Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Acetylcysteine 💬[1] Acetylcysteine[4] Acetylcysteine; N acetyl cysteine; N-Acetyl cysteine; N-acetylcysteine--[25] 2, 6, 13, 19, 20, 21, 34, 49, 51, 53, 58, 63, 85, 90, 94, 97, 111, 164, 193, 233, 296, 298, 299, 303, 337 💬
2 Air, medical 💬[1] Medical air[1] Medical air--[3] 85, 86, 193 💬
3 Anastrozole 💬[1] Anastrozole[1] Anastrozole[1] CYP19A1 💬 [2] Ovarian steroidogenesis, Steroid hormone biosynthesis 💬[3] 78, 86, 193 💬
4 Cannabidiol 💬[1] Cannabidiol[1] Cannabidiol[2] CNR1,
CNR2 💬 		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[20] 6, 8, 13, 19, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
5 Carbetocin 💬[1] Carbetocin[1] Carbetocin[1] OXTR 💬 [5] Calcium signaling pathway, Hormone signaling, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬[1] 193 💬
6 Choline 💬[1] Choline[2] Choline; Choline Chloride--[4] 93, 171, 193, 299 💬
7 Diazoxide 💬[1] Diazoxide[2] Diazoxide; DIAZOXIDE CHOLINE[2] ABCC8,
KCNJ11 💬 		[4] ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬[2] 13, 193 💬
8 Diazoxide choline 💬[1] Diazoxide[2] Diazoxide; DIAZOXIDE CHOLINE[2] ABCC8,
KCNJ11 💬 		[4] ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬[2] 13, 193 💬
9 Exenatide 💬[1] Exenatide[1] Exenatide[1] GLP1R 💬 [4] Hormone signaling, Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[6] 6, 17, 72, 78, 193, 233 💬
10 Guanfacine 💬[1] Guanfacine[1] Guanfacine[1] ADRA2A 💬 [4] Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[1] 193 💬
11 Guanfacine hydrochloride 💬[1] Guanfacine[1] Guanfacine[1] ADRA2A 💬 [4] Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[1] 193 💬
12 Liraglutide 💬[1] Liraglutide[1] LIRAGLUTIDE[1] GLP1R 💬 [4] Hormone signaling, Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[5] 6, 13, 75, 77, 193 💬
13 Metoprolol 💬[1] Metoprolol[2] Metoprolol; Metoprolol succinate[1] ADRB1 💬 [13] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 17, 57, 58, 113, 193, 226 💬
14 Metoprolol fumarate 💬[1] Metoprolol[2] Metoprolol; Metoprolol Succinate[1] ADRB1 💬 [13] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 17, 57, 58, 113, 193, 226 💬
15 Metoprolol succinate 💬[1] Metoprolol[2] Metoprolol; METOPROLOL SUCCINATE[1] ADRB1 💬 [13] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 17, 57, 58, 113, 193, 226 💬
16 Metoprolol tartrate 💬[1] Metoprolol[2] Metoprolol; METOPROLOL SUCCINATE[1] ADRB1 💬 [13] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 17, 57, 58, 113, 193, 226 💬
17 Metyrapone 💬[1] Metyrapone[1] Metyrapone[1] CYP11B1 💬 [3] Cortisol synthesis and secretion, Cushing syndrome, Steroid hormone biosynthesis 💬[2] 75, 193 💬
18 Octreotide 💬[1] Octreotide[4] OCTREOTIDA; OCTREOTIDE; OCTREOTIDE ACETATE; OCTREOTIDE HYDROCHLORIDE[1] SSTR2 💬 [5] Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[8] 67, 75, 77, 84, 85, 89, 193, 227 💬
19 Octreotide acetate 💬[1] Octreotide[4] OCTREOTIDA; OCTREOTIDE; OCTREOTIDE ACETATE; OCTREOTIDE HYDROCHLORIDE[1] SSTR2 💬 [5] Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[8] 67, 75, 77, 84, 85, 89, 193, 227 💬
20 Octreotide acetate 💬[1] Octreotide[4] OCTREOTIDA; Octreotide; OCTREOTIDE ACETATE; OCTREOTIDE HYDROCHLORIDE[1] SSTR2 💬 [5] Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[8] 67, 75, 77, 84, 85, 89, 193, 227 💬
21 Octreotide hydrochloride 💬[1] Octreotide[4] OCTREOTIDA; OCTREOTIDE; OCTREOTIDE ACETATE; OCTREOTIDE HYDROCHLORIDE[1] SSTR2 💬 [5] Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[8] 67, 75, 77, 84, 85, 89, 193, 227 💬
22 Octreotide pamoate 💬[1] Octreotide[4] OCTREOTIDA; OCTREOTIDE; OCTREOTIDE ACETATE; OCTREOTIDE HYDROCHLORIDE[1] SSTR2 💬 [5] Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[8] 67, 75, 77, 84, 85, 89, 193, 227 💬
23 Oxygen 💬[1] Oxygen[1] Oxygen--[30] 6, 13, 15, 19, 22, 36, 46, 49, 70, 71, 85, 86, 88, 90, 96, 97, 129, 149, 168, 193, 211, 226, 230, 235, 269, 271, 294, 298, 299, 330 💬
24 Oxytocin 💬[1] Oxytocin[1] Oxytocin[1] OXTR 💬 [5] Calcium signaling pathway, Hormone signaling, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬[8] 6, 70, 72, 127, 168, 193, 206, 226 💬
25 Pitolisant 💬[1] Pitolisant[1] Pitolisant[1] HRH3 💬 [2] Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[3] 6, 113, 193 💬
26 Pitolisant hydrochloride 💬[1] Pitolisant[1] Pitolisant[1] HRH3 💬 [2] Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[3] 6, 113, 193 💬
27 Rimonabant 💬[1] Rimonabant[1] Rimonabant[1] CNR1 💬 [4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[1] 193 💬
28 Setmelanotide 💬[1] Setmelanotide[1] Setmelanotide[1] MC4R 💬 [3] Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[5] 134, 193, 202, 236, 265 💬
29 Setmelanotide acetate 💬[1] Setmelanotide[1] Setmelanotide[1] MC4R 💬 [3] Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[5] 134, 193, 202, 236, 265 💬
30 Sodium chloride 💬[1] Sodium chloride[3] NaCl; Sodium chloride; Sodium Chloride solution--[31] 2, 6, 11, 13, 14, 22, 34, 41, 46, 50, 51, 53, 60, 65, 67, 70, 85, 96, 97, 124, 168, 193, 214, 215, 226, 227, 228, 271, 288, 298, 299 💬
31 Tirzepatide 💬[1] Tirzepatide[1] Tirzepatide[2] GIPR,
GLP1R 💬 		[4] Hormone signaling, Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[6] 67, 96, 97, 193, 233, 265 💬
32 Topiramate 💬[1] Topiramate[1] TOPIRAMATE[37] CA2,
CA4,
CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ,
GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬 		[55] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Arrhythmogenic right ventricular cardiomyopathy, Bile secretion, Cadherin signaling, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Huntington disease, Hypertrophic cardiomyopathy, IgSF CAM signaling, Insulin secretion, Long-term depression, Long-term potentiation, MAPK signaling pathway, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Nitrogen metabolism, Oxytocin signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Prion disease, Proximal tubule bicarbonate reclamation, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Tight junction, Transcriptional misregulation in cancer, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 6, 97, 140, 144, 156, 193 💬