid 💬[1] Zoledronic acid[4] Aclasta; Zoledronate; ZOLEDRONIC ACID; Zometa[1] FDPS 💬 [4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[13] 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
289 Zoledronic acid 💬[1] Zoledronic acid[4] Aclasta; Zoledronate; Zoledronic Acid; Zometa[1] FDPS 💬 [4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬[13] 5, 6, 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬